Ðe lã dzĩ ƒe nulɔdɔ wɔnuku aɖe le fu ɖem na wòa? Na míasrɔ̃ nu tso Alpha-gal Syndrome ŋu!

Èbu nusitae nulɔdɔ ƒe dzesiwo ate ŋu adze ye dzi le lã dzĩ abe nyilã, haƒoƒo, alo gbɔ̃ ene ɖuɖu vɔ megbe ŋu kpɔa? Ðewohĩ aɖuɖɔ ado wò, alo ƒodo ado dziku na wò, alo gbɔgbɔ anɔ sesẽm na wò. Ðewohĩ aɖi nusi wɔ nuku, gake le nyateƒe me la, anya wɔ. Egbea míele nu ƒom tso nulɔdɔ wɔnuku aɖe, gake wòle vevie ŋutɔ, ŋu. Woyɔa esia be Alpha-gal Dɔléle.

Nukae nye Alpha-gal Dɔléle? Mina míase egɔme bɔbɔe!

Kpuie ko la, Alpha-gal Syndrome (AGS) nye nuɖuɖu ƒe nulɔdɔ sesẽ aɖe si mebɔ kura o si dzɔna ne èɖu lã dzĩ siwo tso lã siwo naa no wo viwo gbɔ (le kpɔɖeŋu me, nyilã, haƒoƒo, gbɔ̃, gbɔ̃lã). Zi geɖe la, edzɔna ne ʋetsuvi ƒomevi aɖewo ɖu wò vɔ, vevietɔ ne woɖu wò zi geɖe. Abe alesi nènyae ene la, ʋetsuviwo nye dɔlékui suesuesue siwo léna ɖe lãwo ŋu eye wonoa woƒe ʋu.

Azɔ kpɔ ɖa, carbohydrate molecule aɖe si woyɔna be alpha-gal le ʋetsuvi aɖewo ƒe aɖuɖɔ me. Ne alpha-gal molecule sia ge ɖe míaƒe ʋukawo me le ʋetsuvi ƒe ɖuɖu vɔ megbe la, ate ŋu ana míaƒe ŋutilã nase veve ɖe lã dzĩ nu. Nusi dzɔnae nye be míaƒe dɔlélenutsiŋutete dea dzesi lã dzĩ be enye nusi gblẽa nu le ŋutilã ŋu eye wòdzea nuwɔwɔ ɖe eŋu gɔme. Abe futɔ ene. Emae hea nulɔdɔ ƒe dzesi mawo vɛ. Menye lã dzĩ koe amesiwo ŋu AGS le ate ŋu anye nulɔdɔ o, ke boŋ atike bubu siwo me alpha-gal le hã, le kpɔɖeŋu me, atike aɖewo kple adzalẽwo.

Nublanuitɔe la, atike aɖeke meli na AGS fifia o. Gake mègatsi dzi o. Àte ŋu awɔ dɔ kple wò ɖɔkta be nàdi mɔ siwo dzi nàto aƒo asa na nusiwo aʋã wò eye nànɔ lãmesẽ me.

Nukae woyɔna be molecule sia be Alpha-gal?

Alpha-gal nye carbohydrate, alo ne míagblɔe tututu la, sukli molecule, si le lã siwo naa no wo viwo dometɔ geɖe ƒe lãmenugbagbeviwo me. Gake womewɔnɛ le dzɔdzɔme nu le amegbetɔ ƒe ŋutilã me o. Esia tae míaƒe ŋutilã doa dziku ne ʋetsuvi ɖui.

Nuɖuɖu kple nusiwo wowɔ kawoe me Alpha-gal le?

Nusiwo ate ŋu anye esiwo me alpha-gal anɔ dometɔ aɖewoe nye:

• Lã dzĩ: Nuwo abe haƒoƒo, nyilã, avugbɔ̃e, alẽvi, gbɔ̃, nyitsu, kple lãlã ene.
• Atikewɔnuwo kple atikewo: Le kpɔɖeŋu me, atike si nye Cetuximab, si wozãna na kansa.
• Nusiwo wotsɔ lã siwo naa no wo viwo wɔe: gelatin, nyi ƒe notsi, kpakple adzalẽ, kreme, kple aƒemenuzazã aɖewo ate ŋu anye nusiawo.

Bu eŋu kpɔ ko, alfa-gal sia ƒe agbɔsɔsɔ sue aɖe ate ŋu anɔ ice cream alo cheese si nèɖuna gɔ̃ hã me. Eyata ele be nàɖɔ ŋu ɖo ŋutɔ.

Azɔ hã, ame aɖewo siwo ŋu AGS le ate ŋu awɔ nu ɖe ​​atike siwo me nusi woyɔna be carrageenan le ŋu. Carrageenan nye nusi wozãna zi geɖe tsɔ naa nuɖuɖuwo ƒoa ƒu hedzraa wo ɖo. Woate ŋu akpɔe le nusiwo le abe nuku ƒe notsi, lãgbalẽ, kple yogurt ene me.

Amekae ate ŋu axɔ Alpha-gal Syndrome?

Esia ate ŋu adzɔ ɖe ame sia ame dzi, ne ame aɖe si lã dzĩ ƒe nulɔdɔ medzɔ kpɔ o gɔ̃ hã. Ke hã, ame tsitsiwo ŋue wokpɔnɛ le wu.

Ame siwo zãa ɣeyiɣi geɖe le gota siwo me ʋetsuviwo bɔ ɖo, abe agbledeƒewo kple avewo ene, la le afɔku gã aɖe me be woaxɔ AGS. Le Sri Lanka hã la, enyo be amesiwo wɔa dɔ le teƒewo abe avewo alo agble siwo me lãwo le ene hã nanya nu tso esia ŋu.

Akpɔkplɔ ka ƒomevie hea AGS vɛ?

Le United States la, ɣletivimefakaka si nye lone star tick ye nye ʋetsuvi si bɔ wu si do ƒome kple AGS. Gake ʋetsuvi ƒomevi bubuwo li siwo ate ŋu ahee vɛ le xexeame ƒe akpa vovovowo. Le kpɔɖeŋu me:

• Blacklegged tick le Amerika
• "Cayenne tick" le Titina Amerika
• Asiatɔwo ƒe ʋetsuvi si ƒe dzo didi le Asia

Nu vevitɔe nye be nàɖɔ ŋu ɖo ne ʋetsuvi aɖe ɖu wò eye nàdi atikewɔlawo ƒe aɖaŋuɖoɖo ne ehiã.

Ðe ŋkɔ bubuwo li na Alpha-gal Dɔléle sia?

Ẽ, ŋkɔ bubu geɖewo hã le esia ŋu:

• Alpha-gal ƒe nulɔdɔ
• No lãwo ƒe lã ƒe nulɔdɔ
• Lã dzĩ ƒe nulɔdɔ
• Tick ​​bite lã ƒe nulɔdɔ

Nukae hea Alpha-gal Dɔlélea vɛ? Nukatae esia dzɔna ɖo?

Woƒo nu tso nɔnɔme sia ŋu zi gbãtɔ le ƒe 2009. Akpɔkplɔ siwo tsɔa molecule si woyɔna be alpha-gal le woƒe aɖuɖɔ me ƒe ɖuɖu gbɔe wòtsona. Togbɔ be protein gbɔe nuɖuɖu ƒe nulɔdɔ bubu akpa gãtɔ tsona hã la, carbohydrate (sukli) ƒe molecule aɖe gbɔe esia tsona, eyata exɔa ɣeyiɣi aɖe hafi nusi wòwɔna la dzena. Ema fia be zi geɖe la , dzesiawo dzena le gaƒoƒo eve va ɖo ade le lã dzĩ ɖuɖu vɔ megbe . Wosusu be esia tso esime míaƒe ŋutilã xɔa ɣeyiɣi didi hafi ɖua carbohydrates wu protein.

Ðɔktawo menya nusita tututu alpha-gal sia nana lã dzĩ alo kansatike si míeyɔ va yi si nye Cetuximab ƒe seselelãme nɔa ame ŋu haɖe o. Nenema ke wogale numekuku wɔm le nusita ame aɖewo xɔa AGS evɔ ame bubuwo ya mexɔe o.

Nukae nye Alpha-gal Dɔléle ƒe dzesiwo?

Esia ƒe dzesiwo ate ŋu ato vovo ŋutɔ. Ame aɖewo ate ŋu akpɔ dzesi siwo nu mesẽ kura o, evɔ ame bubuwo ya ate ŋu akpɔ dzesi sesẽ siwo ate ŋu ade woƒe agbe afɔku me.

Nusiwo ŋu ŋutigbalẽ gblẽna le wue nye:

• Ŋutilã ƒe ʋuʋu vevie (ɖɔktawo yɔnɛ be ʋuʋudedi) .
• Ŋutilã ƒe biã kple abi (si woyɔna hã be ŋutigbalẽ ƒe ʋuʋu) .
• Ŋutilã me ʋuʋudedi, ʋuʋudedi siwo le abe koklozi ene (woyɔa esia be urticaria alo hives) .
• Nuyi, ŋkume, ŋɔti, aɖe, alo mo ƒe vuvu (woyɔa esia be angioedema) .

Nuɖuɖumeŋusẽ ƒe kuxiwo hã ate ŋu ado mo ɖa, ɣeaɖewoɣi la, esiawo koe:

• Dɔgbo ƒe vevesese, ƒodo ƒe vevesese
• Dɔmetɔtrɔ
• Dzimeve, nuɖuɖumadzroame
• Nuɖuɖumadzroame, nuɖuɖumaɖumaɖu (nuɖuɖumeŋusẽ ƒe dɔmawɔmawɔ nyuie) .
• Lãmetsiwo ƒe ʋuʋu
• Aɖuɖɔtoe alo ʋuʋudedi

Alpha-gal ƒe dɔlélea ate ŋu ahe dzesi siwo do ƒome kple lãkusiwo hã vɛ. Afɔku le esiawo me ŋutɔ:

• Anaphylaxis: Esiae nye esi me afɔku le wu. Nulɔdɔ sesẽ si ate ŋu axe mɔ ɖe gbɔgbɔ nu eye wòade ame ƒe agbe afɔku me. Ne gbɔgbɔ sesẽ na wò la, yi kɔdzi si te ɖe ŋuwò enumake alo nàƒo ka na 911.
• Kpe
• Yagbɔgbɔ sesẽ, gbɔgbɔtsixetsixe (gbɔgbɔtsixetsixe) .
• Ʋuʋudedi

Dzesi bubuwo hã ate ŋu anɔ eŋu:

• Ƒunukpeƒetetedɔ (esia mebɔ vie o) .
• Dzi ƒe tsotso, sese le ɖokuiwò me abe ɖe wò akɔta le ƒoƒom ene
• Ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) .
• Mast cell activation syndrome, si nye dɔlélenutsiŋutete ƒe dɔléle si mebɔ o (si hã mebɔ o) .

Ðe nu bubu aɖewo li siwo kpɔa ŋusẽ ɖe dzesiawo dzia?

Ẽ, wò dzesiwo ate ŋu atrɔ le ɣeyiɣi aɖe megbe. Nulɔdɔ ate ŋu asẽ wu alo adze egɔme enuenu ne ʋetsuvi yeye aɖe ɖu wò. Le go aɖewo me la, nuwo abe ahanono, kamedede, kple kamedede ene hã ate ŋu akpɔ ŋusẽ ɖe alesi wò ŋutilã wɔa nui ɖe alpha-gal ŋu ​​dzi.

Nukatae Alpha-gal Dɔlélea didi sesẽ alea gbegbe?

Esia ate ŋu asesẽ vie be woade dzesii. Susu geɖewo tae.

Ðekae nye be ʋetsuviwo mesea veve ne woɖu wo o , eyata ame geɖe menya gɔ̃ hã be ʋetsuvi aɖe ɖu yewo o.

Azɔ hã, to vovo na nuɖuɖu ƒe nulɔdɔ bubuwo la, alesi wòwɔa nui ɖe alpha-gal ŋu ​​xɔa gaƒoƒo geɖe hafi wòdzea egɔme . Ɣeaɖewoɣi la, dzesiawo dzena le zã titina le fiẽnuɖuɖu vɔ megbe. Amekae asusu be lã si woɖuna le ŋdi me alo le ŋdɔnuɖuɣi tae?

Azɔ hã, menye ɣesiaɣi si woɖu alpha-gal la, nuwɔna aɖe nɔa eŋu o, eye dzesiawo hã medzena le mɔ ɖeka nu ɣesiaɣi o.

Le nu siawo ta la, ate ŋu asesẽ vie na wò kple wò ɖɔkta be miakpɔe ɖa be esia nye nu bubu aɖe si menye alpha-gal o hã.

Aleke tututu ɖɔktawo dea dzesi esia?

Be nànya AGS la, wò ɖɔkta alo nulɔdɔŋutinunyala alé ŋku ɖe wò dzesiwo, atikewɔwɔ ŋutinya, kple ŋutilãmedɔdada ŋu nyuie. Tsɔ kpe ɖe eŋu la, woate ŋu awɔ nulɔdɔ dodokpɔ atsɔ aɖo kpe dɔlélea dzi. Wo dometɔ vevitɔwo dometɔ aɖewoe nye:

• Ʋudodokpɔ: Esia léa ŋku ɖe immunoglobulin-E dɔlékuiwutikewo (IgE) le ʋua me, si míaƒe dɔlélenutsiŋutete wɔna ɖe alpha-gal ŋu ​​hã.
• Ŋutilã ƒe ƒoƒo dodokpɔ: Le esia me la, wotsɔa nusi nana ŋutilãa melɔ̃a nu le ame ŋu ƒe akpa sue aɖe dana ɖe ŋutigbalẽa ƒe gowo dzi be woakpɔe ɖa be nu aɖe le eŋu hã.

Ne èsusu be AGS ate ŋu anɔ ye ŋu la, yi ɖɔkta gbɔ kaba ale si nàte ŋui. Zi alesi nète ŋu de dzesii kaba la, zi nenemae wòanɔ bɔbɔe be nàƒo asa na nusiwo nana ame ƒe ŋutilã melɔ̃a nu o eye nàxe mɔ ɖe kuxiwo nu.

Ðe atike blibo aɖe li na esia?

Abe alesi míegblɔe va yi ene la, fifia la, womekpɔ atike aɖeke na Alpha-gal Syndrome o. Gake mègatsi dzi o. Ne wokpɔe kaba la, mia kple wò ɖɔkta miate ŋu awɔ dɔ aduadu awɔ ɖoɖo ɖe dɔdzikpɔkpɔ ŋu si asɔ na wò hiahiãwo.

Aleke wowɔa nu ɖe ​​esia ŋui?

Atike vevitɔ si woate ŋu azã na amesi ŋu AGS le enye be wòaƒo asa na nuɖuɖu kple nusiwo me alpha-gal le keŋkeŋ . Tsɔ kpe ɖe eŋu la, wonaa atikewo be woatsɔ aɖu dzesiawo dzi ne woɖu nane si le abe esia ene le vo me.

Ðɔktawo ate ŋu akafu atikewo abe antihistamines alo adrenaline injector ene na zazã kpata. Le dɔléle sesẽwo abe anaphylaxis ene me la, epinephrine-tike sia ate ŋu axɔ ame ɖe agbe. Atikewɔwɔ bubuwo nɔ te ɖe wò dzesiwo dzi. Le kpɔɖeŋu me, cromolyn-tike si woano ate ŋu akpe ɖe nuɖuɖumeŋusẽ ƒe kuxiwo ŋu.

Aleke mawɔ aɖe afɔku si le Alpha-gal Syndrome xɔxɔ me dzi akpɔtɔ?

Mɔ nyuitɔ si dzi nàto akpɔ ɖokuiwò ta tso menye AGS ɖeɖeko me o, ke boŋ tso dɔléle bubu siwo ʋetsuviwo hena vɛ hã me enye be nàƒo asa na ʋetsuviwo ƒe ɖuɖu . Nu geɖe li nàte ŋu awɔ atsɔ awɔ esia:

• Ƒo asa na teƒe siwo ʋetsuviwo le: Ƒo asa na azɔlizɔzɔ madzemadzee le avewo, gbewo, kple teƒe siwo atiwo sɔ gbɔ ɖo, vevietɔ le afisiwo lãwo le. Kpɔ nyuie hã ne èle dɔ wɔm le abɔ me.
• Kpɔ eta nyuie: Do awu siwo ƒe abɔwo didi, pantalon legbewo. De soxwo wò pantalon dzi, do afɔkpa. Ne anya wɔ la, zã kposɔ kple asigɛ.
• Zã nudzodzoeviwutikewo: Zã nudzodzoeviwutike si dzi atikewɔlawo da asi ɖo. Woate ŋu atsɔ ɖewo ade awudodo me. Woate ŋu atsɔ atike siwo me permethrin le asisi ɖe awuwo ŋu.
• Kpɔe ɖa be ʋetsuviwo hã le eme hã (Tick check):Ne ètrɔ gbɔ tso gota vɔ la, lé ŋku ɖe ɖokuiwò kple wò aƒemelãwo ŋu be ʋetsuviwo le wo me hã. Enyo hã be nàle tsi.
• Ne èkpɔ ʋetsuvi aɖe la, ɖee ɖa kaba: Zã aŋenu nàtsɔ alé ʋetsuvi la ƒe ta alo nu, eye nàhee nyuie ayi dzi evɔ màgbãe o. Emegbe nàsi dɔlékuiwutike aɖe ɖe teƒea.

Ne Alpha-gal Syndrome le ŋuwò la, nuɖuɖu, nunono, kple atike kawoe wòle be nàƒo asa na?

Ele be ame geɖe siwo ŋu AGS le naƒo asa na lã dzĩ kple lã dzĩ ƒe atikewo keŋkeŋ. Gake menye amesiamee wɔa nu ɖe ​​alpha-gal ŋu ​​le mɔ ɖeka nu o. Eyata anyo wu be nàƒo nu kple wò ɖɔkta alo nulɔdɔŋutinunyala be nànya nusi tututu ʋãa wò.

Nusiwo wòle be woaƒo asa na zi geɖee nye:

• Lã dzĩ: nyilã, alẽvi, gbɔ̃, lãlã, avugbɔ̃e, nyitsu, haƒoƒo.
• Nusiwo wotsɔ lã dzĩ wɔe: nuɖuɖu siwo wotsɔ kpe ɖe nuɖuɖu ŋu, notsi, kreme, ice cream, lã ƒe ami (lard), cheese.
• Atike siwo wotsɔ léa ŋutigbalẽe si wotsɔ lã wɔe: nusiwo me collagen, lanolin, gelatin, glycerin le.
• Atike bubuwo: Ƒo nu kple wò ɖɔkta tso atike ɖesiaɖe si nàno ŋu. Azɔ hã, dzitodzito me ʋuka siwo tso ha alo nyiwo gbɔ, amekoko ƒe lãgbalẽ, kple atike aɖewo ate ŋu ana nulɔdɔ nadze ame dzi.

Nukae adzɔ emegbe? Aleke míanɔ agbe kple esia?

Ne èwɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi nyuie eye nèƒo asa na nusiwo hea wò nulɔdɔ vɛ la, àte ŋu anɔ agbe nyuie kple AGS. Wò ɖɔkta akpe ɖe ŋuwò nàdi mɔ siwo dzi nàto aɖe wò nulɔdɔ ƒe afɔkua dzi akpɔtɔ.

Nu vevitɔ kekeakee nye be nàɖe afɔ aɖewo atsɔ aƒo asa na ʋetsuviwo ƒe ɖuɖu bubuwo , elabena ʋetsuviwo ƒe ɖuɖu enuenu ate ŋu ana nulɔdɔa nagagblẽ ɖe edzi.

Ɣekaɣie wòle be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo?

Ne AGS ƒe dzesiwo dze ŋuwò la, yi nulɔdɔŋutinunyala alo atikewɔla si kpɔa dɔlélewo gbɔ enumake ale be woate ŋu awɔ atikewɔwɔ ƒe ɖoɖo si sɔ na wò.

Gbedasi si Wotsɔ Yi Aƒeme

Enyo, eyata Alpha-gal Syndrome (AGS) si ŋu míeƒo nu tsoe egbea nye lã dzĩ ƒe nulɔdɔ sesẽ si ʋetsuviwo ƒe ɖuɖu hena vɛ. Ate ŋu asesẽ vie be woakpɔ dɔlélea, elabena dzesiawo dzena le gaƒoƒo aɖewo megbe. Eye fifia la, atike aɖeke meli si woatsɔ adae o.

Gake mègatsi dzi o! Ne èkpɔe dze sii kaba, wɔ ɖe wò ɖɔkta ƒe aɖaŋuɖoɖo dzi, ƒo asa na nuɖuɖu kple atike siwo gblẽa nu le ame ŋu, eye nèkpɔ ɖokuiwò ta tso ʋetsuviwo si me la, wò hã àte ŋu anɔ lãmesẽ me ahanɔ lãmesẽ me. Ne dzesi siawo le ŋuwò la, kpɔ egbɔ be yeyi ɖɔkta gbɔ.

`Alpha-gal Syndrome, Lã dzĩ ƒe nulɔdɔ, Dɔléle siwo tso ʋetsuviwo gbɔ, Nuɖuɖu ƒe nulɔdɔ, Nulɔdɔ ƒe dzesiwo, Takpɔkpɔ tso ʋetsuviwo gbɔ