Has your doctor prescribed you a medicine called Repaglinide for Type 2 Diabetes? Or is someone in your family using this medicine? Then it is very important to be fully informed about this medicine. Because, like any medicine, to get the most out of it, it is essential to know how to use it, what to be careful about, and the side effects . We will talk about all of that in this article.
What is Repaglinide?
Simply put, Repaglinide is a medication used to treat type 2 diabetes . It comes in the form of a pill.
Now let's see how this works. Our body has an organ called the pancreas . This produces a hormone called insulin . Insulin controls the level of sugar (glucose) in our blood and helps the cells absorb sugar. In a person with type 2 diabetes , the body may produce less insulin, or the insulin that is produced may not work properly. Repaglinide tablets stimulate the pancreas and help it produce more insulin. Then the sugar level in the blood is controlled.
But remember one thing. You cannot control diabetes by taking this medicine alone. You must also follow a proper diet and exercise daily .
Things you need to tell your doctor before taking medicine
Before giving you Repaglinide, your doctor will ask you a few questions. At that time, it is very important to tell them if you have any of the following conditions:
- If you have an emergency condition called diabetic ketoacidosis, which is caused by diabetes.
- If you have kidney disease or liver disease.
- If you have a severe infection or injury.
- If you have an allergic reaction to repaglinide or any other medicine, food, or dye.
- If you are pregnant, trying to get pregnant, or breastfeeding, be sure to tell your doctor about this.
How to use Repaglinide tablets correctly?
To get the most out of this medicine, it is very important to use it correctly.
- Swallow this pill with a glass of water.
- The most important thing is to take this pill before a meal. Usually, it is said to be taken between 15 and 30 minutes before a meal. Do not take it more than 30 minutes before.
- Imagine you missed breakfast. Then you should also skip the pill for that time. If you don't eat, don't take the pill.
- Never take more than the dose prescribed by your doctor, or take two doses at once.
- If you are over 65, you may be prescribed a lower dose. Talk to your doctor about this.
What if I take too much medicine? (Overdose)
If you think you have taken too much medicine by mistake, don't panic. Immediately call the National Poisons Information Centre at the Colombo National Hospital . Or go to the Emergency Treatment Unit (ETU) of the nearest hospital.
What if I miss a dose of medicine?
If you miss a dose that is supposed to be taken before a meal, skip that meal. Take the next dose as scheduled with your next meal. Do not take two pills at once to make up for a missed dose.
Other medications that may interact with this medicine
This is a very important part. If you are taking Repaglinide, you should tell your doctor about all other medications you are taking (including vitamins and herbal remedies), as some medications may interact with Repaglinide.
| Drug type | Notes and examples |
|---|---|
| Medicines that should never be taken with this medicine | |
| Gemfibrozil | This is a medicine that lowers cholesterol. If taken with Repaglinide, it can cause severe low blood sugar. |
| Other drugs that may interact with Repaglinide | |
| Various medications | For example: Clopidogrel, Cyclosporine, Rifampin, Simvastatin, Trimethoprim, antifungals (Itraconazole, Ketoconazole). Some of these can increase or decrease the effect of Repaglinide. |
| Medications that can affect blood sugar levels | |
| Many types of drugs | For example: Alcohol, aspirin, steroids, some antibiotics, high blood pressure medications, birth control pills, and some cough/cold syrups. These can cause changes in blood sugar levels. |
| Medications that can mask the warning signs of hypoglycemia | |
| Beta-blockers | For example: Metoprolol, Propranolol. While taking these medications, you may not notice the symptoms (such as shaking, sweating) of low blood sugar. Therefore, it is important to check your blood sugar levels regularly. |
Things to be careful about when taking medicine
- Regular check-ups: See your doctor and check your condition regularly.
- HbA1c test: You should also be aware of the blood test called HbA1c (HbA1c). This measures how well your diabetes has been controlled over the past 2-3 months.
- Measuring blood sugar levels: Learn how to measure your blood sugar levels at home. Know the symptoms of hyperglycemia and hypoglycemia, and how to manage them.
- Be prepared for emergencies: If you experience symptoms of hypoglycemia, always carry some sugar (e.g., sugar cubes, glucose tablets) with you. If you become severely hypoglycemic and lose consciousness, do not put anything in your mouth as it could cause choking. Tell your family to seek immediate medical attention.
- Medical ID: Wearing a card or bracelet that states that you have diabetes and the medications you take can be very useful in an emergency.
What side effects can be seen?
Like all medicines, Repaglinide can cause side effects, although not everybody gets them.
| Side effect | Description |
|---|---|
| Serious side effects that should be reported to the doctor immediately | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Low blood sugar (Hypoglycemia) | Tremors, extreme anxiety, sweating, coldness, confusion, dizziness, rapid heartbeat. |
| Side effects that are usually not serious, but should be reported to the doctor if they persist | |
| Other disorders | Back pain, indigestion/diarrhea, headache, joint pain, nausea, runny nose. |
Take-Home Message
- Repaglinide is a medication used to treat type 2 diabetes. Along with this , a proper diet and exercise are essential.
- Always take this pill 15-30 minutes before a meal . If you miss a meal, skip the dose.
- Tell your doctor about all other medications you are taking (especially Gemfibrozil).
- Be aware of the symptoms of low blood sugar (hypoglycemia). Always keep something like a sugar cube nearby for use in an emergency.
- If you accidentally take too much medicine, call the National Poisons Information Centre immediately or go to the nearest hospital emergency department (ETU).
- This medicine is for you only. Never share it with others.
Repaglinide, Diabetes, Type 2 Diabetes, Sugar Level, Insulin, Hypoglycemia, Prandin


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