So worehyia honam ani akuru a emu yɛ den mpofirim? Momma yensua Pyoderma Gangrenosum ho ade!

So woanya akisikuru ketewaa bi anaa kɔkɔɔ bi wɔ wo honam ani a efii ase sɛ akisikuru ketewaa anaa akisikuru kɔkɔɔ na mpofirim ara ɛdanee akuru kɛse a ɛyɛ yaw pɛn? Ebetumi asi wɔ mmeae bɛboro biako, nanso ebetumi asi wɔ mmeae pii nso wɔ wo nipadua no so. Eyi yɛ tebea a ɛhwehwɛ sɛ wɔde adwene si so kakra ankasa na ebetumi ayɛ den kakra. Ɛnnɛ yɛrebɛka honam ani yare bi a wɔfrɛ no Pyoderma Gangrenosum ho asɛm, a ɛyɛ tebea a ɛntaa nsi nanso ɛho hia yiye sɛ ɛsɛ sɛ wohu. Mma ɛnhaw wo, momma yɛmma ɛnyɛ mmerɛw.

Dɛn ne Pyoderma Gangrenosum yi?

Sɛ yɛbɛka no tiawa a, pyoderma gangrenosum yɛ honam ani yare a enni sabea , a ɛkyerɛ sɛ ɛtra hɔ kyɛ, na ɛsan ba bio . Nea ɛba ne sɛ wo honam ani di kan fi ase nya akisikuru nketenkete a ne kɔla asesa (ebia kɔkɔɔ, kɔkɔɔ, bruu, bruu, anaa tuntum), anaasɛ akisikuru a nsu ahyɛ mu ma (bullae). Nea asiane wom kɛse ne sɛ eyinom betumi anyin ntɛmntɛm, ayɛ biako, na abɛyɛ akuru a emu dɔ na abue (akuru) .

Susuw sɛnea anka ɛbɛyɛ sɛ biribi fi ase sɛ akisikuru ketewaa bi na wɔ nna kakraa bi mu dan akuru a ɛyɛ yaw a ne kɛse te sɛ nikel? Saa na ɛkɔ so wɔ ha. Ebia nnipa binom benya akuru biako pɛ, nanso sɛ emu yɛ den a, akuru pii betumi aba prɛko pɛ. Saa akuru yi betumi ayɛ yaw kɛse .

Nea ɛho hia no, mpɛn pii no, pyoderma gangrenosum ne nhyehyɛe mu nyarewa afoforo wɔ abusuabɔ , a ɛkyerɛ sɛ ɛnyɛ honam ani haw ara kwa.

Hena na ɛda adi kɛse sɛ obenya eyi?

Pyoderma gangrenosum betumi aba wɔ mfe biara mu, nanso ɛntaa nsi koraa wɔ mmofra mu . Ɛtaa ba mmea a wɔadi fi mfe 20 kosi 50. Ebia ɛbɛyɛ mmerɛw nso sɛ wubenya pyoderma gangrenosum sɛ wowɔ tebea horow a edidi so yi mu biara a:

• Rheumatoid arthritis - Eyi ye yare a ɛma nkwaa no ho hyehye.
• Ulcerative colitis - Tebea a ɛyɛ hyew a ɛwɔ akuru wɔ dwensɔtwaa kɛse no mu.
• Crohn yareɛ - Ɔyare foforɔ a ɛba wɔ aduane mu.
• Kokoram ahorow bi, sɛ nhwɛso no, mogya mu kokoram te sɛ mogya mu kokoram anaa mogya mu kokoram.

Wɔkyerɛ sɛ ɛba nnipa bɛyɛ ɔha biara mu biako mu wɔ United States . Ɛno kyerɛ sɛ ɛnyɛ nea abu so saa.

Eyi ka nipadua no dɛn? Dɛn ne sɛnkyerɛnne ahorow no?

Pyoderma gangrenosum ma wo honam ani akisikuru nketenkete a ne kɔla sesa ne ɔfe, a ɛkyerɛ sɛ ɛho wosow na ɛyɛ kɔkɔɔ. Saa akisikuru yi betumi apue wɔ nipadua no mu baabiara, nanso wɔtaa hu no wɔ nan, nansoaa, ne anan (afã a ɛwɔ fam) so .

Saa akisikuru yi betumi apae ntɛmntɛm, adan akuru akɛse a ɛyɛ yaw, na atrɛw.Nsɛnkyerɛnne titiriw a ɛkyerɛ ne sɛ:

• Nkuru nketenkete a ne kɔla asesa (kɔkɔɔ, kɔkɔɔ, bruu, bruu, anaa tuntum) a akisikuru ahyɛ mu ma. Eyinom trɛw ntɛmntɛm .
• Akuru a abue (akuru) ba. Nsonsonoe a atwa saa akuru yi ho ahyia no kɔ soro na wotumi hu pefee .
• Kuru no ho ahonhon ne ɛyaw a emu yɛ den .
• Ebia nnipa binom benya atiridii .
• Nkwaa mu yaw nso betumi aba.

Ɛtɔ mmere bi a, saa akuru yi tumi yɛ akɛse paa na emu dɔ , na ɛyaw no betumi ayɛ nea wontumi nnyina ano.

Nhwehwɛmu bi ada no adi sɛ nnipa a wɔwɔ pyoderma gangrenosum no mu bɛyɛ 70% betumi anya tebea foforo bɛboro biako (comorbidities) bere koro mu. Sɛ wɔde pyoderma gangrenosum ka tebea afoforo ho a, wɔka sɛ asiane a ɛwɔ hɔ sɛ obi bewu no betumi akɔ soro akodu 30%. Enti, eyi nyɛ biribi a ɛsɛ sɛ wobu no adewa.

So eyi yɛ yare a nipadua no tumi ko tia nyarewa?

Yiw, wogye di sɛ pyoderma gangrenosum yɛ yare a nipadua no tumi ko tia nyarewa . Sɛ yɛbɛka no tiawa a, wo nipadua no ankasa ahobammɔ nhyehyɛe, nipadua no mu tumi a ɛko tia nyarewa, tow hyɛ w’ankasa wo honam ani nkwammoaa so. Wɔ nnipa binom fam no, pyoderma gangrenosum gyae bere a wɔasa tebea afoforo a yɛaka ho asɛm wɔ atifi hɔ no.

Dɛn nti na pyoderma gangrenosum nya nkɔso?

Aduruyɛ ho abenfo da so ara nnim nea ɛde ba ankasa , nanso nnipa a wɔwɔ pyoderma gangrenosum no mu bɛboro fã wɔ tebea afoforo (te sɛ ntini mu yare, mogya mu kokoram, ne Crohn yare), sɛnea yɛadi kan aka no.

Nea ɛka ho no, pyoderma gangrenosum nso betumi aba bere a wapira honam ani, akisikuru, anaa oprehyɛn (pathergy) akyi . Fa no sɛ wo nsa mu akisikuru ketewaa bi, anaasɛ oprehyɛn ketewaa bi, na ɛha na yare yi betumi afi ase. Ɛtɔ mmere bi a, saa akuru yi nso nyin twa stoma beae bi ho hyia bere a wɔayɛ oprehyɛn awie no. Wɔfrɛ eyi sɛ peristomal pyoderma gangrenosum.

So eyi yɛ ɔyare mmoawa?

Dabi, Pyoderma gangrenosum nyɛ nea wɔde yare mmoawa ba . Ɛntumi ntrɛw mfi onipa biako mu nkɔ foforo mu denam honam ani honam ani hwɛbea a ɛne ne ho di nkitaho no so. Eyi yɛ ade a ɛhaw nnipa pii, enti ɛho hia sɛ yɛma eyi mu da hɔ.

Ɔkwan bɛn so na nnuruyɛfo hu eyi?

Sɛ yɛbɛka nokware a, pyoderma gangrenosum a wobehu no betumi ayɛ den kakra . Sɔhwɛ biara nni hɔ a edi mũ a ebetumi asi so dua sɛ ɛyɛ tebea no. Enti, nnuruyɛfo taa yɛ nhwehwɛmu de hu tebea afoforo a ebetumi de honam ani haw a ɛte saa ara aba. Ɛne sɛ, wodi kan hwɛ hu sɛ tebea afoforo a ɛwɔ sɛnkyerɛnne a ɛte saa ara nni hɔ. Nhwɛsoɔ:

• Nyarewa ahorow ahorow.
• Honam ani kokoram ahorow.
• Mogya ntini a ɛyɛ hyew wɔ honam ani.
• Lupus yare no.
• Tebea bi a wɔfrɛ no Sweet syndrome.

Ebia sɔhwɛ ahorow a wɔde bɛyɛ eyi no bi ne:

• Mogya mu nhwehwɛmu.
• Wora ketewaa bi a wobɛfa akɔyɛ nhwehwɛmu (Biopsy).
• Bone marrow sampling - titire se wosusu se nneɛma te sɛ mogya mu kokoram a.
• Proctoscopy a wɔde hwɛ nipadua no mu.
• Colonoscopy - se wosusu se tebea te se Crohn yare no a.

Bere a wɔayɛ nhwehwɛmu ahorow yi nyinaa na wɔapow biribiara akyi nkutoo na oduruyɛfo no de ba awiei sɛ ɛyɛ pyoderma gangrenosum.

Dɛn ne ayaresa ahorow no?

Ayaresa ahorow pii wɔ hɔ a wobetumi apaw ama pyoderma gangrenosum. Ɛho hia sɛ wohu yare no ntɛm na wɔsa yare na wɔasiw akuru ano .

Ayaresa a wɔde ma wɔ nsɛm a ɛtaa ba, a emu nyɛ den pii ho

Sɛ akuru no mu nyɛ den dodo a, oduruyɛfo no betumi akyerɛw nnuru a wɔde gu nipadua no so anaa srade a wɔde gu nipadua no so. Eyinom bi ne:

• Corticosteroids: Eyinom yɛ nnuru a ɛtew ɔfe so. Wobetumi de apete akuru so sɛ aduru a wɔde yɛ aduru anaasɛ wɔbɛnom sɛ nnuru a wɔde yɛ nnuru. Nhwɛso ahorow: cortisone, prednisone. Nanso, eyinom betumi anya nsunsuanso bɔne te sɛ aduan ho akɔnnɔ a ɛkɔ soro, mu duru a ɛkɔ soro, adwene a ɛsakra, akisikuru, ne nna a wontumi nna.
• Nnuru a ɛnyɛ steroid a ɛko tia ɔyare mmoawa (NSAID): Eyinom yɛ nnuru a ɛma ɛyaw ano brɛ ase. Nhwɛso ahorow: aspirin, ibuprofen. Eyinom betumi ama gas , ahurututu, yafunu mu yaw, akisikuru, ɔfe, akisikuru, ne akisikuru.
• Silver sulfadiazine skin cream: Nokwarem no, eyi yɛ aduru a ekum ɔyare mmoawa a wɔde gu ɔhyew so de siw ɔyare mmoawa ano. Ɛtɔ mmere bi a wɔde di dwuma ma tebea yi nso. Ebetumi ama ne ho ayɛ no yaw, atiridiinini, awɔw, honam ani akuru, ne owia hann a ɔte nka.

Katee kakra?

Sɛ opira no mu yɛ den kɛse a, oduruyɛfo no betumi akyerɛw ayaresa ahorow te sɛ eyinom:

• Nnuru a ɛma nipadua no tumi ko tia nyarewa: Eyinom yɛ adwuma denam tumi a wo nipadua mu tumi a ɛko tia nyarewa no tumi sɛe n’ankasa nipadua no so. Nhwɛso ahorow: mycophenolate, cyclosporine.
• Biologic agents: Eyinom yɛ nnuru ahorow foforo. Wɔnam protein pɔtee bi a ɛwɔ nipadua no mu a ɛde ɔfe ba a wɔde wɔn ani si so so na ɛyɛ adwuma. Nhwɛso ahorow: infliximab, adalimumab, ustekinumab.
• Hyperbaric oxygen therapy: Eyi hwehwɛ sɛ wɔde oxygen 100% ma wɔ dan titiriw bi mu. Wɔkyerɛ sɛ ɛma nipadua mu ntini ahorow sa ntɛmntɛm.

Momma yensua oprehyɛn ho ade nso.

Wɔ tebea horow bi mu no, ebia oprehyɛn a wɔde yi ntini a awuwu fi kuru no mu (debriding) no bɛboa. Nanso, eyi nso wɔ asiane ahorow .Esiane sɛ honam ani yare a ɛsɛe (pathergy) betumi ama pyoderma gangrenosum ho sɛnkyerɛnne no ayɛ kɛse nti, ɛsɛ sɛ wode ahwɛyiye kɛse yɛ eyi na wo duruyɛfo no pɛ.

Ɛtɔ mmere bi a wobetumi ayɛ honam ani aduru a wɔde hyɛ nipadua no mu. Eyi kyerɛ sɛ woyi were fi nipadua no fã bi a ɛwɔ apɔwmuden mu na wɔde kɔ baabi a kuru no wɔ no.

Dɛn na ɛsɛ sɛ wuhu sɛ obi a ɔwɔ saa tebea yi?

Sɛ wowɔ pyoderma gangrenosum a, ahodwiriw biara a ɛba wo honam ani – ntwitwiridii, nsensanee, akuru – betumi ama wo sɛnkyerɛnne ahorow no asɛe kɛse . Enti ɛsɛ sɛ wohwɛ yiye sɛnea wubetumi biara. Fa no sɛ woreyɛ adwuma wɔ turo mu anaa adididan mu, na sɛ wobɔ wo ho kakra mpo a, ebetumi abɛyɛ ɔhaw kɛse.

Afei nso, akuru a wobɛma ɛho atew no ho hia na amma ɔyare mmoawa ankɔ so .

• Fa nsu a ɛho tew a ɛsen ne samina hohoro akuru no yiye.
• Afei, fa ahwɛyiye fa aduru a wɔde kyekyere kuru no so. Eyi remma efĩ ne mmoawa ntumi nkɔ mu.
• Wo honam ani yare ho ɔyaresafo bɛma wo nsɛm pii afa sɛnea wobɛma kuru no ho atew ne sɛnea wode aduru bɛbɔ honam ani. Di saa akwankyerɛ ahorow no akyi yiye.
• Sɛ wɔama wo srade bi a, hohoro kuru no, fa ngo no gu so, na afei kyekyere ho.

Sɛ wopɛ akuru a emu yɛ den a, ebia wo duruyɛfo bɛkamfo akyerɛ sɛ fa hydrocolloid aduru a wɔde kyekyere wo ho . Eyinom bɔ kuru no ho ban na ankɔ so anwene ne ɔyare mmoawa. Wɔbɛ "abɔ" akɔ honam ani wɔ nnansa kosi nnansa ntam.

Bere tenten ahe na egye ansa na asa?

Pyoderma gangrenosum yɛ tebea a ɛyɛ den sɛ wɔbɛsa . Sɛ wɔsa akuru no yiye mpo a, ebetumi agye adapɛn pii, ɛtɔ mmere bi a asram pii ansa na ayɛ yiye. Enti, ɛsɛ sɛ wunya abotare.

So wobetumi asiw eyi ano?

Esiane sɛ wonnim nea ɛde ba ankasa nti, ɛyɛ den sɛ yɛbɛka ɔkwan a wɔbɛfa so asiw ano no yiye . Nanso, sɛ wowɔ asiane ahorow te sɛ mogya mu kokoram anaa dwensɔtwaa mu yare a ɛma ɛyɛ hyew, na wunya honam ani haw foforo biara (titiriw akuru a enyin ntɛmntɛm) , ka kyerɛ wo duruyɛfo ntɛm ara . Bisa wo duruyɛfo sɛ ɔmfa wo nkɔ honam ani yare ho oduruyɛfo anaa oduruyɛfo foforo a ɔwɔ osuahu wɔ pyoderma gangrenosum ho nkyɛn.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Akyinnye biara nni ho sɛ ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn wɔ nsɛm yi mu:

• Sɛ wowɔ dwensɔtwaa mu yare a ɛma ɛyɛ hyew, ntini mu yare, anaa mogya mu yare bi na wunya akisikuru anaa akuru a ɛyɛ kɛse ntɛmntɛm a .
• Sɛ ɛte sɛ nea wo kuru no anya ɔyare mmoawa (kɔkɔɔ, kɔkɔɔ, fitaa anaa fitaa, ahonhon, anaasɛ ɛyɛ yaw).
• Sɛ wunya sɛnkyerɛnne foforo a .
• Sɛ wunya nsunsuanso bɔne a emu yɛ den bere a woanom aduru no akyi a.

Nsɛmmisa a ɛho hia a ɛsɛ sɛ wubisa wo duruyɛfo

Sɛ wokɔ oduruyɛfo nkyɛn a, ɛho hia paa sɛ wubisa nsɛm yi:

• Ɔkwan bɛn so ankasa na woka sɛ mewɔ pyoderma gangrenosum?
• Sɛ minni pyoderma gangrenosum a, honam ani yare foforo bɛn na ebetumi ayɛ?
• Sɔhwɛ ahorow bɛn na wohwɛ kwan sɛ wobɛyɛ?
• Aduru anaa ayaresa bɛn na wokamfo kyerɛ?
• So wubetumi ama me cream bi a mede bɛpetepete so anaa aduru bi a mɛnom?
• Dɛn ne nnuru ne ayaresa ahorow yi mu nsunsuanso bɔne a wɔahyehyɛ no nyinaa?
• Dɛn bio na ɛsɛ sɛ meyɛ na ama me yare no ho sɛnkyerɛnne so atew?
• So ɛsɛ sɛ mekɔ honam ani yare ho oduruyɛfo, plastic oprehyɛn ho oduruyɛfo, yafunu mu yare ho oduruyɛfo, nipadua mu ahoɔden a ɛko tia nyarewa ho oduruyɛfo, anaa oduruyɛfo foforo?

Ɛho hia paa sɛ wubisa saa nsɛm yi na wunya wo tebea no ho ntease a emu da hɔ.

Nsonsonoe bɛn na ɛda Pyoderma Gangrenosum ne Ecthyma Gangrenosum ntam?

Saa edin abien yi di nsɛ kakra, enti wobetumi afrafra.

Ecthyma gangrenosum yɛ honam ani yare a ɛntaa nsi a Pseudomonas bacteraemia, mmoawa a wɔtaa hu wɔ nsu ne asase mu na ɛde ba. Ebetumi nso ama honam ani akuru ne ntini a atwa ho ahyia no awuwu. Ɛtaa ka nnipa a wɔn nipadua mu tumi a ɛko tia nyarewa no ayɛ mmerɛw .

Pyoderma gangrenosum nso ma honam ani akuru ba. Wonnim nea ɛde ba ankasa. Wosusuw sɛ ɛyɛ ɔyare a nipadua no tumi ko tia nyarewa. Nanso, ɛnyɛ tebea a ɛka nnipa a wɔn nipadua mu tumi a ɛko tia nyarewa no ayɛ mmerɛw titiriw .

So pyoderma gangrenosum akuru ahorow wɔ hɔ?

Yiw, pyoderma gangrenosum akuru atitiriw anan na ɛwɔ hɔ:

• Classic pyoderma gangrenosum: Eyi ne nea abu so sen biara. Mpɛn pii no, akuru a ɛyɛ yaw ba nan no so.
• Atypical anaa bullous pyoderma gangrenosum: Saa ɔkwan yi da adi sɛ akisikuru a nsu ahyɛ mu ma. Wɔtaa hu no wɔ nsa so. Ɛtaa ba nnipa a wɔwɔ mogya mu kokoram mu.
• Pustular pyoderma gangrenosum: Ɛda adi sɛ akisikuru nketewa a akisikuru ahyɛ mu ma (pustules) wɔ nsa ne anan so. Eyi taa ba nnipa a wɔwɔ dwensɔtwaa mu yare a ɛma obi ho hyehye no so.
• Vegetative pyoderma gangrenosum: Mpɛn pii no, saa akuru yi nyɛ yaw.

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

Pyoderma gangrenosum yɛ tebea a efi ase sɛ akisikuru nketenkete wɔ honam ani na ebetumi adan akuru akɛse ntɛmntɛm. Ebetumi ayɛ den sɛ wubehu yare no na woasa , enti ɛsɛ sɛ wo ne wo duruyɛfo nyinaa nya abotare.

Kae sɛ ɛho hia yiye sɛ wohwɛ yiye wɔ ahodwiriw biara a ɛbɛba wo honam ani, efisɛ eyi betumi ama woanya akuru foforo.

Sɛ pyoderma gangrenosum mu yɛ den na wowɔ nyarewa afoforo a ɛka ho a, ebetumi ama woate ɛyaw kɛse, akuru, na ɛde ɔhaw ahorow a ɛde wo nkwa to asiane mu mpo aba. Enti, sɛ wowɔ yare bi a nipadua no tumi ko tia nyarewa na worehyia honam ani akuru a enyin ntɛmntɛm a, kɔ oduruyɛfo ntɛm ara. Sɛ wuhu ntɛm na wosa wo yare a, ebetumi aboa wo ma wo ho atɔ wo. Mma wo ho nnyɛ wo hu , nanso hwɛ yiye.

` Pyoderma Gangrenosum, Honam ani Nyarewa, Akuru, Akuru, Nkwammoaa a ɛko tia nyarewa, Honam ani yare, Nyarewa a Enni sabea