So woreda onyin ntɛm ho sɛnkyerɛnne nso adi? Momma yɛnka Werner Syndrome ho asɛm!

So wote nka sɛ wo ho yɛ fɛ sen wo mfe? Bere a ɛyɛ ade a ɛfata sɛ ɛtɔ mmere bi a wobɛte nka saa no, onyin ntɛm, anaasɛ nipadua no nyin ntɛmntɛm no betumi afi awosu mu tebea bi a ɛntaa nsi mu aba ankasa. Tebea a ɛte saa no biako ne Werner Syndrome. Momma yɛnka eyi ho asɛm nkɔ akyiri kakra nnɛ, efisɛ ɛho hia yiye sɛ yɛma yɛn ani da hɔ.

Dɛn ne Werner Syndrome?

Sɛ yɛbɛka no tiawa a, Werner Syndrome yɛ awosu mu yare a ɛntaa nsi a ɛma wo nipadua nyin ntɛmntɛm sen sɛnea na wohwɛ kwan. Nnipa binom frɛ no ‘mpanyimfo progeria’. Mpɛn pii no, sɛnkyerɛnne ahorow no nna adi kosi sɛ wubedu mmerantebere ne mmabaabere mu. Ɛno kyerɛ sɛ wubefi ase ahu nsonsonoe bere a wugyae nyin ntɛmntɛm te sɛ wo nnamfo no. Afei, wo mfe 20 mu no, wubefi ase ahu onyin ho sɛnkyerɛnne - ne, bere kɔ so no, nyarewa a ɛba bere a onyin ba.

Nanso eyi nyɛ ti nhwi a ɛyɛ fitaa ne honam ani a ɛyɛ mmerɛw kɛkɛ. Mpanyinyɛ nyɛ sɛnea obi bɛsakra ne ho ara kwa. Nnipa pii a wɔwɔ Werner Syndrome no nya nsɛnnennen a ɛde wɔn nkwa to asiane mu wɔ wɔn mfe 40 ne 50 mu.

Dɛn ne sɛnkyerɛnne ahorow yi?

Sɛ wowɔ Werner Syndrome a, yare no ho sɛnkyerɛnne no da adi kɛse bere a worenyin no. Ebia wubefi ase ahu onyin ho sɛnkyerɛnne ntɛm asen afoforo a wɔne wo bɔ tipɛn, wɔ wo mfe 20 mu. Wɔn mu bi ni:

Nsakrae a ɛba wɔ sɛnea obi te

• Nwi a ɛyɛ fitaa ne ti nhwi a ɛtɔ: Ɛnyɛ ti so nhwi nko na ɛka eyi ho, na mmom aniwa ne aniwa nhwi nso.
• Ɛnne a ɛreyɛ den anaasɛ ɛyɛ dede.
• Srade a ɛwɔ honam ani a ɛso tew: Eyi betumi ama honam ani ayɛ te sɛ nea ayɛ mmerɛw.
• Ntini a ɛyɛ mmerɛw.
• Nsõ a ɛporɔw ntɛm.
• Honam ani mmeae bi a ɛyɛ tuntum (hyperpigmentation) anaasɛ mmeae bi a ɛyɛ hare (hypopigmentation).
• Wora a ɛyɛ kɔkɔɔ esiane mogya ntini a atrɛw nti.
• Wora a ɛma ɛyɛ mmerɛw anaasɛ ɛyɛ den: Eyi te sɛ tebea bi a wɔfrɛ no scleroderma kakra.
• Anim a ɛyɛ pintinn na ɛhaw adwene.

Akwahosan ho haw afoforo a efi nipadua no mu

Sɛ wowɔ Werner Syndrome a, ɛnyɛ sɛ worehwɛ sɛ woabɔ akwakoraa kɛkɛ. Wo nipadua nyin ntɛmntɛm ankasa sen wo mfe ankasa. Eyi kyerɛ sɛ ebia wubenya akwahosan ho haw afoforo nso ntɛm sen sɛnea wohwɛ kwan. Eyinom bi ne:

• Asikreyare a ɛto so abien: Nokwarem no, nnipa 10 biara a wɔwɔ Werner Syndrome no mu bɛyɛ 7 nya asikreyare a ɛto so abien bere a wɔadi mfe 35 no.
• Hypogonadism (ntumi nyɛ adwuma wɔ awotwaa anaa awotwaa mu).
• Honam ani akisikuru.
• Osteoporosis (nnompe a ɛyɛ teateaa).
• Ntini mu ntini a ɛyɛ den.
• Aniwa a ɛyɛ mmerɛw anaasɛ aniwa a ɛyɛ mmerɛw.
• Koko mu yaw (angina).
• Koma mu ntini a ɛyɛ mmerɛw.
• Koma mu yareɛ `(koma mu yareɛ)`.

Kokoram ho asiane

Nnipa a wɔwɔ Werner Syndrome no wɔ asiane a ɛkɔ soro sɛ wobenya kokoram ahorow bi. Nhwɛsoɔ:

• Thyroid kokoram.
• Melanoma (honam ani kokoram).
• Osteosarcoma (nnompe mu kokoram).
• Ntini a ɛyɛ mmerɛw sarcoma.

Dɛn na ɛde Werner Syndrome ba?

Eyi yɛ awosu mu yare . Ɛne sɛ, nkwaadɔm mu nsakrae a ɛba yɛn awosu mu na ɛde ba. Werner Syndrome ba nnipa a wɔwɔ sintɔ abien wɔ WRN awosu mu abɔde mu. Mpɛn pii no, awosu mu nkwaadɔm abien a asɛe yi mu biako fi ɛna no hɔ na biako nso fi agya no hɔ.

Wobɛyɛ dɛn ahu eyi? (Nyare a Wɔahu) .

Wo duruyɛfo bɛhwehwɛ nneɛma bi a ɛbɛma wahu Werner Syndrome. Wobetumi nso ahyɛ sɛ wɔnyɛ sɔhwɛ ahorow yi:

• Awosu mu nhwehwɛmu: Hwɛ sɛ nsakrae bi aba awosu mu abɔde a ɛde Werner Syndrome ba no mu anaa.
• X-ray: Hwɛ sɛ nnompe mu nsakrae anaa akisikuru bi wɔ hɔ anaa.

Ɛtɔ mmere bi a nnuruyɛfo tumi hu Werner Syndrome bere a wɔadi mfe 15 pɛ. Nanso, wɔtaa hu yare no wɔ mfe 30 anaa 40 mu. Nea enti a ɛte saa ne sɛ yare no ho sɛnkyerɛnne pɔtee bi gye bere tenten saa ansa na ada adi.

Dɛn ne ayaresa ahorow no?

Wogyina sɛnkyerɛnne ahorow a ɛda adi so na ɛsa Werner Syndrome. Eyi kyerɛ sɛ ayaresa biako nyɛ adwuma mma obiara. Ebia nnuruyɛfo atitiriw pii bɛyɛ adwuma abom ayɛ w’ayaresa nhyehyɛe no ho nhyehyɛe. Nhwɛsoɔ:

• Endocrinologists (hormone ho abenfo).
• Aniwa ho animdefo ( aniwa ho animdefo).
• Nnompe ne nkwaa ho animdefo (nnompe ne nkwaa ho abenfo).

Ebia ayaresa a wɔde ma wo no bi ne:

• Asikreyare aduru: Hwɛ asikre dodow a ɛwɔ wo mogya mu no so.
• Ahwehwɛ anaa ahwehwɛ a wɔde hwɛ ade: Teɛ aniwa mu haw ahorow.
• Nnuru a wɔde sa komayare:Tew asiane a ɛwɔ hɔ sɛ nsɛnnennen bɛba no so denam ntini mu yare a wobɛhwɛ so no so.
• Oprehyɛn: Sɛ kokoram bi wɔ hɔ a, yi fi hɔ.

So wobetumi asiw Werner Syndrome ano?

Esiane sɛ eyi yɛ awosu mu tebea nti, awerɛhosɛm ne sɛ, wontumi nsiw Werner Syndrome ano.

Nanso, sɛ wo ne wo hokafo nyinaa wɔ awosu mu abɔde a ɛma tebea yi ba, na wopɛ sɛ wowo mma nso a, ebia wobɛpɛ sɛ wususuw ɔkwan bi a wɔfrɛ no preimplanttation genetic testing (PGT) ho. PGT yɛ awosu mu nhwehwɛmu ne in vitro fertilization (IVF) a wɔaka abom. Nea ɛka eyi ho ne sɛ wɔbɛsɔ nkwaboaa no ahwɛ ansa na wɔde ahyɛ awotwaa no mu na ama hokwan a ɛwɔ hɔ sɛ mmofra no benya awosu mu sintɔ ahorow yi afi awo mu no so atew. Nanso, eyinom yɛ akwan horow a ɛyɛ den kakra, enti ɛsɛ sɛ wosi gyinae wɔ aduruyɛ mu afotu nkutoo so.

Dɛn bio na wobɛpɛ sɛ wubisa wo duruyɛfo?

Sɛ wowɔ Werner Syndrome a, ɛho hia sɛ wubisa wo duruyɛfo nsɛm a wowɔ nyinaa. Sɛ nhwɛso no, wubetumi abisa nneɛma te sɛ:

• So ɛyɛ adwene pa sɛ mɛyɛ awosu mu nhwehwɛmu a ɛkyerɛ sɛ obi anya Werner Syndrome?
• Dɛn ne ayaresa a wobetumi apaw ama Werner Syndrome?
• Dɛn na ɛsɛ sɛ meyɛ na ama kokoram ho asiane a ɛwɔ hɔ no so atew?
• Nhwehwɛmu bɛn na ɛsɛ sɛ meyɛ na ama matumi asiw Werner Syndrome ho nsɛnnennen ano?
• Hokwan bɛn na ɛwɔ hɔ sɛ me mma benya Werner Syndrome afi me hɔ?
• Hokwan ahorow bɛn na ɛwɔ hɔ sɛ mɛwo abofra foforo a ɔwɔ Werner Syndrome?

Tebea afoforo bɛn na ɛwɔ sɛnkyerɛnne a ɛte saa ara?

Wɔ Werner Syndrome akyi no, tebea afoforo pii wɔ hɔ a ɛma obi tenten yɛ tiaa na onyin ntɛm. Eyinom bi ne:

• De Barsy yare a ɛma obi nya ɔyare no
• Gottron yare a ɛma obi nya ɔyare no
• Hutchinson-Gilford syndrome (eyi ne Progeria a ɛka mmofra nkumaa) .
• Mulvihill-Smith yare a ɛma obi nya ɔyare no
• Rothmund-Thomson yare a ɛma obi nya ɔyare no
• Ahum a ɛbɔ ho yare

Eyinom nyinaa yɛ tebea horow a ɛntaa nsi, enti ɛho hia yiye sɛ wubehu yare no pɛpɛɛpɛ.

Abakɔsɛm kakra a ɛfa Werner Syndrome ho ne sɛnea ɛtaa ba?

Oduruyɛfo bi a wɔfrɛ no Otto Werner na odii kan huu Werner Syndrome wɔ 1900 mfe no mfiase mu hɔ. Nsɛnkyerɛnne abien a odii kan huu wɔ ayarefo nkumaa mu ne ani a ɛyɛ mmerɛw ne honam ani nsensanee a ɛhyerɛn na ɛyɛ tuntum.

Eyi yɛ tebea a ɛntaa nsi koraa. Efi bere a wotintim yare no ho amanneɛbɔ a edi kan wɔ 1904 mu no, wɔabɔ nnipa bɛyɛ 800 pɛ ho amanneɛ wɔ aduruyɛ ho nsɛmma nhoma ahorow mu.

Wɔ United States no, abenfo bu akontaa sɛ ebia nnipa 200,000 biara mu biako wɔ Werner Syndrome. Wɔ wiase nyinaa no, nea ɛba no sua te sɛ ɔpepem biako biara mu biako.

Nanso, abu so kɛse wɔ Japan ne Sardinia mantam mu wɔ Italy. Ɛhɔ no, nnipa 30,000 anaa 50,000 biara mu bɛyɛ biako wɔ saa yare yi. Nea enti a ɛte saa ne sɛ nnipa pii a wɔwɔ saa mmeae no anya awosu mu nsakrae bi a esii awo ntoatoaso pii a atwam ni no.

Sɛ wuhu sɛ wo anaa wo dɔfo bi wɔ Werner Syndrome a, ebetumi ayɛ den. Ebetumi ayɛ abasamtu efisɛ aduru biara nni hɔ. Nanso, ayaresa betumi atew asiane a ɛwɔ ɔhaw ahorow a ɛde nkwa to asiane mu no so.

Awiei koraa no, nkrasɛm a wɔde kɔ fie no

Werner Syndrome yɛ tebea a emu yɛ den ankasa, nanso kae sɛ ɛnyɛ wo nkutoo na wowɔ hɔ.

• Nya ayaresa ne afotu a ɛfata: Eyi bɛboa wo ma woadi wo yare no ho sɛnkyerɛnne ahorow ho dwuma na ama w’asetra atu mpɔn.
• Di asetra a ahoɔden wom akyi: Da sɛnea ɛsɛ, di nnuan a ahoɔden wom, fa aduru a ɛbɔ wo ho ban fi owia ho di dwuma bere a worekɔ owia mu, na bɔ mmɔden sɛ wobɛtew adwennwen so. Saa nneɛma yi bɛboa wo ma woanya apɔwmuden.
• Hwehwɛ mmoa: Bisa w’aduruyɛfo kuw no mmoa akuw ho asɛm. Ebia wonte nhyɛso kɛse nka mprempren, nanso fa saa nsɛm no to wo nsam. Ebia ɛbɛboa daakye.

Nyarewa a ɛntaa nsi te sɛ eyi a wobɛtra ase no nyɛ mmerɛw. Nanso sɛ wunya nimdeɛ a ɛfata, mmoa, ne adwempa a, wubenya ahoɔden a wode bɛfa saa akwantu yi mu.

` Werner syndrome, awosu mu nyarewa, onyin ntɛm, mpanyimfo progeria, WRN awosu mu nkwaadɔm, akwahosan ho haw, kokoram ho asiane