I ka wā e hoʻouka ai kou kino ponoʻī i kou lolo? (Autoimmune Encephalitis) E aʻo kākou e pili ana i ia mea.

Ua noʻonoʻo paha ʻoe i ka mea e hiki mai ana inā hoʻomaka ka ʻōnaehana pale o kou kino ponoʻī, ʻo ia hoʻi ka ʻōnaehana pale , e hana kūʻē i kou lolo ponoʻī? He mea weliweli iki ia, ʻeā? ʻO ia ke ʻano o ke kūlana a mākou e kamaʻilio ai i kēia lā, i kapa ʻia ʻo Autoimmune Encephalitis (AE). I ka ʻōlelo maʻalahi, he aha ka mea e hiki mai ana i ka wā e hoʻouka hewa ai kā mākou ʻōnaehana pale, ka mea e hana ana e like me ke kiaʻi i loko o ko mākou kino, i nā ʻāpana olakino i loko o ko mākou lolo ponoʻī a me nā mea e lawe ana i nā leka ma waena o lākou. Ua like ia me ko mākou kiaʻi palekana hale e manaʻo nei he ʻaihue mākou a hoʻouka mai iā mākou.

No laila he aha kēia encephalitis autoimmune?

ʻAe, e wehewehe iki kākou. ʻAʻole he maʻi hoʻokahi ka Autoimmune Encephalitis (AE), he hui ia o nā maʻi. I loko o kēlā me kēia, aia ka mumū , a i ʻole ka pehu ʻana, i loko o kou lolo. ʻO kēia no ka mea, e like me ka mea i ʻōlelo ʻia ma mua, ua hoʻouka hewa kāu ʻōnaehana pale i kekahi mau protein a me nā neurotransmitters i loko o nā hunaola nerve olakino o kou lolo. E noʻonoʻo e pili ana, ua like ko mākou lolo me kahi ʻōnaehana kamepiula paʻakikī. Ua like kēia mau hunaola nerve a me nā neurotransmitters me nā uea a me nā hōʻailona i loko. No laila, i ka wā e hoʻouka ai ka ʻōnaehana pale iā ia, hele hewa ka ʻōnaehana holoʻokoʻa. ʻO ia ke kumu e kū mai ai nā hōʻailona e like me ka nalowale o ka hoʻomanaʻo, nā hopu ʻana, a me ka psychosis .

He aha nā hōʻailona o kēia? Pehea mākou e ʻike ai?

No ka mea, he ʻano like ʻole o ka encephalitis autoimmune, hiki ke ʻokoʻa loa nā hōʻailona. Eia kekahi, ʻaʻole e ʻike koke ʻia kēia mau hōʻailona. Hoʻomohala mālie lākou i loko o kekahi mau pule a i ʻole nā ​​​​mahina. Inā loaʻa iā ʻoe a i ʻole kekahi āu i ʻike ai kēia mau hōʻailona, ​​​​he mea nui e ʻimi koke i ke aʻo lapaʻau.

Eia kekahi mau mea āu e ʻike ai:

• Ke manaʻo nei e emi mālie ana kou hiki ke noʻonoʻo. Me he mea lā e lohi iki ana kou lolo.
• Nā pilikia hoʻomanaʻo. Lilo i mea paʻakikī ke hoʻomanaʻo i nā mea hou, a hiki paha iā ʻoe ke poina i nā mea kahiko.
• Huikau. ʻAʻole hiki iā ʻoe ke hoʻomaopopo i kou wahi a i ʻole kāu mea e hana nei.
• Nā ʻūhū. He mea paʻakikī kēia i kekahi manawa ke kāohi me nā lāʻau lapaʻau epilepsy maʻamau.
• Nā neʻe ʻano ʻē. Eia kekahi laʻana, nā neʻe ʻana o ka waha a me ka maka e hana hou ʻia ana, ka ʻūlū ʻana o nā ʻiʻo, a me ka pane pūʻiwa i kahi mea liʻiliʻi loa ('pane pūʻiwa nui ʻia').
• Paʻakikī i ka ʻōlelo ʻana (aphasia). Paʻakikī i ka hoʻokumu ʻana i nā huaʻōlelo a me ka hōʻike ʻana i nā manaʻo.
• Ka nalowale o ke kaulike (ataxia) a i ʻole nā ​​pilikia hoʻonohonoho i ka wā e hele ana. Hiki iā ʻoe ke hele e like me ka mea ʻona.
• Nā maʻi noʻonoʻo ('Psychosis').Hiki i kēia ke komo pū me ka ʻike ʻana, ka lohe ʻana, a me ka manaʻo ʻana i nā mea ʻoiaʻiʻo ʻole (hallucinations). Hiki iā ia ke alakaʻi i nā delusions a me ka paranoia, ʻo ia hoʻi nā manaʻo wahaheʻe a kekahi e hoʻāʻo nei e hōʻeha iā ʻoe.

He mea nui: Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona, ​​ʻaʻole ia he manaʻo he Autoimmune Encephalitis kou. Eia nō naʻe, inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ​​​​ʻoi aku ka maikaʻi o ke ʻike koke ʻana i ke kauka kūpono a hoʻāʻo ʻia.

He aha nā pilikia ʻē aʻe e hiki ai i kēia ke hana?

Hiki i ka encephalitis autoimmune ke alakaʻi i nā pilikia inā ʻaʻole mālama pono ʻia, ʻo ia ke kumu he mea nui e ʻike i ka maʻi a hoʻomaka i ka lāʻau i ka wā hikiwawe loa.

• Ka hemahema mau loa o ka hiki ke noʻonoʻo ('Cognitive impairment').
• Nā kūlana epileptic lōʻihi ('status epilepticus').
• Koma.
• Hiki ke make. Akā, ʻoi aku ka nui o kēia inā ʻaʻole ʻimi ʻia ka lāʻau lapaʻau a inā hoʻopaneʻe ʻia ka lāʻau lapaʻau.

No ke aha lā kēia iā kākou? He aha nā kumu?

Manaʻo nā kānaka noiʻi e hana ʻia ka encephalitis autoimmune i ka wā e hana ai kā mākou ʻōnaehana pale i nā antibodies e kūʻē i nā protein kikoʻī ma ka ʻili o kā mākou mau hunaola nerve ponoʻī a i loko paha o lākou. Hoʻopaʻa kēia mau antibodies i kēlā mau protein a hoʻōki iā lākou mai ka hana ʻana. Hoʻoulu kēia i ka mumū i loko o ka lolo.

E like me nā maʻi autoimmune he nui, ʻaʻole maopopo loa ke kumu e hoʻouka ai kā mākou ʻōnaehana pale i nā cell olakino ma kēia ʻano. I kekahi mau hihia, hiki ke hana ʻia ka autoimmune encephalitis (AE) me ka maʻi kanesa. Kāhea nā kauka i kēia paraneoplastic AE. I nā hihia ʻē aʻe, hiki i nā maʻi e like me ka herpes simplex virus ke hana iā ia. Eia nō naʻe, no ka hapa nui o ka poʻe, ʻaʻohe mea i ʻike ʻia no ka AE.

ʻO wai ka mea i pilikia nui i ka loaʻa ʻana o kēia maʻi?

Inā loaʻa iā ʻoe kēia mau mea, ʻoi aku ka nui o kou loaʻa ʻana i ka encephalitis autoimmune:

• Inā loaʻa iā ʻoe ka maʻi kanesa a inā paha e loaʻa iā ʻoe kahi maʻi kanesa hou, ʻoiai hoʻi ka maʻi kanesa o ka māmā liʻiliʻi, ka thymoma, a me ka maʻi kanesa ovarian .
• Inā ua lawe ʻoe i kekahi mau lāʻau lapaʻau pale kino (nā mea hoʻopale i ka nānā ʻana o ka pale kino) no ka maʻi kanesa .
• Inā ua loaʻa iā ʻoe kahi maʻi o ka lolo (infectious encephalitis) .

Eia nō naʻe, he mea nui e hoʻomanaʻo e hiki i ka autoimmune encephalitis (AE) ke ulu aʻe me ka ʻole o kekahi o kēia mau mea pilikia.

Pehea e ʻike ʻia ai kēia maʻi? He aha nā hoʻokolohua e pono ai?

Hoʻoponopono nā kauka i ka encephalitis autoimmune e pili ana i nā hōʻailona e kū mai ana i kahi manawa a me nā hopena hoʻāʻo e hōʻike ana i ka mumū i loko o kou lolo.

ʻOiai he nui nā kūlana ʻē aʻe e hiki ke hoʻoulu i nā hōʻailona like me kēia kūlana 'AE', pono paha ʻoe e hana i kekahi mau hoʻokolohua. I kekahi manawa hiki ke hala i nā pule e loaʻa ai kahi hōʻailona. Mai hopohopo, e hana nā kauka i ka mea maikaʻi loa iā ʻoe.

Eia kekahi o nā hoʻokolohua a me nā ʻano hana i hoʻohana ʻia e ʻike ai i ka AE:

• Hoʻokolokolo kino a me ka lawe ʻana i kāu mōʻaukala olakino piha.
• He hoʻokolokolo kūikawā e pili ana i ka ʻōnaehana nerve ('Neurological exam`).
• Nā hoʻokolohua noʻonoʻo.
• Nā hoʻāʻo koko.
• Nā hoʻokolohua kiʻi lolo. Eia kekahi laʻana, kahi scan MRI lolo ('Brain MRI').
• He hoʻāʻo e pili ana i ka lawe ʻana i ka wai cerebrospinal ('Spinal tap`).
• Hoʻāʻo EEG (Electroencephalogram). Ke ana kēia i ka hana uila o ka lolo.

Hiki i kāu kauka ke ʻōlelo i nā hoʻokolohua hou aʻe e hoʻopau i nā kūlana olakino ʻē aʻe.

He aha nā lāʻau lapaʻau no kēia?

ʻElua mau pahuhopu nui i ka mālama ʻana i ka autoimmune encephalitis: ke kāohi ʻana i ka ʻōnaehana pale (immunosuppression) a me ka wehe ʻana i kahi puʻupuʻu, inā loaʻa.

Lapaʻau laina mua

Hana kēia mau lāʻau lapaʻau ma ka hoʻemi ʻana i ka mumū ma ka lolo.

• Corticosteroids - He mau lāʻau lapaʻau ikaika kēia e hōʻemi ana i ka mumū.
• ʻO nā immunoglobulins IV (IVIG) - He hopena kēia e loaʻa ana nā antibodies olakino. Hāʻawi ʻia lākou ma ke ʻano intravenous.
• Plasmapheresis - He kaʻina hana kēia kahi e wehe ʻia ai nā antibodies ʻino mai kou koko a hoʻihoʻi ʻia ke koko i hoʻomaʻemaʻe ʻia i kou kino.

He aha inā ʻaʻole holomua kēia lāʻau lapaʻau?

Inā ʻaʻole i hāʻawi nā lāʻau lapaʻau mua i nā hopena i makemake ʻia, hiki i nā kauka ke noʻonoʻo i nā lāʻau lapaʻau ʻē aʻe, e like me:

• ʻO Rituximab - He ʻano lāʻau pale monoclonal kēia.
• Cyclophosphamide - Hoʻohana ʻia kēia ma ke ʻano he lāʻau lapaʻau chemotherapy.

He aha inā he puʻupuʻu?

Inā ua ʻike ʻia ʻoe me kahi puʻupuʻu, hiki i kāu hui lapaʻau ke ʻōlelo aku i ka wehe ʻana i ke ʻoki kino a/a i ʻole chemotherapy . Hiki i kēia ke kōkua i ka wikiwiki o ka ho'ōla ʻana o kou maʻi AE.

Ka mālama ʻana i nā hōʻailona

Pono paha ʻoe i nā lāʻau lapaʻau hou e kāohi i nā hōʻailona o AE:

• Nā lāʻau lapaʻau antiseizure- Hōʻemi a pale paha i nā hopu ʻana o ka epileptic.
• Nā lāʻau lapaʻau e mālama ai i ka hopohopo a me ke kaumaha. ʻO nā laʻana e komo pū me nā antidepressants a me nā anxiolytics.
• Inā he maʻi noʻonoʻo ('psychosis'), a laila hāʻawi ʻia nā lāʻau lapaʻau no ia mea ('Nā lāʻau lapaʻau Antipsychotic').

Eia kekahi, hiki i ka hoʻoikaika kino, ka hoʻoikaika hana, a me/a i ʻole ka hoʻoikaika ʻōlelo ke kōkua nui i ka wikiwiki ʻana o kou hoʻōla ʻana.

I ka nui hea e hiki ai ke ho'ōla ʻia kēia maʻi?

ʻOkoʻa ka holomua o ka mālama ʻana no ka autoimmune encephalitis (AE) mai kēlā me kēia kanaka. Pane maikaʻi kekahi poʻe i nā lā mua o ka mālama ʻana. Pono paha kekahi e lawe i ka lāʻau no nā pule a i ʻole nā ​​mahina.

He mea paʻakikī i nā kauka ke wānana pololei i ke ʻano o ka pane ʻana o kou kino i ka lāʻau lapaʻau. Akā e nānā pono lākou i kou kūlana a hoʻomaopopo iā ʻoe. E hilinaʻi e kōkua nā kauka iā ʻoe.

He aha ka wānana no kekahi me kēia maʻi?

Ma keʻano laulā, inā ʻike ʻia a mālama ʻia ka encephalitis autoimmune i ka wā mua, hiki ke hoʻemi ʻia ka pilikia o nā pilikia lōʻihi a me ka hoʻi hou ʻana.

Akā, ʻaʻole like ka AE no nā kānaka a pau. Inā loaʻa iā ʻoe nā maʻi ʻē aʻe, e like me ke kanesa, hiki i kēlā ke hoʻopilikia i kou nānā ʻana. Hiki i kāu hui lapaʻau ke hāʻawi iā ʻoe i kahi manaʻo maikaʻi o ka mea e manaʻo ai.

He maʻi anei kēia no ke ola holoʻokoʻa?

I ka hapa nui o ka manawa, pane maikaʻi ka encephalitis autoimmune i ka lāʻau lapaʻau a lilo i mea maikaʻi. Eia nō naʻe, no kekahi poʻe, hiki i kēia ke lōʻihi ka manawa. Eia kekahi, hiki i ka AE ke hoʻi hou mai (relapse), ʻoiai inā ʻaʻole pane maikaʻi kāu maʻi ʻaʻai i ka lāʻau lapaʻau.

He maʻi koʻikoʻi ka Autoimmune encephalitis e pono ai ke kōkua koke ʻia e ke kauka. No ka mea, he ʻokoʻa nā ʻano, hiki ke ʻokoʻa nā hōʻailona, ​​a hiki ke lōʻihi ka manawa e ʻike ai i ke ʻano. Eia nō naʻe, e hoʻomanaʻo e hana pū ana kāu hui lapaʻau e ʻike i ke ʻano a hoʻomaka i ka mālama ʻana i ka wā hikiwawe loa.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai

Hiki ke hopohopo iki ka inoa Autoimmune Encephalitis, akā ʻo ka ʻike ʻana iā ia hiki ke kōkua iā ʻoe e hana koke inā ʻike ʻia nā hōʻailona.

• ʻO ka mea e hana ʻia ana ma kēia, ʻo ia ka hoʻouka ʻana o kāu ʻōnaehana pale ponoʻī i kou lolo.
• Hiki ke ʻike ʻia nā hōʻailona e like me nā pilikia hoʻomanaʻo, ka huikau, ka maʻi epilepsy, nā neʻe ʻokoʻa, ka paʻakikī i ka ʻōlelo ʻana, a me nā loli noʻonoʻo.
• Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​e ʻike pono i ke kauka.
• He mea nui loa ka ʻike ʻana i ka maʻi a hoʻomaka i ka lāʻau lapaʻau i ka wā mua.
• Aia ka lāʻau lapaʻau, a ua ho'ōla ʻia nā kānaka he nui.
• I kekahi manawa hiki ke hoʻi hou mai ka maʻi, no laila he mea nui e hahai i ka ʻōlelo aʻoaʻo a ke kauka.

Inā he mau nīnau hou kāu a i ʻole kekahi āu i ʻike ai e pili ana i kēia, mai makaʻu e kamaʻilio me ke kauka. Hauʻoli nui lākou e kōkua iā ʻoe.

ʻO ka Encephalitis Autoimmune, ka mumū o ka lolo, ka ʻōnaehana pale, ka nalowale o ka hoʻomanaʻo, ka maʻi Epilepsy, ka maʻi noʻonoʻo