Ðe nèsena le ɖokuiwò me zi geɖe be ɖeɖi te ye ŋu eye yeƒe lãme gbɔdzɔa? Ðe wòsesẽna na wò be nàgbɔ ya ne èzɔ kabakaba vie alo nèlia atrakpuiwoa? Ðewohĩ èsena le ɖokuiwò me hã be yeƒe ŋutigbalẽ le ɣie wu tsã. Esiawo ate ŋu anye ʋu ƒe anyimanɔmanɔ ƒe dzesiwo le ŋutilãa me, si nye nusi míeyɔna le atikewɔwɔ me be ʋusɔgbɔdɔ. Gake ɣeaɖewoɣi la, nusi gbɔ ʋusɔgbɔdɔ sia tsona ate ŋu anye dɔléle si sesẽ wu eye mebɔ o wu alesi míesusui. Egbea míele nu ƒom tso dɔléle mawo dometɔ ɖeka si mebɔ o, gake wòle vevie ŋutɔ si do ƒome kple ʋu ŋu. Emae nye Pure Red Cell Aplasia, si míeyɔna kpuie be PRCA.
Kpuie ko la, nukae nye PRCA sia?
Bu ƒumeŋuɖui si le míaƒe ŋutilã me be enye ʋuwɔƒe. Dɔwɔƒe sia wɔa lãmenugbagbevi ƒomevi etɔ̃ siwo míaƒe ŋutilã hiã: ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo. Dɔ vevitɔ si ʋumenugbagbevi dzĩwo wɔnae nye be woatsɔ ɔksidzin si gena ɖe míaƒe lãkusiwo me ne míele gbɔgbɔm la ayi na lãmenugbagbevi bubu siwo katã le míaƒe ŋutilã me. Ele abe agbatsɔʋuwo ƒe dɔwɔƒe si tsɔa ɔksidzin yinae ene.
Fifia le PRCA gome la, ʋuwɔƒe, si nye ƒumeŋuɖui, ɖea ʋumenugbagbevi dzĩwo ɖeɖeko dzi kpɔtɔna ŋutɔ alo dzudzɔa wo wɔwɔ keŋkeŋ . Lãmenugbagbevi ƒomevi bubuwo (ʋumenugbagbevi ɣiwo kple ʋumenugbagbevi dzĩwo) ƒe wɔwɔ dzɔna le mɔ si sɔ nu. Eyata ne ʋumenugbagbevi dzĩ siwo tsɔa ɔksidzin yia ŋutilãa me dzi ɖe kpɔtɔ la, míaƒe ŋutilã ƒe ŋutinuwo mexɔa ɔksidzin si wohiã o. Ʋusɔgbɔdɔ sesẽ si dona tso esia me ye nye PRCA ƒe kuxi vevitɔ.
Dzesi kawoe ate ŋu akpɔ amesi ŋu PRCA le?
PRCA hea dzesi siwo nye ʋusɔgbɔdɔ sesẽ vɛ, gake woate ŋu asẽ wu ʋusɔgbɔdɔ si sɔ. Ele vevie be nànya dzesi siawo.
| Dzesi si dzena | Numeɖeɖe bɔbɔe aɖe |
|---|---|
| Ɖeɖiteameŋu | Sese le ɖokuiwò me be agbe mele ye ŋu o eye ɖeɖi tea ye ŋu ɣesiaɣi, aleke kee nèɖadɔ alɔ̃ o. |
| Yagbɔgbɔ sesẽ (Dyspnea) . | Gbɔgbɔtsixetsixe ƒe seselelãme le dɔ sue aɖe wɔwɔ alo azɔlizɔzɔ kpui aɖe megbe gɔ̃ hã. |
| Taɖuame | Taɖuame ƒe seselelãme, vevietɔ ne èfɔ tso anyinɔƒe. |
| Ŋutilã si ƒe ŋutigbalẽ le ɣie | Ŋutilã, nuyiwo, kple ɖa te va nɔa ɣie wu alesi wònɔna ɖaa. |
| Taɖuame enuenu | Oxygen si ahɔhɔ̃a hiã dzi ɖeɖe kpɔtɔ gbɔe taɖuame enuenu tsona. |
| Towo ƒe ɖiɖi sese (Pulsatile tinnitus) . | Wosea kpẽ ƒe ɖiɖi le towo me le ɖekawɔwɔ me kple dzi ƒe tsotso ƒe tsɔtsɔme. |
| Akɔtave (Angina) . | Akɔtave le esi oxygen ƒe anyimanɔmanɔ na dzitodzito me lãmekawo ta. |
Nu vevitɔe nye be, ne dzesi siawo dometɔ ɖeka alo esi wu nenema le ŋuwò la, mègatsi dzodzodzoe eye nàsusu be PRCA ye o. Woate ŋu akpɔ esiawo le ʋusɔgbɔdɔ si sɔ hã me. Gake ne dzesi siawo gakpɔtɔ li la, anyo godoo be nàyi ɖɔkta gbɔ ahaɖo aɖaŋu na wò.
Nukatae nɔnɔme sia si woyɔna be PRCA la dzɔna?
PRCA menye dɔléle ɖeka kolia o. Nu geɖe li siwo ate ŋu ahe esia vɛ. Ɣeaɖewoɣi la, ate ŋu anye atikewɔwɔ me nɔnɔme bubu aɖe hã ƒe nugbegblẽ le ame ŋu.
1. Dɔlélenutsiŋutete ƒe kuxiwo (Autoimmune Diseases) .
Esiae nye nu vevitɔ si gbɔ PRCA tsona. Kpuie ko la, míaƒe ŋutilã ƒe ametakpɔnu, si nye dɔlélenutsiŋutete, dzea lãmenugbagbevi siwo le mía ŋutɔwo ƒe ƒumeŋuɖui siwo wɔa ʋumenugbagbevi dzĩwo la dzi dzedze gɔme vodadatɔe. Nɔnɔme mawo ƒe kpɔɖeŋu aɖewoe nye:
- Lupus dɔléle (Systemic Lupus Erythematosus) ƒe dɔléle .
- Lãmetsiŋusẽdɔléle
- Dɔgbo ƒe Dɔléle si Naa Dɔdzẽ
2. Kansa
Kansa ƒomevi aɖewo hã ate ŋu ahe PRCA vɛ.
- Kansa siwo do ƒome kple ʋu: Chronic Lymphocytic Leukemia (CLL) kple Large Granular Lymphocytic Leukemia (LGL) ye nye ʋumenugbagbeviɣidɔ ƒomevi eve siwo do ƒome kple esia koŋ.
- Dɔdzẽ: Thymoma, si nye thymus gland ƒe kansa, ye nye kansa ƒe dɔdzẽ vevitɔ si do ƒome kple PRCA.
3. Dɔlékui kple dɔlékuiwo ƒe dɔlélewo
Dɔlékui aɖewo hã ate ŋu ahe PRCA vɛ, hena ɣeyiɣi aɖe alo tegbee.
- Dɔlékuiwo: Parvovirus B19 ye nye esi wonya nyuie wu le esiawo dome. Dɔlékui sia dzea lãmenugbagbevi siwo le ƒumeŋuɖui me siwo le ʋumenugbagbevi dzĩwo zu ge la dzi tẽ. HIV, Epstein-Barr dɔlékui, kple aklãdɔlékuiwo hã ate ŋu ahee vɛ.
- Dɔlékuiwo: Nɔnɔmewo abe Ƒuƒoƒo C Streptococcus, Yɔmekpe, kple Dɔlékuiwo ƒe Dɔlékuiwutikewo hã ate ŋu ahe esia vɛ.
4. Atike aɖewo
PRCA ate ŋu adzɔ hã abe atike aɖewo ƒe nugbegblẽ le ame ŋu ene. Le kpɔɖeŋu me, Erythrocyte-Stimulating Agents (ESAs), siwo nye atike siwo wonaa ayikudɔlélawo be woadzi ʋumenugbagbevi dzĩwo ƒe wɔwɔ ɖe edzi la ate ŋu ahe nɔnɔme sia vɛ ɣeaɖewoɣi.
5. Fufɔfɔ
Ƒã ŋutɔ la, nyɔnu aɖewo ate ŋu axɔ PRCA le fufɔɣi. Dzɔgbenyuietɔe la, zi geɖe la, nɔnɔmea nu tsona le eɖokui si le vidzĩa dzidzi vɔ megbe.
6. Domenyiŋusẽfianu ƒe nɔnɔme siwo nɔa anyi le vidzidzi me
Diamond-Blackfan Anemia nye ʋusɔgbɔdɔ si mebɔ o si wodzina. Zi geɖe la, wokpɔnɛ le ɖevime. Dɔnɔ siawo ate ŋu axɔ PRCA hã.
Aleke ɖɔktawo wɔa anya dɔléle sia pɛpɛpɛ?
Ne èyi ɖɔkta gbɔ kple dzesi siwo míeyɔ va yi la, ado wò kpɔ eye ne esusu be dɔléle sia le ŋuwò la, aɖo wò ɖe dodokpɔ geɖe wɔwɔ me.
| Dodokpɔ | Nukae nèkpɔ le afisia? |
|---|---|
| Ʋu Xexlẽme Blibo (CBC) . | Woléa ŋku ɖe ʋua ŋu be woakpɔe ɖa be ʋumenugbagbevi dzĩwo ƒe xexlẽme le sue ŋutɔ hã, eye ne ʋumenugbagbevi ɣiwo kple ʋumenugbagbevi dzĩwo ƒe xexlẽme sɔ hã. |
| Reticulocyte ƒe Xexlẽme | Esia fia ʋumenugbagbevi dzĩ siwo wowɔ yeyee, siwo metsi o. Le PRCA la, xexlẽme sia le sue ŋutɔ. Esia fia be womele lãmenugbagbevi dzĩ yeye aɖeke wɔm o. |
| Ʋu ƒe Ʋuʋu le Gome | Woɖea ʋu aɖe hedoa ekpɔ le nusuekpɔmɔ̃ me be woatsɔ alé ŋku ɖe ʋumenugbagbevi dzĩawo ƒe nɔnɔme kple woƒe nɔnɔme ŋu. |
| Ƒumeŋuɖui ƒe Aspiration/Biopsy | Esiae nye dodokpɔ vevitɔ si woatsɔ aɖo kpe dɔlélea dzi . Woɖea ƒumeŋuɖui sue aɖe ŋutɔ tso teƒe aɖe abe akɔta ene le atike si wua alɔ̃dɔdɔ vɔ megbe. Le PRCA gome la, womekpɔa lãmenugbagbevi siwo wɔa ʋumenugbagbevi dzĩwo le eme o. |
| Dodokpɔ bubuwo | Be woanya nusi gbɔ dɔlélea tso la, woate ŋu awɔ dodokpɔwo abe Parvovirus B19 dɔlékui dodokpɔ kple CT scan (be woatsɔ akpɔe ɖa be dɔdzẽ abe thymoma ene hã le eme). |
Nukawoe nye atike siwo wozãna na PRCA?
PRCA dada nɔ te ɖe nusi gbɔ dɔlélea tso dzi. Esia fia be menye amesiamee wowɔa nu ɖe ame ŋu ɖekae o. Ðɔktaa asrɔ̃ nu tso wò nɔnɔmea ŋu nyuie eye wòatia atike si sɔ wu.
- Dɔlélenutsiŋutete ƒe dɔlékuiwutikewo: Ne dɔlélenutsiŋutete ƒe kuxie gbɔe dɔlélea tso la, atike siawo wɔa dɔ tsɔ ɖua dɔlélenutsiŋutete si wɔa dɔ fũu akpa dzi. Wozãa corticosteroids abe Prednisone kple Cyclosporine ene zi geɖe na esia.
- Ʋudodo: Ne ʋusɔgbɔdɔa nu sẽ ŋutɔ la, wodoa ʋu ɖe gota be ʋua ƒe agbɔsɔsɔme nagaɖo eŋu kaba. Gake ʋudodo atraɖii ate ŋu ana iron ƒe agbɔsɔsɔ si le ŋutilãa me nadzi ɖe edzi madzemadzee. Ne edzɔ alea la, ahiã be woawɔ atike vovovowo (chelation therapy) atsɔ aɖe iron si sɔ gbɔ ɖe eme la ɖa.
- Amekoko: Ne nusi gbɔ dɔlélea tsoe nye thymoma la, atikewɔwɔe nye amekoko be woaɖe lãkusia ɖa (Thymectomy).
- Dɔlékuiwutikewo ƒe Dɔdamɔnu: Ne parvovirus B19 dɔlékui aɖe gbɔe PRCA tso la, atikewɔwɔ sia wɔa avu kple dɔlékuia eye wòxea mɔ nɛ be megagblẽa nu le ʋumenugbagbevi dzĩwo ŋu o.
- Lãmenugbagbeviwo Dodo Ðe Ame Ŋu:Le amesiwo ŋu wodzia dɔlélewo abe Diamond-Blackfan Anemia ene le gome la, atikewɔwɔ bia be woado lãmenugbagbevi siwo le lãmesẽ me ɖe ƒumeŋuɖui siwo ŋu dɔléle le teƒe.
Ðe atikewɔwɔa ƒe nugbegblẽ aɖewo lia?
Ẽ, abe atikewɔwɔ ɖesiaɖe ene la, ate ŋu agblẽ nu le eŋu. Gake mehiã be míatsi dzi ɖe wo ŋu o. Wò ɖɔkta ana nànya nu tso nusiawo katã ŋu hafi adze atikewɔwɔ gɔme. Aɖo aɖaŋu siwo hiã hã wò be nàtsɔ akpɔ eƒe nugbegblẽ le ame ŋu gbɔ.
Le kpɔɖeŋu me, dɔlélenutsiŋutete ƒe atikewo ate ŋu ana dɔlékuiwo xɔxɔ ƒe afɔkua nadzi ɖe edzi, wò ʋu ƒe sisi nadzi ɖe edzi, eye wò kpekpeme nadzi ɖe edzi. Ʋudodo ate ŋu ana asrã kple nulɔdɔ nadze ame dzi. Eyata ele vevie ŋutɔ be nàlé ŋku ɖe tɔtrɔ siwo vaa wò ŋutilã me le atikewɔwɔ me ŋu nyuie.
Nukae wòle be nànya ne èle PRCA gbɔ?
PRCA ate ŋu anye dɔléle si nɔa anyi didi ɣeaɖewoɣi. Esia fia be le atikewɔwɔ vɔ megbe gɔ̃ hã la, dɔlélea ate ŋu agadzɔ ɣeaɖewoɣi. Eyata ele vevie be woanɔ atikewɔlawo ƒe dzikpɔkpɔ te.
- Beléle na Dɔlélea: Ðewohĩ ahiã be ame aɖewo nayi edzi anɔ dɔlélenutsiŋutete ƒe atikewo nom le agbɔsɔsɔ sue aɖe me be dɔlélea nagatrɔ ava o.
- Dzɔdzɔmenuwo Dzi Kpɔkpɔ Madzudzɔmadzudzɔe: Ele vevie be nàyi ɖɔkta gbɔ edziedzi eye woado wò ʋu kpɔ. Esia ate ŋu akpe ɖe ŋuwò nàde dzesii kaba nenye be dɔlélea agava loo alo ahe kuxi bubuwo vɛ.
- Agbenɔnɔ si me lãmesẽ le:
- Nuɖuɖu si me nunyiame le: Ele vevie be woaɖu nuɖuɖu si da sɔ, si me nuɖuɖu siwo me iron sɔ gbɔ ɖo (aŋanyi, lã, peas, lentils) hã le. Bia wò ɖɔkta tso nuɖuɖu si sɔ na wò ŋu.
- No tsi si sɔ: Mexe mɔ na tsi ƒe vɔvɔ le ŋutilãa me o.
- Takpɔ ɖokuiwò tso dɔlékuiwo me: Klɔ asi enuenu. Kpɔ nyuie le teƒe siwo amewo sɔ gbɔ ɖo. Na atikewɔmɔnu siwo hiã.
- Kamedede: De kame le ɖoɖo si nu wò ŋutilã ate ŋu ado dzi le nu. Azɔ hã, bia wò ɖɔkta tso esia ŋu.
Ne èse PRCA ŋu nya la, vɔvɔ̃ ate ŋu anɔ ŋuwò. Ema sɔ. Gake ɖo ŋku edzi be enye dɔléle si woate ŋu ada. Nu vevitɔe nye be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo kaba eye nàwɔ ɖe atikewɔwɔa dzi pɛpɛpɛ, eye màŋe aɖaba aƒu dzesiawo dzi o.
Gbedasi si Wotsɔ Yi Aƒeme
- PRCA nye ʋumenugbagbeviɣidɔ si mebɔ o si nana ƒumeŋuɖui mete ŋu wɔa ʋumenugbagbevi dzĩwo o.
- Eƒe dzesi vevitɔwoe nye ɖeɖiteameŋu ɣesiaɣi, eƒe ŋutigbalẽ biã, kple gbɔgbɔ sesẽ.
- Esia ate ŋu atso dɔlélenutsiŋutete ƒe kuxiwo, kansa, dɔlékuiwo, kple atike aɖewo gbɔ.
- Dodokpɔ vevitɔ si woatsɔ aɖo kpe dɔlélea dzie nye ƒumeŋuɖui ŋuti numekuku.
- Atikewɔwɔ ƒe mɔnuwo toa vovo le nusi gbɔ dɔlélea tso nu, eye atikewɔwɔ ate ŋu aɖu dzesiawo dzi.
- Esi wònye be esia ate ŋu agadzɔ ɣeaɖewoɣi ta la, atikewɔwɔ ƒe ŋkuléle ɖe ame ŋu ɣeyiɣi didi kple dodokpɔ edziedzi le vevie ŋutɔ.
- Ne dzesi siwo ɖi ʋusɔgbɔdɔ ƒe dzesiwo yi edzi le fu ɖem na wò la, mègatsi dzodzodzoe eye nàkpɔ wò ɖɔkta enumake o.
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