Ɛyɛ ade a ɛfata sɛ ehu ne dadwen kakra bɛba w’adwenem bere a wote nsɛmfua honam ani kokoram no. Nanso yɛwɔ anigye, efisɛ esiane aduruyɛ ho nyansahu a ɛkɔ anim nnɛ nti, ayaresa a etu mpɔn yiye wɔ hɔ a wɔde sa nyarewa a ɛtete saa. Sonidegib yɛ nnɛyi aduru a wɔde sa honam ani kokoram a ɛte saa ara, titiriw `Basal Cell Carcinoma`. Enti ɛnnɛ, momma yɛnka saa aduru yi ho asɛm wɔ nsɛm a ɛnyɛ den mu, sɛnea wɔde di dwuma, nea ɛsɛ sɛ yɛhwɛ yiye wɔ ho, ne nea efi mu ba nyinaa.
Aduru bɛn na Sonidegib yɛ?
Sɛ yɛbɛka no tiawa a, eyi yɛ aduru bi a wɔfrɛ no "targeted therapy." Eyi kyerɛ sɛ saa aduru yi de n’ani si kokoram nkwammoaa nkutoo so na esiw wɔn nyin ano, a ɛnsɛe nkwammoaa a wɔwɔ apɔwmuden. Mpɛn pii no wubehu eyi wɔ gua so wɔ edin Odomzo ase. Wɔde di dwuma titiriw de siw honam ani kokoram bi a wɔfrɛ no `Basal Cell Carcinoma' ano.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru
Ansa na wubefi saa ayaresa yi ase no, ɛho hia yiye sɛ wobɔ wo duruyɛfo amanneɛ pefee wɔ nea edidi so yi ho:
- Sɛ́ ebia woanya ntini mu yare biara pɛn.
- Sɛ́ ebia aduru Sonidegib ho adwenemhaw bi wɔ hɔ, anaasɛ aduru foforo biara, aduan, anaa aduru a wɔde yɛ ade ho.
- Sɛ worebɔ mmɔden sɛ wubenyinsɛn, anaasɛ worenyinsɛn mprempren a, eyi yɛ ade a ɛsɛ sɛ woka ho asɛm. Eyi yɛ asɛm a ɛho hia paa.
- Sɛ woyɛ ɛna a ɔma nufu a, yɛsrɛ sɛ bɔ yɛn amanneɛ nso.
Ɔkwan bɛn so ankasa na mede saa aduru yi di dwuma?
Sɛnea ɛbɛyɛ na woanya aduru yi so mfaso kɛse no, ɛho hia sɛ wode di dwuma sɛnea wɔakyerɛ no.
- Ɛsɛ sɛ wɔde nsu kuruwa mene saa aduru yi nyinaa .
- Mmu, nbubu, anaa nwe saa capsule yi da. Saa a wobɛyɛ no betumi aka sɛnea aduru no yɛ adwuma yiye.
- Ɛsɛ sɛ wɔfa eyi bere a yafunu da mpan . Ɛne sɛ, dɔnhwerew biako ansa na wɔadidi anaa nnɔnhwerew abien wɔ adidi akyi. Mfa eyi nka aduan ho.
- Ade foforo a ɛho hia ne sɛ wobɛkwati sɛ wobɛnom saa aduru yi ne bobe aba nsu.
- Fa w’aduru no da biara, sɛnea wɔakyerɛw ama wo no pɛpɛɛpɛ, bere a wo duruyɛfo bɛkyerɛw ama wo no. Mma nnyae w’aduru nom a wo duruyɛfo nka ho afotu.
- Sɛ wɔkyerɛw saa aduru yi ma wo a, wo nsa bɛka nsɛm titiriw kratasin (MedGuide) a ɛfa ho. Ɛho hia sɛ wokenkan na wote ase yiye bere biara.
Sɛ wopa nnuru dodow bi mpofirim a, mma wo ho nnyɛ wo hu. Wo werɛ mfi dodow a woayera no na fa dodow a edi hɔ no sɛnea wotaa yɛ no da a edi hɔ no wɔ bere a wɔahyɛ no mu. Mfa nnuru abien prɛko pɛ da esiane sɛ wo werɛ afi kɛkɛ nti.
Na sɛ menom nsa pii nso ɛ?
Sɛ wususuw sɛ woanom nnuru pii a, frɛ National Poisons Information Center a ɛwɔ Colombo National Hospital no ntɛm ara, anaa kɔ Emergency Treatment Unit (ETU) a ɛwɔ ayaresabea a ɛbɛn wo no.
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom nnuru no
Hwɛ saa nsɛntitiriw yi so titiriw na ama woanya ahobammɔ ne sɛnea w’ayaresa no bɛyɛ yiye bere a worenom aduru yi no.
- Nyinsɛn ne nufu a wɔde ma (ma mmea): Eyi ne ade a ɛho hia sen biara. Nnyinsɛn esiane biribiara nti bere a worenom aduru yi no. Afei nso, ɛsɛ sɛ wokwati sɛ wubenyinsɛn asram 20 bere a woagyae aduru no akyi . Saa aduru yi betumi ama awo mu dɛmdi a emu yɛ den anaa owu mpo aba akokoaa a ɔhyɛ yafunu mu. Ɛsɛ sɛ woyɛ nhwehwɛmu de hwɛ sɛ wunnyinsɛn ansa na woafi aduru no ase. Sɛ woyɛ ɛna a ɔma nufu a, mma nufu bere a worenom aduru no ne asram 20 bere a woagyae aduru no akyi.
- Wɔ mmarima a wɔpɛ sɛ wɔwo abofra no fam no: Kwati sɛ wobɛwo abofra bere a worenom saa aduru yi ne asram 8 bere a woagyae no. Sɛ wo ne obi da wɔ saa bere yi mu a , ɛsɛ sɛ wode latex kɔndɔm di dwuma. Eyi ho hia sɛ wɔayɛ wo vasectomy mpo a. Sɛ wo hokafo nyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Afei nso, kwati mmadwoa a wode bɛma bere a worenom saa aduru yi ne asram 8 bere a woagyae no.
- Mogya a Wɔde Ma: Mfa mogya mma bere a worenom aduru no ne asram 20 bere a woawie ayaresa no. Sɛ wɔde mogya no ma ɔbea a onyinsɛn a, ebia obenya saa aduru yi.
- Aduruyɛ mu nhwehwɛmu: Mpɛn pii no, wo duruyɛfo bɛhyɛ sɛ wɔmfa mogya nyɛ adwuma de hwɛ sɛnea aduru no renya wo nipadua so nkɛntɛnso bere a worenom saa aduru yi. Hwɛ hu sɛ wobɛyɛ saa sɔhwɛ ahorow yi daa.
Nsunsuanso bɔne a ebetumi aba esiane nnuru nti
Te sɛ aduru biara no, Sonidegib betumi de nsunsuanso bɔne bi aba. Eyinom bi betumi ayɛ aniberesɛm, enti ɛho hia sɛ wohu.
| Nsunsuanso bɔne | Nkyerɛmu |
|---|---|
| Nneɛma a ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara | |
| Ntini a asɛe ho sɛnkyerɛnne | Nsu a ɛyɛ sum, ɛyɛ den sɛ wobɛtow anaasɛ nsakrae a ɛba nsu dodow mu, ɔbrɛ anaa ɔbrɛ a ɛyɛ soronko, ntini mu yaw, anaa akyi/nan mu yaw. |
| Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo sɛ ɛkɔ so anaasɛ ɛhaw adwene a | |
| Nnuan a wɔyam no mu haw ahorow | Atiridiinini, akisikuru/fefe, yafunu mu yaw, aduan ho akɔnnɔ a ɛyera |
| Nsakrae afoforo a ɛba nipadua no mu | Nwi a ɛtɔ, mu duru a ɛso tew, dɛ a ɛsakra, ɛyaw, tiyɛ, ɔbrɛ |
Sɛ wunya sɛnkyerɛnne foforo biara a ɛyɛ soronko a wɔanka ho asɛm wɔ saa nsɛm yi mu a, wo ne wo duruyɛfo nkasa mfa ho nso.
Nnuru afoforo a ebetumi ne saa aduru yi adi nkitaho (Drug Interactions) .
‘Nnuru a ɛne ne ho di nkitaho’ ne bere a aduru biako a yɛnom no nya aduru foforo a yɛnom no dwumadi so nkɛntɛnso. Enti, ɛho hia paa sɛ woka nnuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo. Nnuru a ebetumi ne Sonidegib adi nkitaho no bi wɔ ase ha.
- Nnuru bi a wɔde sa fungal yare (e.g. ketoconazole, itraconazole, fluconazole) .
- Nnuru bi a wɔde sa akisikuru (e.g. carbamazepine, phenytoin) .
- Nnuru te sɛ atazanavir ne saquinavir
- Nnuru a ekum ɔyare mmoawa te sɛ erythromycin ne telithromycin
- Rifampin, rifabutin a wɔde hyɛ nipadua mu
- Nnuru a wɔde siw yafunu mu acid ano (e.g. omeprazole, famotidine) .
- Nneɛma a wɔde nhabannuru yɛ te sɛ St. John’s Wort
Saa list yi nwie pɛyɛ. Enti, ka nnuru, vitamin, anaa aduru biara a wonom ho asɛm kyerɛ wo duruyɛfo. Afei nso, sɛ wonom sigaret anaa wonom nsa a, mma wo werɛ mmfi sɛ wobɛka akyerɛ wo duruyɛfo.
Nkrasɛm a Wɔde Kɔ Fie
- Sonidegib yɛ aduru pɔtee bi a wɔde asi wɔn ani so a wɔde sa honam ani kokoram. Wɔakyerɛw saa aduru yi ama wo nkutoo na ɛnsɛ sɛ wɔde ma afoforo.
- Kwati sɛ wubenyinsɛn bere a worenom aduru yi ne asram 20 bere a woagyae no. Ɛsɛ sɛ mmarima kwati sɛ wɔbɛwo mma asram 8 bere a wɔagyae aduru no akyi. Eyi ho hia paa.
- Fa aduru no bere nyinaa bere a wo yafunu da mpan . Mmu, nbubu, anaa nwe capsules no.
- Sɛ wuhu sɛnkyerɛnne ahorow te sɛ ntini mu yaw anaa nsu a ɛyɛ tumm a, ka kyerɛ wo duruyɛfo ntɛm ara .
- Ka nnuru afoforo a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo. Sɛ wowɔ nsɛmmisa bi a, ntwentwɛn wo nan ase sɛ wubebisa wo duruyɛfo.
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