Ðewohĩ ènya alesi gbegbe calcium le vevie be míaƒe ƒuwo kple aɖuwo nasẽ ŋu xoxo. Gake ènya be ele be calcium, si nye tomenu vevi aɖe, hã nanɔ agbɔsɔsɔ si sɔ me be ʋukawo, lãmekawo, kple lãmekawo nanɔ lãmesẽ mea? Ne wò ʋudodokpɔ me tsonu siwo nèdo nyitsɔ laa ɖee fia be wò calcium sɔ gbɔ akpa alo bɔbɔ akpa la, ke ɖewohĩ wò ɖɔkta ɖe gbe be woagado ʋu tɔxɛ bubu kpɔ. Emae nye dodokpɔ si ŋu míele nu ƒom tsoe egbea, si dzidzea wò parathyroid hormone (PTH) ƒe agbɔsɔsɔ.
Kpuie ko la, nukae nye parathyroid hormone (PTH)?
Lãmetsi sue ene ŋutɔ le míaƒe kɔ me. Woƒe lolome anɔ abe peas suewo ene. Esiawoe nye nusiwo míeyɔna be
parathyroid glands . Lãmenugbagbevi siawo wɔa lãmetsi si woyɔna be parathyroid hormone, alo PTH. Dɔ vevitɔ si lãmetsi sia wɔnae nye be wòakpɔ calcium ƒe agbɔsɔsɔ si le míaƒe ʋu me dzi. Enye ɖoɖo wɔnuku aɖe ŋutɔ. Bu eŋu ale:
- Ne calcium ƒe agbɔsɔsɔ le wò ʋu me ɖiɖi la , lãkusi siawo ɖea lãmetsi si nye PTH ɖea wò ʋu me. PTH sia yia ɖaƒoa calcium nu ƒu tso wò ƒuwo kple ayiku me eye wònana wò calcium ƒe agbɔsɔsɔ gaɖoa eƒe nɔnɔme nyuitɔ me.
- Ne calcium ƒe agbɔsɔsɔ le wò ʋu me dzi ɖe edzi la , lãkusi siawo dzudzɔa PTH lãmetsiŋusẽa dodo. Esia kpɔa calcium ƒe agbɔsɔsɔ si le wò ʋu me dzi.
Eyata, wò PTH ƒe agbɔsɔsɔ dzidzedze kpena ɖe ɖɔktawo ŋu ŋutɔ be woanya nusi tututu na wò ʋu me calcium le ɖiɖim alo le dzidzim ɖe edzi.
Nukatae ɖɔkta aɖe kafu dodokpɔ sia?
Nu vevitɔe nye be nànya nenye be nusi gbɔ wò ʋu me calcium ƒe agbɔsɔsɔ si mesɔ o tso la nye kuxi si le parathyroid glands ƒe dɔwɔwɔ ŋu loo alo nu bubu aɖe si gbɔ wòtso. Ne wò PTH ƒe agbɔsɔsɔ sɔ kple wò calcium ƒe agbɔsɔsɔ la, efia be nusi gbɔ calcium ƒe agbɔsɔsɔ si mesɔ o tsoe nye nu bubu. Zi geɖe la, ne dzesi siwo gbɔna le ŋuwò la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàdo PTH dodokpɔ sia.
| Hypercalcemia - calcium ƒe dzidziɖedzi le ʋu me | Hypocalcemia - calcium si mebɔ o le ʋu me |
|---|
| Dɔgbo ƒe vevesese | Blanuiléle kple seselelãme ƒe tɔtrɔ enuenu |
| Tsikɔwuame si gbɔ eme | Lãmetsiwo ƒe ʋuʋu alo ʋuʋu (Spasms) . |
| Ehiã be nàɖe aɖuɖɔ enuenu | Asi, afɔ, kple nu ƒe ʋuʋu alo ʋuʋudedi |
| Aɖuɖɔtoe kple ʋuʋudedi | Dzi ƒe tsotso ƒe masɔmasɔ |
| Ɖeɖiteameŋu | |
| Ŋutilã kple ƒu ƒe vevesese | |
| Ayiku me kpewo | |
Ðe afɔku aɖewo le dodokpɔ sia mea?
Le nyateƒe me la,
afɔku ʋɛ aɖewo koe le eme. Abe alesi wòle le ʋudodokpɔ ɖesiaɖe gome ene la, àte ŋu ase veve aɖe le afisi wodo aŋea le. Àte ŋu akpɔ abi aɖewo hã le esia megbe. Ame aɖewo ate ŋu ase le wo ɖokui me be taɖuame vie le ʋudodo vɔ megbe. Gake esia sɔ ŋutɔ.
Viɖe gãtɔ kekeake si le dodokpɔ sia ŋue nye be enaa ɖɔktaa nyaa tututu nenye be wò ŋutilã le PTH lãmetsi si le dodom akpa alo le ʋɛ akpa.
Esia ate ŋu aɖo kpe parathyroid dɔléle aɖe dzi alo agbee. Emegbe mia kple wò ɖɔkta miate ŋu adi nu bubu siwo gbɔ wò calcium ƒe agbɔsɔsɔ si mesɔ o tsona.
Ðe wòhiã be nàdzra ɖo hafi adze dodokpɔa gɔmea?
Ẽ, wò ɖɔkta ate ŋu abia tso asiwò be nàdzudzɔ atike aɖewo alo vitamin (siwo kpena ɖe eŋu) nono ŋkeke si do ŋgɔ na dodokpɔa alo gbesigbe. Gake
mègadzudzɔ atike aɖeke nono gbeɖe ne mèbia wò ɖɔkta gbã o .
Nukae dzɔna le dodokpɔa wɔɣi kple emegbe?
Esia nye dɔdamɔnu bɔbɔe aɖe ŋutɔ. Woɖea ʋu sue aɖe tso ʋuka aɖe si le wò alɔnu me. Ame si le ʋua nom la atsɔ rababa aƒo xlã wò alɔnu gbã eye wòablae sesĩe. Ne èmimi wò alɔnu la, ʋukawo adze nyuie. Emegbe woazã aŋe sue aɖe atsɔ ahe ʋu sue aɖe ayi dodokpɔmɔ̃ me. Esia mehiã be woaɖe ʋu gbogbo aɖeke o. Ne woɖe ʋua la, woɖea aŋea ɖa eye wotsɔa aŋɔ sue aɖe sisina ɖe teƒea. Emegbe woɖoa ʋu sia ɖe dodokpɔxɔ aɖe be woado PTH, calcium, kple ɖewohĩ lãmetsiŋusẽ kple mineral bubuwo ƒe agbɔsɔsɔ kpɔ.
Aleke míase emetsonuwo gɔmee?
Ate ŋu axɔ ŋkeke ʋɛ aɖewo hafi dodokpɔa me tsonu natrɔ ava. Gake ɣeaɖewoɣi la, woate ŋu akpɔ emetsonuwo kaba wu, le dodokpɔxɔa kple ɖɔktaa ƒe nuhiahiãwo nu. Woɖea emetsonuwo fiana le picograms me le mililita ɖeka me (pg/mL). PTH ƒe didime si sɔ ate ŋu ato vovo vie tso dodokpɔxɔ ɖeka me yi bubu gbɔ. Lãmesẽ ƒe didime na `intact molecule` ƒomevi si nye PTH zi geɖe la nɔa
10 - 65 pg/mL dome.
Nu vevitɔe nye be nàƒo nu kple wò ɖɔkta godoo be nàse nusi tututu xexlẽdzesi siwo le wò dɔwɔwɔ me tsonu me fia gɔme.
PTH ƒe agbɔsɔsɔ kple nusiwo gbɔ wòtso Nusiwo ate ŋu ana PTH ƒe agbɔsɔsɔ nadzi ɖe edzi (Hyperparathyroidism): Nusiwo ate ŋu ana PTH ƒe agbɔsɔsɔ naɖiɖi (Hypoparathyroidism):
Ðe wòahiã be mawɔ dodokpɔ bubuwoa?
Ẽ, wò ɖɔkta ate ŋu aɖo aɖaŋu be nàgawɔ dodokpɔ bubuwo le wò PTH kple calcium ƒe agbɔsɔsɔ nu.
- Le kpɔɖeŋu me, ne wò PTH ƒe agbɔsɔsɔ sɔ gbɔ gake wò calcium ƒe agbɔsɔsɔ le sue la, ate ŋu afia be wò parathyroid lãkusiwo le dɔ wɔm nyuie. Emegbe wò ɖɔkta alé ŋku ɖe wò vitamin D, phosphorus, kple magnesium ƒe agbɔsɔsɔ ŋu akpɔe ɖa be wole ŋusẽ kpɔm ɖe wò calcium ƒe agbɔsɔsɔ dzi hã.
- Le go bubu me la, ne wò calcium ƒe agbɔsɔsɔ sɔ gbɔ eye wò PTH ƒe agbɔsɔsɔ sɔ gbɔ wu alesi wòle be wòanɔ la, ke àte ŋu axɔ hyperparathyroidism. Ne edzɔ alea la, wò ɖɔkta awɔ X-ray alo nɔnɔmetata bubu dodokpɔ aɖe atsɔ ado wò parathyroid glandwo kpɔ.
Ne lãkusiawo vuvu alo dɔdzẽ le wo ŋu la, woate ŋu awɔ dɔ na wo be woaɖe lãkusiawo ɖa. Gake ne wò dɔlélea mesẽ o eye dzesi aɖeke mele ŋuwò abe ayiku me kuxiwo alo ƒu siwo gbɔdzɔ ene o la, wò ɖɔkta adi be yealé ŋku ɖe wò calcium kple PTH ƒe agbɔsɔsɔ ŋu edziedzi. Woate ŋu aŋlɔ atike aɖe abe Cinacalcet (Sensipar) ene hã na wò. Le nɔnɔme mawo me la, ɖewohĩ mahiã be woawɔ dɔ na ame o.
Gbedasi si Wotsɔ Yi Aƒeme
- PTH ʋudodokpɔ nye dodokpɔ vevi aɖe si wowɔna tsɔ dia nusi gbɔ calcium ƒe agbɔsɔsɔ si mesɔ o tsona le wò ʋu me.
- Esia nye ʋudodokpɔ si wowɔna edziedzi si me afɔku boo aɖeke mele o, eyata mehiã be nàvɔ̃ o.
- Wò ɖɔkta anɔ te ɖe wò dzesiwo, calcium ƒe agbɔsɔsɔ, kple PTH ƒe agbɔsɔsɔ dzi atso nya me le nusi nàwɔ azɔ ŋu.
- Ne èxɔ wò dodokpɔa me tsonu la, kpɔ egbɔ be yeƒo nu kple yeƒe ɖɔkta be yease wo gɔme bliboe.
- Mègadzudzɔ wò atikewo nono alo atrɔ agbɔsɔsɔme si woazã wò ɖɔkta ƒe aɖaŋuɖoɖo manɔmee gbeɖe o.
Parathyroid hormone, PTH dodokpɔ, calcium, ʋudodokpɔ, hypercalcemia, hypocalcemia, ayikudɔ
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