Ðe folate ƒe agbɔsɔsɔ si medea dziwò oa? Mina míasrɔ̃ nu geɖe tso folate ƒe anyimanɔmanɔ ŋu!

Ðe ɖeɖi tea ŋuwò eye ɖeɖi tea ŋuwò hã ɣesiaɣia? Ðe nèsena le ɖokuiwò me ɣeaɖewoɣi be yeƒe mo biã eye yeƒe ta ʋuʋuna? Togbɔ be nusiawo nye nusiwo ŋu míate ŋu alé ŋku ɖo boo o hã la, ɣeaɖewoɣi la, nunyiame vevi aɖe ƒe anyimanɔmanɔ ate ŋu anɔ esia megbe. Emae nye nusi folate ƒe anyimanɔmanɔ nye. Mina míaƒo nu tso esia ŋu tsitotsito egbea, abe ɖe míele nu ƒom na mía xɔlɔ̃ aɖe ene.

Nukae nye folate? Ðe wòsɔ kple folic acid?

Kpuie ko la, folate nye nunyiame si le vitamin B9 ƒe ƒuƒoƒoa me eye wòle vevie na míaƒe ŋutilã. Ne míagblɔe tututu la, ele nuɖuɖu siwo míeɖuna dometɔ geɖe me le dzɔdzɔme nu. Bu eŋu kpɔ, amagbe dama dzẽwo abe aŋanyi, kale, kple collard greens, citrus atikutsetsewo abe amititsetse kple tangerines, nukuwo abe cashews kple peanuts, beans, peas, lentils, ƒumelãwo, azi, nyinotsinuwo, lã, tɔmelã, koklolã, kple nuku vovovowo... Folate le esiawo katã me.

Eyata nukatae folate le vevie na míaƒe ŋutilã alea gbegbe ɖo? Folate hiã vevie be míawɔ ʋumenugbagbevi dzĩ yeyewo le míaƒe ŋutilã me eye míawɔ domenyiŋusẽfianu si le míaƒe lãmenugbagbeviwo me, si nye DNA. Womate ŋu agblɔ folate ƒe vevienyenye wòagbɔ eme o, vevietɔ le fufɔɣi. Folate kpena ɖe vidzĩa ƒe tsitsi le vidzidɔ me ŋu ŋutɔ, vevietɔ le ahɔhɔ̃ kple aklã ƒe tsitsi me. Ekpena ɖe ame ŋu hã le mɔxexe ɖe vidzidzi ƒe gbɔdzɔgbɔdzɔwo nu.

Fifia èbia be, nukae nye folic acid? Folic acid nye folate ƒomevi aɖe si wowɔ. Esesẽna na míaƒe ŋutilã be wòadzra dzɔdzɔme folate gbogbo aɖewo ɖo. Gake ŋutilãa xɔa folic acid bɔbɔe. Esia tae folic acid doa ŋusẽ nuɖuɖu aɖewo siwo míeɖuna, abe bli, abolo, pasta, kple ŋdi me nuku aɖewo ene. Woate ŋu ano folic acid hã abe nuɖuɖu kpeɖeŋutɔ ene.

Kuxi kawoe ate ŋu ado mo ɖa le folate ƒe anyimanɔmanɔ ta?

Ne folate mesu mía si o la, kuxi ƒomevi ɖesiaɖe, si nye kuxiwo, ate ŋu ado mo ɖa.

Ke ne folate mesɔ gbɔ le fufɔɣi o ɖe?

Folate ƒe anyimanɔmanɔ le fufɔɣi nye kuxi sesẽ aɖe. Bu eŋu kpɔ ko be folate hiã vevie hafi vi si le dɔ me ƒe ahɔhɔ̃ kple aklã ƒe tsitsi nyuie. Ne mèkpɔe wòsu o la, àte ŋu axɔ vidzidzi ƒe gbɔdzɔgbɔdzɔ sesẽ siwo woyɔna be ahɔhɔ̃mekawo ƒe dɔmawɔmawɔ nyuie . Anɔ eme be èse nɔnɔmewo abe spina bifida kple anencephaly ene ŋu nya kpɔ . Emawo nye esia ƒe kpɔɖeŋuwo.

Menye ema ɖeɖeko o, ke folate ƒe anyimanɔmanɔ ate ŋu ana vidzidɔa ƒe gbagbã ƒe afɔkua nadzi ɖe edzi . Eyae nye be vidzidɔa, si naa nunyiame vidzĩa, ɖea eɖokui ɖa tso vidzidɔa gbɔ. Gakpe ɖe eŋu la, woate ŋu adzi vidzĩa kaba (preterm birth) , aloAte ŋu adzɔ be vidzidzi ƒe kpekpeme naɖiɖi . Numekuku aɖewo ɖee fia be folate ƒe anyimanɔmanɔ le fufɔɣi ate ŋu ahe nɔnɔmewo abe autism ene vɛ na ɖevia le eƒe tsitsime.

Nukae Nye Folate Deficiency Ʋusɔgbɔdɔ?

Nɔnɔme vevi bubu si ate ŋu atso folate ƒe anyimanɔmanɔ gbɔe nye ʋusɔgbɔdɔ si me folate mele o. Kpuie ko la, ʋusɔgbɔdɔ nye ne ʋumenugbagbevi dzĩ siwo le lãmesẽ me mesɔ gbɔ ɖe míaƒe ŋutilã me o. Ʋumenugbagbevi dzĩ siawo hiã vevie be woatsɔ oxygen ayi míaƒe ŋutilã ƒe lãkusiwo me. Ne folate mesɔ gbɔ na mí o la, ʋumenugbagbevi dzĩ siwo dona le ŋutilãa me ate ŋu alolo le mɔ si mesɔ o nu eye womegawɔa dɔ nyuie o. Esiae nye nusi míeyɔna be ʋusɔgbɔdɔ si me folate mele o.

Kuxi bubu siwo ate ŋu ado mo ɖa

Tsɔ kpe ɖe esia ŋu la, folate ƒe anyimanɔmanɔ ate ŋu ahe lãmesẽkuxi bubuwo vɛ. Esiawo dometɔ aɖewoe nye:

• Vidzidzimakpɔmakpɔ.
• Kansa ƒomevi aɖewo.
• Dzitodzito me dɔléle.
• Teteɖeanyi.
• Tagbɔdɔléle.
• Sidzedze ƒe dɔwɔwɔ dzi ɖe kpɔtɔ.
• Alzheimer ƒe dɔlélea.

Nukawoe nye folate ƒe anyimanɔmanɔ ƒe dzesiwo?

Folate ƒe anyimanɔmanɔ ƒe dzesi gbãtɔe nye ɖeɖiteameŋu. Tsɔ kpe ɖe eŋu la, dzesi bubuwo ate ŋu ado mo ɖa.

Dzesi siwo do ƒome kple ʋusɔgbɔdɔ

• Edze abe ɖe wòle ɣie ene .
• Yagbɔgbɔ sesẽ (gbɔgbɔtsixetsixe).
• Dzikudodo, dzikudodo kabakaba.
• Taɖuame.

Dzesiwo le nu me

• Aɖea biã eye wòsena le eɖokui me abe ɖe wòle veve sem ene.
• Nu me abi alo nu me abi.
• Nuɖuɖu ƒe vivisese dzi ɖeɖe kpɔtɔ.

Nɔnɔme siwo do ƒome kple lãmekawo ƒe dɔwɔwɔ

• Nuŋlɔɖi be, ŋkuɖoɖonudzi ƒe dɔmawɔmawɔ nyuie.
• Esesẽna be wò susu nanɔ nane ŋu.
• Sese le eɖokui me be yetɔtɔ.
• Gbɔdzɔgbɔdzɔ siwo le nyui tiatia tso vɔ̃ dome kple nyametsotsowo wɔwɔ me.

Nu bubu siwo bɔ

• Sese le eɖokui me be agbe mele ye si o eye ŋusẽ mele ye ŋu o.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.
• Teteɖeanyi.
• Kpekpeme dzi ɖeɖe kpɔtɔ.
• Dɔmetɔtrɔ.

Ne dzesi siawo dometɔ ɖeka alo esi wu nenema yi edzi le fu ɖem na wò la, anyo wu be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Nukawoe hea folate ƒe anyimanɔmanɔ vɛ?

Nusi koŋ gbɔ folate ƒe veve le enye nuɖuɖu si da sɔ si me nunyiame le ɖuɖu.Esia fia be míeɖua nuɖuɖu siwo me folate le le dzɔdzɔme nu, alo nuɖuɖu siwo me wotsɔ folic acid kpe ɖe wo ŋu la sɔ gbɔ o. Susu bubuwo hã ate ŋu anɔ anyi:

• Nuɖuɖumeŋusẽ ƒe dɔlélewo: Ne dɔléle aɖe abe Crohn ƒe dɔléle alo Celiac dɔléle ene le ŋuwò la, ɖewohĩ wò nuɖuɖumeŋusẽ mate ŋu axɔ folic acid nyuie o.
• Ahanono fũu akpa: Ame aɖewo meléa ŋku ɖe woƒe nuɖuɖu ŋu ne wono aha fũ o. Emegbe ŋutilãa mekpɔa folate si wòhiã o.
• Amagbewo kple atikutsetsewo ɖaɖa fũ akpa: Mía dometɔ geɖe lɔ̃a amagbewo kple atikutsetse siwo woɖa vie alo esiwo wofli la ɖuɖu. Ke hã, nu ɖeka si dzi wòle be míaɖo ŋkui enye be ne woɖa nu wògbɔ eme, i.e. ne wotsɔ wo de dzoxɔxɔ gã me la, ate ŋu agblẽ dzɔdzɔme folate si le nuɖuɖua me la dome. Eyata anyo wu be woaɖa amagbewo kple atikutsetsewo vie alesi nàte ŋui, alo woaɖu wo ƒuƒuie, abe le sabala me ene.
• Hemolytic Anemia: Esia nye ʋumenugbagbeviɣidɔ si me ʋumenugbagbevi dzĩwo tsrɔ̃na kabakaba akpa, gake womate ŋu awɔ yeyewo kabakaba nenema o.
• Atike aɖewo: Atike aɖewo siwo wozãna na asrãdɔ kple atike siwo wozãna na dɔlélewo abe dɔgbo ƒe dɔléle ene ate ŋu ado kplamatse folate ƒe xɔxlɔ̃.
• Ayiku me Ʋuʋu: Atike sia si wozãna na amesiwo ƒe ayiku mewɔa dɔ nyuie o hã ate ŋu ana folate nagbɔdzɔ.

Aleke woawɔ anya folate ƒe agbɔsɔsɔ si mede ame dzi o?

Ne èyi ɖɔkta gbɔ la, abia wò atikewɔwɔ ŋutinya kple eƒe dzesiwo. Mɔ ɖeka kolia si dzi nàto anya kple kakaɖedzi ne folate ƒe agbɔsɔsɔ si mede ame dzi o ye nye ʋudodokpɔ. Ʋudodokpɔ sia dzidzea folate agbɔsɔsɔme si le wò ʋu me. Ne folate ƒe agbɔsɔsɔ si le asiwò mesɔ gbɔ o la, efia be folate mesɔ gbɔ ɖe ŋuwò o.

Aleke wokpɔa folate ƒe anyimanɔmanɔ gbɔe?

Wò ɖɔkta ate ŋu aŋlɔ folic acid kpeɖeŋutɔ , alo folic acid ƒe atikekui aɖe na wò be wòatsɔ ada wò folate ƒe anyimanɔmanɔ. Ame tsitsi le mama dedie nu hiã folic acid si ade microgram 400 (mcg) gbesiagbe. Ke hã, wò ɖɔkta agblɔ ga home si tututu nèhiã na wò.

Azɔ hã, wò ɖɔkta aɖo aɖaŋu na wò be nàɖu nuɖuɖu si da sɔ eye nunyiame le . Esia fia be woaɖu atikutsetse, amagbewo, kple nuɖuɖu siwo me folate le le dzɔdzɔme nu alo nuɖuɖu siwo me wotsɔ folic acid kpe ɖo la geɖe wu.

Aleke woawɔ axe mɔ ɖe folate ƒe anyimanɔmanɔ nu?

Mɔ nyuitɔ si dzi woato axe mɔ ɖe folate ƒe anyimanɔmanɔ nue nye be woaɖu nuɖuɖu si naa lãmesẽ si me nuɖuɖu siwo me folate alo folic acid le hã le. Nuɖuɖu siwo me folate le le dzɔdzɔme nu dometɔ aɖewoe nye:

• Mɔliwo abe peas, beans, kple lentils ene.
• Citrus-kutsetsewo abe amititsetse kple tangerine ene.
• Amagbe dama viviwo abe aŋanyi, gotu kola, kple chard ene.
• Aklã.
• Ƒumelãwo.
• Azi kple nyinotsi nuɖuɖuwo.
• Lã kple koklolã.

Nuɖuɖu siwo me wotsɔ folic acid sɔ gbɔ ɖo alo wodo ŋusẽe:

• Abolo.
• Wɔ.
• Pasta.
• Mᴐli.
• Nuku siwo wotsɔ ɖua ŋdinu.

Folate agbɔsɔsɔme si nèhiã gbesiagbe nɔ te ɖe ƒe si nèxɔ kple nu bubuwo dzi. Ame tsitsi akpa gãtɔ hiã folate microgram 400 (mcg) gbesiagbe. If you are pregnant , ele vevie be nàno folic acid kpeɖeŋutɔ be nàkpɔ egbɔ be folate sɔ gbɔ na ye xɔm gbesiagbe.

Ne èle atike aɖe si doa kplamatse folate ƒe xɔxlɔ̃ nom la, ƒo nu kple wò ɖɔkta tso folic acid kpeɖeŋutɔ nono ŋu.

Nukae dzɔna ne folate ƒe veve le ŋunye?

Ne èdzi wò folate ɖuɖu ɖe edzi la, folate ƒe anyimanɔmanɔ ƒe ŋusẽkpɔɖeamedziwo adze tɔtrɔ gɔme. Ele vevie be woaɖu nuɖuɖu siwo me folate le alo nuɖuɖu siwo me wotsɔ folic acid kpe ɖe eŋu la sɔ gbɔ. Tsɔ kpe ɖe eŋu la, no folic acid kpeɖeŋutɔ ne ehiã. Ne folate mesu asiwò o la, kuxiwo abe ʋusɔgbɔdɔ ene ate ŋu anɔ anyi.

Nukae Nye Ahɔhɔ̃ me Folate ƒe Agbɔmasɔmasɔ?

Ahɔhɔ̃ me folate ƒe anyimanɔmanɔ nye nɔnɔme si mebɔ o. Edzɔna ne folate mele fugboea ƒe ahɔhɔ̃ me o. Vidzĩ siwo wodzi kple ahɔhɔ̃meka siwo me folate mele o la tsina nyuie le vidzĩme. Emegbe ne woxɔ ƒe 2 lɔƒo la, woƒe susu kple dɔwɔwɔ ƒe ŋutetewo dzea ɖiɖi gɔme. Susu ƒe dɔmawɔmawɔ nyuie, nuƒoƒo ƒe kuxi, asrãdɔ, kple ʋuʋu ƒe ɖoɖowɔwɔ ɖe ɖoɖo nu ƒe sesẽ (ataxia) ate ŋu asẽ ŋutɔ. Domenyiŋusẽfianu ƒe tɔtrɔ aɖe gbɔe nɔnɔme sia tsona .

Vovototo kae le vitamin B12 ƒe anyimanɔmanɔ kple folate ƒe anyimanɔmanɔ dome?

Vitamin B12 kple folate siaa le vevie na wò ʋumenugbagbevi dzĩwo kple DNA wɔwɔ. Wo dometɔ ɖesiaɖe ƒe anyimanɔmanɔ ate ŋu ana ɖeɖi nate ame, gbɔdzɔgbɔdzɔ, kple ʋusɔgbɔdɔ. Gake to vovo na folate la, vitamin B12 mele numiemiewo ƒe nuɖuɖuwo me o. Lã, azi, kple nyinotsi me koŋue B12 le. Eyata amagbeɖulawo kple amagbeɖulawo le afɔku gã aɖe me be vitamin B12 ƒe anyimanɔmanɔ nadze wo dzi. Vitamin B12 ƒe anyimanɔmanɔ vevie ate ŋu ahe kuxiwo abe blanuiléle, susu ƒe tɔtɔ, ŋkuɖoɖonudzi ƒe dɔmawɔmawɔ nyuie, aɖuɖɔtoe ƒe dɔmawɔmawɔ nyuie, kple vivisese kple ʋeʋẽ ƒe bublu vɛ.

Nukae nye MTHFR ƒe nɔnɔme vovovowo?

Nukae nye MTHFR?Enzyme aɖe si woyɔna be methylenetetrahydrofolate reductase. Ame aɖewo ƒe domenyiŋusẽfianu ƒe tɔtrɔ , alo tɔtrɔ, le domenyiŋusẽfianu si woyɔna be MTHFR me. Ne tɔtrɔ sia le ŋuwò la, wò ŋutilã mate ŋu atrɔ folate wòazu eƒe nɔnɔme si wɔa dɔ, si nye 5-MTHF (5-methyltetrahydrofolate) . Dzɔdzɔmenugbagbevi sia gblẽa nu le Hispaniatɔwo ƒe 25% lɔƒo, yevuwo ƒe 10% lɔƒo, Asiatɔwo ƒe 10% lɔƒo, kple ameyibɔwo ƒe 1% lɔƒo ŋu. Ne tɔtrɔ sia le ŋuwò la, ate ŋu aɖe vi na wò ne èno folate kpeɖeŋutɔ si me 5-MTHF, si nye folic acid si wɔa dɔ le.

Mina míaɖo ŋku edzi kpuie (Take-Home Message) .

Enyo, eyata fifia ènya be folate nye vitamin vevi aɖe na míaƒe ŋutilã, vevietɔ na ʋumenugbagbevi dzĩwo kple DNA wɔwɔ, alo? Vevietɔ ne èfɔ fu la, folate hiã vevie na viwòa ƒe tsitsi. Folate ƒe anyimanɔmanɔ mebɔ o, gake ate ŋu ahe kuxi sesẽwo abe vidzidzi ƒe gbɔdzɔgbɔdzɔ kple ʋusɔgbɔdɔ ene vɛ.

Eyata ele vevie ŋutɔ be woaɖu nuɖuɖu si me atikutsetsewo, amagbewo (vevietɔ amagbe dama viviwo), kple nuɖuɖu bubu siwo me folate alo folic acid le. Ne ehiã la, àte ŋu ano folic acid kpeɖeŋutɔ hã le atikewɔlawo ƒe aɖaŋuɖoɖo nu. Anyo wu be nàƒo nu kple wò ɖɔkta tso folate agbɔsɔsɔme si nèhiã gbesiagbe ŋu. Mina míalé be na nu sue siawo be míanɔ lãmesẽ me!

` Folate, folic acid, vitamin B9, ʋusɔgbɔdɔ, fufɔfɔ, vidzidzi ƒe gbɔdzɔgbɔdzɔ, nunyiame, eƒe anyimanɔmanɔ