Mina míasrɔ̃ nu tso C-Peptide Dodokpɔa ŋu. Nukatae esia le vevie na wò amesiwo ŋu suklidɔ le?

Ðe suklidɔ le ŋuwòa? Alo ɖe wò ɖɔkta gblɔ na wò be nàwɔ dodokpɔ aɖe si woyɔna be C-Peptidea? Ne èse ŋkɔ sia la, ɖewohĩ vɔvɔ̃ ɖo wò vie eye nàdi be yeanya nu tso eŋu. "Nukae nye dodokpɔ yeye sia? Nukae wòdi?" Ðewohĩ èle tame bum. Gake mègatsi dzi kura o. Esia nye dodokpɔ bɔbɔe aɖe ŋutɔ si naa nyatakaka vevi geɖe mí be míatsɔ akpɔ wò suklidɔa gbɔ. Egbea, míaƒo nu tso C-Peptide dodokpɔ sia ŋu tsitotsito, le mɔ si gɔme nàte ŋu ase bɔbɔe ŋutɔ nu.

Kpuie ko la, nukae nye C-peptide?

Be míase esia gɔme la, mina míabu eŋu ale. Dɔgbo si le míaƒe ŋutilã me le abe dɔwɔƒe sue aɖe ene. Nu vevitɔ si dɔwɔƒe sia wɔnae nye lãmetsi aɖe si woyɔna be insulin . Insulin nye lãmetsi vevi aɖe ŋutɔ si kpɔa sukli (glucose) ƒe agbɔsɔsɔ si le míaƒe ʋu me dzi eye wòkpena ɖe míaƒe ŋutilã ƒe lãmenugbagbeviwo ŋu be woazã sukli ma abe ŋusẽ ene.

Fifia ne dɔgboa wɔ insulin sia la, eɖea akpa sue aɖe si lé ɖe eŋu hã ɖe go. Akpa mae nye nusi míeyɔna be C-peptide . Ne míagblɔe tututu la, insulin molecule aɖe dzɔna tso molecule gã aɖe si woyɔna be ‘proinsulin’ me. Ne woɖe insulin ƒe akpaa ɖa tso esia gbɔ eye woɖee ɖe go yi ʋua me la, C-peptide ƒe akpa si susɔ hã dona ɖe ʋua me.

Nu vevitɔe nye be ɣesiaɣi si insulin molecule aɖe do le dɔgboa me la, C-peptide ƒe agbɔsɔsɔ si sɔ hã dona. Ema fia be ne míedzidze C-peptide ƒe agbɔsɔsɔ si le ame ƒe ʋu me la, míate ŋu anya insulin agbɔsɔsɔme si tututu woawo ŋutɔ ƒe ŋutilã, si nye woawo ŋutɔ ƒe dɔgbo, le wɔwɔm. Esiae nye asixɔxɔ gãtɔ kekeake si le dodokpɔ sia ŋu.

Nukatae ɖɔkta aɖe abia tso asiwò be nàwɔ dodokpɔ sia?

Susu geɖe li siwo ta wò ɖɔkta ate ŋu akafu dodokpɔ sia ɖo. Ele abe kpeɖodzi vevi aɖe na ʋɔnudrɔ̃la si le dɔléle aɖe me kum ene.

• Kpɔ suklidɔ ƒomevi si le ŋuwò ɖa: Suklidɔ ƒomevi vevi eve li, suklidɔ Ƒomevi 1 kple suklidɔ Ƒomevi 2 . Dɔ ƒomevi eveawo wɔa dɔ le ŋutilãa me le mɔ vovovowo nu.
• Le suklidɔ Ƒomevi 1 me la , ŋutilãa ƒe dɔlélenutsiŋutete gblẽa lãmenugbagbevi siwo wɔa insulin le dɔgboa me. Esia wɔnɛ be ŋutilãa mewɔa insulin aɖeke kloe o. Eyata ne èlé ŋku ɖe ame ma tɔgbe ƒe C-peptide ƒe agbɔsɔsɔ ŋu la, aɖiɖi ŋutɔ.Alo ate ŋu anye zero.
• Le suklidɔ Ƒomevi 2 lia me la , togbɔ be dɔgboa wɔa insulin nyuie le gɔmedzedzea me hã la, ŋutilãa ƒe lãmenugbagbeviwo mewɔa nu nyuie ɖe insulin ma ŋu o (insulin ƒe tsitretsitsi). Emegbe, dɔgboa wɔa insulin geɖe wu tsɔ xea fe si mesɔ gbɔ o la teƒe. Eyata le suklidɔ Ƒomevi 2 le amesi ŋu suklidɔ Ƒomevi 2 le ƒe gɔmedzedze la, C-peptide ƒe agbɔsɔsɔ ate ŋu anɔ abe alesi wòle ene alo asɔ gbɔ .

• Dzidze alesi atikewɔwɔa kpɔ dzidzedzee: Ne èle suklidɔ ƒe atikewo zãm la, dodokpɔ sia ate ŋu akpɔe ɖa be atike mawo le wò dɔgboa ʋãm eye wòle insulin wɔm nyuie hã.

• Kpɔe ɖa be ehiã be woado insulin na wò hã: Vevietɔ ne suklidɔ Ha 2 lia le ŋuwò ɣeyiɣi didi aɖe la, wò dɔgbo ate ŋu agbɔdzɔ vivivi eye wòadzudzɔ insulin wɔwɔ. Ɣemaɣi la, wò C-peptide ƒe agbɔsɔsɔ aɖiɖi vivivi. Ɣemaɣie wò ɖɔkta atso nya me be ɣeyiɣia de be nàdze insulin dodo gɔme tso egodo.

• De vovototo insulin si ŋutilãa wɔna kple insulin si wodona dome: Esia nye nya vevi aɖe ŋutɔ. Tsɔe be ame si zãa insulin ƒe atikewoe nènye. Ne míelé ŋku ɖe insulin ƒe agbɔsɔsɔ si le wò ʋu me ŋu la, eɖea insulin si wò ŋutilã wɔna kple insulin si nèdona siaa fiana. Gake C-peptide ya mele nenema o. C-peptide mele insulin si dona tso gota me o. Eyata ne èlé ŋku ɖe C-peptide ƒe agbɔsɔsɔ ŋu la, àte ŋu anya insulin agbɔsɔsɔme si wò ŋutilã gakpɔtɔ le wɔwɔm nyuie, ne èle atikewo dom gɔ̃ hã.

• Di nusi gbɔ sukli ƒe agbɔsɔsɔ si medea ame dzi le o (hypoglycemia): Ame aɖewo ƒe ʋumesukli ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna le mɔ si me afɔku le nu. Dodokpɔ sia kpena ɖe ame ŋu be woanya nenye be insulin ƒe agbɔsɔsɔ fũ le ŋutilã me gbɔe nusi gbɔ wòtso alo nu bubu aɖe si gbɔ wòtso.

Alesi woawɔ dodokpɔa ahadzra ɖoe

Mehiã be nàvɔ̃ dodokpɔ sia wɔwɔ o. Enye ɖoɖo bɔbɔe aɖe ŋutɔ.

Aleke nèwɔa dodokpɔae?

Zi geɖe la, esia bia be woaɖe ʋu . Abe alesi wowɔa ʋudodokpɔ edziedzi ene la, dɔnɔdzikpɔla alo dodokpɔxɔ me dɔwɔla aɖe axɔ ʋu sue aɖe tso ʋuka aɖe si le wò alɔnu me. Ase le eɖokui me abe ƒoƒo sue aɖe ene, abe anyidi ɖum ene, ema koe nye ema.

Ƒã ŋutɔ hafi woate ŋu atsɔ aɖuɖɔtoe awɔ dodokpɔ sia . Le nɔnɔme mawo me la, zi geɖe la, ehiãna be woaɖe aɖuɖɔ gaƒoƒo 24. Wò ɖɔkta alo nudokpɔƒea ana mɔfiamewo kple nugoe si nàtsɔ awɔ esia wò.

Ðe wòhiã be nàdzra ɖo hafi adze dodokpɔa gɔmea?

Ẽ, ɣeaɖewoɣi la, ate ŋu ahiã be míadzra ɖo vie.

• Nutsitsidɔ: Wò ɖɔkta ate ŋu abia tso asiwò be nàtsri nuɖuɖu alo nunono gaƒoƒo 8 va ɖo 12 hafi woawɔ dodokpɔa. Gake zi geɖe la, womedea se ɖe tsinono nu o.
• Dodokpɔ le dzideƒoname megbe:Ɣebubuɣiwo la, wò ɖɔkta ate ŋu adi be nàɖu nane (nane si me sukli le) eye nàlé ŋku ɖe wò C-peptide ƒe agbɔsɔsɔ ŋu ne wodo ŋusẽ wò dɔgboa vɔ. Eyata wɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi nyuie ɣesiaɣi.
• Atikewo: Ne èle atike aɖewo zãm na dɔléle bubuwo la, kpɔ egbɔ be yegblɔ wo na wò ɖɔkta. Atike aɖewo ate ŋu akpɔ ŋusẽ ɖe dodokpɔ sia me tsonu dzi, eyata woate ŋu abia tso asiwò be nàdzudzɔ wo nono hena ɣeyiɣi aɖe ŋkeke ɖeka alo eve do ŋgɔ na dodokpɔa.

Afɔku gã aɖeke mele dodokpɔ sia me o. Àte ŋu akpɔ abi aɖewo ne woɖe ʋua, gake esia nu ayi le ɣeyiɣi aɖe megbe.

Nukae dodokpɔa me tsonu gblɔ?

Mègana xexlẽdzesi siwo le wò dodokpɔ ŋuti nyatakakaa dzi navɔ̃ o. Wò ɖɔkta koe ate ŋu aɖe emetsonuwo gɔme nyuie, elabena ele be woatsɔ wo asɔ kple nu bubuwo, abe sukli ƒe agbɔsɔsɔ le ʋu me kple atike siwo zãm nèle ene.

C-peptide ƒe agbɔsɔsɔ si bɔ dometɔ aɖewoe nye esi. Gake nenɔ susu me na wò be dzidzenu siawo ate ŋu ato vovo vie tso dodokpɔxɔ ɖesiaɖe me.

Ne C-peptide ƒe agbɔsɔsɔ le sue (Low C-peptide) .

Ne wò C-peptide ƒe agbɔsɔsɔ mede esi sɔ o la, efia be insulin ʋɛ aɖewo koe wò dɔgboa le wɔwɔm alo mele ewɔm kura o.

Tsɔ kpe ɖe eŋu la, nɔnɔme bubu siwo ate ŋu ana C-peptide ƒe agbɔsɔsɔ naɖiɖi dometɔ aɖewoe nye:

• Suklidɔ Ƒomevi 2 si nɔa anyi ɣeyiɣi didi aɖe: Ne suklidɔ Ha 2 lia le ŋuwò ƒe geɖe la, ɖeɖi ate dɔgboa ŋu eye insulin ƒe wɔwɔme ate ŋu aɖe akpɔtɔ.
• Addison ƒe dɔléle: Nɔnɔme si me adrenal glands ƒe dɔwɔwɔ me gblẽna le.
• Aklãdɔléle.
• Insulin dodo: Insulin nono le gota ate ŋu atɔ te ŋutilãa ƒe insulin wɔwɔ.

Ne C-peptide ƒe agbɔsɔsɔme sɔ gbɔ (High C-peptide) .

Ne wò C-peptide ƒe agbɔsɔsɔ sɔ gbɔ wu esi sɔ la, efia be wò dɔgbo le dɔ wɔm akpa eye wòle insulin wɔm fũ akpa.

Tsɔ kpe ɖe eŋu la, nɔnɔme bubu siwo ate ŋu ana C-peptide nasɔ gbɔ ɖe eme dometɔ aɖewoe nye:

• Insulin ƒe dɔlélenutsiŋutete: Woate ŋu akpɔe le do ŋgɔ na suklidɔ hã me.
• Cushing syndrome: Nɔnɔme si me ŋutilãa wɔa lãmetsi si nye cortisol fũ akpa.
• Ayiku ƒe dɔmawɔmawɔ nyuie: Ne ayikuawo mete ŋu ɖe C-peptide ɖa nyuie o la, eƒe agbɔsɔsɔ le ʋua me dzina ɖe edzi.
• Insulinoma: Dɔdzẽ ƒomevi aɖe si mebɔ kura o si naa insulin si sɔ gbɔ wu.
• Potassium ƒe agbɔsɔsɔ si dzi ɖe kpɔtɔ le ʋu me (Hypokalemia).

Nuka kee ado tso eme o, wò ɖɔktae ana gɔmesese si de pɛpɛpɛ wu kple afɔɖeɖe siwo kplɔe ɖo na wò. Eyata kpɔ egbɔ be yexɔ nyatakakaa eye yeakpɔe.