Mina míasrɔ̃ nu tso ʋumenugbagbeviɣidɔ ŋu pɛpɛpɛ. Nuka tututue wònye, eye ɖe wònye nusi wòle be woavɔ̃ na?

Ðewohĩ èvɔ̃ vie esi nèse nya " ʋumenugbagbeviɣidɔ ." Ema sɔ, elabena zi geɖe la, míevɔ̃na ne míese nya siawo tɔgbe. Gake ne ènya nusi tututu wònye, nusita wòdzɔna, dzesi siwo le eŋu, kple ne atike aɖe li hã la, vɔvɔ̃ ma dzi ɖena kpɔtɔna ŋutɔ. Eyata egbea, míele nu ƒom tso ʋumenugbagbeviɣidɔ sia si woyɔna be ʋumenugbagbeviɣidɔ ŋu le mɔ bɔbɔe aɖe ŋutɔ si gɔme nàte ŋu ase nu. Abe alesi xɔ̃wò alo ƒometɔ aɖe agblɔe na wò ene.

Nukae nye Ʋumenugbagbeviɣidɔ?

Kpuie ko la, ʋumenugbagbeviɣidɔ nye kansa si dzea egɔme tso ʋu me . Ƒumeŋuɖui ye nye teƒe vevitɔ si wowɔa ʋu le le míaƒe ŋutilã me. Ele abe dɔwɔƒe ene. Le ƒumeŋuɖui sia me la, ʋumenugbagbeviwo, vevietɔ ʋumenugbagbevi ɣi siwo metsi o , dzea tsitsi gɔme kabakaba le mɔ si mesɔ o nu. Nya "ʋumenugbagbeviɣidɔ" tso Helagbe me nya "leukos" (yevu) kple "haima" (ʋu) me.

To vovo na kansa ƒomevi bubuwo la , zi geɖe la , ʋumenugbagbeviɣidɔ mexɔa dɔdzẽ si woate ŋu akpɔ le X-ray alo CT scan me o .

Ʋumenugbagbeviɣidɔ ƒomevi vovovowo li. Wo dometɔ aɖewo bɔ ɖe ɖevi suewo me wu, gake bubuwo ya bɔ ɖe ame tsitsiwo me wu. Atikewɔwɔ ƒe tiatia nɔ te ɖe nu geɖe dzi, siwo dometɔ aɖewoe nye ʋumenugbagbeviɣidɔ ƒe ƒomevi, ƒe si nèxɔ, kple wò lãmesẽ bliboa.

Aleke ʋumenugbagbeviɣidɔ dzɔnae?

Ʋumenugbagbeviɣidɔ dzea egɔme tso ƒumeŋuɖui , si nye míaƒe ƒuwo ƒe akpa falɛfalɛ si le abe ƒumeŋuɖui ene la me. Afi siae wowɔa ʋumenugbagbevi siwo míaƒe ŋutilã hiã le. Menye ɖeko ʋumenugbagbevi siawo dzɔna zi ɖeka ko o, ke wotoa akpa vovovowo me hafi tsina bliboe. Ʋumenugbagbevi siwo le lãmesẽ me, siwo tsi nyuie la ƒomevi etɔ̃e li:

• Ʋumenugbagbevi dzĩwo : Esiawoe tsɔa oxygen kple nu vevi bubuwo yia míaƒe ŋutilã katã me.
• Ʋumenugbagbevi ɣiwo : Woƒe dɔe nye be woawɔ avu kple dɔlékuiwo.
• Ʋumenugbagbevi dzĩwo : Esiawo kpena ɖe ʋu ŋu.

Ʋumenugbagbevi siawo katã dzea egɔme tso lãmenugbagbevi tɔxɛ siwo woyɔna be hematopoietic stem cells gbɔ. Emegbe lãmenugbagbevi siawo ma ɖe hatsotso eve me: myeloid cells kple lymphoid cells. Ne esiawo tsi nyuie la, lãmenugbagbevi tsitsi siwo dzɔnae nye:

• Myeloid lãmenugbagbeviwo (`(Myeloid lãmenugbagbeviwo)`) .Wona ʋumenugbagbevi dzĩwo, ʋumenugbagbevi dzĩwo, kple ʋumenugbagbevi ɣi ƒomevi aɖewo (basophils, eosinophils , kple neutrophils) dona.
• Lãmenugbagbevi siwo me ʋu sina tona naa ʋumenugbagbevi ɣi ƒomevi bubuwo (ʋumenugbagbevi dzĩwo) kple dzɔdzɔme lãmenugbagbevi siwo wua ame la dona.

Gake, le amesi ŋu ʋumenugbagbeviɣidɔ le gome la, ʋumenugbagbevi siawo siwo le tsitsim dometɔ ɖeka dzea mama gɔme kabakaba eye womate ŋu aɖu wo dzi o . Míeyɔa lãmenugbagbevi siawo siwo mesɔ o be "ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo." Ʋumenugbagbeviɣidɔlékui siawo xɔa teƒe le ƒumeŋuɖui me, eye woxea teƒe si ʋumenugbagbevi dzĩwo, lãmenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo le lãmesẽ me la xena.

Aleke ʋumenugbagbeviɣidɔ gblẽa nu le wò ŋutilã ŋui?

Bu nusi dzɔna ne ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo sɔ gbɔ akpa eye lãmenugbagbevi siwo le lãmesẽ me ʋɛ akpa la ŋu kpɔ. Esia fɔ biabia geɖe ɖe te:

• Ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo mewɔa naneke be wò ŋutilã nanɔ lãmesẽ me o.
• Esi ʋumenugbagbevi dzĩwo yɔa ƒumeŋuɖui me ta la, teƒe mele ʋumenugbagbevi siwo le lãmesẽ me be woatsi ahatsi nyuie o .
• Eyata ŋutilãa mewɔa ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣi siwo le lãmesẽ me, kple ʋumenugbagbevi dzĩwo wòsɔ gbɔ be woate ŋu aƒo ƒu ɖe ʋua me o.
• Esia wɔe be wò ŋutinuwo kple lãmekawo mekpɔa oxygen si sɔ o. Wò ŋutilã mate ŋu awɔ avu kple dɔlékuiwo alo axe ʋu ne ʋu le dodom le ŋuwò o.

Ʋumenugbagbeviɣidɔ ƒomevi vevi kawoe?

Ʋumenugbagbeviɣidɔ ƒomevi vevi ene li eye eƒe ƒomevi sue geɖewo li. Ðɔktawo nɔa te ɖe alesi dɔlélea kaka kabakabae kple nenye be ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo dzɔ tso myeloid alo lymphoid cells me nu.

To dɔlélea ƒe ŋgɔyiyi kabakaba me

• Ʋumenugbagbeviɣidɔ sesẽ : Le ʋumenugbagbeviɣidɔ sia ƒomevi me la, lãmenugbagbeviwo mãna kabakaba ŋutɔ, eye dɔlélea yia edzi kabakaba. Ne ʋumenugbagbeviɣidɔ sesẽ aɖe le ŋuwò la, àdze dɔ gɔme le kwasiɖa ʋɛ aɖewo megbe. Esia ate ŋu ade ame ƒe agbe afɔku me, eyata ele be woadze edada gɔme enumake . Ʋumenugbagbeviɣidɔ sesẽe nye kansa ƒomevi si bɔ wu le ɖevi suewo me.
• Ʋumenugbagbeviɣidɔ si nɔa anyi didi : Le ƒomevi sia me la, ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo wɔa nu abe lãmenugbagbevi siwo metsi o ene ɣeaɖewoɣi eye ɣeaɖewoɣi abe lãmenugbagbevi siwo tsi ene. Lãmenugbagbevi aɖewo tsina vaseɖe afi aɖe eye wowɔa woƒe dɔ vaseɖe afi aɖe – gake menye abe lãmenugbagbevi siwo le lãmesẽ me ene o. Dɔlélea yia edzi blewu wu ʋumenugbagbeviɣidɔ sesẽ. Ne ʋumenugbagbeviɣidɔ si nɔa anyi didi le ŋuwò la, ɖewohĩ dzesi gã aɖeke manɔ ŋuwò o ƒe geɖe. Ebɔ ɖe ame tsitsiwo me wu ɖeviwo.

Le lãmenugbagbevi ƒomevi nu

• Myelogenous alo Myeloid leukemia : Esia dzɔna tso myeloid lãmenugbagbeviwo me. Myeloid cells siwo sɔ la wɔa ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo.
• Ʋumenugbagbeviɣidɔ si tso ʋumenugbagbeviɣidɔ me: Lãmenugbagbevi siwo me ʋumenugbagbeviɣidɔ le ye wɔa esia. Ʋumenugbagbevi ɣi siwo ʋumenugbagbevi dzĩ siwo sɔ wɔna la nye míaƒe ŋutilã ƒe dɔlélenutsiŋutete ƒe akpa vevi aɖe ŋutɔ.

Ʋumenugbagbeviɣidɔ ƒomevi vevi ene

Ne wotsɔ hatsotso eve siawo ƒo ƒui la, wode dzesi ʋumenugbagbeviɣidɔ ƒomevi vevi ene:

1. Acute Lymphocytic Leukemia (ALL) : Esiae nye ʋumenugbagbeviɣidɔ ƒomevi si bɔ wu si wokpɔna le ɖeviwo kple sɔhɛ tsitsiwo (siwo xɔ ƒe 39) ŋu. Ke hã, ate ŋu adzɔ le ame tsitsi siwo xɔ ƒe ɖesiaɖe hã dzi.

2. Acute Myelogenous Leukemia (AML) : Esiae nye ʋumenugbagbeviɣidɔ sesẽ ƒomevi si bɔ wu le ame tsitsiwo me. Ebɔ ɖe amesiwo xɔ wu ƒe 65. Ate ŋu adzɔ le ɖevi suewo hã me.

3. Chronic Lymphocytic Leukemia (CLL) : Esiae nye ʋumenugbagbeviɣidɔ ƒomevi si bɔ wu le ame tsitsiwo dome (vevietɔ amesiwo xɔ wu ƒe 65). Le CLL me la, dzesiawo ate ŋu axɔ ƒe geɖe hafi woadze.

4. Chronic Myelogenous Leukemia (CML) : Esia hã bɔ ɖe ame tsitsiwo me wu (vevietɔ amesiwo xɔ wu ƒe 65), gake ate ŋu adze ame tsitsi siwo xɔ ƒe ɖesiaɖe dzi. Ƒã ŋutɔ le ɖevi suewo me. Le CML me la, dzesiawo ate ŋu axɔ ƒe geɖe hafi woadze.

Aleke gbegbee ʋumenugbagbeviɣidɔ bɔe?

Le akɔntabubu siwo le dukɔ aɖewo me le xexeame godoo nu la, wobua ʋumenugbagbeviɣidɔ be enye kansa si bɔ wu ewolia. Togbɔ be ate ŋu adze ame sia ame dzi hã la, wokpɔe be ƒuƒoƒo aɖewo le afɔku me vie:

• Ame siwo xɔ tso ƒe 65 va ɖo ƒe 74.
• Ŋutsuwo.
• Le to aɖewo dome (e.g. Caucasians/yevuwo - esiawo nye duta nyatakakawo).

Ame geɖe bua ʋumenugbagbeviɣidɔ be enye dɔléle si ɖevi suewo ko dzea edzi. Gake ʋumenugbagbeviɣidɔ ƒomevi aɖewo bɔ ɖe ame tsitsiwo me wu. Togbɔ be ʋumenugbagbeviɣidɔ mebɔ ɖe ɖeviwo me o hã la, eyae nye kansa ƒomevi si bɔ ɖe ɖeviwo kple sɔhɛ tsitsiwo me wu.

Nukawoe nye ʋumenugbagbeviɣidɔ ƒe dzesiwo?

Dzesiawo nɔ te ɖe ʋumenugbagbeviɣidɔ ƒe ƒomevi dzi. Le kpɔɖeŋu me, ne ʋumenugbagbeviɣidɔ si nɔa anyi didi le ŋuwò la, ɖewohĩ dzesi gã aɖeke madze le ŋuwò le eƒe gɔmedzedze o.

Ʋumenugbagbeviɣidɔ ƒe dzesi siwo bɔ dometɔ aɖewoe nye esi:

• Ðeɖiteameŋu kpata , ɖeɖiteameŋu bɔbɔe.
• Asrã alo fifia le zã me .
• Dɔlékuiwo xɔxɔ enuenu .
• Yagbɔgbɔ sesẽ .
• Ŋutilã si ƒe ŋutigbalẽ le ɣie .
• Lolo dzi ɖeɖe kpɔtɔ susu aɖeke manɔmee.
• Ƒu/ƒunukpeƒewo ƒe vevesese alo ƒunukpeƒetetedɔ.
• Vevesese alo seselelãme be yeyɔ fũ le akɔta le miame.
• Lãmetsiŋusẽ siwo vuvu le kɔ, abɔta, akɔta, alo ƒodo me, dɔgbo alo aklã si lolo.
• Abi kple ʋu si dona le ame ŋu bɔbɔeƲu si dona le ŋɔti me, aɖu siwo me ʋu le dodom le, ʋuʋudedi si le abe ʋuʋudedi suesuesue siwo le ŋutigbalẽa ŋu ene (petechiae) alo teƒe siwo le dzo dam/yibɔ le ŋutigbalẽa ŋu.

Ne dzesi siawo dometɔ ɖeka alo esi wu nenema le ŋuwò la, mefia kokoko be ʋumenugbagbeviɣidɔ le ŋuwò o. Gake ne dzesi siawo le ŋuwò la, ele vevie ŋutɔ be nàyi ɖɔkta gbɔ aɖaɖo aɖaŋu na wò.

Nukawoe hea ʋumenugbagbeviɣidɔ vɛ?

Ʋumenugbagbeviɣidɔ dzea egɔme kple tɔtrɔ (trɔtrɔ) le lãmenugbagbevi ɖeka ƒe DNA me le wò ƒumeŋuɖui me. DNA le abe "mɔfiamewo ƒe hatsotso" ene. DNA sia gblɔa ɣeyiɣi si lãmenugbagbevi aɖe tsi, ale si wòawɔ, kple ɣeyiɣi si wòaku.

Le tɔtrɔ sia ta la, ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo tea mama atraɖii. DNA sia si trɔ le lãmenugbagbevi ɖesiaɖe si dona tso lãmenugbagbevi gbãtɔ si wogbugbɔ trɔ la me.

Dzɔdzɔmeŋutinunyalawo menya nusita tututu lãmenugbagbevi siawo trɔna haɖe o, gake wode dzesi tɔtrɔ aɖewo siwo bɔ siwo wokpɔna le amesiwo ŋu ʋumenugbagbeviɣidɔ ƒomevi vovovowo le ŋu.

Amekawoe le afɔku gã me be woaxɔ ʋumenugbagbeviɣidɔ?

Amesiame ate ŋu axɔ ʋumenugbagbeviɣidɔ. Gake numekukuwo ɖee fia be nu aɖewo ate ŋu ana afɔkua nadzi ɖe edzi. Nu siawo dometɔ aɖewoe nye:

• Esi nèxɔ kansa ƒe atikewɔwɔ va yi : Ne èxɔ kansa ƒe atikewo abe keklẽŋusẽdɔdamɔnu alo atikewɔmɔnu ene la, anɔ eme be ʋumenugbagbeviɣidɔ ƒomevi aɖewo adze dziwò.
• Atamanono : Ne atamanolae nènye alo atamanonoe nènona la, ke afɔku le eme be nàxɔ ʋumenugbagbeviɣidɔ sesẽ (AML).
• Atike siwo wozãna le dɔwɔƒewo ƒe amedzidzedze : Benzene kple formaldehyde nye atike siwo hea kansa vɛ. Woate ŋu akpɔ wo le xɔtunuwo kple aƒeme atikewo me (plastik, rababa, amadede, nudzodzoeviwutike, atike, atike siwo wotsɔna klɔa nu, adzalẽ, shampoo, dzadzɛnyenyetikewo).
• Domenyiŋusẽfianu aɖewo : Domenyiŋusẽfianu ƒe nɔnɔmewo abe neurofibromatosis, Klinefelter ƒe dɔléle, Schwachman-Diamond ƒe dɔléle, kple Down ƒe dɔléle ene ate ŋu ana afɔkua nadzi ɖe edzi.
• Ʋumenugbagbeviɣidɔ ƒe ƒome ŋutinya : Numekukuwo ɖee fia be ʋumenugbagbeviɣidɔ ƒomevi aɖewo ate ŋu anɔ ƒomewo me. Gake zi geɖe la, esi ʋumenugbagbeviɣidɔ le wò ƒomea me tɔ aɖe ŋu ta la, mefia be ʋumenugbagbeviɣidɔ adze wò ŋutɔ alo wò ƒomea me tɔ bubu aɖe dzi o. Gblɔe na wò ɖɔkta ne domenyiŋusẽfianu ƒe dɔléle aɖe le wò alo wò ƒomea me tɔ aɖe ŋu. Woate ŋu aɖo aɖaŋu be woado domenyiŋusẽfianu kpɔ atsɔ akpɔ afɔku si le ŋuwò.

Aleke wokpɔa ʋumenugbagbeviɣidɔ?

Ʋudodokpɔ si wowɔna edziedzi me tsonu ate ŋu ana wò ɖɔkta nakpɔe be ʋumenugbagbeviɣidɔ sesẽ alo esi nɔa anyi didi ate ŋu anɔ ŋuwò, eye be ehiã be nàgawɔ dodokpɔ bubuwo. Alo, ne ʋumenugbagbeviɣidɔ ƒe dzesiwo le ŋuwò la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dodokpɔ vovovowo.

Dodokpɔ siwo wowɔna tsɔ dea dzesi dɔlélea ate ŋu anye:

• Lãmesẽdodokpɔ : Ðɔktaa abia wò dzesiwo eye wòase wò ŋutilã be ʋuka siwo vuvu, dɔgbo si lolo, alo aklã hã le ŋuwò. Woalé ŋku ɖe ʋu le dodom le aɖuawo ŋu alo vuvu hã ŋu. Woate ŋu adi ŋutigbalẽ ƒe ʋuʋudedi hã, si ate ŋu anye dzĩ, aŋutiɖiɖi, alo aŋutiɖiɖi, eye wòdo ƒome kple ʋumenugbagbeviɣidɔ.
• Ʋu Xexlẽme Blibo (CBC) : Ʋudodokpɔ sia ate ŋu ana wò ɖɔkta nanya ne wò ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo ƒe xexlẽme mesɔ o. Ne ʋumenugbagbeviɣidɔ le ŋuwò la, anɔ eme be wò ʋumenugbagbevi ɣiwo ƒe xexlẽme asɔ gbɔ sã wu alesi wòle dzɔdzɔmee.
• Ʋumenugbagbeviɣiwo dodokpɔ : Wò ɖɔkta ate ŋu aɖe gbe hã be woado ʋu bubuwo kpɔ be woatsɔ adi dzesi siwo fia be ʋumenugbagbeviɣidɔ alo ʋumenugbagbeviɣidɔ ƒomevi aɖe koŋ. Flow cytometry kple peripheral blood smear nye dodokpɔ bubu siwo wò ɖɔkta ate ŋu abia.
• Ƒumeŋuɖui (alo ƒumeŋuɖui ƒe ʋuʋu) : Wò ɖɔkta ate ŋu awɔ dodokpɔ sia ne wò ʋumenugbagbevi ɣiwo ƒe xexlẽme mesɔ o. Le dodokpɔ sia me la, wotsɔa aŋe didi aɖe dea wò ƒumeŋuɖui me (zi geɖe le wò akɔtaƒu me) be woaɖe tsi aɖe ɖa. Emegbe wodoa kpɔɖeŋua kpɔna le dodokpɔxɔ me be woakpɔe ɖa be ʋumenugbagbeviɣidɔlékuiwo le eme hã. Ƒumeŋuɖui ŋuti numekuku ate ŋu anya lãmenugbagbevi siwo mesɔ o ƒe alafa memamã si tututu le wò ƒumeŋuɖui me, si ate ŋu akpe ɖe ŋuwò nàɖo kpe ʋumenugbagbeviɣidɔ ƒe dzesi dzi.
• Nɔnɔmetatawo ɖeɖe kple dodokpɔ bubuwo : Ne wò dzesiwo ɖee fia be ʋumenugbagbeviɣidɔ gblẽ nu le wò ƒuwo, ŋutinuwo, alo lãkusiwo ŋu la, wò ɖɔkta ate ŋu abia be woawɔ akɔta ƒe X-ray, CT scan, alo MRI scan. Gake nɔnɔmetatawo dodokpɔ siawo mate ŋu akpɔ ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo o.
• Lumbar puncture (alo spinal tap) : Ðɔkta ate ŋu ado aklã me tsi ƒe kpɔɖeŋu aɖe akpɔ be ʋumenugbagbeviɣidɔ kaka ɖe tsi si ƒo xlã ahɔhɔ̃a kple aklã ƒe ka (aklã me tsi) me hã.

Aleke wodaa ʋumenugbagbeviɣidɔe?

Ʋumenugbagbeviɣidɔ dada nɔ te ɖe ʋumenugbagbeviɣidɔ si ƒomevi nèxɔ, ƒe si nèxɔ kple wò lãmesẽ bliboa, kple ne ʋumenugbagbeviɣidɔa kaka ɖe ŋutinu alo lãkusi bubuwo me dzi.

Dɔdamɔnu siwo bɔ ate ŋu anye esiwo gbɔna dometɔ ɖeka alo esi wu nenema:

• Atikewɔwɔ (`(Atikewɔwɔ)`) .: Esiae nye ʋumenugbagbeviɣidɔ ƒe atike si bɔ wu. Ezãa atikewo (atikewo) tsɔ wua ʋumenugbagbeviɣidɔlékuiwo alo xea mɔ na wo be woagama o. Le atikewɔwɔ me la, àte ŋu axɔ atike siawo (atikewo) abe atikekui ene, abe atike si wodo ɖe ʋuka me ene, alo abe atike si wodo ɖe ŋutigbalẽ te ene. Zi geɖe la, wotsɔa atikewɔmɔnu kpena ɖe atike vovovowo ŋu.
• Dɔlélenutsiŋutete ƒe dɔdamɔnu (alo dɔlékuiwutikewo) : Dɔdamɔnu sia zãa atike tɔxɛwo tsɔ doa ŋusẽ wò ŋutilã ƒe ametakpɔnu—si nye dɔlélenutsiŋutete—be wòawɔ avu kple ʋumenugbagbeviɣidɔ. Dɔlélenutsiŋutete ƒe dɔdamɔnu kpena ɖe wò dɔlélenutsiŋutete ŋu wòdea dzesi kansa lãmenugbagbeviwo eye wòwɔa dɔlélenutsiŋutete ƒe lãmenugbagbevi geɖe wu be woawɔ avu kpli wo.
• Atikewɔwɔ si woɖo taɖodzinu na : Dɔdamɔnu sia zãa atike siwo wowɔ be woadze ʋumenugbagbeviɣidɔ ƒe akpa aɖewo koŋ dzi (abe protein alo domenyiŋusẽfianu ene). Akpa siawoe nana ʋumenugbagbeviɣidɔlékuiwo ƒe xexlẽme sɔ gbɔ wu ʋumenugbagbevi siwo sɔ. Atikewɔwɔ si woɖo taɖodzinu na ate ŋu ana ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo nagamam o, atso lãmenugbagbeviawo ƒe ʋu me, alo awu wo tẽ. Atikewɔwɔ si woɖo taɖodzinu na megblẽa nu le lãmenugbagbevi siwo sɔ ŋu boo o. Atike siawo ƒe kpɔɖeŋu aɖewoe nye dɔlékuiwutike siwo nye monoclonal antibodies kple tyrosine kinase inhibitors.
• Kekeli ƒe atikewɔwɔ : Atikewɔwɔ sia zãa keklẽŋusẽ alo X-ray siwo ŋu ŋusẽ geɖe le tsɔ wua ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo alo xea mɔ na wo be woagatsi o. Le atikewɔwɔ me la, mɔ̃ aɖe ate ŋu ahe keklẽa ayi afisi tututu kansadɔlékuiawo le alo amae ɖe ŋutilã bliboa me. Woate ŋu ana keklẽŋusẽ si le ŋutilã bliboa me hafi woado ʋumenugbagbeviɣidɔ.
• Hematopoietic cell transplant (alo `stem cell` alo `bone marrow transplant`) : Le atikewɔwɔ sia me la, wotsɔa ʋumenugbagbevi yeye siwo le lãmesẽ me ɖɔlia lãmenugbagbevi siwo wɔa ʋu si me kansa le siwo dome gblẽ to atikewɔmɔnu kple/alo keklẽŋusẽdɔdamɔnu me. Wò ɖɔkta ate ŋu axɔ lãmenugbagbevi siawo siwo le lãmesẽ me le asiwò hafi woawɔ atike na wò kple keklẽŋusẽdɔdamɔnu, alo woate ŋu atso amesi na wò gbɔ. Lãmenugbagbevi yeye siawo siwo le lãmesẽ me ma eye wowɔa ƒumeŋuɖui kple ʋumenugbagbevi yeyewo (ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩ siwo wò ŋutilã hiã).
• Chimeric Antigen Receptor (CAR) T-cell therapy : Esia nye atike yeye ƒomevi aɖe. Ebia be nàxɔ wò ŋutilã ŋutɔ ƒe T-lãmenugbagbevi siwo tsia tre ɖe dɔlékuiwo ŋu (dɔlélenutsiŋutete ƒe lãmenugbagbevi ƒomevi aɖe si woyɔna be T-cell alo T-lymphocyte), agbugbɔ wo awɔ avu kple ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo, eye emegbe nàgatsɔ wo ade wò ŋutilã me ake.

Mɔnukpɔkpɔ ate ŋu asu asiwò hã be nàkpɔ gome le dɔdamɔnu dodokpɔ siwo doa kansadɔdamɔnu yeyewo kpɔna me. Ƒo nu tso viɖe kple kuxi siwo le gomekpɔkpɔ le dodokpɔ sia tɔgbe me ŋu na wò ɖɔkta.

Afɔ kawoe nye ʋumenugbagbeviɣidɔdada ƒe afɔɖeɖewo?

Le wò atikewɔwɔ ƒe ɖoɖo nu la, àte ŋu axɔ ʋumenugbagbeviɣidɔ ƒe atike atraɖii hena ɣeyiɣi didi aɖe, alo àte ŋu axɔ atike na wò le akpa vovovowo me. Zi geɖe la, akpa etɔ̃e nɔa atikewɔwɔ si wowɔna ɖe ɖoɖo nu me. Taɖodzinu aɖe koŋ le akpa ɖesiaɖe si.

1. Induction therapy : Esia ƒe taɖodzinue nye be wòawu ʋumenugbagbeviɣidɔ ƒe lãmenugbagbevi geɖe alesi nàte ŋui le wò ʋu kple ƒumeŋuɖui me eye wòana nànɔ tsɔtsɔke me. Le tsɔtsɔke me la, wò ʋumenugbagbeviɣiwo trɔna yia nɔnɔme si sɔ me, womegakpɔa wò ʋumenugbagbeviɣidɔlékuiwo le wò ʋu me o, eye dɔlélea ƒe dzesiwo kple dzesiwo katã nu yina. Zi geɖe la, induction therapy xɔa abe kwasiɖa ene va ɖo ade ene.

2. Consolidation therapy (si woyɔna hã be ``(Intensification)``) : Esia ƒe taɖodzinue nye be woatsrɔ̃ ʋumenugbagbeviɣidɔ ƒe lãmenugbagbevi ɖesiaɖe si susɔ, si womate ŋu ade dzesii o. Esia ate ŋu akpe ɖe ame ŋu be kansa la nagatrɔ ava o. Zi geɖe la, wowɔa atike sia le ɣeyiɣi vovovowo me, le ɣleti ene va ɖo ade me.

3. Beléle na dɔdamɔnu : Esia ƒe taɖodzinue nye be wòatsrɔ̃ ʋumenugbagbeviɣidɔ ƒe lãmenugbagbevi ɖesiaɖe si ate ŋu asusɔ le atikewɔwɔ ƒe ɣeyiɣi eve gbãtɔawo megbe eye woaxe mɔ na kansa la be wòagatrɔ ava (gbugbɔgadzɔ). Woyia atikewɔwɔ sia dzi abe ƒe eve ene.

Ne ʋumenugbagbeviɣidɔa gadze la, wò ɖɔkta ate ŋu agbugbɔ adze wò atikewɔwɔ gɔme alo atrɔe.

Nuka ƒomevie mate ŋu ado tso eme ne wokpɔ ʋumenugbagbeviɣidɔ le ame ŋu vɔ?

Esesẽ be woagblɔ ʋumenugbagbeviɣidɔ ƒe ŋgɔdonya pɛpɛpɛ, elabena amesiame ƒe nuteƒekpɔkpɔ to vovo. Nusi ado tso eme nɔ te ɖe nu geɖe dzi:

• Domenyiŋusẽfianu ƒe masɔmasɔ alo tɔtrɔ (`(Mutations)`) : Dzɔdzɔmeŋusẽ ƒe tɔtrɔ le ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo me nye nu vevitɔ kekeake si ɖea emetsonua fiana.
• Ʋumenugbagbeviɣidɔ ƒomevi : Ʋumenugbagbeviɣidɔ ƒomevi aɖewo me tsonu nyo wu bubuwo.
• Ʋumenugbagbeviɣi ƒe xexlẽme le dɔlélea didi me : Ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo ƒe xexlẽme si nɔa anyi le dɔlélea kpɔkpɔ me hã ate ŋu akpɔ ŋusẽ ɖe wò dɔwɔwɔ me tsonu dzi.
• Ƒe : Le goawo katã me la, zi alesi nènye ɖekakpui ne wokpɔ dɔlélea le ŋuwò la, zi nenemae emetsonua anyo wu.
• Lãmesẽ ƒe nɔnɔme : Le goawo katã me la, zi alesi nèle lãmesẽ me ne wokpɔ dɔlélea le ŋuwò la, zi nenemae emetsonua anyo wu.
• Alesi wowɔa nui ɖe atikewɔwɔ ŋu : Ɣeyiɣi si wòxɔna hafi kansa la yia tsɔtsɔke me (`(Remission)`) ate ŋu ana woakpɔ alesi gbegbe atikewɔwɔa kpɔ dzidzedzee.
• Ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo ƒe anyinɔnɔ le lãmekawo ƒe dɔwɔwɔ me : Ne lãmenugbagbeviwo le wò aklã me tsi me la, ate ŋu asesẽ be nàda wo.

Mlɔeba la, wò ɖɔktae nye ame nyuitɔ kekeake si ase alesi wò kansa le nu gblẽm le ŋuwò etɔxɛe gɔme. Bia wo tso atikewɔwɔ me tsonu ŋu.

Ðe woate ŋu ada ʋumenugbagbeviɣidɔ keŋkeŋa?

Naneke meli si woyɔna be "atike blibo" na ʋumenugbagbeviɣidɔ o. Gake ema mefia be ame aɖewo meyia ɣeyiɣi didi ƒe tsɔtsɔke me o. Ne woda gbe le ʋumenugbagbeviɣidɔ ŋu la, efia be kansa la nu yi, magatrɔ ava o, eye mehiã be woawɔ atike bubu aɖeke nɛ o. Gake le ʋumenugbagbeviɣidɔ gome la, esesẽ be míagblɔ nya sia kple kakaɖedzi.

Le go bubu me la, ne woɖee ɖa ɣeyiɣi didi la , efia be dzesi aɖeke mele kansa la ŋu o, ne wowɔ atike nɛ alo womewɔe nɛ o. Dɔléle sia ate ŋu anɔ anyi tso kwasiɖa ʋɛ aɖewo va ɖo ƒe geɖe. Ðewohĩ ʋumenugbagbeviɣidɔa magatrɔ ava gbeɖe o. Ne egatrɔ gbɔ la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàzã atike yeyewo be nàɖee ɖa.

Wò atikewɔlawo ƒe ƒuƒoƒo ate ŋu aɖo biabia si nye, "Ðe woda nye ʋumenugbagbeviɣidɔa?" Woalé ŋku ɖe wò lãmesẽ ŋu nyuie eye woawɔ atikewɔwɔ ƒe ɖoɖo si asɔ na wò.

Nya kawoe wòle be nàbia wò ɖɔkta?

Do ŋusẽ ɖokuiwò to alesi nàte ŋui sɔsrɔ̃ tso alesi wò kansa ƒe dzesiwo kpɔa ŋusẽ ɖe dziwò koŋ ŋu. Anyo be nàŋlɔ nuwo ɖi eye nàkplɔ xɔ̃wò aɖe ɖe asi ne èyi wò ɖɔkta gbɔ. Mègavɔ̃ be yeabia nya o.

Nya aɖewo siwo nàte ŋu abia:

• Ʋumenugbagbeviɣidɔ ka ƒomevie le ŋunye? Lãmenugbagbevi ka ƒomevie le eme? Ðe wònye kansa si le tsitsim kabakaba loo alo esi le tsitsim blewua?
• Aleke gbegbee wokpɔ ʋumenugbagbeviɣidɔ dze sii kaba?
• Atikewɔwɔmɔnu kawoe le asinye?
• Viɖe kple afɔku kawoe le atikewɔwɔmɔnu ɖesiaɖe me?
• Atikewɔwɔ ƒe ɖoɖo kae nyo nam wu? Nu ka ta?
• Ɣekaɣie wòle be woadze atikewɔwɔ gɔme?
• Ɣeyiɣi didi kae atikewɔwɔ (kple atikewɔwɔ ƒe akpa ɖesiaɖe) xɔa?
• Ɣeyiɣi didi kae wòahiã be manɔ kɔdzi?
• Nukawoe nye atikewɔwɔ ƒe nugbegblẽ le ame ŋu? Nukae woate ŋu awɔ atsɔ axe mɔ ɖe wo nu alo aɖe wo dzi akpɔtɔ?
• Ke ne medi be madzi vi ɖe? Tiatia kawoe li be makpɔ nye vidzidzi ta?
• Nukae nye agbetsitsi ƒe agbɔsɔsɔme le nye ʋumenugbagbeviɣidɔ ƒomevi me?
• Ðe wòle be makpɔ gome le dɔdamɔnu dodokpɔ aɖe mea?

Afikae mate ŋu akpɔ nyatakaka kple kpekpeɖeŋu bubuwo tso ʋumenugbagbeviɣidɔ ŋu le?

Ne èdi be yeanya nu geɖe tso ʋumenugbagbeviɣidɔ ƒe dɔdamɔnu dodokpɔwo ŋu la, àte ŋu ayi dukɔwo dome nyatakakadzraɖoƒewo (e.g., Leukemia & Lymphoma Society, National Cancer Institute, American Cancer Society). Azɔ hã, bia wò ɖɔkta tso nutoa me ƒe dɔwɔnuwo kple kpekpeɖeŋunahawo ŋu.

Kansa ƒe dɔléle ɖesiaɖe si woakpɔ la doa vɔvɔ̃ na ame. Gake ʋumenugbagbeviɣidɔ ƒe dzesi ate ŋu ado vɔvɔ̃ na ame wu. Ne dɔdzẽ aɖeke meli woaɖe ɖa o la, ate ŋu asesẽ be woanya alesi atikewɔwɔ ƒe nuteƒekpɔkpɔa anɔ kple alesi etsɔme ahe vɛ. Ðo ŋku edzi be ʋumenugbagbeviɣidɔ menye nusi sɔ na amesiame o. Wò atikewɔwɔ kple mɔnukpɔkpɔ si li be wò dɔlélea nu sẽ ɣeyiɣi didi la nɔ te ɖe nu geɖe dzi. Ame aɖeke mate ŋu agblɔ nusi ado tso eme ne mese wò lãmesẽ kple ʋumenugbagbeviɣidɔ, si me ʋumenugbagbeviɣidɔ ƒe lãmenugbagbeviwo ƒe nɔnɔmewo hã le gɔme o. Ƒo nu kple wò ɖɔkta tso nusi ʋumenugbagbeviɣidɔ ƒe dzesi fia na wò ŋu.

Nya kpui siwo dzi wòle be míaɖo ŋkui

Enyo, eyata mele mɔ kpɔm be susu nyui aɖe le asiwò le ʋumenugbagbeviɣidɔ ŋu tso nusiwo me míedzro me. Nu vevi aɖewo siwo dzi wòle be woaɖo ŋkui lae nye esi:

• Ʋumenugbagbeviɣidɔ nye ʋu me kansa , si tsoa lãmenugbagbevi siwo mesɔ o ƒe tsitsi le ƒumeŋuɖui me si dzi womeɖu o gbɔ.
• Esia ƒomevi vevi eve li: dɔléle sesẽ kple esi nɔa anyi didi, kple myeloid kple lymphoid .
• Dzesiawo to vovo, eye ate ŋu anye ɖeɖiteameŋu kpata, dɔlékuiwo xɔxɔ enuenu, kple abi ƒe ƒoƒo bɔbɔe .
• Togbɔ be womenya nusi tututu gbɔ wòtso o hã la, domenyiŋusẽfianu ƒe tɔtrɔ, atike aɖewo, kple kansa dada va yi ate ŋu anye nusiwo ate ŋu ahe afɔku vɛ.
• Ʋudodokpɔ kple ƒumeŋuɖui me ɖeɖe koŋue wokpɔa dɔlélea le .
• Atikewɔwɔ ƒe mɔnu geɖewo li (abe ``Chemotherapy'', ``Immunotherapy'', ``Targeted therapy''), siwo nɔ te ɖe dɔnɔa kple dɔlélea ƒe nɔnɔme dzi.
• Le esi teƒe be míaƒo nu tso atike si woada keŋkeŋ ŋu la, míate ŋu akpɔ mɔ be eƒe dɔlélea nu ayi ɣeyiɣi didi aɖe .
• Mègavɔ̃ be yeabia nyawo ahaxɔ nyatakakawo tso wò ɖɔkta gbɔ o . Menye wò ɖeka koe o.

Míele mɔ kpɔm be nyatakaka siawo aɖe vi na wò. Nɔ lãmesẽ me!

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