Ðe dzesi siawo le viwò suea ŋua? - Mina míasrɔ̃ nu tso Embryonic Tumors ŋu

Ðe ta ɖua viwòa zi geɖea? Alo ɖe nède dzesi tɔtrɔ aɖewo le viwò suea ƒe tsitsi mea? Ɣeaɖewoɣi la, nusiawo ate ŋu anye nusiwo sɔ. Gake ɣeaɖewoɣi la, nane ate ŋu anɔ megbe na wo si hiã be woatsi dzi vie. Egbea míele nu ƒom tso nɔnɔme aɖe si ate ŋu ava ɖevi mawo tɔgbe ŋu, gake míese nu geɖe tso eŋu o, eye ate ŋu anye nu sesẽ vie. Emae nye fugboe ƒe dɔdzẽ, alo `(Embryonal Tumors)`. Mègatsi dzi o, míaƒo nu tso nusianu ŋu le mɔ bɔbɔe aɖe nu.

Nukawoe nye fugboe ƒe dɔdzẽ siawo? Mina míase egɔme tututua?

Kpuie ko la, fugboe ƒe dɔdzẽ nye ahɔhɔ̃ me dɔdzẽ si dona tso lãmenugbagbevi siwo le tsitsim kabakaba me. Lãmenugbagbevi siawo tsoa lãmenugbagbevi siwo susɔ tso esime ɖevi nɔ vidzidɔ me, si fia be le fugboe ƒe nɔnɔme me. Fugboe ƒe lãmenugbagbevi siawo, siwo woyɔna be ``Embryonic cells,`` wɔa dɔ vevi aɖe ŋutɔ le ɖevi ƒe ŋutilã ƒe tsitsi ƒe gɔmedzedze. Gake ɣeaɖewoɣi la, le ɖevia dzidzi vɔ megbe gɔ̃ hã la, fugboe me lãmenugbagbevi siawo dometɔ aɖewo te ŋu nɔa ahɔhɔ̃a me. Lãmenugbagbevi siawo siwo susɔ lae dzea tsitsi gɔme zua fugboe ƒe dɔdzẽ.

Dɔdzẽ siawo gblẽa nu le ɖeviwo ŋu wu. Wo dometɔ aɖewo nye kansa, si fia be woate ŋu anye afɔku (nu vɔ̃ɖi). Bubuwo menye kansa o, si fia be woate ŋu anye esiwo me nuvevi aɖeke mele o (siwo me dɔlékui aɖeke mele o). Zi geɖe la, wova nɔa ahɔhɔ̃a me. Woate ŋu ado ɖe aklãa ŋu hã ɣeaɖewoɣi. Nusi me afɔku le wue nye be dɔdzẽ siawo ate ŋu akaka to ahɔhɔ̃meka (CSF), si nye tsi si le abe tsi ene si ƒo xlã ahɔhɔ̃ kple aklã me. Afɔku ƒomevi siwo me afɔku le wu ate ŋu akaka kabakaba ŋutɔ eye woate ŋu ade ame ƒe agbe afɔku me.

Wò ɖɔkta ateŋu ayɔ fugboe ƒe dɔdzẽ siawo hã alo ``Embryomas.'' Tsã la, woyɔa esiawo be ``Primitive Neuroectodermal Tumor (PNET)''.

Ðe fugboe me kansa ƒomevi aɖewo lia? Nukawoe wonye?

Ẽ, fugboe me dɔdzẽ siawo hã ma ɖe ƒomevi vovovowo me. Woyɔa ƒomevi si bɔ wu be ``Medulloblastoma.`` Esia dzɔna le akpa aɖe si woyɔna be ``Cerebellum.`` Eyae nye be, le megbe, viwò ƒe ahɔhɔ̃ ƒe akpa si le ete.

Fugboe ƒe dɔdzẽ ƒomevi bubuwo li siwo menye ``Medulloblastoma'' o. Woawoe nye:

• `(Atypical teratoid/rhabdoid tumor - AT/RT)`: Esia hã dzɔna le ahɔhɔ̃mekawo me (ahɔhɔ̃a ƒe megbe).
• `(Embryonal tumor with multilayered rosettes - ETMRs)`: Woda esia ɖe hatsotso me be `(C19MC-trɔ)` alo `(NOS - womegblɔe bubui o)`. Etsina le `(Cerebrum)` (si fia be akpa gãtɔ le ahɔhɔ̃a tame kple ŋgɔgbe) kple aklã me.
• `(Medulloepithelioma)`: Esia dzɔna le ahɔhɔ̃, aklã, kple lãmeka siwo le aklã godo me. Esiawo nye kansa siwo tsina kabakaba ŋutɔ, siwo nu sẽna ŋutɔ. Zi geɖe la, wova nɔa ɖevi sue ŋutɔwo me, eye mɔnukpɔkpɔ si li be woahaya la medea ame dzi o.
• Central nervous system neuroblastoma: Esia dzɔna le lãmeka siwo ƒo xlã ahɔhɔ̃ kple aklã ƒe ƒuƒoƒo me kpakple ahɔhɔ̃meka siwo le ahɔhɔ̃mekawo me.
• `(Cribriform ahɔhɔ̃mekawo ƒe dɔdzẽ)`:Esia dzɔna le do siwo me tsi yɔ fũu (ventricles) siwo le ahɔhɔ̃a me la me.

Aleke gbegbee kansa siawo bɔe? Amekae ate ŋu axɔ wo wu?

Le United States ƒe akɔntabubu nu la, fugboe ƒe dɔdzẽ siawo nye ahɔhɔ̃ me dɔdzẽwo katã ƒe 12% lɔƒo le ɖevi siwo xɔ tso ƒe 0 va ɖo ƒe 14. Le wo dome la, ƒomevi si ŋu míeƒo nu tsoe va yi, ``Medulloblastoma``, ye bɔ ​​wu - si fia be, fugboe ƒe dɔdzẽwo katã ƒe 68% kple edzivɔ. ``Atypical teratoid/rhabdoid tumors - AT/RT`` nye abe 17% ene.

Kansa siawo bɔ ɖe vidzĩwo kple ɖevi suewo me wu. Togbɔ be woate ŋu adzɔ le ame tsitsiwo me hã la, womebɔ o. Le kpɔɖeŋu me, ƒomevi `(AT/RT)` bɔ ɖe ŋutsuvi siwo mexɔ ƒe 3 haɖe o me wu. `(ETMRs)` ƒomevi bɔ ɖe nyɔnuvi siwo mexɔ ƒe 4 haɖe o me wu.

Nukae nye fugboe me kansa ƒe dzesiwo? Kpɔe ɖa be nusiawo le viwòa ŋu hã

Ahɔhɔ̃ me dɔdzẽ ƒe dzesiwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ. Wonɔ te ɖe ƒe si ɖevia xɔ, dɔdzẽ ƒomevi si le eŋu, kple afisi wòle le ahɔhɔ̃a me dzi. Gake dzesi aɖewo li siwo bɔ siwo woate ŋu akpɔ:

• Taɖuame, vevietɔ le ŋdi me.
• Aɖuɖɔtoe kple ʋuʋudedi.
• Ðeɖiteameŋu, ɖeɖiteameŋu, kple alɔ̃dɔdɔ ɣesiaɣi.
• Nukpɔkpɔ ƒe gbɔdzɔgbɔdzɔ (e.g. nukpɔkpɔ si me kɔ o, nukpɔkpɔ eve).
• Alɔ̃madɔmadɔ.

Bu eŋu kpɔ, viwò suea mele du dzi le fefem abe tsã ene o, ele gbɔgblɔm ɣesiaɣi be "Dada, nye ta le veve sem," eye ɣeaɖewoɣi la, eɖea aɖuɖɔ ne efɔ le ŋdi me ko. Ne nusiawo yi edzi la, ele be nàkpɔ ɖɔkta godoo.

Woate ŋu akpɔ dzesi siwo gbɔna le vidzĩwo hã ŋu:

• Ta la lolona ɖe edzi ne ame tsi.
• Nuwɔna ƒe tɔtrɔ (e.g., avifafa enuenu, dzikudodo, dzimaɖitsitsi).
• Dadasɔ ƒe bubu ne èle azɔli zɔm alo le du dzi, abe nuwɔwɔ aduadu ƒe anyimanɔmanɔ ene.
• Nuɖuɖu nyuie maɖumaɖu nye nunyuimakpɔɖu ƒe dzesi.
• Tsitsi ƒe nu vevi siwo sɔ ɖe ƒexɔxɔ nu gbɔ ɖoɖo (e.g., anyinɔƒe, tsitretsitsi, alo nuƒoƒo le mɔ si sɔ ɖe ƒexɔxɔ nu nu mawɔmawɔ).

Nukatae fugboe me dɔdzẽ sia dzea ame dzi? Nuka gbɔe wòtso?

Kansa dzɔna ne lãmenugbagbeviwo tsi hemã le mɔ si mesɔ o nu, wu alesi wòle be woanɔ. Gake numekulawo meka ɖe nusita fugboe me lãmenugbagbevi siawo siwo susɔ la trɔna zi ɖeka zua fugboe ƒe dɔdzẽwo dzi haɖe o.

Ðe afɔku aɖewo li siwo gblẽa nu le kansa sia ƒe dzɔdzɔ ŋua?

Ẽ, domenyiŋusẽfianu aɖewo ate ŋu ana viwòa naxɔ fugboe me kansa ƒomevi aɖe si woyɔna be ``Medulloblastoma.'' Nɔnɔme mawo dometɔ aɖewoe nye:

• `(Turcot ƒe dɔléle)`
• `(Rubinstein-Taybi ƒe dɔléle)`
• `(Gorlin ƒe dɔléle)`
• `(Li-Fraumeni ƒe dɔléle)`
• `(Fanconi ʋusɔgbɔdɔ)`

Esiawo nye nɔnɔme siwo mebɔ kura o, gake ne dɔléle sia le wò ƒomea me la, ele vevie be nàgblɔe na wò ɖɔkta.

Kuxi kawoe ate ŋu ado tso fugboe me kansa me? Ðe wònye afɔkua?

Kuxi siwo fugboe me kansa hena vɛ ate ŋu ade ame ƒe agbe afɔku me ɣeaɖewoɣi. Eyata ele vevie ŋutɔ be míanya esia. Kuxi vevi siwo woate ŋu akpɔe nye:

• Hydrocephalus nye nɔnɔme si me tsi yɔa ahɔhɔ̃a me fũ eye eƒe nyaƒoɖeamenu dzina ɖe edzi. Esia ate ŋu agblẽ nu le ahɔhɔ̃a ŋu.
• Ahɔhɔ̃ ƒe gbegblẽ.
• Sidzedze ƒe dɔmawɔmawɔ nyuie - Esia fia be ekpɔa ŋusẽ ɖe ŋutete si le ame si be wòabu tame ahasrɔ̃ nu ŋu.
• Tɔtrɔ siwo vaa lãmetsiŋusẽ ƒe dɔwɔwɔ me (Endocrinopathies).

Aleke ɖɔktawo wɔa dea dzesi kansa sia ƒomevi? (Dɔléle ƒe dzesi) .

Ne dzesi siwo ŋu míeƒo nu tsoe va yi la dometɔ aɖe le viwò ŋu, alo ne ètsi dzi ɖe viwòa ƒe lãmesẽ ŋu la, yi viwòa ƒe ɖɔkta enumake. Ðɔkta ate ŋu anya fugboe ƒe kansa ne edo viwòa kpɔ eye wòwɔ dodokpɔ siwo hiã.

Ðɔktaa abia nya wò tso viwòa ƒe dzesiwo, eƒe lãmesẽ ŋutinya, kple nenye be wò ƒomea me tɔ aɖe xɔ dɔléle sia tɔgbe kpɔ hã.

Dodokpɔ siwo wowɔna tsɔ ɖoa ​​kpe dɔlélea dzi pɛpɛpɛe nye:

• MRI-dɔdamɔnu aɖe.
• `(CT)` ƒe nɔnɔmetata aɖe.
• Akɔta ƒe dodo nye dɔdamɔnu si me woɖea tsi sue aɖe le akɔta. Woate ŋu azã esia hã atsɔ akpɔe ɖa be kansadɔlékuiwo kaka hã.
• Lãmetsi sue aɖe ɖeɖe tso dɔdzẽa me kple edodokpɔ (Biopsy). Esiae na míete ŋu nya kansa ƒomevi si tututu wòle.

Nukae nye esia ƒe atikewɔwɔ? Ðe ɖevia ahayaa?

Atikewɔwɔ na vidzidɔ me kansa toa vovo le nu geɖe nu, siwo dometɔ aɖewoe nye kansa ƒomevi, dɔdzẽa ƒe lolome, kple afisi wòle. Atikewɔwɔmɔnu siwo bɔ dometɔ aɖewoe nye:

• Amekoko si wowɔna tsɔ ɖea dɔdzẽa ɖae nye amekoko be woaɖe dɔdzẽa ɖa.
• Kekeli ƒe atikewɔwɔ.
• Atike siwo tsia kansa nu (Chemotherapy) nana.
• Targeted Therapy (atike siawo nye atike tɔxɛwo).

Zi geɖe la, viwòa ate ŋu ahiã atike siwo wu zi ɖeka. Le kpɔɖeŋu me, ɖɔktawo aɖe dɔdzẽa ɖa dedie alesi woate ŋui ne wowɔ dɔ nɛ. Emegbe, woate ŋu ana atikewɔmɔnu be woatsɔ awu kansadɔlékui ɖesiaɖe si susɔ alo be dɔdzẽa naɖiɖi ɖe edzi.

Wole numekuku geɖe wɔm tso fugboe me kansa sia ƒomevi ŋu, eye ɖewohĩ viwòa adze na dɔdamɔnu dodokpɔwo be woake ɖe atike yeyewo ŋu.

Enye nusi sɔ be nàse le ɖokuiwò me be nuteɖeamedzi kple nu te ɖe ye dzi le nuxaxaɣi sia me. Dzila geɖe kpɔnɛ be yewoate ŋu age ɖe kpekpeɖeŋunaha aɖe me alo aƒo nu kple tagbɔdɔléle ŋuti aɖaŋuɖola aɖe le ɣeyiɣi sesẽ sia me. Ðɔkta kple dɔnɔdzikpɔla siwo le viwòa dam hã afia alesi nàdo alɔ viwòa ahafa akɔ na wò le ɣeyiɣi sia me.

Ðe atikewɔwɔa ƒe nugbegblẽ aɖewo lia? Nukawoe wonye?

Ẽ, abe atikewɔmɔnuwo katã ene la, eƒe nugbegblẽ le ame ŋu ate ŋu anɔ anyi.

Nusiwo ate ŋu ado tso eme le amekoko megbe:

• Ʋu si le dodom.
• Ʋu ƒe sisi.
• Dɔdzedze.
• Lãmetsiŋusẽ ƒe gbegblẽ.

Kekeli kple atikewɔmɔnu ƒe nugbegblẽ siwo ate ŋu ado tso eme dometɔ aɖewoe nye (gake menye woawo koe o):

• Ɖeɖi te eŋu.
• Aɖuɖɔtoe kple ʋuʋudedi.
• Taɖa ƒe ŋeŋe.
• Ŋutilã ƒe nulɔdɔwo, ŋutigbalẽ ƒe amadede biã.
• Taɖuame.

Kansa aɖewo ate ŋu atrɔ ava ne woda wo heɖe wo ɖa gɔ̃ hã.

Nukae nye dɔlélea ƒe ŋgɔdonya?

Alesi viwòa ƒe dɔlélea azɔ, i.e. alesi wòanya wɔ be wòahaya kple ɣeyiɣi didi si wòaxɔ, nɔ te ɖe nu geɖe dzi, siwo dometɔ aɖewoe nye:

• Kansa ƒomevi.
• Afisi kansa la le.
• Eɖanye be kansa la kaka alo mekaka o.
• Ƒe si ɖevia xɔ.
• Amekoko alo atikewɔwɔ siwo wowɔ va yi me tsonu.
• Ðevia ƒe lãmesẽ bliboa.

Dɔlékui ƒe lãmenugbagbeviwo ƒe dɔdzẽ aɖewo wɔa adã ŋutɔ, wokakana bɔbɔe, eye woate ŋu atrɔ ava le atikewɔwɔ vɔ megbe gɔ̃ hã. Ame bubuwo ate ŋu anye ame siwo mewɔa nuvevi ame o. Viwò ƒe ɖɔktae nye ame nyuitɔ kekeake si agblɔ nusi ava dzɔ ɖi na wò.

Nya kae woate ŋu agblɔ tso ɖevia ƒe agbenɔƒe le nɔnɔme sia me ŋu?

Esesẽ be woana ŋuɖoɖo si ŋu kakaɖedzi le tso ɖevi siwo ŋu dɔléle sia le ƒe agbenɔƒe ŋu, elabena eto vovo. Le kpɔɖeŋu me, numekuku aɖe ka nya ta be ɖevi siwo ŋu Medulloblastoma le dometɔ siwo ade 33% kuna le kuxiwo ta. Le fugboe ƒe dɔdzẽ siwo nu sẽ wu abe ETMR ene gome la, agbenɔƒe le mama dedie nu le dɔlélea kpɔkpɔ vɔ megbe anɔ abe ɣleti 12 ene.

Gake viwòa ƒe agbenɔƒe ate ŋu ato vovo na ɖevi bubu siwo ŋu kansa ƒomevi ma ke le. Enɔ te ɖe nusiwo le abe dɔdzẽa ƒe lolome kple afisi wòle ene dzi. Viwòa ƒe atikewɔlawo ƒe ƒuƒoƒo ana nyatakaka yeyewo wò tso atikewɔwɔ ƒe mɔnuwo kple beléle nyuitɔ kekeake si li fifia si ate ŋu ana viwòa ƒe agbetsitsi ƒe mɔnukpɔkpɔ nanyo ɖe edzi ŋu.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne ède dzesi fugboe me kansa ƒe dzesi siawo dometɔ aɖe le viwòa ŋu , kpɔ egbɔ be yeyi ɖɔkta gbɔ:

• Ne tsitsime ƒe nu vevi siwo sɔ ɖe wò ƒexɔxɔ nu to ŋuwò.
• Ne tɔtrɔ gãwo va le nuwɔna me.
• Ne nuɖuɖu sesẽ na wò, ne nuɖuɖu megadzroa wò o.
• Ne dadasɔ ƒe kuxiwo le ŋuwò ne èle azɔli zɔm alo le du dzi.
• Ne èsena le ɖokuiwò me enuenu be yeƒe lãme le ʋuʋum alo le ʋuʋum.

Vevietɔ wu: Ne viwòa ƒe lãme gbã la, ƒo ka na 911 (alo wò nutoa me xexlẽdzesi kpata) enumake, alo nàkplɔ wo ayi kɔdzi ƒe dɔwɔƒe si te ɖe ŋuwò kpata enumake.

Nya vevi kawoe wòle be míabia ɖɔktaa?

Le ɣeyiɣi sia tɔgbe me la, biabia geɖe ate ŋu anɔ asiwò. Mègavɔ̃ be yeabia nusianu si le susu me na wò ɖɔkta o. Nya vevi aɖewo siwo nàte ŋu abiae nye esi:

• Afikae dɔdzẽa le?
• Atikewɔwɔ ka ƒomevie nèkafu?
• Nukawoe nye atikeawo ƒe nugbegblẽ le ame ŋu?
• Aleke mawɔ akpɔ vinye dzi le atikewɔwɔ sia me?
• Nukae nye vinye ƒe dɔlélea ƒe ŋgɔdonya (mɔnukpɔkpɔ be wòahaya)?

Gbedasi vevi aɖe na dzilawo (Take-Home Message) .

Enye nusi sɔ be vɔvɔ̃ naɖo wò, màte ŋu awɔ naneke o, eye nàtsi dzimaɖi ne èse be dɔdzẽ aɖe si ate ŋu awu viwòa le eƒe agbe afɔku me. Ate ŋu asesẽ be woado dzi be wòahiã be woawɔ dɔ na ɖevi eye woawɔ atike sesẽwo abe atikewɔmɔnu ene le eƒe ɖevime nenema gbegbe. Fafafa na ɖevi le ɣeyiɣi sia tɔgbe me ate ŋu asesẽ ŋutɔ.

Gake ɖo ŋku esia dzi: Togbɔ be kansa sia ƒomevi mebɔ o hã la, atikewɔlawo ƒe ƒuƒoƒo si le viwòa dam la xɔ hehe nyuie eye nuteƒekpɔkpɔ geɖe su wo si. Woawɔ nusianu si woate ŋui be woaɖe kuxiwo kple atikewɔwɔ ƒe nugbegblẽ le ame ŋu dzi akpɔtɔ, eye woana akɔfafa kple beléle si viwòa hiã le mɔzɔzɔ sesẽ sia me.

Ne mèka ɖe nusi nàwɔ alo alesi nàkpe ɖe viwòa ŋu dzi o la, ƒo nu kple viwòa ƒe ɖɔktawo. Woate ŋu aɖe viwòa ƒe nɔnɔme kple etsɔme mɔkpɔkpɔ me na wò. Woate ŋu afia asi nu bubuwo hã wò, abe nuƒoƒo kple susumedɔléle ŋuti aɖaŋuɖola alo gege ɖe kpekpeɖeŋunaha aɖe me ene.

Le ɣeyiɣi sia me la, akpe ɖe ŋuwò ŋutɔ ne èƒo xlã xɔ̃wòwo kple ƒometɔ siwo dzi nèka ɖo eye nàte ŋu aƒo nu kplii.

` Fugboe ƒe Dɔdzẽ, Ahɔhɔ̃ me Dɔdzẽ, Ðevimenɔɣi ƒe Kansa, Kansa ƒe Dzesiwo, Kansa ƒe Atikewɔwɔ, Medulloblastoma