Momma yensua nnuru foforo a ɛtew srade so (PCSK9 Inhibitors) ho ade?

So wo duruyɛfo aka akyerɛ wo sɛ wo srade a ɛwɔ wo mu no dɔɔso? Sɛ saa a, ebia wɔafi ase de statin bi anom. Mpɛn pii no, ɛno ne ayaresa a edi kan. Nanso ɛtɔ mmere bi a saa aduru no nkutoo nnɔɔso. Anaasɛ nnipa binom ntumi nnyina aduru no mu nsunsuanso bɔne no ano. Ɛno nti na mprempren nnuruyɛfo reka nnuru foforo a ɛyɛ ‘agoru-sesa’ ho asɛm no. Wɔfrɛ eyinom PCSK9 Inhibitors. Momma yɛnka wɔn ho asɛm wɔ nsɛm a ɛnyɛ den mu nnɛ.

Sɛ yɛbɛka no tiawa a, dɛn ne saa PCSK9 Inhibitors yi?

Eyinom yɛ nnuru foforo a ebetumi atew srade ‘bɔne’, anaa LDL srade , a ɛwɔ yɛn mogya mu no so yiye. Mprempren nnuru ahorow atitiriw abien na wɔapene so wɔ wiase. Wɔn ne `alirocumab (Praluent)` ne `evolocumab (Repatha)`.

Nhwehwɛmu ada no adi sɛ saa nnuru yi a wɔfrɛ no PCSK9 inhibitors no tu mpɔn ma ɛyɛ nwonwa. Wɔ tebea horow bi mu no, wobetumi asiw komayare ne akisikuru ano mpo . Wobetumi anom saa nnuru yi nkutoo, anaasɛ wɔde aka statin aduru a wonom dedaw ho. Nanso ade biako a ɛsɛ sɛ yɛma ɛtra yɛn adwenem ne sɛ ne bo yɛ den koraa sen nnuru afoforo a ɛma srade yɛ kɛse .

Okay, afei momma yɛnhwɛ sɛnea saa aduru yi yɛ adwuma wɔ nipadua no mu.

Sɛ yɛbɛte eyi ase a, momma yensusuw asɛm ketewaa bi ho. Akwaa titiriw a ɛhwɛ srade a ɛwɔ yɛn nipadua mu so ne mmerɛbo.

Nanso, protein foforo bi wɔ hɔ a wɔfrɛ no PCSK9 a yɛn nipadua yɛ. N'adwuma ne sɛ ɛbɛhwehwɛ na asɛe saa "ahotewfo" pa no. Afei, esiane sɛ obiara nni hɔ a obeyi srade no afi hɔ nti, ɛboaboa ano wɔ mogya no mu na ɛkɔhyɛ ntini no afasu mu.

Eyi ne baabi a yɛn ɔkasafo, aduru a esiw PCSK9 ano no ba bɛboa. Nea saa aduru yi yɛ ne sɛ ɛkyere saa PCSK9 protein bɔne no na ɛmma ɛnyɛ adwuma. Ɛte sɛ nea woakyere abofra a ɔyɛ ɔkwasea de no ato akongua mu. Afei yɛn "ahotewfo" betumi ayɛ wɔn adwuma a akwanside biara nni ho. Nea afi mu aba? LDL srade dodow a ɛwɔ mogya mu no so tew ntɛmntɛm.

Ɔkwan bɛn so na eyinom yɛ soronko wɔ ‘statins’ ho?

Statin ne PCSK9 inhibitors yɛ nnuru ahorow abien a ɛtew srade so, nanso ɛyɛ adwuma wɔ akwan horow abien so. Saa pon yi bɛboa wo ma woate eyi ase.

Enti hena na ɔpɛ sɛ ɔnom saa aduru yi?

Eyi yɛ asɛmmisa a ɛho hia efisɛ ɛnyɛ obiara a ɔwɔ srade pii na ohia saa aduru yi. Wo duruyɛfo bedi kan abɔ mmɔden sɛ ɔde statin bedi wo srade a ɛwɔ wo mogya mu no so. Nanso ebia wo duruyɛfo besusuw PCSK9 inhibitor ho wɔ nsɛm a edidi so yi mu:

• Awosu mu srade a ɛkɔ soro tebea: Nnipa binom wɔ awosu mu tebea bi a wɔfrɛ no ``Familial Hypercholesterolemia.'' Saa nkurɔfo yi wɔ sintɔ bi wɔ ɔkwan a wɔn nipadua fa so di srade so no mu. Sɛ wɔde statin dodow a ɛsen biara mpo di dwuma a, ɛyɛ den yiye ma saa nkurɔfo yi sɛ wɔbɛma LDL srade no akɔ fam akodu baabi a ɛfata.
• Wɔ nnipa a asiane kɛse wom sɛ wobenya komayare anaa akisikuru fam no: Sɛ wowɔ komayare dedaw, na wɔmfa nnuru te sɛ statin nni wo srade dodow so yiye a, ebia wo duruyɛfo besusuw saa aduru yi ho.
• Wɔn a wontumi nnye ‘statins’ ntom no: Nnipa a wɔnom statin no mu bɛyɛ 10%-20% nya nsunsuanso bɔne te sɛ ntini mu yaw a wontumi nnyina ano, mmerɛwyɛ, ne nipadua mu yaw . Wɔ saa nkurɔfo no fam no, ebia eyi bɛyɛ ɔkwan pa a wobetumi afa so.

Bere bɛn na oduruyɛfo no ma saa aduru yi?

Oduruyɛfo remma aduru yi prɛko pɛ da. Ɔkwan bi wɔ hɔ a wɔfa so yɛ no.

1. Nea edi kan no, sesa w’asetra kwan: Oduruyɛfo no di kan ka sɛ teɛteɛ w’apɔw mu yiye na di nnuan a ahoɔden wom a ngo, asikre, ne esiam kakraa bi na ɛwom .

2. Afei, ‘Statin’: Sɛ asetra mu nsakrae nnɔɔso a, wofi ase de statin di dwuma. Sɛ srade a ɛwɔ mogya mu no ankɔ fam a, wɔde nkakrankakra ma dodow no kɔ soro.

3. Sɛ́ ɔkwan a etwa to: Sɛ wɔantumi anhyɛ wo srade mu srade so wɔ statin dodow a ɛsen biara mpo mu, anaasɛ sɛ nea efi mu ba no mu yɛ den a, ɛnde wo duruyɛfo betumi asusuw PCSK9 inhibitor ho. Wobetumi asi gyinae yi denam sɔhwɛ bi te sɛ ahrawa mu calcium nkyerɛwde a wɔbɛyɛ de ahwɛ asiane a ɛwɔ hɔ sɛ wubenya komayare no so.

Ɔkwan bɛn so na wɔde saa aduru yi di dwuma na dɛn ne nea efi mu ba?

Ɛba sɛ aduru a wɔde twitwiw honam ani a wode ma wɔ honam ani adapɛn abien anaa anan biara . Wubetumi anya bi wɔ wo yafunu, w’asen atifi, anaa wo nsa atifi were mu. Wo duruyɛfo anaa ɔyarehwɛfo a wɔatete no bɛkyerɛ wo sɛnea wode bɛma no yiye. Mpɛn pii no, ɛnyɛ yaw na ɛnyɛ den.

Sɛ ɛba nsunsuanso bɔne so a, nea ɛtaa ba no yɛ nketenkete.

• Akyi a ɛyɛ yaw
• Nsɛnkyerɛnne a ɛte sɛ atiridii (menewa a ɛyɛ yaw, nsu a ɛyɛ nwini a ɛba) .
• Kɔkɔɔ, akuru, anaa ɛyaw kakra wɔ baabi a wɔde aduru no guu no

Nea etwa to no, sɛ ɛba nnuru yi ho ka so a, ɛnte sɛ nnuru a wɔde di dwuma daa, na ne bo yɛ den yiye . Enti, ebia obiara ntumi ntɔ saa ayaresa yi. Ɛyɛ papa sɛ wo ne wo duruyɛfo bɛbɔ eyi ho nkɔmmɔ pefee na woasusuw ho sɛ ebia wuhia, sɛ ebia ɛfata wo, ne nea wubetumi apaw sɛ wobɛbɔ ka.