Ènya nu tso ŋusẽ gã sia si le wò ŋutilã me ŋua? Nusianu si ku ɖe Epinephrine / Adrenaline ŋu!

Ðe vɔvɔ̃ ɖo wò ŋutɔ alo ƒe mo wɔ yaa zi ɖeka kpɔa? Ɣemaɣi la, wò dzi nɔa ƒoƒom kabakaba, fifia nèɖea fifia, eye wò abɔwo kple afɔwo nɔa ƒoƒom. Egbea míele nu ƒom tso atike wɔnuku aɖe si wɔa dɔ le wò ŋutilã me ɣemaɣi ŋu. Enye epinephrine , alo abe alesi ɖewohĩ èse ene la , adrenaline . Esia nye nu vevi aɖe ŋutɔ le míaƒe ŋutilã me. Na míakpɔ nusi wònye kple alesi wòwɔa dɔe ɖa.

Nukae nye epinephrine? Nukatae woyɔe be adrenaline?

Kpuie ko la, epinephrine nye lãmetsiŋusẽ kple ahɔhɔ̃mekawo ƒe dɔwɔwɔ le míaƒe ŋutilã me. Abe lãmetsi ene la, míaƒe adrenal glands ye wɔae heɖenɛ doa goe . Esiawo le abe kpo eve siwo le míaƒe ayikuwo tame ene. Esi wònye ahɔhɔ̃mekawo ƒe dɔwɔwɔ ta la, ele abe atikewo ƒe dɔla ene. Ekpena ɖe ame ŋu wòtsɔa gbedasiwo tso lãmeka ƒe lãmenugbagbevi ɖeka me yia bubu me, tso lãmeka ƒe lãmenugbagbevi me yia lãkusi ƒe lãmenugbagbevi me.

Epinephrine nye míaƒe veveseseɖeamenu ƒe lãmekawo ƒe akpa aɖe . Esiae ʋãa míaƒe ŋutilã ƒe "avuwɔwɔ alo sisi" ƒe ŋuɖoɖo le afɔku alo vɔvɔ̃ɣiwo. Le atikewɔwɔ me la, woyɔa esia be nuteɖeamedzi sesẽ ƒe ŋuɖoɖo .

Atike sia si nye epinephrine le atikewo ƒe ƒuƒoƒo aɖe si woyɔna be catecholamines me, tsɔ kpe ɖe norepinephrine kple dopamine ŋu . Esia tso molecule ƒe wɔwɔme tɔxɛ si le wo me gbɔ. Abe lãmetsi ene la, epinephrine dona tso norepinephrine si le míaƒe adrenal glands me.

Nukae epinephrine wɔna le míaƒe ŋutilã me?

Abe ahɔhɔ̃mekawo ƒe dɔwɔwɔ ene la, akpa sue aɖe koe epinephrine wɔna. Wowɔnɛ le agbɔsɔsɔ sue aɖe ko me le míaƒe lãmekawo me. Gake ekpɔa ŋusẽ ɖe nuwo abe míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ , susu ƒe dɔwɔwɔ , susu ƒe dɔwɔwɔ , vɔvɔ̃, kple dzidzɔkpɔkpɔ dzi . Lãmetsi sia ƒe agbɔsɔsɔ si mesɔ o ate ŋu ana alɔ̃madɔmadɔ, dzimaɖitsitsi, ʋusɔgbɔdɔ, kple dɔlélenutsiŋutete naɖiɖi.

Gake epinephrine ƒe dɔ vevitɔ kple vevitɔ kekeakee nye abe lãmetsiŋusẽ ene. Ne míele nuteɖeamedzi aɖe me la, míaƒe adrenal glandwo ɖea epinephrine ɖa. Nuwɔna sia hea tɔtrɔ kpata geɖe vaa míaƒe ŋutilã me. Emae nye nusi míeyɔna be `aʋa-alo-sitsoƒe ƒe ŋuɖoɖo`.

Nukae nye ‘avuwɔwɔ alo sisi ƒe ŋuɖoɖo’ sia?

Bu eŋu kpɔ, esi nèle zɔzɔm le mɔa dzi la, kasia avu gã aɖe ti kpo va dze ŋuwò. Alo, ele be nàƒo nuƒo le ƒuƒoƒo gã aɖe ŋkume etsɔ ŋdi, eye eŋu bubu nana vɔvɔ̃ ɖoa wò, alo? Ðeko woyɔa alesi míaƒe ŋutilã wɔa nui ɖe nɔnɔme kpata, nuteɖeamedzi mawo ŋu be `avuwɔwɔ alo sisi ƒe ŋuɖoɖo.` Ŋkɔ sia tso nyametsotso eve siwo wòle be mía tɔgbuiwo nawɔ ne wodze ŋgɔ afɔku. Míewɔa avu kple afɔkua (wɔa avu) alo míesina le enu (dzodzo) .

Esiae nye nusi dzɔna le `aʋa-alo-sitsoƒe ƒe ŋuɖoɖo` me:

Gbã la, wò ahɔhɔ̃ dea dzesii be afɔku li. Emegbe lãmeka siwo le ahɔhɔ̃a ƒe akpa aɖe si woyɔna be hypothalamus ɖoa gbedasi aɖe to míaƒe aklã me yia ŋutilãa ƒe akpa mamlɛa. Ahɔhɔ̃meka si tsɔa gbedasi sia tso ahɔhɔ̃a me yia akpa siwo sɔ gbɔe nye norepinephrine , si woyɔna hã be noradrenaline .

Ahɔhɔ̃meka sia si nye norepinephrine zɔa mɔ yia ŋutinu kple lãkusi siwo gbɔna me, si wɔnɛ be wowɔa nu kabakaba abe:

• Ŋkuwo: Ŋkuawo ƒe ŋkumeɖobolowo lolona ɖe edzi. Esia wɔnɛ be kekeli geɖe gena ɖe eme, si wɔnɛ be nète ŋu kpɔa nusiwo ƒo xlã wò nyuie wu. Esia kpena ɖe ŋuwò nèsina le afɔku nu.
• Ŋutilã: Kasia ŋutigbalẽa zua ɣie. Esia le alea elabena wole gbɔgblɔm na ʋuka siwo naa ʋu na ŋutigbalẽa be woaɖo ʋu ɖe teƒe siwo hiãe wu, abe lãmekawo ene. Elabena lãmekawo hiã ŋusẽ hafi woate ŋu awɔ avu alo aƒu du.
• Dzi: Dzia ƒoa kabakaba eye wòsẽna ɖe edzi , si wɔnɛ be woate ŋu atsɔ ʋu si me ɔksidzin sɔ gbɔ ɖo ayi teƒewo abe lãmekawo ene. Ʋu ƒe sisi hã dzina ɖe edzi le ɣeyiɣi sia me.
• Lãmetsiwo: Lãmetsiwo xɔa ʋu kple ɔksidzin geɖe, si wɔnɛ be woate ŋu awɔ nu kple ŋusẽ kple ablaɖeɖe geɖe wu.
• Aklã: Glycogen si wodzra ɖo ɖe aklã me la trɔna zua sukli , si naa ŋusẽ bubu si ŋutilãa hiã.
• Yaƒoƒomɔ: Yagbɔgbɔ va dea to ɖe edzi eye wònɔa kabakaba wu. Yaƒoƒomɔ̃awo ʋuna nyuie wu. Esia wɔnɛ be ɔksidzin geɖe gena ɖe ʋua me, eye emegbe wòzɔa mɔ yia lãmekawo gbɔ.

Le ɣeyiɣi ma ke me la, ahɔhɔ̃meka si nye norepinephrine hã zɔa mɔ yia míaƒe adrenal glandwo me. Emegbe adrenal glandawo ɖea lãmetsi eve , siwo nye adrenaline (epinephrine) kple noradrenaline ( norepinephrine) ɖea ʋukawo me. Lãmetsiŋusẽ siawo toa ʋukawo me le ŋutilã bliboa me, trɔna yia míaƒe ŋkuwo, dzi, yaƒoƒomɔ̃wo, ʋuka siwo le ŋutigbalẽa me, eye wotrɔna yia adrenal glandwo gbɔ. Gbedasi sia gblɔ be, "Yi nuwɔna sia dzi vaseɖe esime afɔkua nawu enu."

Esia nye numeɖeɖe bɔbɔe ŋutɔ aɖe le `avuwɔwɔ alo dzodzo ƒe ŋuɖoɖo ŋu.` Elɔ míaƒe lãmekawo ƒe akpa bubuwo, kpakple ŋutinu bubuwo, lãmetsiwo, kple ahɔhɔ̃mekawo ƒe dɔwɔwɔ ɖe eme.

Aleke wozãa epinephrine abe atike ene?

Wozãa epinephrine si wowɔ hã abe atike ene. Wozãnɛ le nɔnɔmewo abe:

• Dzi ƒe dɔmawɔmawɔ nyuie / Dzitodzito me Gbugbɔgadzɔ (CPR): Epinephrine doa ŋusẽ dzia. Esia nye agbeɖela ne wole `CPR` wɔm.
• Ŋku ƒe dɔwɔwɔ: Ekpena ɖe ŋkume ƒe ŋkume ƒe ŋkume ƒe lolome ŋu le amekoko me.
• Septic shock: Esia nye nɔnɔme si me ʋu ƒe sisi dzi ɖena kpɔtɔna le dɔlékui sesẽ aɖe ta. Epinephrine kpena ɖe ame ŋu be ʋu ƒe sisi dzina ɖe edzi.
• Asrã: Eʋua yaƒoƒomɔ̃wo eye wòɖea yaƒoƒomɔ̃wo ƒe ʋuʋu dzi kpɔtɔna.
• Anaphylaxis: Esia nye nulɔdɔ sesẽ aɖe si ate ŋu awu ame . Le nɔnɔme mawo me la, epinephrine ye nye atike gbãtɔ si wozãna tsɔ naa lãmeka siwo le yaƒoƒomɔ̃wo me la naɖe dzi ɖi. Ðewohĩ èkpɔ nane abe `EpiPen` si wozã ene.

Ðe nugbegblẽ aɖewo li ne wole epinephrine zãm abe atike enea?

Ẽ, ame aɖewo ate ŋu akpɔ nugbegblẽ le ame ŋu ne wole epinephrine zãm abe atike ene, eɖanye aerosol (si wogbɔna) alo atike si wodona na wo o. Ne èkpɔ dzesi siawo dometɔ aɖe la, ele be nàyi atikewɔƒe enumake :

Nusi ate ŋu adzɔ le epinephrine si wogbɔna (aerosol) ŋu:

• Nulɔdɔ: ŋutigbalẽ ƒe ʋuʋu, ʋuʋudedi, aɖuɖɔtoe, mo, nuyi, alo aɖe ƒe vuvu.
• Yagbɔgbɔ sesẽ.
• Akɔtave.
• Dzi ƒe tsotso kabakaba.
• Ʋuʋudedi.
• Ʋusɔgbɔdɔ.
• Dzitsitsi. Ðewohĩ àse le ɖokuiwò me be yetsi dzimaɖi le mɔ wɔnuku aɖe nu, abe do ŋgɔ na dodokpɔ ene.
• Dzi ƒe tsotso.
• Aɖuɖɔtoedɔ (Seizures) ƒe dzesiwo.
• Ʋuʋudedi.
• Aɖuɖɔtoe sesẽ alo aɖuɖɔ ƒe agbɔsɔsɔ ƒe tɔtrɔ.
• Alɔ̃dɔdɔ ƒe kuxi.

Ne wozãe abe atike si wodona ɖe lãme na ame ene la:

• Vevesese, lãmetutudɔ, alo seselelãme ƒe bu le asiwo alo afɔwo ŋu.
• Vevesese, abi, alo abi le afisi wodo atikea le.
• Tsɔ kpe ɖe eŋu la, nugbegblẽ le ame ŋu atɔ̃ gbãtɔ siwo míeyɔ le akpa si nye "Yagbɔgbɔ" me le etame (nulɔdɔ, gbɔgbɔ sesẽ, akɔtave, dzi ƒe tsotso kabakaba, ʋuʋudedi) hã ate ŋu adzɔ.

Nu vevitɔe nye be ne èkpɔ dzesi siawo dometɔ aɖe la, ele be nàyi ɖɔkta gbɔ enumake eye mègawɔ nyametsotso aɖeke le ɖokuiwò si o..

Lãmesẽkuxi kawoe ate ŋu ado mo ɖa ne epinephrine ƒe agbɔsɔsɔ dzi ɖe kpɔtɔ?

Ne epinephrine ƒe agbɔsɔsɔ si le míaƒe ŋutilã me ɖiɖi wu alesi wòle be wòanɔ la, ate ŋu ahe lãmesẽkuxi aɖewo hã vɛ. Le kpɔɖeŋu me:

• Dzimaɖitsitsi: Ðewohĩ àse le ɖokuiwò me be vɔvɔ̃ kple dziɖeleameƒo le susu aɖeke ta o.
• Blanuiléle: Blanuiléle ƒe seselelãme, ɖekematsɔleme ɖe naneke ŋu o.
• Taɖuame: Taɖuame ate ŋu adzɔ enuenu.
• Alɔ̃dɔdɔ ƒe kuxiwo: Ðewohĩ màte ŋu adɔ alɔ̃ le zã me o, alo wò alɔ̃dɔdɔ ate ŋu atɔtɔ.
• Suklidɔ si bɔbɔ ɖe ʋu me (Hypoglycemia): Esia hã ate ŋu anye nɔnɔme sesẽ aɖe.
• Tɔtrɔ siwo vaa ʋu ƒe sisi kple dzi ƒe tsotso me.

Ne dzesi siawo tɔgbe le ŋuwò la, anyo wu be nàyi ɖɔkta gbɔ eye nàdi aɖaŋuɖoɖo.

Lãmesẽkuxi kawoe ate ŋu ado mo ɖa ne epinephrine ƒe agbɔsɔsɔ dzi ɖe edzi?

Kuxiwo doa mo ɖa ne epinephrine ƒe agbɔsɔsɔ sɔ gbɔ akpa. Le nɔnɔme mawo me la, nusiwo gbɔna ate ŋu adzɔ:

• Ʋusɔgbɔdɔ: Ʋu ƒe sisi ate ŋu adzi ɖe edzi ŋutɔ.
• Dzi ƒe tsotso kabakaba alo esi mesɔ o: Dzi ƒe tsotso ƒe tsɔtsɔme ate ŋu azu esi mesɔ o.
• Fifia si gbɔ eme.
• Ŋutilã si fa miamiamia alo le ɣie.
• Taɖuame sesẽ.
• Dzitsitsi ƒe seselelãme, dzitsitsi.
• Epinephrine zazã fũu akpa: Esia nye afɔku gã aɖe. Ate ŋu ahe ʋusɔgbɔdɔ, ʋusɔgbɔdɔ , kple ku gɔ̃ hã vɛ.
• Pheochromocytoma: Esia nye dɔdzẽ si dona le adrenal gland me. Ate ŋu ana epinephrine nawɔ fũ akpa.

Manyo be woaŋe aɖaba aƒu dzesi siawo tɔgbe dzi o. Ele vevie be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Nukae nye nusiwo ɖi wo nɔewo kple vovototo siwo le Epinephrine kple Norepinephrine dome?

Togbɔ be epinephrine nye ahɔhɔ̃mekawo ƒe dɔwɔwɔ kple lãmetsiŋusẽ siaa hã la, lãmetsiŋusẽ koŋue wòwɔa dɔ . Epinephrine, alo adrenaline, wɔa akpa vevi aɖe ŋutɔ le `avuwɔwɔ alo sisi ƒe ŋuɖoɖo` si ŋu míeƒo nu tsoe va yi me. Wozãnɛ hã abe atike ene tsɔ daa dɔléle geɖe siwo ate ŋu ade ame ƒe agbe afɔku me. Norepinephrine hã nye atike vevi aɖe, gake vovototo sue aɖe le alesi wo ame evea wɔa dɔe me.

Nu vevitɔ kekeake siwo dzi wòle be míaɖo ŋkui tso ŋutinya sia me (Take-Home Message) .

Enyo, eyata egbea míeƒo nu geɖe tso epinephrine, alo adrenaline ŋu. Nu ʋɛ aɖewo siwo dzi wòle be woaɖo ŋkui kpuie lae nye esi:

• Epinephrine (adrenaline) nye nusi le míaƒe ŋutilã me le dzɔdzɔme nu si kpena ɖe mía ŋu míekpɔa mía ta le nɔnɔme kpatawo me. Enye lãmetsiŋusẽ kple ahɔhɔ̃mekawo ƒe dɔwɔwɔ siaa.
• MíaƒeEsia le vevie na `avuwɔwɔ-alo-sitsoƒe` ƒe ŋuɖoɖo. Eya koŋ tae míaƒe ŋutilã trɔna ne míele vɔvɔ̃m alo ne míetsi dzodzodzoe.
• Wozãa epinephrine hã abe atike ene , vevietɔ le nɔnɔme siwo ate ŋu ade ame ƒe agbe afɔku me abe dzidɔ kple nulɔdɔ sesẽwo (anaphylaxis) ene me.
• Eɖanye agbɔsɔsɔa le sue alo lolo o, ate ŋu ahe lãmesẽkuxi vovovowo vɛ. Eyata ele vevie ŋutɔ be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo ne dzesi siwo mebɔ o le ŋuwò.

Eyata epinephrine nye atike wɔnuku aɖe si le vevie le míaƒe ŋutilã me. Mele mɔ kpɔm be mia kple wò lɔlɔ̃tɔwo miaɖe vi na mi ne mienyae!

` epinephrine, adrenaline, lãmetsiŋusẽ, ahɔhɔ̃mekawo ƒe dɔwɔwɔ, avuwɔwɔ alo sisi, nuteɖeamedzi, adrenal gland