Ðe viwòa le tsitsim kabakaba akpaa? Mina míasrɔ̃ nu tso amegãxiwo ŋu!

Ɣeaɖewoɣi la, mía viwo tsina kabakaba ŋutɔ, alo? Gake mesɔ be wotsina zi ɖeka sã wu ɖevi bubuwo, eye woƒe abɔwo lolona o. Nusi gbɔ esia tso ate ŋu anye nɔnɔme si mebɔ kura o. Egbea míele nu ƒom tso nɔnɔme sia tɔgbe ŋu, si nye ‘Gigantism’.

Nukae nye ‘Amegãxinyenye’?

Kpuie ko la, gigantism nye nɔnɔme si mebɔ o si me ɖevi alo sɔhɛ wɔa tsitsimeŋusẽ (GH) fũ akpa . Esia tae ɖevi siawo tsina wu ame bubuwo sã. Zi geɖe la, lãkusi sue aɖe si lolo abe pea ene si le míaƒe ahɔhɔ̃a ƒe gɔme lae wɔa tsitsiŋusẽ sia (GH). Woyɔa esia be pituitary gland. Gake ne dɔdzẽ sue aɖe do le lãkusi sia me la, ate ŋu awɔ tsitsiŋusẽ (GH) geɖe wu esi hiã. Ɣemaɣie amegãxiwo dzɔna.

Pituitary Gland nye lãkusi sue aɖe si le ahɔhɔ̃a ƒe gɔme, le Hypothalamus te. Le nyateƒe me la, eɖea lãmetsiŋusẽ siwo ade 8 ɖe go. Tsitsi ƒe Lãmetsiŋusẽ (GH) nye wo dometɔ ɖeka.

Tsitsi ƒe Lãmetsiŋusẽ, si wogayɔna be Amegbetɔ ƒe Tsitsi ƒe Lãmetsiŋusẽ (hGH) le vevie na ɖeviwo ƒe tsitsi. Edzea ŋutilã ƒe akpa geɖe dzi eye wòkpena ɖe ɖevia ŋu wòtsina nyuie. Gake tsitsi ƒe ƒuƒoƒo aɖewo le míaƒe ƒuwo me siwo woyɔna be Epiphyses/Growth Plates, eye ne wonya tu keŋkeŋ (i.e. le sɔhɛmenɔɣi megbe) ko la, tsitsi ƒe lãmetsi (GH) medzia kɔkɔme ɖe edzi o. Nusi wòwɔnae nye be wòléa ƒuwo, ƒunukpeƒetetedɔ, kple ŋutinu bubuwo ƒe wɔwɔme kple woƒe lãmenugbagbeviwo ƒe dɔwɔwɔ me ɖe asi. Tsitsi ƒe lãmetsi sia (GH) do ƒome kplikplikpli kple lãmetsi aɖe si woyɔna be Insulin-like Growth Factor 1 (IGF1), si míaƒe aklã wɔna. Ne wotsɔ eve siawo ƒo ƒu kpena ɖe ame ŋu le tsitsi kple lãmenugbagbeviwo ƒe dɔwɔwɔ me.

Gigantism nye nɔnɔme si me ŋutilãa wɔa tsitsiŋusẽ (GH) fũ akpa, si wɔnɛ be lãmekawo, ƒuwo, kple kadodoŋusẽwo tsina kabakaba. Esia wɔnɛ be ame ƒe kɔkɔme mesɔna o eye wòtrɔna zi geɖe le ŋutilã ƒe lãkusi falɛfalɛwo me. Ne womewɔ atike na ame aɖewo siwo ŋu gigantism le o la, woate ŋu akɔ wu afɔ 8.

Eyata ele vevie ŋutɔ be woakpɔ dɔlélea eye woadze edada gɔme kaba ale si woate ŋui nenye be amegãxiwo le eŋu.

Vovototo kae le ‘Gigantism’ kple ‘Acromegaly’ dome?

Gigantism kple acromegaly siaa nye nɔnɔme siwo tso tsitsi ƒe lãmetsi si sɔ gbɔ (GH) gbɔ. Vovototoa le amesi tua eŋu ɖo me. Acromegaly dzɔna le ame tsitsiwo me. Gãnyenye doa mo ɖa le ɖeviwo kple sɔhɛ tsitsi siwo gakpɔtɔ le tsitsim, si fia be womeɖo woƒe ƒewuiwo me haɖe o la me.

Kpuie ko la, gigantism dzɔna ne tsitsi ƒe lãmetsi (GH) ƒe agbɔsɔsɔ dzi ɖe edzi hafi tsitsi ƒe agbalẽvi siwo le ɖeviwo ƒe ƒuwo me la tu (i.e., hafi sɔhɛmenɔɣi wu enu).

Ne wò tsitsi ƒe lãmetsi (GH) ƒe agbɔsɔsɔ dzi ɖe edzi le wò tsitsi ƒe agbawo tutu vɔ megbe la, ate ŋu ahe acromegaly vɛ. Màtsi o, gake GH si sɔ gbɔ ate ŋu akpɔ ŋusẽ ɖe wò ƒuwo ƒe nɔnɔme, wò ŋutinuwo ƒe lolome, kple lãmesẽkuxi bubuwo dzi.

Gigantism nye nɔnɔme si mebɔ kura o wu acromegaly.

Amekae xɔa gigantism? Aleke gbegbe wòbɔe?

Togbɔ be esia nye nɔnɔme si mebɔ kura o hã la, gãnyenye ate ŋu ado mo ɖa le ɖevi ɖesiaɖe si ƒe tsitsi ƒe agbawo metu haɖe o (i.e., womewu sɔhɛmenɔɣi nu o) ŋu. Ebɔ ɖe ŋutsuviwo me wu nyɔnuviwo.

Le nyateƒe me la , gãnyenye nye nɔnɔme si mebɔ kura o ŋutɔ. Le kpɔɖeŋu me, ame siwo ade 100 koe wokpɔ le United States vaseɖe fifia. Eyata àte ŋu akpɔ alesi gbegbe wòbɔe la le susu me.

Aleke ɖeviwo ƒe tsitsi si sɔ la dzɔnae? Vovototo kae le amegãxinyenye dome?

Tsitsi ƒe lãmetsi (GH) ye kpɔa ŋusẽ ɖe tsitsi dzi le ɖevime. Eyae nye be ekpɔa ŋusẽ ɖe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi esime wòle tsitsim si woate ŋu adzidze le ƒuwo, lãmekawo, kple lãkusiwo me. Zi geɖe la, tsitsi nyea nusi li ke nyuie vaseɖe esime ɖevi naɖo sɔhɛme.

Le sɔhɛmenɔɣi la, gbɔdɔdɔ ƒe lãmetsiwo (estrogen kple testosterone) ƒe dodo dzina ɖe edzi ŋutɔ. Esia nana be epiphyses (tsitsi ƒe agbalẽvi) siwo le ɖevi ƒe ƒu didiwo ƒe nuwuƒewo la tsia vivivi. Ne epiphyses la tu keŋkeŋ, si fia be ne sɔhɛmenɔɣi wu enu la, kɔkɔme ƒe tsitsi nu tsona.

Domenyiŋusẽfianu vovovo siwo dome wonyi tso wo dzilawo gbɔ, nuto si me wole, kple woƒe gbɔdɔdɔ ƒe ƒuƒoƒoe kpɔa alesi ɖevi tsina kabakabae kple alesi woƒe kɔkɔme mamlɛtɔ anye ne eɖo sɔhɛmenɔɣi.

Le gigantism gome la, ɖevia tsina kabakaba ŋutɔ, eye wòkɔna wu ɖevi bubu siwo xɔ ƒe kple vidzinu ɖeka tɔgbe sã. Gake gigantism ƒe dzesiwo ate ŋu adze abe ɖevimenɔɣi ƒe tsitsi ƒe ʋuʋu si sɔ ene le gɔmedzedzea me, si ana wòasesẽ na dzilawo be woade dzesii.

Ne nyabiase alo ɖikeke aɖe le viwòa ƒe tsitsi ŋu la, kpɔ egbɔ be yeƒo nu kple eƒe ɖɔkta.

Nukawoe nye gigantism ƒe dzesiwo?

Tsitsi ƒe lãmetsi (GH) si sɔ gbɔ wu gbɔe wòtsona be amegãxiwo dzɔna. Azɔ hã, dɔdzẽ si le lãkusi me ate ŋu aƒoe ɖe ahɔhɔ̃ kple lãmeka siwo te ɖe eŋu ŋu, si ahe dzesi aɖewo vɛ. Gãnyenye ƒe dzesi vevitɔe nye tsitsi si gbɔ eme.Ðevi siwo ƒe lolome nye gigantism la tsina kabakaba ŋutɔ le woƒe kɔkɔme me.

Tsɔ kpe ɖe ame ƒe kɔkɔme/lolo ŋutɔ ƒe ƒexɔxɔ ŋu la, ŋutilã ƒe nɔnɔme siwo wokpɔna le gigantism me dometɔ aɖewoe nye:

• Ŋgonu si dzena ŋutɔ kple aɖuɖɔtoe si dzena nyuie.
• Dometsotsowo ƒe amesinɔnɔ le aɖuwo dome.
• Mo ƒe dzedzeme ƒe ƒoƒo.
• Asi kple afɔ gãwo, kple asibidɛ siwo le ɣie.

Dzesi bubu siwo woate ŋu akpɔ dometɔ aɖewoe nye:

• Ememe ŋutinuwo, vevietɔ ɖevia ƒe dzi ƒe lolome.
• Fifia fũu akpa (hyperhidrosis).
• Nukpɔkpɔ eve alo nukpɔkpɔ sesẽ le gota gome.
• Taɖuame.
• Ƒunukpeƒewo ƒe vevesese.
• Ƒewuiwo ƒe heheɖemegbe.
• Dzinukpɔkpɔ si mebɔ o.
• Le kpɔɖeŋu me, alɔ̃dɔdɔ ƒe kuxiwo, alɔ̃dɔdɔ ƒe gbɔgbɔtsixetsixe.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.

Ne dzesi siawo le viwòa ŋu la, ele vevie ŋutɔ be nàƒo nu kple ɖɔkta kaba ale si nàte ŋui.

Nukawoe hea amegãxiwo vɛ?

Zi geɖe la, dɔdzẽ si me dɔlékui aɖeke mele o (pituitary adenoma) si le ɖevia ƒe lãkusi me gbɔe gigantism tsona. Esia nana be tsitsi ƒe lãmetsi (GH) dona fũ akpa. Ne wokpɔ ɖevi siwo ŋu gigantism le la, ɣesiaɣi kloe la, pituitary adenoma gã aɖe (dɔdzẽ si ƒe didime nye milimeta 10 alo esi lolo wu), si woyɔna be macroadenoma, nɔa wo ŋu. Ate ŋu atso ʋuka si me ʋu sina tona ƒe lolome si woyɔna be pituitary hyperplasia hã gbɔ.

Domenyiŋusẽ ƒe tɔtrɔ aɖe le ɖevi geɖe siwo ŋu gigantism le ŋu si nana pituitary tumor. Domenyiŋusẽfianu ƒe tɔtrɔ si bɔ wu si do ƒome kple gigantism enye tɔtrɔ alo eƒe ɖeɖeɖa le AIP domenyiŋusẽfianu me. Esia gblẽa nu le amesiwo ŋu gigantism le ƒe 29% lɔƒo ŋu.

Gigantism ate ŋu adzɔ hã abe domenyiŋusẽfianu ƒe dɔléle gbogbo aɖewo siwo mebɔ kura o siwo dzia afɔku si le pituitary tumor si ɖea tsitsi ƒe lãmetsi (GH) dona me la ƒe akpa aɖe ene. Dɔléle siawo dometɔ aɖewoe nye:

• Carney complex: Esia nye domenyiŋusẽfianu ƒe dɔléle si gblẽa nu le ŋutigbalẽ ƒe amadede ŋu eye wònana ŋutigbalẽ, dzi, kple lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe dɔdzẽ siwo me dɔlékui aɖeke mele o dona. Ame siwo ŋu Carney complex le la dometɔ siwo ade 10% va ɖo 13% xɔa tsitsime lãmetsi (GH)-secreting pituitary adenomas, siwo zi geɖe tsina blewu.
• McCune-Albright ƒe dɔlélea:Esia nye domenyiŋusẽfianu ƒe nɔnɔme si gblẽa nu le ƒuwo, ŋutigbalẽ, kple lãmenugbagbeviwo ƒe dɔwɔwɔ ŋu. Enaa café-au-lait ƒe teƒeteƒewo nɔa ŋutigbalẽa ŋu, abi le ƒuwo me, eye wònaa ƒewuiwo tsia kaba. Ame siwo ŋu McCune-Albright ƒe dɔlélea le ƒe 20% va ɖo 30% ƒe tsitsi ƒe lãmetsi si sɔ gbɔ (GH) le wo si. Zi geɖe la, lãkusi si lolo (hyperplasia) alo lãkusi ƒe adenoma gbɔe esia tsona.
• Multiple Endocrine Neoplasias (MEN) ƒomevi 1 alo 4: Esiawo nye domenyiŋusẽfianu ƒe nɔnɔmewo. Le go sia me la, wò lãmenugbagbeviwo dometɔ ɖeka alo esi wu nenema va wɔa dɔ akpa, alo dɔdzẽ aɖe dona. Esia ate ŋu alɔ ƒunukpeƒetetedɔ si ɖea tsitsiŋusẽ (GH) dona ɖe eme.
• Neurofibromatosis: Esia nye domenyiŋusẽfianu ƒe dɔléle si woyɔna be neurocutaneous disorders. Esiawo gblẽa nu le ŋutigbalẽ kple lãmekawo ŋu. Lãmenugbagbeviwo ƒe tsitsi ƒe dzidziɖedzi si mesɔ o gbɔe nɔnɔme siawo tsona. Esia ate ŋu ana dɔdzẽwo nadzɔ le ŋutilã bliboa me. Esiawo ate ŋu anye dɔdzẽ si ɖea tsitsi ƒe lãmetsi (GH) doa goe.
• Ƒome ƒe Pituitary Adenomas (FIPA): Esia nye domenyiŋusẽfianu ƒe dɔléle. Elɔ pituitary adenomas ƒe dzɔdzɔ ɖe eme. Esiawo ate ŋu anye adenomas siwo ɖea tsitsi ƒe lãmetsi (GH) ɖe go.

Aleke wokpɔa amegãxiwoe?

Gigantism ateŋu asesẽ vie be woakpɔe elabena enye nɔnɔme si mebɔ kura o, eye le esi ɖeviwo ƒe tsitsi ateŋu ato vovo ŋutɔ le domenyiŋusẽfianu kple nutome ta.

Zi geɖe la, ɖɔktawo susuna be enye gãnyenye ne ɖevi ƒe kɔkɔme wu eƒe kɔkɔme si woɖo ɖi zi etɔ̃ le woƒe gbɔdɔdɔ kple ƒe si woxɔ nu, alo to vovo zi gbɔ zi eve wu kɔkɔme si wobu tso ɖevia dzilawo ƒe kɔkɔme le mama dedie nu.

Ne viwò ƒe ɖɔkta susui be viwòa ƒe lãme sẽ la, anɔ eme be aɖo wò ɖe lãmenugbagbeviwo ƒe dɔwɔwɔ ŋuti nunyala (ɖɔkta si bi ɖe dɔléle siwo do ƒome kple lãmetsiŋusẽ me) gbɔ. Ðɔktaa anɔ te ɖe viwòa ƒe atikewɔwɔ ŋutinya, ƒomea ƒe atikewɔwɔ ŋutinya, ŋutilã dodokpɔ tsitotsito, kple dodokpɔ tɔxɛwo abe ʋudodokpɔ kple nɔnɔmetatawo dodokpɔ ene dzi akpɔ dɔlélea.

Dodokpɔ kawoe wozãna tsɔ dea dzesi dɔléle si nye gigantism?

Ne viwòa ƒe ɖɔkta susui be ʋu gã aɖe le eŋu la, woate ŋu awɔ dodokpɔ siwo gbɔna atsɔ aɖo kpe dɔlélea dzi:

• Tsitsi ƒe Lãmetsiŋusẽ kple IGF-1 (Insulin-like Growth Factor 1) ƒe ʋudodokpɔ: Dodokpɔ siawo dzidzea lãmetsi vovovowo ƒe agbɔsɔsɔ le ʋu si woɖe tso ɖevia ƒe ʋuka me me. Ne agbɔsɔsɔa sɔ gbɔ wu alesi wòle dzɔdzɔmee la, ate ŋu anye gãnyenye ƒe dzesi.
• Glucose Tolerance Test: Dodokpɔ sia dzidzea alesi ɖevi ƒe tsitsime lãmetsiŋusẽ wɔa nu ɖe ​​sukli ŋui. Le dodokpɔ sia ta la, ɖɔkta ɖea ʋu le ʋuka aɖe me le ɣeyiɣi vovovowo me ne ɖevia no sukli (sukli) tsi aɖe vɔ.
• Nɔnɔmetatawo dodokpɔ: Ne ʋudodokpɔwo ɖo kpe edzi be viwòa ƒe lolome le gã la, zi geɖe la, wò ɖɔkta aɖo aɖaŋu be woawɔ MRI (Magnetic Resonance Imaging) scan alo CT (Computed Tomography) scan. Amesiawo te ŋu kpɔa alesi pituitary tumor la ƒe lolome kple afisi wòle nyuie. Woate ŋu akpe ɖe ame ŋu hã be woanya atikewɔwɔ si tututu hiã.

Ne wokpɔe be lã gã aɖe le viwòa ŋu la, ɖɔkta ate ŋu awɔ dodokpɔ bubu aɖewo atsɔ akpɔe ɖa be dɔlélea gblẽ nu le ŋutilã ƒe akpa bubuwo hã. Dodokpɔ siawo ate ŋu anye:

• Echocardiogram si woatsɔ akpɔe ɖa be dzitodzito me kuxiwo le eŋu hã.
• Alɔ̃dɔdɔ ŋuti nusɔsrɔ̃ dodokpɔwo be woakpɔe ɖa be alɔ̃dɔdɔ ƒe gbɔgbɔtsixe tsia ƒowò hã.
• X-ray alo DEXA/DXA scan wɔwɔ be woatsɔ akpɔ wò ƒuwo ƒe lãmesẽ.

Aleke wowɔa nu ɖe ​​amegãxiwo ŋui?

Taɖodzinu vevi siwo le gigantism dada ŋue nye:

• ‘Tsitsi ƒe lãmetsi’ (GH) kple ‘insulin-like growth factor 1’ (IGF1) ƒe agbɔsɔsɔ dzi ɖuɖu dedie.
• ‘Pituitary tumor’ ƒe tsitsi dzi kpɔkpɔ.
• Ŋusẽ si dɔdzẽ si le lãkusi me kpɔna ɖe ahɔhɔ̃meka siwo te ɖe eŋu kple ŋku ƒe lãkusi dzi dzi ɖeɖe kpɔtɔ.
• Tsitsi ƒe lãmetsi (GH) ƒe ŋusẽkpɔɖeamedzi ɖe ŋutilã ƒe dɔwɔwɔ bubuwo dzi dada alo edzi ɖeɖe kpɔtɔ.

Zi geɖe la, ɖɔktawo zãa atike vovovowo tsɔ daa gigantism , eye amekoko kple keklẽŋusẽdɔdamɔnue nye atike vevitɔwo.

Togbɔ be atike nyuiwo li siwo woatsɔ ada tsitsimeŋusẽ (GH) si sɔ gbɔ ɖe ame tsitsiwo me (acromegaly) hã la, womesrɔ̃ nu tso ŋusẽ si atike siawo kpɔna ɖe ɖeviwo dzi ŋu nyuie haɖe o.

Amekoko na Gigantism

Amekokoe nye atike si wozãna wu na gigantism. Taɖodzinuae nye be woaɖe ƒunukpeƒetetedɔa ɖa alo woaɖe eƒe lolome dzi akpɔtɔ. Esi wònye be zi geɖe la, dɔdzẽ si nana ɖevia lolona ta la, ahiã be woawɔ dɔ na ɖevia zi geɖe be wòakpɔ tsitsimeŋusẽ (GH) ƒe agbɔsɔsɔ dzi nyuie.

Viwòa ƒe amekola ate ŋu azã amekokomɔnu aɖe si woyɔna be transsphenoidal surgery atsɔ aɖe pituitary tumor aɖe ɖa. Esia bia be nàwɔ dɔa to viwòa ƒe ŋɔti me kple to sphenoid sinus (si nye do aɖe si le tagbɔ me le ŋɔti megbe, le ahɔhɔ̃a te) me.

Kekeli ƒe Atikewɔwɔ na Gigantism

Ne amekoko mete ŋu ɖe tsitsimeŋusẽ ƒe agbɔsɔsɔ dzi kpɔtɔ o la, keklẽŋusẽdɔdamɔnu ate ŋu akpe ɖe ame ŋu. Esia bia be woazã dɔwɔnu tɔxɛwo atsɔ aɖo keklẽŋusẽ ƒe keklẽwo ɖe dɔdzẽa ŋu. Atikewɔwɔ sia wɔa dɔ vivivi. Ate ŋu abia be woawɔ atike nɛ zi geɖe, eye woagbɔ ɖe eme ɣeyiɣi didi le wo dome. Ate ŋu axɔ ƒe geɖe hã hafi woakpɔ emetsonu bliboa.

Nukawoe nye kuxi siwo dona tso atikewɔwɔ me?

Le amekoko kple/alo keklẽŋusẽ ƒe atikewɔwɔ ta la, amesiwo ŋu gigantism le la dometɔ siwo ade 60% va xɔa nɔnɔme aɖe si woyɔna be hypopituitarism le atikewɔwɔ vɔ megbe. Esia nye ne lãmetsiŋusẽ siwo pituitary gland wɔna la dometɔ ɖeka, geɖe, alo wo katã mewɔa dɔ nyuie o. Wotsɔa atike siwo wotsɔ ɖɔlia lãmetsiŋusẽwoe daa dɔ na ʋumenugbagbeviɣidɔ.

Kuxi siwo ate ŋu ado mo ɖa le amekoko be woaɖe ƒunukpeƒetetedɔ aɖe ɖa me dometɔ aɖewoe nye:

• Ʋu si le dodom.
• Ahɔhɔ̃mekawo me Tsi (CSF) ƒe sisi.
• Meningitis (ahɔhɔ̃ me dɔléle).
• Sodium (dze) kple tsi ƒe dadasɔ le ŋutilãa me ƒe bu.

Kekelidɔdada ƒe nugbegblẽ ate ŋu anye:

• Vidzidzi ƒe Dɔmawɔmawɔ nyuie.
• Nukpɔkpɔ ƒe bu kple ahɔhɔ̃ ƒe gbegblẽ (mebɔ o).
• Tumor ƒe wɔwɔ ƒe geɖe le atikewɔwɔ vɔ megbe (mebɔ o).

Ðe woate ŋu axe mɔ ɖe gãnyenye nua? Nukae nye nyagblɔɖia?

Nublanuitɔe la, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe gãnyenye nu o. Gake ekpɔkpɔ kaba le vevie ŋutɔ. Atikewɔwɔ kaba ate ŋu akpe ɖe ŋuwò nàxe mɔ ɖe tɔtrɔ siwo nana viwòa kɔkɔ akpa la nu alo atrɔ wo.

Nusiwo wogblɔ ɖi na ɖeviwo kple sɔhɛ tsitsi siwo ŋu wokpɔ be dɔléle gã aɖe le la nɔ te ɖe nu geɖe dzi:

• Alesi wokpɔ dɔlélea kaba alo tsi megbee.
• Aleke gbegbee atikewɔwɔwo wɔa dɔe le tsitsime lãmetsiŋusẽ ƒe agbɔsɔsɔ dzi kpɔkpɔ me?
• Ne kuxi aɖewo li siwo do ƒome kple gigantism.

Zi geɖe la, kuxi geɖe nɔa ame tsitsi siwo ŋu wokpɔ dɔlélea le ŋu wu amesiwo wokpɔ le woƒe ɖevime. Anɔ eme be esia tso tsitsi ƒe lãmetsi kple tsitsi ƒe akpa 1 si le abe insulin ene (IGF1) zazã ɣeyiɣi didi gbɔ.

Eyata ne ède dzesi tɔtrɔ siwo mebɔ o, siwo mèle mɔ kpɔm na o le viwòa ƒe tsitsi kple/alo eƒe ŋutilã ƒe nɔnɔmewo me la, ele vevie be nàƒo nu kple woƒe ɖɔkta kaba ale si nàte ŋui.

Nukae nye agbenɔƒe si ame si ƒe ŋutilã lolo le? Nukawoe nye kuxi siwo dona tso eme ɣeyiɣi didi?

Ele vevie be woakpɔ gigantism kaba ahadae be woaxe mɔ ɖe kɔkɔme si gbɔ eme kple kuxi siwo do ƒome kplii nu eye woana agbenɔƒe nadzi ɖe edzi.

Ne womewɔ atike na amegãxi o la, edoa ƒome kple kuxi gãwo eye ame ƒe ku ate ŋu ade esi sɔ gbɔ zi gbɔ zi eve.

Kuxi siwo nɔa anyi didi siwo ame aɖewo siwo ŋu gigantism le doa goe le woƒe kɔkɔme si gbɔ eme kple ŋusẽ si wòkpɔna ɖe ame ƒe tsitsime lãmetsi si sɔ gbɔ akpa dzi le wo katã ta dometɔ aɖewoe nye:

• Ʋuʋu sesẽ (Mobility) le lãmekawo ƒe gbɔdzɔgbɔdzɔ ta.
• Ƒumeŋuɖui (ƒunukpeƒetetedɔ).
• Peripheral Neuropathy (lãmeka siwo le lãme na ame ƒe dɔlélewo).
• 'Alɔ̃dɔdɔ ƒe Gbɔgbɔtsixetsixe'.
• Dzi ƒe lolome (cardiomegaly) kple dzitodzito me ʋukawo ƒe kuxiwo.
• Lãmetsiŋusẽ ƒe kuxiwo abe Suklidɔ Ƒomevi 2 ene.

Gakpe ɖe eŋu la, woate ŋu aɖe amesiwo ŋu gigantism si womeda atike na o le ƒe agbenɔnɔ dzi akpɔtɔ le kuxi siwo le gbesiagbedɔwo abe awuƒle kple mɔzɔzɔ ene me le esi woƒe kɔkɔme sɔ gbɔ akpa ta.

Ɣekaɣie wòle be nàkpɔ viwò ƒe ɖɔkta le gigantism ŋu?

Ne wokpɔe be viwòa ƒe lãme gblẽ la, ahiã be wòayi woƒe ɖɔkta kple/alo lãmenugbagbeviwo ƒe dɔwɔwɔ ŋuti nunyala gbɔ edziedzi be wòalé ŋku ɖe atikewɔwɔa ƒe ŋgɔyiyi ŋu eye wòakpɔ egbɔ be woƒe lãmetsiŋusẽ ƒe agbɔsɔsɔ le ɖoɖo nu.

Ne ède dzesi tɔtrɔ aɖewo le viwòa ƒe tsitsi kple/alo eƒe ŋutilã ƒe nɔnɔmewo ŋu la, ele vevie be nàƒo nu kple viwòa ƒe ɖɔkta kaba ale si nàte ŋui. Togbɔ be anɔ eme be amegãxiwo gbɔe wòtso o hã la, enyo be woaku tɔtrɔ ɖesiaɖe si ŋu ɖikeke le me. Enyo wu be woade dzesi amegãxiwo kaba, eye zi geɖe la, amesiwo ŋu amegãxiwo le nɔa agbe le lãmesẽ me. Ne nya aɖe le asiwò ku ɖe viwòa ƒe tsitsi ŋu la, mègavɔ̃ be yeabia wò ɖɔkta o. Wole afima be yewoakpe ɖe ŋuwò.

Nu vevitɔ kekeake siwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Gigantism nye nɔnɔme si mebɔ o gake ate ŋu anye nu sesẽ. Nu vevitɔe nye be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo enumake ne ède dzesi nane si mebɔ o alo ɖikeke le viwòa ƒe tsitsi ŋu, abe eƒe tsitsi kabakaba wu alesi nèkpɔ mɔe alo eƒe abɔ kple afɔwo lolo ene.

Ðo ŋku edzi be ne èkpɔ dɔlélea kaba eye nèdae la, edzia mɔnukpɔkpɔ si li be viwòa nanɔ agbe si le lãmesẽ me, si sɔ la ɖe edzi ŋutɔ. Mègatsi dzi o, ɖɔktawo li be yewoakpe ɖe mia kple viwòa ŋu. Ƒo nu tso nu ɖe ​​sia ɖe si ŋu nètsi dzi ɖo ŋu na wo.

` Gigantism, Tsitsi ƒe Lãmetsiŋusẽ, Pituitary Gland, Tsitsi le Ðeviwo me, Kɔkɔme Dzidziɖedzi, Acromegaly