He aha ka Acetylcholine (ACh)? E ʻike kākou i kāna hana i ko kākou kino!

Ua lohe paha ʻoe i ka acetylcholine , a i ʻole (ACh)? Malia paha ua haʻi aku kāu kauka iā ʻoe e pili ana i ia mea, a ua heluhelu paha ʻoe e pili ana i ia mea ma kekahi wahi. He kemika liʻiliʻi akā koʻikoʻi loa ia i loko o ko mākou kino. Ua like ia me kahi mea lawe leka liʻiliʻi e lawe ana i nā leka i loko o ko mākou kino. No laila, i kēia lā e kamaʻilio mākou e pili ana i ka acetylcholine ma ke ʻano maʻalahi hiki iā ʻoe ke hoʻomaopopo.

He aha maoli ka Acetylcholine?

I ka ʻōlelo maʻalahi, he neurotransmitter ka acetylcholine. E noʻonoʻo e pili ana i ia mea, pono kou lolo e hoʻouna i nā leka uila liʻiliʻi e hoʻoneʻe i kou lima, e noʻonoʻo, e hoʻomanaʻo i kekahi mea, i kēia mau mea āpau. He ʻelele kemika ʻo Acetylcholine e kōkua i ka lawe ʻana i kēlā mau leka ma o nā ʻaʻalolo .

Ua kapa ʻia hoʻi kēia he neurotransmitter " excitatory " . ʻIke anei ʻoe i ke ʻano o ia mea? "Hoʻāla" ia i kahi cell nerve, ʻo ia hoʻi, hoʻoulu iā ia, a hoʻolilo iā ia i "hoʻouna" i nā leka me ka wikiwiki. Ua like ia me ke kīkēkē ʻana ma ka puka o kahi mea hiamoe a ʻōlelo aku, "Eia, e lawe i kēia leka."

Loaʻa ka inoa acetylcholine mai ʻelua mau mea e hana ai. ʻO kekahi he hui acetyl . Loaʻa kēia mai kahi hui i kapa ʻia ʻo acetyl coenzyme A, i hana ʻia mai ke kō glucose. ʻO kekahi he meaʻai i kapa ʻia ʻo choline . Loaʻa maoli ʻo Choline i nā yolks hua manu, soy, ate, nā mea kanu, a me nā legumes. Hana ʻia ʻo Choline i loko o ko kākou ate.

Hoʻokomo ʻo Acetylcholine i nā hana koʻikoʻi he nui i loko o ko mākou kino, ʻoiai ke neʻe ʻana o nā ʻiʻo.He kuleana koʻikoʻi kēia i kā mākou hana ʻike, e like me ka hoʻoneʻe ʻana i ko mākou mau lālā a me ka hele wāwae. Hoʻoulu ia i nā hunaola aʻalolo i loko o ko mākou mau ʻiʻo, e hoʻoulu ai iā lākou e ʻūlū. ʻAʻole wale kēlā, akā he mea nui loa ia no nā hunaola aʻalolo i loko o ko mākou lolo, a no nā kaʻina hana e like me ka hoʻomanaʻo, ka noʻonoʻo ʻana, a me ke aʻo ʻana.

Pehea e hana ai ka acetylcholine (ACh)?

Mālama ʻia ʻo Acetylcholine ma nā wēlau o nā hunaola nerve, a hiki i ka wā e pono ai ke hoʻouna ʻia kahi leka. Ke hiki mai kahi "hōʻailona" e hoʻouna i kahi leka, hoʻokuʻu ʻia kēia acetylcholine i mālama ʻia. Ke hoʻokuʻu ʻia, hele ia i loko o kahi hakahaka liʻiliʻi ma waena o ʻelua mau hunaola nerve. Ua kapa ʻia kēia hakahaka ʻo ka synaptic cleft .

Ma hope o ke keʻa ʻana i ka māhele synaptic, aia ʻelua ʻano o nā mea loaʻa e hiki ai i ka acetylcholine ke hoʻopaʻa. ʻO lākou kēia:

• Nā mea hoʻokipa nikotinic
• Nā mea hoʻokipa Muscarinic

Ma hope o ka nakinaki ʻana i kēia mau mea loaʻa, hele ka leka kemika i ke kelepona nerve aʻe. Ma hope o ka hoʻouna ʻia ʻana o ka leka, ʻaʻole e lilo wale ka acetylcholine i koe i loko o ka synaptic cleft i mea ʻino. Hele mai kekahi enzyme i kapa ʻia ʻo acetylcholinesterase a wāwahi i kēia acetylcholine i loko o kona mau ʻāpana, ʻo choline a me acetate. A laila ua hoʻopili hou ʻia kēia mau ʻāpana i haki ʻia, hana hou ʻia, a hoʻohana ʻia e lawe i kahi leka kemika ʻē aʻe. He ʻōnaehana kūpono loa!

He aha ka mea e hana ʻia i ka acetylcholine (ACh)?

He nui nā pono o Acetylcholine no ko kākou kino. E nānā kākou i nā mea nui.

Pili nā ʻano mea loaʻa ʻelua i ko kākou hoʻomanaʻo . ʻO ia hoʻi, he mea nui lākou no ka hoʻomanaʻo lōʻihi, ka hoʻomanaʻo pōkole, ke kūkulu ʻana i nā hoʻomanaʻo, ko lākou hoʻopaʻa ʻana, a me ko lākou loaʻa hou ʻana. I loko o ka lolo, pili ka acetylcholine i nā mea ʻē aʻe. Hoʻoulu ia i ka hoʻoikaika, ka hoihoi/ka nānā ʻana, ke aʻo ʻana, a me ka hiamoe REM (ke kahua o ka hiamoe a kākou e moeʻuhane ai).

He aha nā kūlana e kū mai ana ke emi iho nā pae acetylcholine (ACh)?

ʻO nā pae haʻahaʻa o ka acetylcholine, a i ʻole ka hemahema, hiki ke alakaʻi i kekahi mau maʻi. ʻO nā mea nui loa o kēia mau mea:

• ʻO ka maʻi o Alzheimer : ʻAʻole lawa ka acetylcholine i loko o ka lolo o ka poʻe me ka maʻi o Alzheimer. ʻO ka hopena, ʻo ka nalowale o ka hoʻomanaʻo kahi hōʻailona nui.
• ʻO ka maʻi myasthenic Lambert-Eaton : Hoʻokumu ʻia kēia maʻi e ka emi ʻana o ka hoʻokuʻu ʻana o ka acetylcholine mai nā pūnaewele nerve.
• ʻO Myasthenia gravis : He maʻi autoimmune kēia e hoʻonāwaliwali koke ai nā ʻiʻo iwi ma hope o ka hoʻohana pinepine ʻana.

He aha nā lāʻau lapaʻau e hoʻopili ai i ka acetylcholine (ACh)?

ʻO nā mea hoʻopaʻa Cholinesterase kahi papa o nā lāʻau lapaʻau e hana ana ma ka hoʻopau ʻana i ka enzyme e wāwahi ana i ka acetylcholine a hoʻonui i ka hana o nā mea loaʻa acetylcholine. Hoʻohana ʻia lākou e mālama i ka maʻi Alzheimer a me ka myasthenia gravis. ʻO Donepezil (Aricept®), Rivastigmine (Exelon®), a me Galantamine (Razadyne®) kekahi o kēia mau lāʻau lapaʻau.

He aha nā meaʻai i loaʻa ka choline, ka mea e kōkua ai i ka hana ʻana i ka acetylcholine (ACh)?

ʻO Choline, kahi meaʻai e hoʻololi i ka acetylcholine, loaʻa i nā meaʻai he nui. Eia kekahi laʻana:

• ʻAke pipi
• Nā hua manu (ʻoi aku hoʻi nā yolks)
• Poʻai luna pipi
• ʻO ka soybeans i kālua ʻia, nā pīni puʻupaʻa i loko o ka pahu
• ʻŪhā moa i kālua ʻia
• Iʻa cod `(Cod)`
• Quinoa i moʻa ʻia
• Nā halo shiitake i kuke ʻia, broccoli i hoʻolapalapa ʻia a me nā ʻōpuʻu Brussels
• Waiū (1%) `(Waiū (1%))`, yogurt vanilla momona ʻole `(yogurt vanilla momona ʻole)`

E hoʻāʻo e hoʻohui i kēia mau meaʻai i kāu papaʻai. He mea nui loa ka papaʻai kaulike no ke ola olakino.