An ka gɛlɛya dɔw dɔn i farikolo ɲɛgɛnɛsira la wa? - Neoplasi endocrine multiple (MEN) .

An farikolo bɛ iko kabako masin, tiɲɛ tɛ? Walasa nin masin in ka baara kɛ ka ɲɛ, a yɔrɔ kelen-kelen bɛɛ ka kan ka baara kɛ ɲɔgɔn fɛ ani ka baara kɛ ɲɔgɔn fɛ ka ɲɛ. Fɛn dɔ bɛ an farikolo la min nafa ka bon kosɛbɛ, o bɛ wele ko endocrine system . Glande minnu bɛ o sigida la, olu bɛ ɔrimɔni (hormones) dilan minnu bɛ an farikolo baara caman ɲɛminɛ. Nka, tuma dɔw la, o cogoya bɛ se ka kɛ cogo jugu la. Bi an bɛna kuma bana dɔ kan min man teli ka sɔrɔ nka a nafa ka bon kosɛbɛ, an ka kan ka min dɔn. O ye Multiple Endocrine Neoplasia ye , a bɛ fɔ fana ko `(MEN)` ni a surunyalen don.

O la sa, nin endocrine system in ye mun ye?

N’an y’a fɔ cogo nɔgɔman na, an ka kɔnɔnatumuw ye glandew ni farikolo yɔrɔw ye minnu bɛ an farikolo kɔnɔ. Olu de bɛ furakisɛw dilan minnu bɛ wele ko ɔrimɔni , ka u bila joli la. Aw k’a miiri ko o ɔrimɔni ninnu ye ciden fitininw ye minnu bɛ cikanw ta an farikolo kɔnɔ. O cikanw b’a fɔ an farikolo yɔrɔw, an fari ani an farikolo yɔrɔw ye an ka kan ka min kɛ ani an ka kan ka o kɛ waati min na.

Glande ni farikolo yɔrɔba damadɔ bɛ yen minnu bɛ an ka endocrine system kɔnɔ:

• Hypothalamus : O bɛ sɔrɔ an kunkolo da la. A bɛ fɛn caman mara endocrine system kɔnɔ.
• Glande pituitaire : Nin gland fitini in min ni hypothalamus cɛsirilen don, o bɛ ɔrimɔni dɔw dilan minnu bɛ glande caman wɛrɛw mara, i n’a fɔ thyroïde glande, surénale glande, ovaire ani cɛya.
• Thyroïde : Nin gland in min bɛ i n’a fɔ wuluwulu min bɛ kɔ ɲɛfɛ, o bɛ an farikolo ka farikoloɲɛnajɛw kɔlɔsi, o de ye an bɛ fanga min sɔrɔ an bɛ dumuni min dun.
• Parathyroïde glandes : Nin gland misɛnnin naani ninnu, minnu ka teli ka sɔrɔ thyroïde gland kɛrɛfɛ, olu bɛ kalisiyɔmu ni fosiporozɛni hakɛ kɔlɔsi an fari la.
• Sugunɛbilenni : Nin gland fila ninnu, minnu bɛ sugunɛ sanfɛ, olu bɛ farikoloɲɛnajɛ, tansiyɔn, cɛnimusoya yiriwali ani degun jaabi kɔlɔsi.
• Pineal gland: O gland bɛ melatonin hormone dilan ani ka an ka sunɔgɔcogo ɲɛnabɔ.
• Pankreyasi : Inisɔn bɛ bɔ yɔrɔ min na. A nafa ka bon kosɛbɛ farikolojɔli ni joli sukaro kunbɛnni na. O fana ye an ka dumunikɛcogo dɔ ye.
• Ovaries : O yɔrɔ de la muso ka cɛnimusoya hormones estrogène, progesterone ani testosterone bɛ bɔ yen.
• Tɔgɔtɔgɔnin : K’a sɔrɔ a bɛ cɛya bɔ cɛw la, ɔrimɔni tetarasikilini fana bɛ bɔ yan.

O la, Neoplasie Endocrine Multiple (MEN) ye mun ye?

Multiple Endocrine Neoplasia (MEN) ye bana ye min man teli ka sɔrɔ jamu fɛ, ni kurukuruw bɛ bɔ endocrine systeme glandes ni farikolo yɔrɔw la minnu ka ca ni kelen ye, an ye baro kɛ o kan ka tɛmɛ. Tuma dɔw la, o kurukuru ninnu bɛ se ka kɛ kansɛri ye.

Nin `(MEN)` cogoya in suguba fila bɛ yen:

1. Endocrine neoplasie multiple type 1 (MEN type 1): Nin ye bana ye min na kuru caman bɛ bɔ endocrine system glandes (glandes) suguya wɛrɛw la. O bɛ wele fana ko MEN-1 ani Wermer ka bana.

2. Endocrine multiple neoplasia type 2 (MEN type 2): Nin ye kansɛri bana ye min bɛ sɔrɔ jamu fɛ, min bɛ gland caman minɛ. MEN2 bɛ mɔgɔ minnu na, olu bɛ kansɛri suguya dɔ sɔrɔ min bɛ wele ko kansɛri min bɛ wele ko medullary thyroïde cancer (MTC) . U fana ka teli ka kurukuruw sɔrɔ farikolojidɛsɛbanakisɛ wɛrɛw la. O bɛ wele fana ko MEN-2 ani Sipple syndrome.

Mun na nin `(MEN)` ko in bɛ kɛ?

Nin `(MEN)` suguya fila bɛɛ bɛ sɔrɔ an ka jamu caman yeli fɛ , o kɔrɔ ye ko fɛn falenw . Miiri k’a filɛ ko fɛn dɔ bɛ an farikolo la i n’a fɔ kalan gafe, o kɔrɔ ye ko jeninida. Ni hali lɛtɛrɛ kelen min bɛ nin kalan gafe in kɔnɔ, o filila, o kɔrɔ ye ko ni fɛn dɔ jiginna jamu dɔ la, farikolo baara dɔw bɛ se ka tiɲɛ.

• (MEN suguya 1) bɛ sɔrɔ fɛn dɔ jiginni fɛ `MEN1` jamu kɔnɔ . Nin `MEN1` jamu in ye tumuw balilan jamu ye . O kɔrɔ ye ko jɛnɛya min bɛ dɛmɛ ka farikolokisɛw tilatilali kunbɛn ani ka tumuw bali ka sɔrɔ. Ni o jɛnɛya ma baara kɛ ka ɲɛ, farikolokisɛ dɔw bɛ se ka bonya ka bɔ u yɛrɛ la, ka kuruw kɛ.
• (MEN suguya 2) bɛ sɔrɔ fɛn dɔ jiginni fɛ `RET` jamu kɔnɔ . Nin `RET` jamu in ye jamu ye min bɛ tali kɛ kansɛri sɔrɔli la. Ni o jɛnɛya in jiginna, farikolo yɔrɔ dɔw ni glandes dɔw kɔnɔ seliluw bɛ bonya cogo la min tɛ se ka kunbɛn, ka kɛ kuruw ye.

Nin jamu caman ɲɔgɔnna caman bɛ se ka sɔrɔ bangebagaw fɛ walima u bɛ se ka kɛ k’a sɔrɔ u ma kɛ cogo si la den falen waati. Ni CƐW bɛ bangebaga kelen na, a bɛ se ka kɛ 50% ɲɔgɔn ye ko den bɛna a sɔrɔ.

An ka dɔ fara an ka dɔnniya kan dɔɔnin `(MEN)` suguya 1 (`MEN suguya 1`) kan

MEN suguya fɔlɔ bɛ mɔgɔ minnu na, olu bɛ kurukuruw sɔrɔ endocrine system glande caman na. Yɔrɔ minnu ka teli ka bana sɔrɔ olu ye:

• Parathyroïde glandes : Nin de ka teli ka kɛ.
• Kɔnɔbara basigilen : O kɔrɔ ye ko kurukuruw bɛ se ka kɛ kɔnɔbara la, kɔnɔbara la, ani dumunikɛminɛnw yɔrɔ wɛrɛw la, i n’a fɔ kɔnɔbara basigilen.
• Glande pituitaire (Glande pituitaire).

A ka ca a la, kuru minnu bɛ bɔ ni MEN suguya fɔlɔ ye, olu tɛ kansɛri ye (banakisɛ) . Nka, kuru dɔw bɛ se ka kɛ kansɛri ye (bana jugu).A bɛ se ka jɛnsɛn (metastasize) fana farikolo yɔrɔ wɛrɛw la. Tumu bɛ gland minnu na, a ka ca a la, olu bɛ ɔrimɔni caman bɔ joli la. O de bɛ kɛ sababu ye ka bana taamasiɲɛ suguya caman ni kɛnɛya gɛlɛyaw lase mɔgɔ ma.

Dɔgɔtɔrɔw ye kuru suguya 20 ni kɔ jira minnu bɛ sɔrɔ kɔnɔbara la ani minnu tɛ kɔnɔbara la, MEN suguya 1 bɛ mɔgɔ minnu na.Kuru suguya wɛrɛw bɛ yen minnu man ca, i n’a fɔ:

• Neuroendocrine tumors minnu bɛ sɔrɔ thymus (disidimi la) ani bronchi (fiɲɛbɔyɔrɔw fogonfogon la).
• Sugunɛbilenni kuruw bɛ sɔrɔ sugunɛbaralabana kɛnɛma yɔrɔ la.
• Kuru tulumaw (Lipomas) minnu bɛ sɔrɔ fari jukɔrɔ.
• Sinna kansɛri.
• Tumuw i n’a fɔ ɲɛgɛnɛsiralabanaw ni kunsɛmɛnasumaya minnu bɛ se ka kɛ kunsɛmɛ na walima kɔkolo la.

`(MEN suguya 1)` taamasiɲɛw ye mun ye?

MEN suguya fɔlɔ taamasiɲɛw bɛ se ka ɲɔgɔn ta kosɛbɛ mɔgɔ ni mɔgɔ cɛ. A bɛ bɔ glande minnu na, ani u bɛ ɔrimɔni hakɛ min bɔ. A bɛ se ka kɛ ko bana taamasiɲɛ tɛ mɔgɔ dɔw la fewu, dɔw bɛ se ka kɛ ni taamasiɲɛ nɔgɔmanw ye, ani dɔw bɛ se ka kɛ taamasiɲɛ jugumanw ye, hali minnu bɛ se ka u ka ɲɛnamaya bila farati la. A taamasiɲɛw bɛ se ka ɲɔgɔn ta mɔgɔ ni ɲɔgɔn cɛ, hali denbaya kelen kɔnɔ, hali filaninw ni ɲɔgɔn cɛ.

An ka kurukuru suguya kunbaba dɔw lajɛ ani u ni ɲɔgɔn cɛ taamasiɲɛw:

• K’a sababu kɛ gɛlɛyaw ye paratayiroyidi glandew la (parathyroïde hyperparathyroïdie):

`(MEN suguya 1)` bɛ mɔgɔ minnu na, olu 90% bɛ nin bana in sɔrɔ u si san 50. O la, paratayiroyidi glandew bɛ kɛ ka tɛmɛ.

• Taamasiɲɛ nɔgɔmanw : kolotugudaw dimi, farikolo fanga dɔgɔyali, sɛgɛn, degun, hakilijagabɔ gɛlɛya, dumuni nege tɛ a la.
• A taamasiɲɛ jugumanw : kɔnɔboli, fɔɔnɔ, hakiliɲagami, ɲinɛni, minnɔgɔ kojugu ani koli ka caya, kɔnɔboli, kolodimi.

• K’a sababu kɛ kurukuruw ye kɔnɔbara la ani banakɔtaa fitini yɔrɔ fɔlɔ (Gastrinomas):

MEN suguya fɔlɔ bɛ mɔgɔkɔrɔba minnu na, olu 40% ɲɔgɔn bɛ kurukuruw sɔrɔ minnu bɛ wele ko gastrinomas. Olu bɛ ɔrimɔni dɔ bɔ min bɛ wele ko gastrin, o bɛ kɛ sababu ye kɔnɔbara ka asidi caman bɔ.

• A taamasiɲɛw : Kɔnɔdimi, kɔnɔboli, dusukundimi (asidi kɔsegin), kɔnɔboli (banakisɛw).
• kuru wɛrɛ min bɛ ye nin kulu in na , o ye insuline ye . O bɛ insuline (insuline) dilan, o bɛ se ka kɛ sababu ye ka sukaro dɔgɔya joli la (hypoglycémie).
• A taamasiɲɛw : hakili ɲagami, yɛrɛyɛrɛ, sumaya, kɔngɔ kojugu, lafiyabaliya, dusukun tantanni teliya, yeli yeli waati dɔɔni.

• K’a sababu kɛ sɔgɔsɔgɔninjɛ ye (prolactinomes):

MEN suguya fɔlɔ bɛ mɔgɔ minnu na, olu 25% ɲɔgɔn bɛ sɔgɔsɔgɔninjɛ sɔrɔ. A ka ca a la, olu ye prolactinomas ye, olu bɛ hormone prolactin dilan .

• Taamasiɲɛ minnu bɛ musow la : kalolabɔbaliya walima kalolabɔ dabila (menorrhea), kɔnɔmaya gɛlɛya, nɔnɔ bɔli sinji la ni u kɔnɔma tɛ walima ni u bɛ sin di den ma (galactorrhea), cɛnimusoya nege bɛ dɔgɔya.
• A taamasiɲɛw cɛw la : Cɛnimusoko nege bɛ dɔgɔya ka a sababu kɛ tetarasikilini hakɛ dɔgɔyali ye, cɛya gɛlɛya (ED), ani kɔnɔmaya gɛlɛya.
• Ni kuru ka bon : kungolodimi, kɔnɔboli/fɔɔnɔ, yeli bɛ yɛlɛma (yeli fila, kɛrɛ yeli dɔgɔyali).

Nafama: Bɛɛ tɛna a taamasiɲɛ kelenw sɔrɔ. Nin lisi in tɛ fɛn bɛɛ lajɛlen ye. Kuru suguya caman wɛrɛw bɛ yen minnu bɛ se ka sɔrɔ MEN suguya 1 na.

An ka `(MEN)` suguya 2 (`MEN suguya 2`) fana dɔn .

MEN suguya 2 bɛ mɔgɔ o mɔgɔ la, o bɛɛ bɛ kansɛri suguya dɔ sɔrɔ min bɛ wele ko kansɛri min bɛ wele ko medullary thyroïde cancer (MTC) . Nin kansɛri suguya in bɛ sɔrɔ farikolokisɛ suguya kɛrɛnkɛrɛnnen dɔ la min bɛ sɔrɔ sɔgɔsɔgɔninjɛ la min bɛ wele ko C cellules. O farikolokisɛw bɛ ɔrimɔni dɔ dilan min bɛ wele ko kalisitɔni. MTC bɛ se ka jɛnsɛn ka taa ɲɛgɛnɛsiraw ni farikolo yɔrɔ wɛrɛw la. Furakɛli kunba ye opereli ye ka ɲɛgɛnɛsira bɔ (thyroïdectomie).

Ani fana, `(MEN type 2)` bɛ mɔgɔ minnu na, olu bɛ se ka nin bana ninnu dɔ walima u fila bɛɛ sɔrɔ:

• Feochromocytoma : Nin ye kuru ye min man teli ka sɔrɔ, a bɛ sɔrɔ sugunɛbaralabana kelen walima a fila bɛɛ cɛmancɛ la (surénaux médulles). A ka ca a la, ninnu tɛ kansɛribana ye. A 10%-15% ɲɔgɔn bɛ se ka kɛ kansɛri ye ka jɛnsɛn.
• Paratayiroyidi (hyperparathyroïdie) : Joli kalisiyɔmu hakɛ bɛ bonya ka a sababu kɛ paratayiroyidi hormone (PTH) bɔli kojugu ye paratayiroyi glandew fɛ.

`(MEN suguya 2)` taamasiɲɛw ye mun ye?

Taamasiɲɛ minnu bɛ yan, olu fana tɛ kelen ye. A ka ca a la, a taamasiɲɛw bɛ sɔrɔ kansɛri (MTC) ni kuru dɔw ka ɔrimɔni caman fɛ.

• Kansɛri min bɛ sɔrɔ ɲɛgɛnɛsira la (MTC) taamasiɲɛw:
• Kuru dɔ bɛ kɛ kɔ ɲɛfɛla la, kɔdimi, kan yɛlɛma (kankari), sɔgɔsɔgɔ, kunumuni gɛlɛya, ninakili gɛlɛya.

• Feochromocytoma taamasiɲɛ minnu bɛ sɔrɔ : (a bɛ sɔrɔ 50% ɲɔgɔn na) .
• A taamasiɲɛw bɛ sɔrɔ dɔrɔn ni o kurukuruw bɛ ɔrimɔni caman bɔ, i n’a fɔ adrénaline. Tumu dɔw tɛ ɔrimɔni bɔ wa a bɛ se ka kɛ u tɛ taamasiɲɛ si jira.
• A taamasiɲɛ minnu ka teli ka ye (a ka ca a la a bɛ na ka taa a fɛ waatiw la): tansiyɔn jiginni (tansiyɔn jiginni), kungolodimi, sumaya kojugu kun tɛ, dusukun tantanni teliya walima a tɛ kɛ cogo la, yɛrɛyɛrɛ.

• Taamasiɲɛ minnu bɛ sɔrɔ paratayiroyidi caya fɛ:
• I n’a fɔ a bɛ kɛ cogo min na `(MEN suguya fɔlɔ)` la, taamasiɲɛw i n’a fɔ kolotugudaw dimi, farikolo fanga dɔgɔyali, sɛgɛn, degun, hakilijagabɔ gɛlɛya, dumunikɛbaliya, kɔnɔboli, fɔɔnɔ, minnɔgɔ kojugu ani koli kɛli tuma caman, kɔnɔboli, ani kolodimi, olu bɛ se ka sɔrɔ.

Jɔn bɛ se ka nin `(MEN)` bana in sɔrɔ? A ka ca cogo di?

Bana `(CƐW)` bɛ se ka cɛw ni musow bɛɛ minɛ cogo kelen na. `(MEN suguya 1)` bana bɛ bɔ san min na, o bɛ danfaraba don. A sɔrɔla denmisɛnniw na minnu si bɛ san 8 la ani balikuw minnu si bɛ san 80 la.

`(CƐW)` ye bana ye min man teli ka sɔrɔ .

• `(CƐW suguya 1)` bɛ mɔgɔ kelen ɲɔgɔn minɛ mɔgɔ 30.000 o 30.000 la.
• `(CƐW suguya 2)` bɛ mɔgɔ kelen ɲɔgɔn minɛ mɔgɔ 35.000 o 35.000 la.

Ɲininikɛla dɔw dalen b’a la ko nin bana ninnu bɛ mɔgɔ minnu na, olu hakɛ yɛrɛ bɛ se ka caya ka a sababu kɛ bana sɛgɛsɛgɛli dɔgɔyali walima a sɛgɛsɛgɛli jugu ye.

Dɔgɔtɔrɔw bɛ bana in `(MEN)` sɛgɛsɛgɛ cogo di? (Sɛgɛsɛgɛli) .

Bana `(MEN)` sɛgɛsɛgɛli bɛ se ka gɛlɛya dɔɔni, barisa a bɛ glande suguya wɛrɛw de minɛ.

• `(MEN suguya 1)` dɔnni:

A ka ca a la, MEN suguya 1 bɛ mɔgɔ sɔrɔ ni a ka dɔgɔn ni a ka dɔgɔn ka kɛ ni kɔnɔnatumu suguya saba ye minnu kofɔlen don sanfɛ (parathyroïde kuru, pituitaire kuru, ani/walima kɔnɔbara basigilen), walima ni o kuru dɔ bɛ a la ani ni MEN suguya fɔlɔ bɛ a ka denbaya kɔnɔmɔgɔ dɔ la.

• Kɔrɔbɔliw:
• Joli sɛgɛsɛgɛli : Aw bɛ a lajɛ ni ɔrimɔni dɔw hakɛ ka ca (misali la paratayiroyidi ɔrimɔni (PTH), kalisiyɔmu).
• Ja sɛgɛsɛgɛliw : Olu bɛ se ka dɛmɛ don ka kurukuru yɔrɔw sɔrɔ, i n’a fɔ CT scan (computer tomography scan) walima MRI (magnetic resonance imaging scan).
• Jɛnkulu sɛgɛsɛgɛli : A bɛ sɛgɛsɛgɛli kɛ ni fɛn dɔ b’a la ka fɛn dɔ sɛgɛsɛgɛ `MEN1` jamu kɔnɔ.

• `(MEN suguya 2)` dɔnni:

MEN suguya 2 bɛ sɔrɔ mɔgɔ la ni kansɛri bɛ a la ni ɲɛgɛnɛsiralabanaw (MTC) bɛ a la ka fara feokɔrɔmositoma ni/walima hyperplasie walima parathyroïde glandes adenoma kan.

• Kɔrɔbɔliw:
• Joli sɛgɛsɛgɛli : Aw bɛ ɔrimɔni hakɛ lajɛ i n’a fɔ kalisitɔni (MTC ta la), paratayiroyidi ɔrimɔni (PTH), ani katekolamini (feochromocytoma ta).
• Jala sɛgɛsɛgɛliw: `CT scan` walima `MRI scan` bɛ kɛ.
• Jɛnkulu sɛgɛsɛgɛli : A bɛ sɛgɛsɛgɛli kɛ ni fɛn dɔ jiginna `RET` jamu la.

`(MEN)` furakɛcogo jumɛnw bɛ yen?

MEN furakɛli bɛɛ bɛ bɔ farikolojidɛsɛbanakisɛw ni farikolo yɔrɔ minnu na. A ka c’a la, a bɛ kɛ ni dɔgɔtɔrɔw ka jɛkulu ye min bɛ baara kɛ ni fɛn caman ye, i n’a fɔ kɔnɔbara basigilenw , operelikɛlaw , ani kansɛri dɔgɔtɔrɔw .

Furakɛli suguya caman bɛ se ka kɛ:

• Fura : Aw bɛ bana taamasiɲɛw kunbɛn ani ka ɔrimɔni tɛmɛnen nɔw dɔgɔya.
• Opereli : Aw bɛ kurukuru walima ɲɛgɛnɛsira bananen bɛɛ bɔ (misali la, sɔgɔsɔgɔninjɛ).
• Ɔrimɔni sinsinni furakɛli : Ni opereli kɛra ka ɲɛgɛnɛsira dɔ bɔ, a bɛ ɔrimɔni minnu bɔ, olu bɛ kɛ kɛnɛma.
• Kansɛri furakɛli : Ni kansɛri jɛnsɛnna yɔrɔ wɛrɛw la (a bɛ taa yɔrɔ wɛrɛw la), furakɛli i n’a fɔ chimiothérapie ani radiation therapy .

Ikomi `(MEN)` banabagatɔ bɛɛ ɲɔgɔn tɛ, furakɛli bolodacogo min bɛ baara kɛ bɛɛ ye, o tɛ kelen ye. Aw kana siran ka kuma aw ka dɔgɔtɔrɔ fɛ furakɛli suguya minnu ka fisa aw ma.

Yala `(MEN)` bɛ se ka kɛnɛya pewu wa? Yala a bɛ se ka bali wa?

A fɔ man di nka sisan, fura tɛ yen `(MEN)` bana in na. Nka, a bɛ se ka ɲɛnabɔ . Dɔgɔtɔrɔw bɛ gland kelen-kelen bɛɛ yeli furakɛ ni opereli walima fura ye i n’a fɔ a bɛnnen don o waati la.

A tɛ se ka kɛ ka `(MEN)` yiriwali bali, bawo a bɛ sɔrɔ jamu jiginni fɛ. O fɛn falenw bɛ se ka sɔrɔ bangebagaw fɛ walima u bɛ se ka kɛ k’a sɔrɔ u ma kɛ cogo si la denso kɔnɔ.

Nka, ni a sɔrɔla ko MEN bɛ denbaya kɔnɔmɔgɔ gɛrɛgɛrɛ dɔ la (bangebaga, balimakɛ), a nafa ka bon ka kuma aw ka dɔgɔtɔrɔ fɛ MEN ka jamu sɛgɛsɛgɛli kan. O kɛli bɛ se ka dɛmɛ ka kuruw dɔn joona ni bana in bɛ aw la.

Mun bɛ kɛ ni i sigilen bɛ ni `(CƐW)` ye? (Pronostic) (Kɔrɔfɔcogo) .

MEN ka ɲɛnamaya ɲɛfɔcogo bɛ bɔ fɛn caman na:

• `(MEN)` dɔnna joona cogo min na.
• Endocrine glandes jumɛnw de bɛ a tɔɔrɔ?
• Kuru in ye kansɛri ye wo, a tɛ kansɛri ye wo.
• Furakɛli suguya min bɛ kɛ.
• Ni kansɛri kuru dɔ jɛnsɛnna farikolo yɔrɔ wɛrɛw la (a bɛ taa yɔrɔ wɛrɛw la) o bɛ wele.

Ni a sɔrɔla ko MEN bɛ aw la, aw ka dɔgɔtɔrɔ bɛ se ka hakilina ɲuman di aw ma aw ka furakɛli ni ɲɛtaa sira kan.

Waati min na aw ka kan ka taa dɔgɔtɔrɔso la ani ɲininkali nafamaw ka kan ka minnu kɛ

Ni a sɔrɔla ko MEN bɛ aw la, aw ka kan ka taa dɔgɔtɔrɔso la tuma bɛɛ walasa ka aw ka bana kɔlɔsi ani ka a lajɛ ni aw ka furakɛli bɛ baara kɛ ka ɲɛ.

Ani fana, ni aw ka denbaya kɔnɔmɔgɔ gɛrɛgɛrɛ dɔ bɛ ni `(MEN)` ye, aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ jamu sɛgɛsɛgɛli ko la, i n’a fɔ a fɔra cogo min ka tɛmɛ.

Ni `(CƐW)` bɛ aw la, a bɛ se ka kɛ ko nafa bɛ aw la ka dɔgɔtɔrɔ ɲininka ɲininkaliw la i n'a fɔ ninnu:

• `(MEN)` sugu jumɛn bɛ ne la?
• (CƐW) bɛ nɔ bila ne farikolo la cogo di?
• Ne ka kan ka n janto bana taamasiɲɛ jumɛnw na?
• Furakɛli suguya jumɛnw bɛ ne bolo?
• Furakɛli fɛɛrɛ suguya wɛrɛw nafa ni u dɛsɛ ye jumɛnw ye?
• A bɛ waati joli ta walasa furakɛli ka ɲɛ?
• Yala ne ka denbaya tɔ ka kan ka sɛgɛsɛgɛli kɛ (CƐW) la wa?

A laban na, fɛn minnu ka kan ka to an hakili la (Take-Home Message) .

Endocrine neoplasie multiple (MEN) ye bana ye min man teli ka sɔrɔ. Ani fana, barisa CƐW bɛ se ka taamasiɲɛ suguya caman lase mɔgɔ ma wa bɛɛ ka bana tɛ kelen ye, a bɛ se ka gɛlɛya tuma dɔw la k’a dɔn ni a bɛ aw la.

Ni taamasiɲɛ kura dɔw bɛ aw la minnu bɛ aw jɔrɔ, walima ni aw ye fɛn dɔw kɔlɔsi aw fari la, a ka fisa ka taa dɔgɔtɔrɔso la.

Hali ni `(MEN)` ko dɔw bɛ kɛ k’a sɔrɔ u ma kɛ cogo si la, a bɛ se ka boli denbayaw kɔnɔ fana. Ni aw somɔgɔw gɛrɛgɛrɛ dɔ bɛ ni `(MEN)` ye, a nafa ka bon kosɛbɛ aw ka jamu sɛgɛsɛgɛli kɛ walasa k’a dɔn ni farati bɛ aw la. Aw bɛ ɲininkali o ɲininkali kɛ aw ka `(CƐW)` bana sɔrɔli la, aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ. U bɛ yen walisa k’i dɛmɛ. Aw kana siran, aw kana siran, ani aw kana siran ka ɲininkaliw kɛ.

` Endocrine neoplasie multiple, MEN, endocrine systeme, hormones, tumors, cancer, MEN type 1, MEN type 2, parathyroïde, pituitaire, pancréas, thyroïde, MTC, pheochromocytome, jamu cogoya, taamasiɲɛw, bana sɛgɛsɛgɛli, furakɛli