He aha ka Glycogen? E kamaʻilio kākou e pili ana i ka mālama ʻana i ka ikehu o ko kākou kino ma nā ʻōlelo maʻalahi!

Ua noʻonoʻo paha ʻoe pehea e mālama ai ko mākou kino i ka ikehu a mākou e loaʻa ai mai ka meaʻai a mākou e ʻai ai no ka hoʻohana ʻana ma hope? ʻO ia kahi e komo mai ai kahi mea kūikawā i kapa ʻia ʻo glycogen . Ua like ia me kahi panakō mana e hoʻopiha mau ana i kā mākou kelepona.

He aha ka glycogen?

I ka ʻōlelo maʻalahi, ʻo ka glycogen kahi ʻano kō i kapa ʻia he glucose i mālama ʻia i loko o ko kākou kino. Hana ʻia ia me nā molekole glucose he nui i hoʻopaʻa ʻia.

I kēia manawa, ke nīnau nei paha ʻoe he aha ka glucose. ʻO ka glucose ka wahie nui e hāʻawi ai i ka ikehu i ko mākou kino. Loaʻa iā mākou kēia glucose mai kekahi o nā meaʻai a mākou e ʻai ai, ʻoiai nā mea i loaʻa nā kalapona. Inā ʻaʻole pono koke ka glucose mai nā meaʻai a mākou e ʻai ai no ka ikehu, mālama ko mākou kino iā ia ma ke ʻano he glycogen i loko o ke akepaʻa a me nā ʻiʻo , no ka hoʻohana ʻana ma hope.

ʻO ke kaʻina hana e hana ai ko kākou kino i ka glycogen mai ka glucose ua kapa ʻia ʻo Glycogenesis . Eia kekahi, ʻo ke kaʻina hana e hoʻihoʻi ʻia ai kēia glycogen i glucose i ka wā e pono ai a hoʻohana ʻia no ka ikehu ua kapa ʻia ʻo Glycogenolysis . Kōkua ʻia kēia mau kaʻina hana ʻelua e nā ʻano enzyme like ʻole. ʻO nā enzymes nā ʻano protein kūikawā i loaʻa i loko o kā mākou mau cell. Hana lākou ma ke ʻano he catalysts a kōkua i nā kaʻina hana like ʻole i loko o ke kino e holo mālie. He mau tausani o ia mau enzymes ma loko o ko kākou kino, a hana kēlā me kēia o lākou i kahi hana koʻikoʻi.

He aha ka ʻokoʻa ma waena o Glycogen, Glucose a me Glucagon?

I kēia manawa, e nānā kākou i ka ʻokoʻa ma waena o kēia mau huaʻōlelo ʻekolu: Glycogen, Glucose, a me Glucagon. Pili nā mea ʻekolu i ke ʻano o ka hoʻohana ʻana o ko kākou kino i nā kalapona no ka ikehu, akā he ʻokoʻa ka hana a kēlā me kēia.

KulukoseʻO ia ke ʻano kō a mākou e loaʻa ai mai nā meaʻai a mākou e ʻai ai, ʻoiai hoʻi nā kalapona. ʻO ke ʻano nui o ke kō i loko o ko mākou koko, ʻo ia ka glucose koko, a i ʻole ka mea a mākou e kapa nei ʻo ' ke kō koko'. Hāʻawi kēia kō i ka ikehu i ko mākou kino, a hānai pū ia i ko mākou mau ʻōpū, nā ʻiʻo, a me ka ʻōnaehana nerve. He mea nui loa ka glucose no ka mea ʻo ia ke kumu nui o ka ikehu no ko mākou lolo. ʻO ka ʻoiaʻiʻo, pono mau ko mākou lolo i ka glucose, ʻo ia ke kumu i ʻōlelo ʻia ai e ʻai ka pākeke ma ka liʻiliʻi he 130 grams o nā kalapona i kēlā me kēia lā.

I kēia manawa, ua ʻike mākou i ka wā e pono ʻole ai ko mākou kino i ka glucose, ua mālama ʻia ia i loko o ko mākou ake a me nā ʻiʻo e like me ka glycogen .

He hormone ka Glucagon i hana ʻia e ko kākou pancreas. Kōkua ia i ka hoʻololi ʻana i ka glycogen i mālama ʻia i glucose a hoʻokuʻu iā ia i loko o ke koko. A laila hiki i ke kino ke hoʻohana i kēlā glucose no ka ikehu. ʻO Glucagon a me ka insulin nā hormones ʻelua e kaohi nui i nā pae glucose koko i loko o ko kākou kino.

He kalapona anei ka glycogen?

No laila, he kalapona anei ka glycogen? ʻĀ, hana ʻia ka glycogen mai nā kalapona, ʻo ia hoʻi, mai nā meaʻai starchy a mākou e ʻai ai. Eia naʻe, ʻaʻole he kalapona ka glycogen. Ke ʻai mākou i nā meaʻai i loaʻa nā kalapona, wāwahi ko mākou kino iā lākou a hoʻolilo iā lākou i glucose e hoʻohana ai no ka ikehu. ʻO Glycogen ke ala e mālama ʻia ai ka glucose. Hana ʻia ia me kahi puʻu o nā molekala glucose i hoʻopili ʻia.

Ma hea e mālama ʻia ai ka glycogen?

ʻAe, ma hea kahi i mālama ʻia ai kēia glycogen i loko o ko kākou kino? Mālama nui ʻia ʻo Glycogen i loko o ko kākouLoaʻa ia i loko o ke akepaʻa a me nā ʻiʻo iwi . ʻO nā ʻiʻo nā ʻiʻo i hoʻopili ʻia i ko kākou mau iwi a me nā tendon. Eia kekahi, he liʻiliʻi loa ka nui i mālama ʻia i loko o ko kākou lolo.

ʻOiai ke mālama nei ko kākou akepaʻa i ka pakeneka kiʻekiʻe o ka glycogen ma mua o ko kākou mau ʻiʻo, ʻoi aku ka nui o ko kākou nui o nā ʻiʻo ma mua o ko kākou akepaʻa, no laila ʻekolu hapahā wale nō o ka glycogen holoʻokoʻa i loko o ke kino i loko o ko kākou mau ʻiʻo.

Ke hoʻoikaika kino mākou, ʻoiai no ka manawa lōʻihi, hiki ke emi nui ka nui o ka glycogen i loko o nā ʻiʻo ikaika. Hoʻololi ka nui o ka glycogen i loko o nā ʻiʻo ate i ka lā a pau. ʻO kēia ma muli o kekahi mau kumu:

• ʻO ka nui o nā kalapona a mākou e ʻai ai.
• ʻO ka manawa a mākou e mālama ai ma waena o nā meaʻai.
• Ka ikaika a me ka lōʻihi o ka hana kino a mākou i hana ai i kēia mau lā iho nei.

E noʻonoʻo, inā ʻaʻole ʻoe e ʻai no 12 a 24 mau hola (hoʻokē ʻai), ua hoʻopau ʻia ka glycogen āpau i loko o ke ake.

He aha ka lawelawe a ka glycogen i ko mākou kino?

I kēia manawa, e nānā kākou i ka lawelawe a kēia glycogen e hāʻawi ai i ko kākou kino. Ma muli o kahi i mālama ʻia ai - inā paha ma ke akepaʻa a i ʻole ma nā ʻiʻo - ʻokoʻa iki hoʻi kāna hana.

Ka Hana o nā Hale Kūʻai Glycogen o ke Ate

Hoʻohana ko mākou kino i ka glycogen, ʻo ia hoʻi i loko o ke akepaʻa , e kōkua i ka kaohi ʻana i nā pae glucose koko.

ʻO ka maʻamau, hoʻomalu pono ko mākou kino i ko mākou pae kō koko me nā hormones i kapa ʻia ʻo glucagon a me ka insulin. Inā haʻahaʻa loa ko mākou pae kō koko, ʻo ia hoʻi ka hypoglycemia , hoʻokuʻu ko mākou pancreas i ka glucagon hou aku. ʻO kekahi o nā mea a glucagon e hana ai, ʻo ia ka hoʻololi ʻana i ka glycogen i loko o ke akepaʻa i glucose a hoʻokuʻu iā ia i loko o ke koko. E hoʻomanaʻo paha ʻoe ua kapa mākou i kēia kaʻina hana ʻo glycogenolysis. Ke hoʻokuʻu ʻia ka glucose i loko o ke koko, hiki i nā ʻāpana ma ke kino ke hoʻohana iā ia no ka ikehu.

Kōkua pū nā waihona glycogen i loko o ke akepaʻa i ka hana ʻana o nā ʻiʻo a me ka hoʻoikaika kino i kekahi ʻano. Ke hoʻomaka ʻoe e hoʻoikaika kino, hoʻohana kou mau ʻiʻo hana i ka glucose no ka ikehu, no laila hoʻomaka ke akepaʻa e wāwahi i ka glycogen e mālama i nā pae kō koko. Eia nō naʻe, hoʻohana nui kou mau ʻiʻo i kā lākou mau waihona glycogen ponoʻī.

Hana o nā Hale Kūʻai Glycogen Muscle

ʻO Glycogen i loko o nā ʻiʻo ka mea nui e hana ma ke ʻano he kumu o ka wahie metabolic no ko mākou mau ʻiʻo.

I mea e neʻe ai kākou, pono ko kākou mau ʻiʻo i ka nui o ka ikehu. E noʻonoʻo, inā e lawe ko kākou mau ʻiʻo i ka glucose mai ke koko e loaʻa ai kēia ikehu, e pau koke ana ka glucose i loko o ke kino.

ʻO ia ke kumu e mālama ai ko mākou kino i ʻekolu hapahā o nā glycogen āpau i loko o kēlā me kēia ʻiʻo iwi. ʻAe kēia i nā ʻiʻo e hoʻomau i ka loaʻa ʻana o ka ikehu me ka ʻole o ka hoʻopilikia nui ʻana i nā pae kō koko, ʻoiai i ka wā hoʻoikaika kino.

ʻO ka wikiwiki o ka hoʻopau ʻia ʻana o ka glycogen i loko o ko kākou mau ʻiʻo e pili nui ana i ka ikaika o ka hana kino. I ka piʻi ʻana o ka ikaika o ka hoʻoikaika kino, piʻi pū ka wikiwiki o ka hoʻopau ʻia ʻana o ka glycogen i loko o nā ʻiʻo. No laila, i ka wā o nā hana ikaika, e like me ka holo wikiwiki ʻana , hiki ke hoʻopau koke ʻia nā waihona glycogen i loko o nā ʻiʻo hana, ʻoiai inā he pōkole ka lōʻihi o ka hana.

Ke ʻai mākou i nā kalapona lawa, hoʻopiha hou ko mākou mau ʻiʻo me ka glycogen.

He aha ka maʻi mālama Glycogen (GSD)?

I kekahi manawa, hiki ke kū mai nā pilikia me kēia glycogen. ʻO kekahi o ia ʻano maʻi ka maʻi mālama glycogen, a i ʻole GSD no ka pōkole.

He maʻi laha ʻole ka GSD, he maʻi hoʻoilina ia.ʻO kēia ka wā e hānau ʻia ai ke kanaka me ka ʻole o kekahi mau enzymes e pono ai e hana a/a i ʻole e wāwahi i ka glycogen. No ka mea, hoʻohana ko mākou kino i nā enzymes like ʻole e hana i ka glycogen, nui nā ʻano GSD like ʻole. Hiki i ka GSD ke hōʻino pinepine i ke akepaʻa a me ka nāwaliwali o nā ʻiʻo . I nā ʻano GSD he nui, ʻike mua ʻia nā hōʻailona i ka wā kamaliʻi a i ʻole ka wā kamaliʻi.

He aha nā hoʻokolohua e hiki ke hoʻohana ʻia no ka nānā ʻana i nā pae glycogen?

No laila, aia kekahi mau hoʻokolohua kūikawā e nānā i nā pae glycogen i loko o ko kākou kino? ʻOiaʻiʻo, ʻaʻohe hoʻokolohua kūikawā e ana wale i nā pae glycogen. Eia kekahi, loli mau ko kākou mau pae glycogen ma muli o ka nui o ka hana a kākou e hana ai a me ka nui o nā kalapona a kākou e ʻai ai i kēlā me kēia lā.

Akā, inā loaʻa iā ʻoe nā hōʻailona, ​​hoʻohana nā kauka i nā hoʻokolohua ʻē aʻe e ʻike ai inā he pilikia kou me ke ʻano o ka hana ʻana a me ka wāwahi ʻana o kou kino i ka glycogen, i kapa ʻia ʻo ka maʻi mālama glycogen (GSD). ʻO kēia mau hoʻokolohua:

• Nā hoʻāʻo koko: Hiki i nā mea e like me ka panela hana akepaʻa a me ka panela hana puʻupaʻa ke kōkua iā ʻoe e ʻike i ka maikaʻi o ka hana ʻana o kēia mau ʻōkana. Hiki i kahi hoʻāʻo pae glucose koko ke kōkua iā ʻoe e ʻike i ka maikaʻi o ka hoʻohana ʻana o kou kino i ka glycogen. ʻO ka poʻe me GSD pinepine he haʻahaʻa ke kō koko.
• ʻO ka ultrasound ʻōpū: Hiki i kēia hoʻāʻo kiʻi ke kōkua i kāu kauka e ʻike inā ua hoʻonui ʻia kou ake.
• ʻO ka biopsy ʻiʻo: Hiki i kāu kauka ke lawe i kahi ʻāpana liʻiliʻi o nā ʻiʻo mai kou ʻiʻo a i ʻole ke akepaʻa a ana i nā pae o ka glycogen a i ʻole nā ​​​​enzymes i loko.
• Ka hoʻāʻo ʻana i ka genetics: Hiki i kāu kauka ke ʻōlelo aku i ka hoʻāʻo genetic e ʻike inā loaʻa iā ʻoe ka gene no ka Glycogen Storage Disease.

He aha ka mea nui loa e pono ai kākou e hoʻomanaʻo mai kēia ʻatikala?

ʻAe, i kēia manawa ua maopopo paha iā ʻoe he mea nui ka glycogen no ka kaohi ʻana i ko mākou pae kō koko a me ka hāʻawi ʻana i ka ikehu no ka hoʻoikaika kino. ʻO ka mea pōmaikaʻi, he mea kakaikahi loa nā pilikia me ka hana ʻana a me ka hoʻohana ʻana i ka glycogen i loko o ko mākou kino.

ʻO ka mea maikaʻi loa hiki iā ʻoe ke hana no kāu mau pae glycogen, ʻoiai inā he mea pāʻani ʻoe, ʻo ia ka ʻai ʻana i nā kalapona lawa i kēlā me kēia lā. Inā he mau nīnau kāu e pili ana i kāu papaʻai a me nā pahuhopu hoʻoikaika kino, e kamaʻilio me kāu kauka a i ʻole kahi meaʻai meaʻai i kākau inoa ʻia. Hiki iā lākou ke hāʻawi iā ʻoe i ka ʻōlelo aʻoaʻo kūpono iā ʻoe.