Yala aw kolotugudaw tɛ baara kɛ ka ɲɛ wa? An ka kuma myelosuppression kan!

Yala i fana b’a miiri ko i tɛ kɛnɛya dɔrɔn, i bɛ bana tuma bɛɛ, walima i bɛ joli bɔ hali tigɛ fitinin dɔ la, hali ni i bɛ kansɛri furakɛli la walima bana wɛrɛ la wa? O fɛnw kɔfɛ, a bɛ se ka kɛ ko miyɛlosuppression , o ye bana ye min na kolotugudaw tɛ baara kɛ ka ɲɛ . Aw kana aw hakili ɲagami, an ka kuma nin ko in kan cogo nɔgɔman na.

Miyelosuppression ye mun ye? Ni an b’a fɛ ka tiɲɛ fɔ, yala o ye kolotugudaw fanga dɔgɔyali ye wa?

N’an y’a fɔ cogo nɔgɔman na, ɔwɔ! Kolotuguda ye fɛn nɔgɔlen ye min bɛ i ko sɔgɔsɔgɔninjɛ min bɛ i kolow kɔnɔ. Miiri k’a filɛ i n’a fɔ an farikolo joli dilanyɔrɔ . O izini in bɛ joli kuru bilenmanw, joli kuru finmanw ani joli segin furakisɛ miliyari caman dilan, minnu nafa ka bon an ka ɲɛnamaya kama, ka u fara an joli kan. Kɔnɔnatumu suguya kelen-kelen bɛɛ ka baara tɛ kelen ye an farikolo la. Kolotuguda bɛ dɔ fara o bɔli kan walima ka dɔ bɔ a la ka kɛɲɛ ni an farikolo magow ye.

Sisan, bana dɔ la min bɛ wele ko myelosuppression , o kolosinsinnan in ka baara bɛ tiɲɛ kun dɔw la. O kɔ, joli kuruw ni joli segin furakisɛw tɛ se ka bɔ ka ɲɛ. O kunba ye kansɛri furakɛli ye ni chimiothérapie ye. Nka, joli kansɛri suguya dɔw ni banakisɛ dɔw fana bɛ se ka kɛ sababu ye ka kolotugudaw tiɲɛ.

Miyɛlolabana taamasiɲɛ jumɛnw bɛ yen?

A taamasiɲɛw bɛ se ka ɲɔgɔn ta mɔgɔ kelen-kelen bɛɛ la, ka kɛɲɛ ni aw kolotugudaw bɛ joli kuru bilenmanw, joli kuru finmanw walima joli segin furakisɛw bɔ.

Ni joli kuru bilenmanw dɔgɔyara - Jolidɛsɛ

Joli kuru bilenmanw bɛ oksizɛni ta i fari fan bɛɛ la. Ni u man ca , jolidɛsɛ bɛ sɔrɔ. A taamasiɲɛw bɛ se ka kɛ ninnu ye:

• Sɛgɛn
• Ninakilidegun / ninakilidegun
• Dimi bɛ mɔgɔ la
• Dusukun tantanni teliya walima a tɛ kɛ cogo la / dusukun tantannibaliya
• Mankan min bɛ mankan bɔ tulo la, tuma dɔw la, a bɛ fara "thumping" mankan ni dusukun tantanni kan (Pulsatile tinnitus) .
• Kunkolodimi
• Fari kulɛri bɛ kɛ jɛman ye
• Disi dimi

Neutropenie - joli kuru finmanw (kɛrɛnkɛrɛnnenya la neutrophils) dɔgɔyali .

joli kuru finmanw bɛ banakisɛw kɛlɛ minnu bɛ don an farikolo la , ka an tanga banakisɛw ma . joli kuru finman suguya dɔ bɛ wele ko neutrophils . Ni kolotuguda bɛ neutrophils (banakisɛfagalanw) dɔgɔya ka a sababu kɛ mielosuppression (miyɛlosuppression) ye, o bana bɛ wele ko neutropenie . Neutropenie tɛ taamasiɲɛ kɛrɛnkɛrɛnnen si sɔrɔ, nka o de kosɔnBanakisɛw bɛ se ka sɔrɔ tuma caman, o waati de la a taamasiɲɛw bɛ bɔ kɛnɛ kan.

• Sumaya (tuma dɔw la, a bɛ wele ko neutropenie febrile ) .
• Sɛgɛn
• Galaka dimi/banakisɛ (Glodimi/farinji) .
• Nɔgɔmugu funu
• Kurukuruw bɛ da kɔnɔ walima kɔnɔbara lamini na
• Kɔnɔboli
• Jenini ni koli bɛ kɛ, ka a ye ko i ka kan ka koli teliya, ka to ka koli kɛ

Ni joli segin furakisɛw dɔgɔyara - Trombocytopenie

joli segin furakisɛw bɛ joli bɔli kunbɛn . Ni o hakɛw dɔgɔyara, bana dɔ bɛ sɔrɔ min bɛ wele ko trombocytopénie . O bɛ se ka kɛ sababu ye ka:

• Joli min bɛ mɛn sen na, hali ni a bɛ bɔ joginda fitini dɔ la, walima a ka gɛlɛn ka nugu joli dabila.
• Jogindaw bɛ bɔ joona ka tɛmɛ a cogo kɔrɔ kan.
• Nɔgɔ bilenman misɛnniw (i n’a fɔ kurukuru) bɔli senw duguma - o bɛ wele ko petechiae .
• Nɔgɔ bilenman, bulama walima bulama bɛ fari la - o bɛ wele ko purpura .

Ni joli kuru suguya bɛɛ dɔgɔyara - Pancytopenia

Tuma dɔw la, o joli kuru saba bɛɛ — joli kuru bilenmanw, joli kuru finmanw ani joli segin furakisɛw — bɛ se ka dɔgɔya waati kelen na . o bana in bɛ wele ko pansitopeni . I n’a fɔ neutropenie, nin tɛ bana ye a yɛrɛ la, nka a bɛ se ka kɛ furakɛli cogoya dɔ taamasiɲɛ ye min bɛ a kɔnɔ.

Mun na miyelosuppression bɛ kɛ? O sababu ye mun ye?

I n’a fɔ an y’a fɔ cogo min na ka tɛmɛ, chimiothérapie de ye a sababu ye min ka teli ka kɛ . Nka, sababu wɛrɛw fana bɛ yen.

Chimiothérapie, immunothérapie ani myelosuppression

Simifura suguya caman bɛ se ka o sababu kɛ. A ka ca a la dɔw ye:

• Fluorouracil (Fluorouracil) ye
• Oxaliplatini (Oxaliplatini) ye
• Irinotekan (Irinotekan) ye
• Kapesitabini (capecitabine) ye

Ka fara o kan, CAR T-cell furakɛli, farikolo tangalan suguya dɔ , o fana bɛ se ka kolotugudaw baara tiɲɛ ani ka joli kuruw ni joli segin furakisɛw bɔli dɔgɔya.

Joli kansɛriw ni jolilabanaw (myelosuppression).

Joli kansɛri dɔw fana bɛ se ka joli kuruw bɔli bali. Misali la, kansɛriw la i n’a fɔ jolidɛsɛ, sɔgɔsɔgɔninjɛ, ani miyɛloma , kansɛribanakisɛ minnu tɛ cogoya la, olu bɛ bonya kojugu kolotugudaw la, ka joli kuruw ni joli segin furakisɛ kɛnɛmanw bɔli dabila.

Virus ni myelosuppression (banakisɛfagalanw).

Banakisɛ dɔw fana bɛ se ka joli dilancogo tiɲɛ kolotugudaw la. Miiri k’a filɛ, ni banakisɛ dɔ donna farikolo la, an farikolo lafasalifɛnw, n’o ye joli kuru finmanw ye, olu bɛ banakisɛ kɛlɛ. O kɛlɛ in senfɛ, kolotugudaw bɛ se ka joli kuru bilenmanw ni joli segin furakisɛ dɔɔni bɔ. Sɛgɛsɛgɛli dɔw y’a jira ko banakisɛ dɔw bɛ joli dilanyɔrɔw minɛ k’u ɲɛsin kolotugudaw ma, o bɛ dɔ bɔ joli kuruw hakɛ la. Banakisɛ dɔw minnu sɔrɔla ka tali kɛ nin miyɛlosɔrɔbaliya bana in na, olu ye:

• Epstein-Barr banakisɛ (EBV) .
• Sugunɛbilenni C banakisɛ
• Parvovirus B19 (banakisɛfagalan B19).
• Sitomegalovirusi (CMV) .
• Banakisɛ min bɛ kɔnɔboli bila mɔgɔ la (Kɔnɔboli / varicella zoster) .
• Adamadenw ka farikolo tangalanw (VIH) .
• Dengue banakisɛ

Yala miyelosuppression bɛ se ka gɛlɛyabaw lase mɔgɔ ma wa?

Ɔwɔ, tuma dɔw la, o bɛ se ka kɛ sababu ye ka gɛlɛyaw lase mɔgɔ ma minnu bɛ se ka mɔgɔ ka ɲɛnamaya bila farati la . Misali la, joli kuru bilenmanw dɔgɔyali barikama (jolidɛsɛ jugumanba) walima joli segin furakisɛw dɔgɔyali (joli bɔli min tɛ se ka kunbɛn) .

Nafama: Ni aw ye nin taamasiɲɛ ninnu dɔ ye, kɛrɛnkɛrɛnnenya la ni aw bɛ kansɛri furakɛli la, a nafa ka bon kosɛbɛ aw ka dɔgɔtɔrɔ ka ladilikan ɲini joona.

Dɔgɔtɔrɔw bɛ o bana in sɛgɛsɛgɛ ka ɲɛ cogo di?

o bɛ sɔrɔ kosɛbɛ joli sɛgɛsɛgɛli fɛ . Nin joli sɛgɛsɛgɛliw bɛ a lajɛ ni aw kolotugudaw bɛ joli kuruw ni joli segin furakisɛw bɔ ka ɲɛ.

Joli sɛgɛsɛgɛliw i n’a fɔ ninnu bɛ se ka kɛ:

• Joli jate dafalen (CBC) .
• MCV sɛgɛsɛgɛli (Kɔripusi hakɛ dantɛmɛnen / MCV sɛgɛsɛgɛli) .
• RDW sɛgɛsɛgɛli (Selilɛri bilenman tilatilali bonya / RDW sɛgɛsɛgɛli) .
• Retikulositɛri jate
• Joli min bɛ kɛ farikolo lamini na
• MPV sɛgɛsɛgɛli (Plaquettes volume moyen / MPV sɛgɛsɛgɛli) .

Milosuppression furakɛcogo jumɛnw bɛ yen?

Dɔgɔtɔrɔw bɛ o furakɛ ni nin fɛɛrɛ ninnu ye:

• Ni miyɛlolabana sababu ye chimiothérapie ye, chimiothérapie tata hakɛ ka kan ka dɔgɔya walima ka a dabila waati dɔɔni .
• Jolidonni walasa ka dɔ fara joli kuru bilenmanw ni joli segin furakisɛw hakɛ kan.
• Fura minnu bɛ aw kolotugudaw dɛmɛ ka joli kuru ni joli segin furakisɛ caman di aw ma .

Yala o ko bɛ se ka bali ka kɛ wa?

A ka ca a la, miyɛlosɔrɔsi bɛ kɛ kansɛri furakɛli kɔlɔlɔ ye. O la, dɔgɔtɔrɔw bɛ to ka o kɔlɔlɔ ninnu kɔlɔsi kansɛri furakɛli waati. U bɛna aw ka joli sɛgɛsɛgɛliw lajɛ tuma bɛɛ ani ka fɛn dɔw Changer aw ka furakɛli bolodacogo la ni a mago bɛ a la.

Ne bɛ se ka mun makɔnɔ ni ne bɛ ni miyɛlofura ye?

Mɔgɔ caman bɛ nin bana in sɔrɔ barisa u bɛ ka chimiothérapie ta. Ni o don, aw ka dɔgɔtɔrɔ bɛna a kɔlɔsi kosɛbɛ chimiothérapie bɛ ka nɔ bila aw kolotugudaw la cogo min na. A bɛ se ka kɛ aw ka kan ka lafiɲɛ dɔɔnin kansɛri furakɛli la walasa ka a to aw kolotugudaw ka se ka a joli kuruw hakɛ caya kokura.

Ne bɛ se ka ne yɛrɛ ladon cogo di?

miyɛlosupɛrizini bɛ se ka dɔ fara aw ka banakisɛw ni joli bɔli farati kan . Aw bɛ se ka nin fɛn ninnu kɛ walasa ka dɔ bɔ o farati la:

• Aw bɛ bolociw kɛ walasa ka aw tanga banakisɛw ma minnu ka ca.
• Saniyacogo ɲumanw dege , i n’a fɔ ka to ka aw tɛgɛ ko ani ka aw yɔrɔ janya banabagatɔw la.
• aw bɛ aw yɛrɛ tanga ko minnu ma , aw bɛ se ka jogin walima ka tigɛ . Misali la, i k’i janto ni i bɛ baara kɛ ni marifa nɔgɔlenw ye.

Ne ka kan ka ɲininkali jumɛnw kɛ n ka dɔgɔtɔrɔ la?

Aw bɛ se ka dɔgɔtɔrɔ ɲininka ɲininkaliw la i n’a fɔ:

• Mun na nin miyelosuppression bana in bɛ ne la?
• O bana bɛ nɔ bila ne farikolo la cogo di?
• Furakɛli suguya jumɛnw bɛ ne bolo?
• Yala furakɛli bɛna ne ka myelosuppression furakɛ pewu wa?

Kuma surun: Fɛn minnu ka kan ka to an hakili la (Take-Home Message) .

Aw kolotugudaw ye aw farikolo yɔrɔ nafamaba ye. Joli kuru bilenman minnu bɛ oksizɛni ta, joli kuru finman minnu bɛ banakisɛ kɛlɛ, joli segin furakisɛ minnu bɛ i joli dɛmɛ ka a kuru – u bɛɛ dilannen don yen. Miyelosuppression ye ni aw kolotugudaw ye baara dabila kun dɔw la. A sababu ka teli ka kɛ chimiothérapie ye kansɛri la, nka a bɛ se ka sɔrɔ joli kansɛri ni banakisɛ dɔw fana fɛ. Kana jɔrɛ. Dɔgɔtɔrɔw bɛna a sababu sɔrɔ k’a furakɛ ka kɛɲɛ ni o ye. Min nafa ka bon kosɛbɛ, o ye ka taa dɔgɔtɔrɔso la ni taamasiɲɛ dɔw bɛ aw la minnu tɛ deli ka kɛ ani ka u ka laadilikanw labato ka ɲɛ. Aw kelen tɛ, dɔgɔtɔrɔ dɔw bɛ yen minnu bɛ se k’aw dɛmɛ nin taama in na.

` Miyelosuppression, Kolotugudaw damatɛmɛni, Kolotugudaw, Joli kuru bilenmanw, Joli kuru finmanw, joli segin furakisɛw, Chimiothérapie, Kansɛri, Jolidɛsɛ, Neutropenie, Thrombocytopenie, Banakisɛw