Ɛyɛ ade a ɛfata sɛ wobɛte ehu ne ehu nka kakra bere a wo anaa wo dɔfo bi fi ase sa kokoram no. Saa ehu no betumi ayɛ kɛse, titiriw bere a wote asɛmfua ‘chemotherapy’ no. Nanso mma wo ho nnsuro koraa. Sɛ ayaresa nhyehyɛe yi bɛyɛ yiye a, ɛsɛ sɛ yedi kan hu aduru yi ho nsɛm yiye. Afei yebetumi agyina akwantu yi ano yiye. Ɛnnɛ yɛreka aduru biako a ɛte saa a ɛko tia kokoram, Thioguanine (6-TG) ho asɛm.
Aduru bɛn na Thioguanine (6-TG) yɛ?
Sɛ yɛbɛka no tiawa a, Thioguanine yɛ aduru a ɛko tia kokoram . Nnuruyɛfo frɛ no ‘nnuru a wɔde sa yare’ aduru. Ne dwumadi titiriw ne sɛ ebesiw kokoram nkwammoaa a ɛpaapae ntɛmntɛm wɔ nipadua no mu no nyin na asɛe wɔn.
Wɔde saa aduru yi di dwuma titiriw de sa mogya mu kokoram ahorow bi , a ɛyɛ mogya mu nkwammoaa mu kokoram. Ɛtɔ da bi a, wo duruyɛfoɔ nso bɛtumi akyerɛw saa aduru yi ama tebea foforɔ. Enti sɛ wowɔ nsɛmmisa bi fa nea enti a wɔama wo saa aduru yi ho a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru
Ansa na wubefi Thioguanine ayaresa ase no, ɛho hia yiye sɛ wobɔ wo duruyɛfo amanneɛ wɔ w’akwahosan ho abakɔsɛm a edi mũ ho. Efisɛ ɛsɛ sɛ yɛhwɛ yiye paa bere a yɛde aduru yi redi dwuma wɔ akwahosan tebea horow bi ho no. Sɛ wowɔ nea edidi so yi bi a, hwɛ hu sɛ wobɛka ho asɛm akyerɛ yɛn.
| Akwahosan tebea/nokwasɛm | Dɛn nti na ɛsɛ sɛ wobɔ oduruyɛfo no amanneɛ? |
|---|---|
| Mprempren nyarewa (titiriw nea mmoawa de ba te sɛ akokɔsrade ne akisikuru) . | Esiane sɛ saa aduru yi ma nipadua no tumi a ɛko tia nyarewa no so tew nti, ɔyare mmoawa a ɛwɔ hɔ dedaw no betumi asɛe kɛse. |
| Mmɛn mu yare | Esiane sɛ mmerɛbo na ɛyɛ saa aduru yi ho adwuma nti, ebetumi anya nkɛntɛnso bɔne wɔ mmerɛbo mu yare mu. |
| Mogya mu nkwammoaa dodow a ɛso tew (mogya mu nkwammoaa fitaa, mogya mu nkwammoaa kɔkɔɔ, mogya mu nkwammoaa kɔkɔɔ) . | Thioguanine betumi atew mogya mu nkwammoaa a wɔyɛ so bio, na sɛ wo mogya mu nkwammoaa dodow sua dedaw a, ebetumi ayɛ asiane. |
| TPMT a enni nipadua mu (Thiopurine methyltransferase a enni nipadua mu) . | Eyi yɛ awosu mu tebea. Ebia nnipa a wonni saa enzyme yi benya Thioguanine a ɛdɔɔso wɔ wɔn nipadua mu, na ama nea efi mu ba no ayɛ kɛse. |
| Nneɛma a ɛma obi ho yɛ no hyew | Ɛho hia sɛ wobɔ wo duruyɛfo amanneɛ sɛ wowɔ Thioguanine anaa nnuru anaa nnuan afoforo ho akisikuru bi a. |
| Mmɔden a wɔbɔ sɛ wobenyinsɛn, nyinsɛn, anaa nufu a wɔde ma | Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu no kɛse , enti ɛho hia sɛ woka ho asɛm. |
Ɔkwan bɛn so na ɛsɛ sɛ mede aduru no di dwuma?
Ɔkwan a wɔfa so de saa aduru yi di dwuma no yɛ mmerɛw yiye, nanso ɛho hia yiye.
- Fa nsu kuruwa mene aduru no , sɛnea wɔakyerɛ wɔ wo nnuru a wɔakyerɛw ama wo no mu no.
- Nom w’aduru no da biara, sɛnea wo duruyɛfo ka kyerɛ wo pɛpɛɛpɛ, bere a wɔaka akyerɛ wo no. Mma nntwa bere a wɔahyɛ sɛ wobɛkɔ no so.
- Nnyae nnuru no nom anaasɛ nnsesa dodow no esiane biribiara nti a wo duruyɛfo mfi wo nyansa.
- Sɛ wode saa aduru yi rema mmofra a, wo ne wo mmofra oduruyɛfo nka ho asɛm na di wɔn akwankyerɛ akyi.
Ahwɛyiye: Sɛ wususuw sɛ woanom nnuru pii asen nea wɔakyerɛw ama wo a, ntwentwɛn wo nan ase. Ntɛm ara frɛ National Poisons Information Center a ɛwɔ Colombo National Hospital anaa kɔ Emergency Department (ETU) a ɛwɔ ayaresabea a ɛbɛn wo no.
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wopa dose bi a, mma ɛnhaw wo. Twa dose a woayera no so na fa dose a edi hɔ no wɔ bere a wɔahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da.Ɛno kyerɛ sɛ nnom nnuru mmɔho abien mfa nsiesie nea wo werɛ afi no. Sɛ wofe bere a woanom aduru no awie a, bisa wo duruyɛfo ma ɔmma no afotu wɔ nea ɛsɛ sɛ woyɛ akyi.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Ɛho hia yiye sɛ wobɛka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo, a nnuru a wɔkyerɛw ma wo, nnuru a wɔtɔn, vitamin, nhabannuru, ne nnuru a wɔde ka ho mpo ka ho. Nnuru bi betumi ne Thioguanine adi nkitaho na ama nea efi mu ba no ayɛ kɛse anaasɛ ɛbɛsakra sɛnea ɛyɛ adwuma yiye.
Hwɛ yiye titiriw wɔ nnuru a edidi so yi ho:
- Busulfan (aduru foforo a ekum kokoram) .
- Nnuru a ɛmma mogya ntumi nkɔ (e.g. Warfarin) .
- Nnuru a ɛma mogya mu nkwammoaa dodow kɔ soro (e.g. filgrastim) .
- Nnuru te sɛ Mesalamine, Olsalazine, Sulfasalazine, Balsalazide
- Vaccines a ɛyɛ ɔkwan biara so
Kɔkɔbɔ titiriw: Mfa nnuru a wɔde kum ɛyaw a wɔtɔn te sɛ aspirin, acetaminophen, ne ibuprofen a wonkɔ wo duruyɛfo nkyɛn. Saa nnuru yi tumi siw yare no ho sɛnkyerɛnne te sɛ atiridiinini ano. Ɛho hia sɛ wuhu atiridii ntɛm, a ebetumi ayɛ ɔyare no ho sɛnkyerɛnne ntɛm, bere a worenom Thioguanine no.
Nneɛma a ɛsɛ sɛ wususuw ho bere a wɔreyɛ ayaresa no
Esiane sɛ nnuru a wɔde sa kokoram no ka kokoram nkwammoaa ne nkwammoaa a wɔwɔ apɔwmuden nyinaa nti, ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo ho nyɛ wo dɛ na woayɛ mmerɛw. Nanso, nnyae ayaresa kosi sɛ wo duruyɛfo bɛka akyerɛ wo esiane saa ɔhaw ahorow yi nti.
- Bɔ wo ho ban fi nyarewa ho: Saa aduru yi brɛ wo nipadua no mu tumi a ɛko tia nyarewa no ase, enti ɛda adi sɛ wobɛyare. Enti, kwati sɛ wobɛkɔ mmeae a nnipa ahyɛ hɔ ma na wo ne ayarefo (wɔn a wɔwɔ atiridii anaa atiridiinini) adi nkitaho sɛnea wubetumi biara. Sɛ wuhu sɛnkyerɛnne ahorow te sɛ atiridiinini, atiridiinini, menewa mu yaw, anaa nipadua mu yaw a , nnyɛ wo ho aduru na ka kyerɛ wo duruyɛfo ntɛm ara.
- Hwɛ yiye wɔ mogya a ɛbɛtɔ ho: Asiane a ɛwɔ hɔ sɛ mogya bɛtɔ no betumi ayɛ kɛse. Enti, brush wo sẽ brɛoo. Mfa brɔs a ɛyɛ den nni dwuma. Hwɛ sɛ akuru anaa nsensanee kɔkɔɔ nketenkete bi wɔ honam ani anaa. Sɛ wuhu biribi a ɛte saa a, ka kyerɛ wo duruyɛfo.
- Kwati nyinsɛn: Eyi ho hia paa. Kwati sɛ wubenyinsɛn koraa bere a worenom aduru yi no. Afei nso, kwati sɛ wobɛma nufu bere a worenom aduru yi. Bisa wo duruyɛfo ma ɔmma no eyi ho nsɛm pii.
Dɛn ne nneɛma bɔne a ɛtaa ba?
Te sɛ aduru biara no, Thioguanine betumi de ɔhaw ahorow aba. Nanso ɛnyɛ obiara na onya bi. Ebi abu so paa, na ebi nso ho yɛ na paa. Nea ɛho hia ne sɛ wubehu nea efi mu ba ne nea sɛ ɛba a, ɛsɛ sɛ woyɛ.
| Thioguanine (6-TG) ho nsunsuanso bɔne | |
|---|---|
| 🚨 Nsunsuansoɔ bɔne a ɛhia sɛ wɔkɔ ayaresabea ntɛm ara | |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ obi ho yɛ no yaw | Wora mu akisikuru, ɛyaw, anim, anofafa, tɛkrɛma a ɛho ahonhon, ɛyɛ den sɛ wobɛhome. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare mmoawa | Atiridiinini, atiridiinini, ɔfe, menewam yaw, ɛyaw bere a woretow nsu. |
| Mogya a ɛretu ho sɛnkyerɛnne | Honam ani akisikuru a wontumi nkyerɛkyerɛ mu, nsensanee kɔkɔɔ a ɛwɔ honam ani, nsu tuntum, ne mogya a ɛwɔ nsu mu. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ mogya a ɛtɔ mogya mu | Ɔbrɛ a ɛyɛ soronko, ɔbrɛ, adwenemhaw, aniwa bruu. |
| mmerɛbo mu haw ahorow | Ɛyaw a ɛba yafunu no nifa so atifi, aniwa anaa honam ani yɛ kɔkɔɔ (jaundice). |
| Nsɛnkyerɛnne afoforo a anibere wom | Ano mu akuru, nansoaa, nan anaa yafunu a ɛho ahonhon, mu duru a ɛkɔ soro mpofirim. |
| 🙂 Nsunsuansoɔ bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfoɔ sɛ ɛkɔ so | |
| Nnuan a wɔyam no mu haw ahorow | Atiridiinini, aduan ho akɔnnɔ a ɛyera, akisikuru, ɔfe. |
Ɔkwan bɛn so na wɔkora nnuru so yiye?
- Fa sie baabi a ahobammɔ wɔ a mmofra ntumi nkɔ hɔ.
- Fa sie baabi a ɛhɔ yɛ kusuu wɔ dan mu hyew (ɛyɛ digrii Celsius 15 kosi 25).
- Bɔ ho ban fi nsu ho. Enti fa aduru toa no to mu denneennen.
- Tow aduru biara a atwam bere a ne bere atwam no gu.
Nkrasɛm a Wɔde Kɔ Fie
- Thioguanine yɛ nnuru a wɔde sa kokoram te sɛ mogya mu kokoram.
- Fa w’aduru no sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ bere nyinaa, wɔ bere a ɛfata mu.
- Ka nnuru afoforo, vitamin, ne nnuru a wɔde di dwuma wɔ amanne kwan so a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo.
- Sɛ wuhu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ ɔyare mmoawa anaa mogya retu, te sɛ atiridiinini, akisikuru, anaa akuru a, bɔ wo duruyɛfo amanneɛ ntɛm ara.
- Kwati nyinsɛn ne nufu a wɔde ma koraa bere a worenom aduru yi no.
- Nnyae ayaresa anaasɛ ɛnsesa dodow a wɔde ma no da a wunni aduruyɛ mu afotu.
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