So woahu baabi a ɛyɛ kɔkɔɔ-biribiri wɔ wo ba anaa w’ankasa wo nipadua so pɛn? Ebia wode wo nsateaa hwirew baabi no brɛoo kɛkɛ, na mpofirim ara baabi no danee kɔkɔɔ, fii ase yɛɛ wo yaw, na akisikuru ketewaa bi puei wɔ soro. Sɛ osuahu yi yɛ nea wunim a, ɛho hia yiye sɛ wuhu tebea a yɛreka ho asɛm nnɛ no.
Sɛ yɛbɛka no tiawa a, dɛn ne Urticaria Pigmentosa?
Urticaria Pigmentosa yɛ akisikuru bi a ɛba honam ani. Wɔtaa hu no wɔ mmofra nkumaa ne mpanyimfo nkumaa mu. Ɛyɛ tebea bi a wɔfrɛ no `mastocytosis' bi ankasa.
Afei ebia woresusuw nea `mastocytosis` yɛ ho. Ɛyɛ mmerɛw yiye. ``mast cells`` yɛ nkwammoaa soronko bi a ɛwɔ yɛn nipadua mu nipadua mu ahoɔden a ɛko tia nyarewa no mu. Wɔte sɛ amu no ho awɛmfo. Sɛ biribi nti saa mast cells yi boaboa ano boro so wɔ honam ani fã biako a, yɛfrɛ no Urticaria Pigmentosa. Nanso, ɛnyɛ honam ani nko na saa mast cells yi tumi boaboa ano, na mmom ɛtɔ mmere bi a ɛwɔ akwaa afoforo te sɛ nnompe ne dwensɔtwaa mu. Afei ɛdan tebea bi a wɔfrɛ no ``systemic mastocytosis``. Nanso mma ɛnhaw wo, mpɛn pii no, Urticaria Pigmentosa a ɛwɔ mmofra mu no yɛ honam ani nkutoo.
Wɔ saa yare yi mu no, sɛ nsensanee bruu bi pue wɔ honam ani a, ɛyɛ kɔkɔɔ, ɛho ahonhon, ɛyɛ yaw, na ɛkɔ soro te sɛ nea kar abɔ no. Wɔ aduruyɛ mu no, wɔfrɛ saa sɛnkyerɛnne yi ``Darier sɛnkyerɛnne.''
Dɛn nti na biribi a ɛte sɛɛ si?
Ade titiriw nti a eyi ba ne ``mast cells`` a yɛadi kan aka ho asɛm no. Eyinom yɛ mogya mu nkwammoaa fitaa bi a wɔyɛ wɔ yɛn nnompe mu. Saa nkwammoaa yi wɔ yɛn nipadua nyinaa mu, titiriw baabi a yɛne wiase a ɛwɔ akyi te sɛ honam ani, ahurututu, ne dwensɔtwaa di nkitaho. Sɛ biribi te sɛ ɔyare mmoawa hyɛn nipadua no mu a, saa mast cells yi yi nnuru bi a wɔfrɛ no ``histamine`` ma ɛboa ma nipadua no bɔ ho ban.
Urticaria Pigmentosa fi awosu mu nsakrae a ɛma saa mast cells yi boaboa ano boro so wɔ honam ani. Mpɛn pii no, saa awosu mu nsakrae yi ba bere a abofra da so ara wɔ awotwaa mu no. Nanso, ɛnyɛ biribi a wonya fi awofo hɔ ma mmofra . Wonnya nhuu nea ɛde saa nkwaadɔm mu nsakrae yi ba ankasa.
Sɛ mpanyimfo nya saa tebea yi a, ebetumi ayɛ den kakra. Wɔfrɛ no `indolent nhyehyɛe mu mastocytosis`. Wɔ eyi mu no, mast cells boaboa ano wɔ mmeae te sɛ nnompe mu ntini de ka honam ani. Ɛntaa mma sɛ saa tebea yi betumi abɛyɛ kokoram tebea a wɔfrɛ no `mast cell leukemia`. Nanso bio, eyinom yɛ nneɛma a wɔntaa nhu koraa . Urticaria Pigmentosa a ɛba mmofra mu no mu 99% nyɛ den saa.
Dɛn ne yare yi ho sɛnkyerɛnne?
Nsɛnkyerɛnne titiriw a ɛda adi kɛse ne `Darier sɛnkyerɛnne` a yɛkaa ho asɛm no. Ɛne sɛ, nsensanee a ɛyɛ bruu no yɛ kɔkɔɔ na ɛyɛ yaw bere a wɔde petepete so no. Nea ɛka ho no, nnipa binom nso betumi anya yare no ho sɛnkyerɛnne a edidi so yi.
| Nsɛnkyerɛnne a ɛkyerɛ | Nkyerɛkyerɛmu a ɛnyɛ den |
|---|---|
| Koma a ɛbɔ denneennen | Koma bɔ kɔ soro te sɛ nea wote ehu nka. |
| Ɔyare a ɛma obi dwensɔ (yafunu mu yaw) . | Ebetumi afi mast cell a ɛyɛ adwuma wɔ aduan mu no mu aba. |
| Flushing a wɔde wɔn ho hyɛ mu | Anim ne nipadua no atifi a ɛyɛ kɔkɔɔ mpofirim. |
| Ɔhome a ɛyɛ den (Wheezing) . | ‘Cheese-cheese’ nnyigyei bere a wɔrehome, a ɛte sɛ ayamtu de. |
| Nnipa a wɔtotɔ piti | Nhumu a ɛyera esiane mogya mmoroso a ɛkɔ fam mpofirim nti. |
| Tipaeɛ | Tipaeɛ. |
Urticaria Pigmentosa ayarefo bɛboro 75% yɛ mmofra a wonnii mfe 10. Wɔ mmofra dodow no ara mu no, saa tebea yi wɔ honam ani nkutoo na sɛ obi nyin a, ɛyɛ yiye.
Ɔkwan bɛn so na oduruyɛfo hu eyi?
Mpɛn pii no, ɛnyɛ den sɛ wo duruyɛfo betumi ahu saa tebea yi denam nsensanee a ɛwɔ wo honam ani a ɔbɛhwɛ na wahwɛ sɛ Darier sɛnkyerɛnne no wɔ hɔ anaa. Sɔhwɛ foforo biara ho nhia.
Nanso, sɛ adwenem naayɛ bi wɔ hɔ sɛ ɛnyɛ honam ani nko na saa tebea yi wɔ na mmom aka nipadua no afã afoforo nso a, oduruyɛfo no betumi akamfo nhwehwɛmu a edidi so yi akyerɛ.
- Mogya mu nhwehwɛmu (`Mogya dodow`): Sua nkwammoaa ahorow ne dodow a ɛwɔ mogya no mu ho ade.
- Serum tryptase nhwehwɛmu: Ɛhwɛ sɛ enzyme bi wɔ mogya no mu a mast cells gyae.
- Bone density scan: Hwɛ sɛnea wo nnompe mu yɛ den.
- Nnompe mu ntini mu nhwehwɛmu: Ɛhwɛ sɛ nnompe mu ntini no reyɛ nkwammoaa a ɛte apɔw anaa.
Akwan a wɔfa so sa yare ne sɛnea wobedi yare no so
Asɛmpa no ne sɛ wɔ mmofra dodow no ara fam no, Urticaria Pigmentosa no ankasa besiesie bere a wɔrenyin no . Ayaresa pɔtee biara nni hɔ a wɔde besiw nsensanee foforo ano. Nsonsonoe a ɛwɔ hɔ dedaw no betumi agye mfe pii ansa na ayera.
Bere tenten a tebea no wɔ honam ani nkutoo no, mpɛn pii no ɛho nhia sɛ wɔde sa yare kɛse biara. Ebia wo duruyɛfo bɛkamfo nea edidi so yi akyerɛ na aboa ma woadi wo yare no ho sɛnkyerɛnne ahorow ho dwuma:
- Nnuru a wɔde kum akisikuru a wɔnom: Siw ɛyaw ne ɔfe so.
- Corticosteroid creams: Fa gu mmeae a ɛyɛ wo yaw.
- Cromolyn sodium: Aduru a wɔde sa yare no ho sɛnkyerɛnne te sɛ ɔfe ne akisikuru.
- EpiPen: Afiri a wɔde ma nnipa a wɔn ho yɛ wɔn hyew kɛse (anaphylactic reaction) sɛ wɔmfa nni dwuma wɔ tebea a egye ntɛmpɛ mu. Ɛnyɛ obiara na ohia eyi.
Nneɛma a ɛsɛ sɛ wɔkwati titiriw
Ade a ɛho hia sen biara wɔ yare yi mu ne sɛ wobɛtwe wo ho afi nneɛma a ɛkanyan yare no ho sɛnkyerɛnne no ho, kyerɛ sɛ, nneɛma a ɛma nsensanee no yɛ mmerɛw na ɛyɛ kɔkɔɔ.
| Nnuru a ɛsɛ sɛ wɔkwati | Nneɛma afoforo a ɛsɛ sɛ yɛkwati |
|---|---|
| Aspirin a wɔde di dwuma | Apɔw-mu-teɛteɛ (titiriw nea ɛyɛ den) . |
| Nsaden | Sɛ wode mpopaho bɛpete honam ani denneennen |
| Nnuru a wɔde kum ɛyaw te sɛ morphine ne codeine (`Opiates`) . | Nsu a ɛyɛ hyew a wɔde guare |
| Thiamine (Vitamin B1) a ɛwɔ nipadua no mu. | Nsã a ɛyɛ hyew |
| Quinine (`Quinine` - aduru a wɔde sa asramma) . | Owia a wɔde di dwuma dodo |
| Dextromethorphan (aduru a wɔde sa ɔfe) . | Awɔw a ano yɛ den a wɔde wɔn ho bɛhyɛ mu |
| Nnuru bi a ɛma obi dwensɔ ne X-ray aduru | Nnuan a ɛyɛ nnuhwam na ɛyɛ hyew |
Nea ɛho hia: Sɛ ɛho hia sɛ wo anaa wo ba nonom nnuru ma tebea foforo a, hwɛ hu sɛ wobɛbɔ wo duruyɛfo amanneɛ wɔ Urticaria Pigmentosa ho.
So nsɛnnennen betumi aba?
Ɛntaa mma koraa sɛ saa tebea yi betumi akɔ so akodu `systemic mastocytosis`. Nnipa a wɔte saa no wɔ asiane kɛse mu sɛ wobenya akisikuru a emu yɛ den a wɔfrɛ no `anaphylactic shock`, a ebetumi de wɔn nkwa ato asiane mu. Sɛ wuhu sɛnkyerɛnne ahorow te sɛ ɛyɛ den sɛ wobɛhome na wo ho atɔ wo , ɛsɛ sɛ wokɔ ayaresabea dwumadibea a wɔhwɛ ntɛmpɛ so (ETU) ntɛm ara .
Nsɛnnennen afoforo a ɛba wɔ nhyehyɛe mu mastocytosis mu ne:
- Nnompe mu yare: Nnompe a ɛyɛ mmerɛw.
- Cytopenia: Mogya mu nkwammoaa a ɛba nipadua no mu no so tew.
- mmerɛbo mu haw ahorow.
- Kokoram (ɛho yɛ na yiye).
Bio nso, eyinom yɛ nsɛnnennen a ɛntaa nsi koraa. Wɔn ho yɛ na koraa wɔ mmofra a wɔwɔ Urticaria Pigmentosa mu.
Nkrasɛm a Wɔde Kɔ Fie
- Urticaria Pigmentosa yɛ honam ani yare a ɛka mmofra titiriw. Ɛnyɛ nea wɔde yare mmoawa ba anaasɛ wonya fi awofo hɔ.
- Nsɛnkyerɛnne titiriw ne sɛ, sɛ wɔde petepete baabi a ɛyɛ bruu a, ɛbɛyɛ kɔkɔɔ, ɛho ahonhon, na ɛyɛ mmerɛw (`Darier sɛnkyerɛnne`).
- Mma nsuro a ɛho nhia, efisɛ tebea yi ankasa bɛyɛ yiye ama mmofra dodow no ara bere a wɔrenyin no.
- Adeyɛ a eye sen biara ne sɛ wobɛtwe wo ho afi nnuan, nnuru, ne dwumadi ahorow a ɛma yare no ho sɛnkyerɛnne no mu yɛ den ho.
- Sɛ wo anaa wo ba no wɔ saa sɛnkyerɛnne yi bi a, hwɛ hu sɛ wobɛkɔ oduruyɛfo nkyɛn akɔhwehwɛ yare no pɛpɛɛpɛ na wama no afotu a ɛho hia.
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