Míaƒe Ŋutilã Dzɔla: Kpekpeɖeŋunaɖoɖoa Gɔmesese - Nirogi Lanka

Èbu asrafo nusuekpɔmɔ̃ siwo le dɔ wɔm ɖeɖimateameŋutɔe le mewò be woakpɔ tawò tso dɔléle me ŋu kpɔa? Ametakpɔnu wɔnuku aɖe le wò ŋutilã me, eye eƒe akpa vevi aɖee nye nane si míeyɔna be ‘Kpekpeɖeŋunaɖoɖo.’ Togbɔ be ŋkɔa aɖi le ɖoɖo nu vie hã la, ewɔa dɔ gã aɖe si xɔa ame ɖe agbe na wò!

Eyata nuka tututue Kpekpeɖeŋunaɖoɖoa wɔna?

Kpuie ko la, kpeɖeŋutɔ ƒe dɔwɔwɔ le abe ametakpɔnu gbãtɔ si le wò dɔlélenutsiŋutete me ene. Bu wò ŋutilã abe dukɔ si aʋakɔ aɖe kpɔ ta na ene; kpeɖeŋutɔ ƒe ɖoɖoae nye asrafoha tɔxɛ veviwo ƒe hatsotso si ƒua du yia ŋgɔgbe fliwo dzi ne wokpɔ ŋɔdzinu aɖe.

Dɔ vevi siwo wòwɔna dometɔ aɖewoe nye:

• De dzesi ŋɔdzinu siwo ate ŋu agblẽ nu le ame ŋu, abe dɔlékui siwo gblẽa nu le ame ŋu (le kpɔɖeŋu me, dɔlékuiwo) ene, kple woƒe taɖodzinu. Ewɔa nu abe ŋkutsala bibi aɖe si fiaa afisi tututu futɔ aɖe le ene.
• Kpekpeɖeŋu nana le dɔyɔyɔ me ɣesiaɣi si abi alo dɔlékui aɖe le ŋuwò. Ènya alesi teƒe aɖe biãna eye wòvuvuna le abixɔxɔ vɔ megbea? Nuɖoanyi siae kpɔa ɖoɖo ma si woyɔna be ‘ dɔdzẽ ’ ( dɔdzẽ ) dzi. Enye nuwɔna si hiã eye wòle lãmesẽ me ne wokpɔ edzi nyuie.
• Lãmenugbagbevi siwo gblẽ la ɖeɖeɖa be woaʋu mɔ na lãmenugbagbevi yeye siwo le lãmesẽ me ƒe tsitsi. Ewɔa dɔ abe dzadzɛnyenyedɔwɔlawo ene, eɖea gbeɖuɖɔwo ɖa ale be ame kukua nate ŋu adzra eɖokui ɖo.
• Duta dɔlékui siwo menye wò ŋutilã tɔ o ɖeɖeɖa.

Nya ‘kpeɖeŋutɔ’ fia be woawu enu alo ado alɔe. Wotsɔ ŋkɔ na nuɖoanyi sia nenema elabena ewɔa dɔ abe ŋusẽ sesẽ aɖe si kpena ɖe ame ŋu ene, si kpena ɖe dɔlélenutsiŋutete ƒe lãmenugbagbevi bubuwo ƒe dɔwɔwɔ ŋu be wòakpɔ egbɔ be wò ŋutilã ƒe ametakpɔnuwo wɔa dɔ nyuie ŋutɔ.

Amekawoe nye Kpekpeɖeŋunaɖoɖoa me tɔwo?

Mina míalé ŋku ɖe amesiwo wɔ ŋusẽ gã sia ŋu. Protein tɔxɛ siwo woyɔna be plasma proteins , siwo ƒoa xlã wò ʋu lae le kpeɖeŋutɔ ƒe ɖoɖoa me. Àhiã nusuekpɔmɔ̃ hafi akpɔ wo, eye protein siawo ƒomevi vovovo siwo ade 50 ye li, eye dɔdasi vevi aɖe koŋ le wo dometɔ ɖesiaɖe si.

Aleke protein siawo wɔa dɔe?

Esia nye nuwɔna dodzidzɔname aɖe. Zi geɖe la, protein siawo nɔa alɔ̃ dɔm alo ‘tsi’ nɔnɔme me , eye le nyateƒe me la, wonɔa lalam. Gake ne xaxa aɖe do mo ɖa—abe abi alo dɔlékui aɖe ƒe amedzidzedze ene—la, ‘wonyɔna’ enumake eye ‘woʋuna’.

Mɔ̃a nya kpɔ ŋutɔ, abe domino fefe ene. Ne protein ɖeka wɔ dɔ la, eʋãa esi kplɔe ɖo, si ʋãa esi kplɔe ɖo, si wɔnɛ be ‘kɔsɔkɔsɔ ƒe dɔwɔwɔ’ dona. Le atikewɔwɔ me la, míeyɔa esia be ‘tsidzadza.’ Protein ɖesiaɖe wu eƒe ametakpɔdɔ tɔxɛa nu eye emegbe wònaa dzesi esi kplɔe ɖo be wòanyɔ. Enye dɔwɔwɔ si ŋu ɖoɖo le ŋutɔ eye wòwɔa dɔ nyuie!

Afikae Complement System la le?

Wò aklãe wɔa protein vevi siawo . Ne wonya wɔ wo ko la, woɖea asi le wo ŋu yia wò ʋukawo me, wozɔa mɔ toa wò ŋutilã bliboa me heɖoa wò lãkusiwo gbɔ. Esia fia be dzɔla siawo le tsa ɖim le wò ɖoɖoa ƒe dzogoe ɖesiaɖe dzi ɣesiaɣi, hele kuxi ƒe dzesiwo dim.

Nukae dzɔna ne Complement System la mewɔ dɔ nyuie o?

Abe alesi nènyae fifia ene la, ɖoɖo sia le vevie ŋutɔ na wò lãmesẽ. Ne nane gblẽ alo dɔmawɔmawɔ nyuie la, ele abe asrafoha si me asrafo alo aʋawɔnu nyui aɖeke mele o ene—wò dukɔa va zua afisi wòate ŋu adze afɔku le.

Zi geɖe la, kuxiwo doa mo ɖa le mɔ eve nu:

1. Ne kpeɖeŋutɔ proteinwo mesɔ gbɔ o alo womele dɔ wɔm nyuie o (Complement Deficiency):

Ne protein siawo mesɔ gbɔ o alo womewɔa dɔ o la, wò dɔlélenutsiŋutete gbɔdzɔna.Esia ate ŋu ana ‘dɔlélenutsiŋutete nagbɔdzɔ.’ Ame ɖekaɖeka siwo le nɔnɔme sia me ate ŋu axɔ dɔlékuiwo enuenu, eye wo dometɔ aɖewo ate ŋu asẽ ŋutɔ, abe dɔlékuiwutikewo ene .

2. Ne protein siwo kpe ɖe eŋu le dɔ wɔm akpa (Overactivity):

Ɣeaɖewoɣi la, protein siawo wɔa dɔ akpa alo dzona madzemadzee. Esia ate ŋu ana ɖoɖoa nagblẽ nu le wò ŋutɔ wò lãmenugbagbevi siwo le lãmesẽ me ŋu. Dɔwɔwɔ fũ akpa sia ate ŋu ahe dɔlélenutsiŋutete ƒe dɔléle vovovowo vɛ (afisi dɔlélenutsiŋutete dzea ŋutilã dzi le) kple dɔdzẽ ƒe nɔnɔme siwo nɔa anyi didi .

Kpekpeɖeŋunaɖoɖoa ate ŋu akpɔ gome le lãmesẽkuxi vovovowo me, siwo dometɔ aɖewoe nye:

• Asrã si ŋu nulɔdɔ le
• Ʋusɔgbɔdɔ
• Kansa aɖewo , abe Ʋumenugbagbeviɣidɔ kple Lãmetsiŋusẽ ene
• Ayikudɔléle
• Macular degeneration ( ŋku ƒe lãmesẽkuxi aɖe) .
• Rheumatoid arthritis (nɔnɔme si nana ƒunukpeƒewo vuvu eye wòsea veve) .

Nukawoe nye nuxlɔ̃amedzesi siwo fia be nya aɖe ate ŋu ado mo ɖa le Complement System la ŋu?

Ne kpeɖeŋutɔ ƒe ɖoɖoa mewɔa dɔ nyuie o la, wò dɔlélenutsiŋutete ate ŋu agblẽ. Ne ède dzesi dzesi siawo enuenu la, ele vevie be nàbia wò ɖɔkta be wòada wò kpɔ.

Nuxlɔ̃amedzesi siwo bɔ dometɔ aɖewoe nye:

• Dɔlékuiwo xɔxɔ enuenu: Aɖuɖɔtoe alo asrã xɔxɔ enuenu, alo ɣeyiɣi didi si mebɔ o si wòxɔna hafi wòhayana tso dɔléle suesuesuewo me.
• Ðeɖiteameŋu atraɖii: Sese le eɖokui me be tsi le ye ŋu alo ɖeɖi te ye ŋu ne yegbɔ ɖe eme nyuie gɔ̃ hã.
• Ƒunukpeƒewo ƒe vevesese.
• Ametia ƒe akpa vovovowo vuvu alo abi.

Aleke wodoa nye Complement System ƒe lãmesẽ kpɔnae?

Ne èle dɔlélewo lém enuenu alo dzesi siwo míeyɔ ɖe etame la, wò ɖɔkta ate ŋu atso nya me be yeada wò kpeɖeŋutɔ ƒe ɖoɖoa kpɔ. Ʋudodokpɔ koŋue wɔa esia .

• Complement test: Ʋudodokpɔ sia dzidzea complement protein ƒe agbɔsɔsɔ eye wòdaa alesi wole dɔ wɔm nyuie la kpɔ. Wò ɖɔkta ate ŋu alé ŋku ɖe protein aɖewo koŋ alo nuɖoanyi bliboa ŋu akpɔe ɖa be dɔléle aɖe ƒe gbɔdzɔgbɔdzɔ alo nuwɔna si gbɔ eme ƒe nya aɖe li hã.

Dodokpɔ siawo ate ŋu akpe ɖe ame ŋu wòanya:

• Nusi gbɔ dɔlékuiwo xɔxɔ enuenu tsona.
• Ne dɔlélenutsiŋutete ƒe dɔléle aɖe le ŋuwò kple alesi wò atikewɔwɔa le dɔ wɔm nyuie.
• Wò dɔlélenutsiŋutete ƒe lãmesẽ ƒe nɔnɔme bliboa.

De dzesii: Ne èkpɔ dzesiwo abe dzoxɔxɔ sesẽ, gbɔgbɔ sesẽ, alo vuvu sesẽ ene la, taflatse yi atikewɔƒe le kɔdzi ƒe dɔwɔƒe si te ɖe ŋuwò kpata alo nàƒo ka na dɔwɔƒe si kpɔa nudzɔdzɔ kpatawo gbɔ enumake.

Tsɔ kpe ɖe esia ŋu la, ne wò ɖɔkta susu be nya aɖe le wò dɔlélenutsiŋutete ŋu la, ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo, abe:

• Ʋu Xexlẽme Blibo (CBC): Esia naa wò ʋumenugbagbeviɣiwo, siwo dometɔ aɖewoe nye ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo, ŋuti nyatakaka tsitotsito.
• Immunoglobulin (antibody) ƒe agbɔsɔsɔ: Esiawo nye protein vevi siwo wɔa akpa vevi aɖe le alesi wò dɔlélenutsiŋutete wɔa dɔe me.

Atike kawoe li na complement system disorders?

Ne dɔléle aɖe si do ƒome kple kpeɖeŋutɔ ƒe ɖoɖoa le ŋuwò la, atikewɔwɔmɔnua aku ɖe wò dzesiwo dzi kpɔkpɔ kple nusi gbɔ wòtso gbɔ kpɔkpɔ ŋu —eɖanye dɔlélea ƒe gbɔdzɔgbɔdzɔ alo dɔlélenutsiŋutete ƒe dɔwɔwɔ fũ akpa o.

Dɔdamɔnu siwo wozãna zi geɖe dometɔ aɖewoe nye:

• Dɔlékuiwutikewo:Be woada dɔlékuiwo ƒe dɔlékuiwo ahakpɔ wo gbɔ.
• Atikewɔwɔ: Wozãnɛ le kansadɔ aɖewo koŋ alo dɔlélenutsiŋutete ƒe nɔnɔmewo me tsɔ trɔa asi le dɔlélenutsiŋutete ƒe dɔwɔwɔ ŋu.
• Dɔlélenutsiŋutete ƒe atikewɔwɔ: Wotrɔ asi le eŋu be wòana dɔlékuiawo nafa ne wò kpeɖeŋutɔ ƒe dɔwɔɖoɖoa le dɔ wɔm akpa.
• Ʋu alo ʋumenugbagbeviɣi dodo: Wozãnɛ tsɔ naa protein siwo hiã siwo kpena ɖe ame ŋu nenye be dɔléle aɖe si ŋu woŋlɔ nu tsoe le ŋuwò.
• Atikewɔmɔnu: Be woanya atikewɔmɔnu yeyewo—vevietɔ ɖe aklãdɔléle ŋu —le vevie ŋutɔ, elabena amesiwo ƒe kpeɖeŋutɔ ƒe ɖoɖo si gblẽ la le afɔku gã aɖe me be woaxɔ kuxi sesẽ siwo tso dɔlékui mawo gbɔ.

Aleke mawɔ ana nye kpeɖeŋutɔ ƒe ɖoɖoa nanɔ lãmesẽ me?

Togbɔ be màte ŋu atrɔ alesi kpeɖeŋutɔ ƒe dɔwɔwɔ wɔa dɔe tẽ o, elabena enye wò nugbagbeŋutinunya ƒe akpa aɖe le dzɔdzɔme nu hã la, àte ŋu ado alɔ wò dɔlélenutsiŋutete bliboa ƒe lãmesẽ. Dɔlélenutsiŋutete si le lãmesẽ me kpena ɖe kpeɖeŋutɔ ƒe dɔwɔwɔ ŋu wòwɔa eƒe dɔwo nyuie.

Nusi nàte ŋu awɔ atsɔ ado alɔ wò nyonyoe nye esi:

• Wɔ mɔxexe ɖe abixɔxɔ nu: Lé ŋku ɖe nusiwo ƒo xlã wò ŋu be nàƒo asa na afɔku siwo mehiã o.
• Lé nuɖuɖu si da sɔ me ɖe asi: De atikutsetse, amagbe geɖe eme, eye nànɔ tsi dzadzɛ me.
• Kamedede edziedzi: Aɖabaƒoƒo 30 ƒe azɔlizɔzɔ bɔbɔe gbesiagbe gɔ̃ hã ate ŋu ana wò lãmesẽ nanyo ɖe edzi ŋutɔ.
• Wɔ dzadzɛnyenye ƒe nɔnɔme nyuiwo: Asikɔklɔ enuenu kple dzadzɛnyenye me léle ɖe asi nye wò ametakpɔnu gbãtɔ.
• Tsɔ alɔ̃dɔdɔ nyuie ɖo nɔƒe gbãtɔ: Ðoe kplikpaa be yeadɔ alɔ̃ nyuie gaƒoƒo 7–8 zã sia zã.

Bu wò kpeɖeŋutɔ ƒe ɖoɖoa be enye wò ŋutilã ƒe kpekpeɖeŋunaha si tsɔ eɖokui na, si le dɔ wɔm ɖeɖimateameŋutɔe be yeakpɔ yeƒe lãmenugbagbeviwo ta tso gotagome ŋɔdzidonamewo kple ememe nugbegblẽwo me. To agbenɔnɔ si me lãmesẽ le me léle ɖe asi, ɖiɖiɖeme si sɔ, kple nuɖuɖu nyuie me la, ke èle nɔnɔme nyuitɔ nam wò kpeɖeŋutɔ ƒe ɖoɖoa be wòakpɔ tawò nyuie.

Nu Vevi Siwo Wotsɔna Yia Nu

Mele mɔ kpɔm be numedzodzro sia na nèse alesi ‘Kpekpeɖeŋunaɖoɖo’ wɔa dɔ le wò me gɔme nyuie wu.

Kpuie ko la:

• Kpekpeɖeŋunamɔ̃a nye wò dɔlélenutsiŋutete ƒe akpa vevi aɖe —bu eŋu abe dzɔla suesuesuewo ƒe ha aɖe si le tsatsam le wò ŋutilã ŋu ene.
• Protein tɔxɛ siwo le ʋumenugbagbevi dzĩ me siwo kplɔ wo nɔewo ɖoe le eme .
• Eƒe dɔ vevitɔe nye be wòaʋli wò ta tso dɔlékuiwo si me, akpɔ abi ƒe hayahaya gbɔ, eye wòaɖe lãmenugbagbevi siwo gblẽ la ɖa.
• Nusiwo gbɔdzɔ alo nuwɔwɔ fũu akpa le ɖoɖo sia me ate ŋu ahe lãmesẽkuxi vovovowo vɛ.
• Ne èkpɔa dɔlékuiwo enuenu, ɖeɖi tea ŋuwò atraɖii, alo ƒunukpeƒeveame si womate ŋu aɖe o la, taflatse yi lãmesẽdɔwɔla aɖe gbɔ.
• Dodo ɖe wò dɔlélenutsiŋutete ƒe lãmesẽ bliboa dzi ɖea vi na wò kpeɖeŋutɔ ƒe dɔwɔwɔ tẽ.

Mègatsi dzi o, elabena dɔdzikpɔkpɔmɔnu nyuiwo li na nɔnɔme siawo. Afɔɖeɖe vevitɔe nye be nàbia wò ɖɔkta ne èsusu be nya aɖewo le ye ŋu. Le Nirogi Lanka , míetea gbe ɖe edzi be wò ɖɔktae nye wò zɔhɛ nyuitɔ kekeake le lãmesẽnya siawo me toto kple mɔ nyuitɔ didi me. Ne èdze ŋgɔ atikewɔwɔ ƒe nɔnɔme kpata aɖe la, taflatse ƒo ka na 911 alo yi dɔwɔƒe si te ɖe ŋuwò si kpɔa nudzɔdzɔ kpatawo gbɔ enumake.