He aha ka Angioimmunoblastic T-cell Lymphoma (AITL)? E kamaʻilio maʻalahi kākou e pili ana!

Ua lohe paha ʻoe i kahi maʻi me ia inoa ʻē? Malia paha ua haʻi ʻia kēia inoa iā ʻoe a i ʻole kekahi āu i ʻike ai e ke kauka. ʻOiai he mea paʻakikī iki paha, e hoʻāʻo kākou e hoʻomaopopo maʻalahi. ʻO ka mea e hana ʻia ana, ʻo ia ke ʻano o kahi ʻano hunaola pale i loko o ko kākou kino i kapa ʻia ʻo "nā hunaola T" e lilo i mau hunaola maʻi kanesa.

He aha ka angioimmunoblastic T-cell lymphoma (AITL)?

I ka ʻōlelo maʻalahi, ʻo Angioimmunoblastic T-cell Lymphoma (AITL) kahi ʻano maʻi kanesa e ulu ana i loko o nā hunaola koko keʻokeʻo i loko o ko kākou koko i kapa ʻia ʻo T lymphocytes, a i ʻole nā ​​hunaola T. E noʻonoʻo iā ia e like me ka ʻōnaehana pale o ko kākou kino. Ke kaua nei lākou i nā mea ʻino e like me nā virus a me nā bacteria e komo i loko o ko kākou kino a pale iā kākou mai nā maʻi. I kekahi manawa, hiki i kēia mau hunaola T ke luku i nā hunaola kanesa.

Eia nō naʻe, i kekahi manawa hiki i kekahi o kēia mau 'T cell' ke loli, ʻo ia hoʻi, e loli, a lilo i cell kanesa. A laila hoʻomaka kēia mau cell kanesa ʻino e māhele wikiwiki a hoʻonui me ke kāohi ʻole. ʻO ia ka manawa e kū mai ai kēia kūlana i kapa ʻia ʻo 'AITL'. He kanesa kēia e hāʻule ana i loko o kahi hui liʻiliʻi i kapa ʻia ʻo 'peripheral T-cell lymphoma', nona ka hui nui i kapa ʻia ʻo 'non-Hodgkin T-cell lymphoma'. Hiki i kēia kanesa ke laha i nā wahi e like me ko kākou ake, nā māmā, a i ʻole 'bone marrow'.

Pehea ka maʻamau o kēia ʻano i kapa ʻia ʻo AITL?

ʻO kaʻoiaʻiʻo, he ʻano maʻamau ka AITL o ka lymphoma T-cell, akā ma ke ʻano holoʻokoʻa he maʻi kanesa kakaikahi loa ia. No ka laʻana, ma kahi ʻāina e like me ʻAmelika Hui Pū ʻIa, ʻo AITL wale nō ka 4% o nā maʻi lymphoma āpau. Loaʻa pū kekahi iā 1% a 2% o nā maʻi lymphoma non-Hodgkin āpau. ʻO ia ka mea maʻamau i nā poʻe ma luna o 65 mau makahiki .

He aha nā hōʻailona o AITL?

No ka mea, he maʻi kanesa wikiwiki ka AITL, hiki ke ʻike koke ʻia nā hōʻailona. Inā loaʻa iā ʻoe kekahi o kēia mau mea, pono ʻoe e hopohopo:

• Ke kuni e hele mai a hele aku me ke kumu ʻole: Wela wale ke kino a hele mai ke kuni, nalo aku, a hoʻi hou mai. ʻAʻohe kumu kikoʻī i loaʻa.
• Hou i ka pō: Hou nui i ka wā hiamoe a pulu nā moena moe.
• Ka maneʻo a i ʻole ka hoʻonāukiuki ʻana o ka ʻili: Hiki ke ʻike ʻia ma ke kino holoʻokoʻa, ma nā wahi kiko, a i ʻole hiki ke maneʻo mau.
• Paʻakikī ka hanu ʻana: Manaʻo i ka pōkole o ka hanu ʻoiai me ka hoʻoikaika iki ʻana.
• Pehu hui: Hiki i nā hui ma nā lālā ke pehu a ʻeha paha.
• Nā nipples pehu: ʻIke ʻia lākou he mau puʻupuʻu ma nā wahi e like me ka ʻāʻī, nā armpits, a me ka ʻūhā. ʻAʻohe pinepine kēia mau mea ʻeha.
• ʻO ka pohō kaumaha me ke kumu ʻole: E pohō koke kou kaumaha, ʻoiai inā ʻaʻole ʻoe e kaohi nui i kāu ʻai a hoʻoikaika kino paha.

Ma muli o ka hoʻopilikia ʻana o AITL i kā mākou ʻōnaehana pale kino , hiki i kekahi poʻe me ke ʻano ke hoʻomohala i nā kūlana i kapa ʻia he mau maʻi autoimmune, ʻo ia hoʻi nā maʻi e kūʻē ai ko mākou ʻōnaehana pale kino iā mākou. No ka laʻana, nā kūlana e like me ka immune thrombocytopenia (nā platelet koko haʻahaʻa) a i ʻole ka anemia hemolytic autoimmune (ka luku ʻia ʻana o nā hunaola koko).

He aha ke kumu o ka AITL?

Hana ʻia ka AITL ke lilo kā mākou mau pūnaewele T i mea ʻē aʻe a hoʻomaka e ulu ma waho o ke kaohi. Eia nō naʻe, ʻaʻole maopopo i nā mea noiʻi ke kumu e loaʻa ai i kekahi poʻe kēia ʻano lymphoma T-cell a ʻo kekahi ʻaʻole.

Aia kahi hiki ke loaʻa kahi pilina ma waena o AITL a me nā maʻi viral e like me ka maʻi Epstein-Barr. Eia nō naʻe, pono ka ʻike hou aku e hoʻomaopopo ai pehea e hana ai kēia loulou.

Pehea e ʻike ʻia ai ka AITL?

Hoʻomaopopo pinepine ʻia ka AITL ma o kahi biopsy lymph node . Pili kēia i ka lawe ʻana i kahi hāpana liʻiliʻi o ka ʻiʻo mai kahi lymph node pehu a i ʻole kahi mea kānalua a nānā iā ia ma lalo o kahi microscope. Inā hōʻike nā hopena o kāu hoʻāʻo i nā lymphocytes T ʻē, e kānalua nā kauka iā AITL.

Ke hōʻoia ʻia ka hōʻailona, ​​e nānā ke kauka maʻi ʻōpū iā ʻoe a nīnau e pili ana i kāu mau hōʻailona. E nīnau pū lākou e pili ana i kou mōʻaukala olakino, e like me nā maʻi ma mua a me nā lāʻau lapaʻau o kēia manawa.

Eia kekahi, hiki i ke kauka ke hana i kekahi mau hoʻokolohua, e like me:

• Nā hoʻāʻo koko.
• ʻO ka biopsy iwi.

Hiki paha iā ʻoe ke loaʻa nā hoʻokolohua kiʻi e like me kēia:

• ʻO ke kiʻi CT (CT - nā kiʻi tomography i helu ʻia).
• MRI scan (MRI - nā scan kiʻi resonance magnetic).
• ʻO ke scan PET (nā scan tomography hoʻokuʻu positron).

Hiki ke paʻakikī ke ʻike i ka AITL, e like me nā lymphoma ʻē aʻe. ʻO kēia no ka mea he paʻakikī ka maʻi, a hiki ke ulu mālie nā hōʻailona a hiki ke hoʻohālike i nā maʻi ʻē aʻe. No kēia mau kumu, ua ʻike ʻia ka nui o nā maʻi AITL me ka maʻi i ka wā hope . Eia nō naʻe, ke hoʻomau nei nā mea noiʻi i ka ʻimi ʻana i nā ala e ʻike koke ai i ka AITL a me nā lymphoma ʻē aʻe.

Pehea e mālama ʻia ai ʻo AITL?

ʻO ka mālama ʻana no AITL e pili ana i nā kumu he nui, me kou mau hōʻailona, ​​​​ke koʻikoʻi o ka maʻi, a me kou olakino holoʻokoʻa. ʻO nā lāʻau lapaʻau nui no AITL:

• Kemokalama:ʻO kēia ka hāʻawi ʻana i ka hui pū ʻana o nā lāʻau lapaʻau like ʻole e pepehi i nā hunaola kanesa. Hoʻohui pū ʻia nā steroid i kēia. ʻO nā lāʻau lapaʻau i hoʻohana pinepine ʻia ʻo CHOP a me BV+CHP. ʻO ka inoa CHOP he acronym no Cytoxan (cyclophosphamide), Hydroxydaunorubicin (hydroxydaunorubicin), Oncovin (vincristine sulfate), a me Prednisone. ʻO BV+CHP ka hui pū ʻana o brentuximab vedotin, cyclophosphamide, doxorubicin, a me prednisone. He mea paʻakikī iki kēia, akā na kāu kauka e wehewehe iā ʻoe.

• Hoʻoili ʻana i nā pūnaewele kumu: Pili kēia i ka wehe ʻana i nā pūnaewele kumu maʻi kanesa a hoʻololi iā lākou me nā pūnaewele kumu olakino. Hiki ke lawe ʻia kēia mau pūnaewele olakino mai ou aku (`autologous`) a i ʻole hiki ke hāʻawi ʻia mai kekahi mea ʻē aʻe (`allogeneic`).

• Lapaʻau i kuhikuhi ʻia: Ke nānā wale nei kēia lāʻau lapaʻau i nā hoʻololi genetic e hoʻololi i nā cell olakino i nā cell kanesa. ʻO ke ʻano kēia, hele pololei ka lāʻau i nā cell ʻino a hana wale ma kēlā mau cell ʻino.

ʻEhia ka lōʻihi e hiki ai iā ʻoe ke ola me AITL?

He maʻi kanesa ʻino loa ʻo AITL. Hōʻike ka noiʻi ʻana ʻo ka awelika o ke ola ma hope o ka hōʻoia ʻana he emi ma mua o ʻekolu mau makahiki . ʻO ka "median" ka waiwai waena i loko o kahi pae o nā waiwai. ʻO ia hoʻi, ola kekahi poʻe i nā ola pōkole, aʻo kekahi e ola lōʻihi.

Akā eia kahi mea nui: Ma kahi o 30% a 35% o ka poʻe me AITL e pane maikaʻi i ka lāʻau lapaʻau a hiki ke ho'ōla ʻia me ka ʻole o ka hoʻi hou ʻana mai o ke kanesa.

Ka helu ola no AITL

ʻO ka nui o ke ola ʻana o ʻelima makahiki no AITL ma waena o 30% a me 35% . ʻO ke ʻano kēia, mai loko mai o 100 mau kānaka i ʻike ʻia me AITL, ma waena o 30 a me 35 e ola mau ana ma hope o ʻelima mau makahiki. Pēlā nō, ʻo ka nui o ke ola ʻana o ʻehiku makahiki ma kahi o 29%.

He mea maʻamau ka makaʻu a me ka hopohopo ke ʻike ʻoe i kēia mau helu. Akā e hoʻomanaʻo, he mau kuhi wale nō kēia. Hoʻokumu ʻia lākou ma nā ʻike o nā poʻe ʻē aʻe i loaʻa i ka maʻi like me ʻoe. He ʻokoʻa ka mōʻaukala olakino a me ke kumu hoʻoilina o kēlā me kēia kanaka. No laila, ʻaʻole hiki i kēia mau helu ola ke wānana pololei i ka lōʻihi o kou ola ʻana a pehea ʻoe e pane ai i ka lāʻau lapaʻau.

Inā ʻoe e hopohopo nei e pili ana i kēia mau helu helu, a inā makemake ʻoe e ʻike pehea lākou e pili ai iā ʻoe, e kamaʻilio me kāu kauka. Hiki iā ia ke wehewehe i kou kūlana a hāʻawi i kekahi kōkua āu e pono ai.

Hiki ke pale ʻia ka AITL?

ʻAʻohe kumu pilikia i ʻike ʻia no ka hapa nui o ka poʻe me AITL no ka hoʻomohala ʻana i ka maʻi. ʻAʻohe ala kikoʻī e pale aku ai i ka AITL a i ʻole kekahi ʻano lymphoma ʻē aʻe. E like me ka hapa nui o nā maʻi kanesa, he mea kēia e hana ʻia i kekahi manawa. ʻAʻole ia he manaʻo ua hana hewa ʻoe.

Hiki iaʻu ke hōʻemi i koʻu pilikia?

ʻOiai ʻaʻole hiki iā ʻoe ke pale aku i ka angioimmunoblastic T-cell lymphoma, hiki iā ʻoe ke hana i kēia mau mea e mālama ai i kahi ʻōnaehana palekana olakino :

• E ʻai i ka ʻai kaulike: E ʻai i nā meaʻai waiwai i nā mea kanu, nā huaʻai, nā legumes, nā palaoa piha, a me ka protein, e like me nā ʻiʻo momona a me nā iʻa.
• E hoʻoikaika kino mau: E hana i kekahi mea e like me ka hele wāwae a i ʻole ka holo ʻana no 30 mau minuke i ka lā.
• E hiamoe maikaʻi: E hiamoe maikaʻi ma ka liʻiliʻi he 7-8 mau hola i ka lā.
• E mālama i kahi kaumaha olakino e kūpono iā ʻoe.
• E pale i ka puhipaka a me ka hoʻohana ʻana i ka paka: E like me nā cigarettes a me nā bidis, he mea ʻino nō hoʻi ka paka uahi ʻole (e like me ka paka nau a me ka chewing gum). ʻAʻole maikaʻi hoʻi ka vaping.
• E kaupalena i ka inu ʻana i ka waiʻona.

Āhea wau e ʻike ai i ke kauka?

Inā loaʻa iā ʻoe nā hōʻailona e like me ka ʻulaʻula koke, nā ʻōpū lymph pehu, ke kuni nui, a i ʻole ka pohō kaumaha i manaʻo ʻole ʻia, e ʻike koke i ke kauka.

Inā ʻoe e mālama ʻia nei no AITL, e hoʻomaopopo koke i kāu kauka maʻi kanesa inā loaʻa iā ʻoe nā hōʻailona hou a i ʻole inā e ʻoi koke aʻe kou mau hōʻailona. Ma muli o ke ʻano o kēia maʻi kanesa, he mea nui loa ia e hoʻomaka i ka mālama ʻana i ka wā hikiwawe loa.

Hoʻopilikia ka AITL i kēlā me kēia kanaka i kekahi ʻano like ʻole. ʻO kāu kauka wale nō ke kanaka hiki ke wehewehe pehea e hoʻopilikia ai kāu hōʻailona iā ʻoe. ʻAʻole makemake kekahi poʻe e ʻike i nā kikoʻī o ka maʻi, a he mea maikaʻi kēlā. Loaʻa iā ʻoe ke kuleana e hoʻoholo i kāu lāʻau lapaʻau. ʻO ʻoe wale nō ka mea ʻike i ka mea maikaʻi loa no kou olakino noʻonoʻo, naʻau, a me ka ʻuhane.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

He mea maʻamau ka loaʻa ʻana o nā nīnau he nui ma hope o ka ʻike ʻia ʻana o AITL. Eia kekahi mau nīnau hiki iā ʻoe ke nīnau aku i kāu kauka oncology:

• Pehea ka holomua o koʻu maʻi kanesa?
• Ua laha anei ke kanesa i koʻu mau kino ʻē aʻe?
• He aha nā koho lapaʻau e loaʻa iaʻu?
• Pehea ka wikiwiki e hoʻomaka ai au i ka lāʻau lapaʻau?
• Hiki iaʻu ke hoʻomau i kaʻu hana ʻoiai e loaʻa ana ka lāʻau lapaʻau?
• He aha ke ʻano o ke kākoʻo a me ke kōkua e pono ai iaʻu i ka wā o ka mālama ʻana?
• Hiki iaʻu ke hui pū me nā hui kākoʻo a i ʻole nā ​​​​​​kumuwaiwai ʻē aʻe?
• Pehea e mālama ai i koʻu olakino noʻonoʻo?

Hiki i ka maʻi kanesa ke lawe mai i nā ʻano manaʻo paʻakikī like ʻole, me ke kaumaha, ka hopohopo, ka huhū, a me ka huhū. No ka mea he maʻi laha ʻole ka AITL, hiki iā ʻoe ke manaʻo mehameha a me he mea lā ʻaʻohe mea e hoʻomaopopo iā ʻoe.Akā, aia kāu hui lapaʻau ma laila e kōkua iā ʻoe. Hiki iā lākou ke haʻi iā ʻoe e pili ana i nā kumuwaiwai āu e pono ai, a me nā hui kākoʻo me nā poʻe i ʻike i nā mea like me ʻoe. ʻAʻole pono ʻoe e hele wale ma kēia huakaʻi. E kiʻi i ke kākoʻo o kāu poʻe aloha a me kāu mau kauka.

Leka Lawe-Home

He maʻi ʻaʻai koʻikoʻi a laha ʻole ka AITL. Eia nō naʻe, he mea nui e makaʻala iā ia, e makaʻala i nā hōʻailona, ​​a e ʻimi koke i ke kōkua lapaʻau.

• E hoʻomaopopo i nā hōʻailona: E makaʻala i ke kuni i wehewehe ʻole ʻia, ka hou ʻana o ka pō, nā kuʻekuʻe wāwae pehu, nā pilikia ʻili, ka paʻakikī o ka hanu ʻana, nā hono pehu, a me ka pohō kaumaha.
• E ʻimi i ke kōkua lapaʻau: Inā kānalua, e ʻike koke i ke kauka. He mea nui loa ka ʻike koke ʻana a me ka mālama ʻana.
• Aia nā lāʻau lapaʻau: Aia nā koho e like me ka chemotherapy, nā hoʻoili cell stem, a me nā lāʻau lapaʻau i kuhikuhi ʻia. Na kāu kauka e hoʻoholo i ka mea maikaʻi loa iā ʻoe.
• ʻAʻole ʻoe hoʻokahi: Hiki ke paʻakikī kēia huakaʻi, akā he ʻohana kou, nā hoaaloha, a me kahi hui lapaʻau e kōkua iā ʻoe. E kiʻi i kā lākou kākoʻo.
• E noho maikaʻi: ʻAʻole nā ​​helu helu nā mea āpau. He ʻokoʻa nā kānaka a pau. E noho lana ka manaʻolana.

Manaʻolana wau ua kōkua kēia ʻike iā ʻoe e hoʻomaopopo i kēia maʻi. E hoʻomanaʻo, ʻoi aku ka maikaʻi o ka ʻimi ʻana i ka ʻōlelo aʻoaʻo lapaʻau no kekahi pilikia olakino.

ʻAITL , Angioimmunoblastic T-cell Lymphoma, T-cell lymphoma, maʻi ʻaʻai, maʻi ʻaʻai koko, nā hōʻailona lymphoma, ka mālama ʻana i ka maʻi ʻaʻai