Nea ɛsɛ sɛ wuhu fa ‘Statins’ ho de siw srade ano

So wo mogya mu nhwehwɛmu a etwa to no kyerɛe sɛ wo srade dodow kɔ soro kakra? So wotee ehu nka kakra na wohaw wo ho bere a wuhui sɛ wo "srade bɔne" anaa LDL dodow nso dɔɔso no? Sɛ saa a, ebia wo duruyɛfo akyerɛ wo sɛ fi ase nom aduru bi a wɔfrɛ no ‘Statin’. Enti ɛnnɛ, momma yɛnka ‘Statins’ ho asɛm tiawa koraa, a ɛho hia nnipa pii.

Okay, dɛn ne saa ‘Statins’ yi?

Sɛ yɛbɛka no tiawa a, ‘Statins’ yɛ nnuru bi a nnuruyɛfo kyerɛw ma sɛ ɛbɛma srade a ɛwɔ wo mogya mu no so atew, titiriw srade "bɔne" no.

Sɛ yɛka srade ho asɛm a, bere nyinaa yɛte ahorow abien ho asɛm, ɛnte saa?

1. LDL (Low-Density Lipoprotein): Eyi ne nea yɛfrɛ no srade “bɔne” . Fa wo mogya ntini no sɛ paipu a ɛde nsu kɔ. Nea LDL srade yi yɛ ne sɛ ɛde te sɛ srade a ɛyɛ fĩ gu saa paipu no mu, na ɛma ɔkwan a mogya fa so no so tew nkakrankakra. ‘Statin’ ahorow bi betumi atew srade bɔne yi so 50% anaa nea ɛboro saa.

2. HDL (High-Density Lipoprotein): Eyi ne nea yɛfrɛ no srade "pa" . Ɛfa srade bɔne a ayɛ kɛse wɔ ntini ahorow no mu na ɛde kɔ mmerɛbo no mu ma woyi fi nipadua no mu. Ɛte sɛ obi a ɔboaboa nwura ano.

Ɛnyɛ sɛ statin tew LDL srade bɔne so nko, na mmom ɛboa ma triglycerides, srade foforo a ɛwɔ mogya mu no so tew, na ɛma HDL srade pa dodow kɔ soro kakra.

Wɔtaa kyerɛw nnuru yi sɛ wɔnnom pɛnkoro da biara, bere koro mu. Statin ahorow bi yɛ adwuma yiye bere a wɔnom no anadwo no. Nea enti a ɛte saa ne sɛ yɛn nipadua no ma srade pii ba anadwo. Nanso, statin foforo bi yɛ adwuma yiye saa ara bere a wɔnom no da no mu bere biara no. Wo duruyɛfo bɛkyerɛkyerɛ eyi mu akyerɛ wo.

Ɔkwan bɛn so na saa aduru yi yɛ adwuma wɔ nipadua no mu?

Eyi yɛ asɛm a ɛyɛ anigye yiye. Fa no sɛ wo mmerɛbo ne adwumayɛbea titiriw a wɔyɛ srade. Nokwarem no, srade a yɛn nipadua hia no mu 75% na ɛba yɛn mmerɛbo mu. Nea aka no fi aduan a yedi mu.

Enti, mmerɛbo no wɔ enzyme bi a ɛho hia ma saa srade a wɔyɛ yi. Wɔfrɛ no `HMG-CoA reductase`. `Statin` aduru no yɛ adwuma te sɛ ɔpon ano hwɛfo, na esiw `HMG-CoA reductase` enzyme no kwan sɛ ɛnkɔ mmerɛbo no mu. Afei mmerɛbo no hwere ade a wɔde yɛ srade a ehia na ama ayɛ srade. Ne saa nti, srade dodow a mmerɛbo no yɛ no so tew kɛse. So wote ase?

Dɛn nti na yehia ‘Statins’?

Nea enti titiriw ne sɛ wɔbɛtew asiane a ɛwɔ hɔ sɛ obi benya komayare ne akisikuru no so.

Sɛnea madi kan aka no, sɛ srade bɔne kɔ soro wɔ mogya no mu a, ɛkɔhyɛ mogya ntini no afasu so. Wɔ nnuruyɛ mu no, yɛfrɛ eyi ‘Atherosclerosis’ . Wɔfrɛ srade a ɛboaboa ano wɔ saa kwan yi so no ‘plaque’. Eyi ma baabi a ɛwɔ mogya ntini no mu no so tew na esiw mogya no kwan.

Susuw nea ɛbɛba sɛ ntini bi a ɛde mogya kɔ koma no mu no siw saa kwan yi so hwɛ? Koma no nnya mframa pa ne aduannuru a ehia. Ɛno ma obi nya komayare. Na sɛ saa ‘akyi’ yi pae wɔ ntini bi a ɛde mogya kɔ amemene no mu mu na mogya a ɛtɔ gu nipadua no mu ba a, ɛde akisikuru ba.

Statin brɛ mogya mu srade ase, na ɛtew asiane a ɛwɔ tebea horow a asiane wom yi mu no so kɛse.

Dɛn ne ‘statins’ ahorow a wɔtaa de di dwuma?

‘Statins’ ahorow pii wɔ hɔ. Wo duruyɛfo bɛkyerɛw nea ɛfata wo kɛse, na wasusuw w’akwahosan tebea, srade dodow, ne nneɛma afoforo ho.

Ɛtɔ da bi a ‘statin’ bi ba wɔ aduru koro no ara mu ne aduru foforo. Sɛ nhwɛso no, aduru bi a wɔfrɛ no ezetimibe a wɔde simvastatin ka ho.

Hena na wɔkamfo kyerɛ sɛ ɔmfa ‘Statins’?

Oduruyɛfo bi begyina asiane a ɛwɔ hɔ sɛ wubenya komayare nyinaa so akyerɛw statin ama wo. Eyi gyina nneɛma pii so, a nea ɛka ho ne mfe a woadi, wo bɔbeasu, abusua abakɔsɛm, ne sɛ ebia wonom sigaret. Wɔtaa kamfo statin kyerɛ nnipa a wodi so yi:

• Wɔ wɔn a wontumi ntew wɔn srade dodow so (titiriw LDL dodow a ɛboro 190 mg/dL) ɛmfa ho sɛ wodi aduan na wɔteɛteɛ wɔn apɔw mu no fam no .
• Wɔ nnipa a wɔwɔ asikreyare ne wɔn a wɔadi fi mfe 40-75 fam, a LDL srade dodow boro 70 mg/dL.
• Wɔn a wɔanya komayare, akisikuru, anaa ntini a ɛwɔ akyi (PAD) dedaw no fam no .
• Wɔ nnipa a wɔadi mfe 40-75 a LDL dodow boro 70 mg/dL, a asiane kɛse wom sɛ wobenya komayare fam no.
• Sɛ obi a ɔwɔ abusua no mu (awofo, anuanom) anya komayare wɔ ne mmofraase na ne srade dɔɔso a.

So nsunsuanso bɔne bi wɔ eyi mu?

Eyi yɛ ɔhaw ma nnipa pii. Ɛyɛ nokware sɛ, te sɛ nnuru biara no, statin betumi anya nkɛntɛnso bɔne. Nanso nea ɛho hia ne sɛ nnipa dodow no ara nnya ɔhaw biara. Nsunsuanso nketenkete a ɛba mpo befi hɔ bere a wɔtoa aduru no so no.

Nea ɛho hia: Sɛ wuhu ɔhaw biara a, w’ankasa nnyae w’aduru nom da. Ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wo ne wo duruyɛfo bɛkasa afa ho. Ebia wubetumi adi ɔhaw no ho dwuma denam statin ko a worenom a wobɛsesa anaasɛ wobɛsakra dodow a wode di dwuma no so.

So nnipa bi wɔ hɔ a ɛnsɛ sɛ wɔnom statin?

Aane. Wɔnkamfo statin nkyerɛ mmea a wɔyem, ɛnanom a wɔma nufu, ne nnipa a wɔwɔ mmerɛbo mu nyarewa bi a emu yɛ den. Ɛsɛ sɛ woka nnuru foforo biara a worenom nso kyerɛ wo duruyɛfo. Nnuaba mu nsu, titiriw bobe ne granate nsu betumi ne statin ahorow bi adi nkitaho, enti bisa wo duruyɛfo no ɛno nso ho asɛm.

Sɛ wugyae aduru no nom a, dɛn na ɛba?

Sɛ wugyae statin nom pɛ a, wo srade a ɛwɔ wo mu no san kɔ soro kodu baabi a na ɛwɔ no. Ɛno kyerɛ sɛ asiane a ɛwɔ hɔ sɛ wubenya komayare ne akisikuru no san kɔ soro. Enti mpɛn pii no ɛyɛ nkwa nna nyinaa aduru.

Bere a ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn ntɛm ara

Sɛ wuhu sɛnkyerɛnne ahorow a edidi so yi mu biara bere a worenom statin a, hwehwɛ aduruyɛfo afotu ntɛm ara.

• Sɛ wote nka sɛ wuntumi nnyina ano a, ɛyaw a emu yɛ den anaa mmerɛwyɛ wɔ wo ntini anaa wo nkwaa mu.
• Sɛ wowɔ nipadua mu yaw a atiridii .
• Wo deɛSɛ w’ani anaa wo honam ani yɛ kɔkɔɔ (jaundice).
• Sɛ wo nsu dan kɔla tuntum te sɛ tii nhaban nsu a .

Wɔ tebea a ɛte saa mu no, ɛbɛyɛ papa sɛ wobɛkɔ ayaresabea Emergency Treatment Unit (ETU).