Loaʻa iā ʻoe kahi puʻupuʻu ʻeha ʻole ma kou ʻāʻī, armpit, a i ʻole groin? A i ʻole ua hoʻopilikia ʻia ʻoe e ka hou nui ʻana a pulu kou mau pale i ka pō? Hiki ke maʻamau kēia mau mea, akā i kekahi manawa hiki ke lilo i mau hōʻailona o kahi ʻano maʻi koko i kapa ʻia ʻo B-Cell Lymphoma. Mai makaʻu i kou lohe ʻana i kēia inoa. ʻAʻole paʻakikī ke hoʻomaopopo. E kamaʻilio kākou e pili ana i ia mea me ka maʻalahi, me ka maopopo, a ma ke ʻano e hiki ai iā ʻoe ke hoʻomaopopo.
I ka ʻōlelo maʻalahi, he aha ka B-Cell Lymphoma?
ʻO ka lymphoma B-cell kahi ʻano maʻi koko e ulu ana i loko o kā mākou ʻōnaehana lymphatic. ʻAe, e hoʻomaʻalahi hou aku kākou i kēia.
Aia i loko o ko kākou koko kahi ʻano o ke keʻena i kapa ʻia he mau keʻokeʻo koko. Ua like kēia me ka pūʻali koa ponoʻī o ko kākou kino. Mālama kēia mau keʻena iā kākou ma ke kaua ʻana i nā huakini e hoʻoulu ai i nā maʻi. ʻO kekahi ʻano o ke keʻokeʻo koko i kapa ʻia he lymphocytes. Ma waena o kēia mau lymphocytes, aia kekahi ʻano kūikawā i kapa ʻia he mau keʻena-B. ʻO lākou ka ʻāpana nui o ka pūʻali koa pale o ko kākou kino.
Ke ulu ka lymphoma B-cell, hewa kekahi mea me kēia mau B-cell, e hoʻoulu ai iā lākou e māhele a hoʻonui me ke kāohi ʻole, e lilo i mau cell cancerous a hana i nā tumors.
ʻO kā mākou ʻōnaehana lymphatic he pūnaewele o nā kīʻaha koko, nā lymph node, a me nā ʻiʻo i hohola ʻia ma ko mākou kino. Ua like ia me ka ʻōnaehana holo kaʻa lua i loko o ko mākou kino. ʻO ia ke kumu e hiki ai i ka lymphoma B-cell ke ulu i nā wahi āpau o ke kino. ʻO ia ke kumu e ʻokoʻa ai nā hōʻailona mai kēlā kanaka a i kēia kanaka.
ʻO ka mea nui, ʻo ka lymphoma B-cell ke ʻano maʻamau o ka lymphoma non-Hodgkin. I ka hapa nui o nā hihia, aia nā lāʻau lapaʻau kūpono. Hiki ke ho'ōla loa ʻia kekahi mau ʻano. I nā mea ʻē aʻe, hiki ke hoʻemi ʻia nā hōʻailona a hiki ke mālama ʻia ke kanesa i ka hoʻomaha ʻana.
Ua māhele ʻia kēia mau lymphoma i ʻelua ʻano nui:
Ke kamaʻilio kāu kauka e pili ana i kēia maʻi, hiki iā ia ke hoʻohana i ʻelua mau huaʻōlelo: "aggressive" a me "indolent." Eia ke ʻano o lākou:
- ʻAno hoʻouka kaua (laha wikiwiki): Ulu wikiwiki kēia ʻano a hiki ke laha (metastasize) i nā ʻōpū ʻē aʻe ma waho o ke kino ma o ka ʻōnaehana lymphatic.
- ʻAno palupalu (ulu lohi): Ulu lohi loa kēia ʻano a ʻaʻole paha e hōʻike i nā hōʻailona no nā makahiki.
I mea e maʻalahi ai ka hoʻomaopopo ʻana, e nānā kākou i kēia mau ʻano ma kahi papa e like me kēia.
| ʻAno o ka lymphoma | Ka wehewehe maʻalahi a me nā laʻana |
|---|---|
| Hoʻouka kaua (hoʻolaha koke) | Ulu koke kēia mau mea. Nā Laʻana:
|
| Palaualelo (ulu lohi) | Hiki i kēia mau mea ke lilo i asymptomatic no nā mahina a i ʻole nā makahiki. Nā Laʻana:
|
He aha nā hōʻailona o ka lymphoma B-cell?
I kekahi manawa hiki iā ʻoe ke loaʻa i ka lymphoma B-cell me ka ʻole o nā hōʻailona. ʻOi loa i nā ʻano ulu lohi, ʻike pinepine ʻia ia i ka wā o nā hoʻokolohua no kekahi maʻi ʻē aʻe. Eia nō naʻe, pono ʻoe e hopohopo inā loaʻa iā ʻoe kēia mau hōʻailona:
| Hōʻailona | He aha ke ʻano o kēia? |
|---|---|
| Nā ʻōpū lymph pehu | Nā puʻupuʻu ʻeha ʻole ma ka ʻāʻī, nā ʻāʻī lima, a me ka ʻūhā. ʻO kēia ka hōʻailona maʻamau. |
| Ka hou nui ʻana i ka pō | E hou ana i ka hou ke pulu kou mau lole moe a me nā pepa moe. |
| Kuni me ke kumu ʻole | He kuni (ma luna o 38 Celsius / 100.4 Fahrenheit) e mau ana no nā lā ʻelua a ʻoi aku paha. |
| ʻO ka pohō kaumaha me ke kumu ʻole | Ka pohō kaumaha koke me ka ʻole o ka ʻai ʻana a i ʻole ka hoʻoikaika kino ʻana. |
| Luhi mau | Manaʻo nāwaliwali ʻoe me ka nānā ʻole i ka nui o kou hoʻomaha ʻana. ʻO ke kumu nui paha o kēia , ʻo ia ka hōʻemi ʻana o nā hunaola maʻi ʻaʻai i loko o ka iwi iwi i ka hana ʻana o nā hunaola koko ʻulaʻula, e hoʻoulu ai i ka anemia. |
| ʻEha ʻōpū | Hiki i kekahi mau ʻano ke hoʻoulu i ka ʻeha ʻōpū mau no ka mea hoʻomaka lākou i loko o ka ʻōpū. |
| Makemake nui | Inā pehu ka ʻōpū, hiki iā ia ke paʻi i nā ʻōpū a hoʻomāʻona iā ʻoe ma hope o ka ʻai iki ʻana. |
| ʻO ka maneʻo (Pruritus) a i ʻole nā loli o ka ʻili | Hoʻomaka kekahi mau ʻano ma ka ʻili a hiki ke hana i nā ʻulaʻula, nā paila, a me nā puʻupuʻu. A i ʻole, inā pilikia ke akepaʻa, hiki i ka ʻili ke ʻānai. |
E hoʻomanaʻo, ʻo ka loaʻa ʻana o hoʻokahi a ʻoi aku paha o kēia mau hōʻailona ʻaʻole ia he manaʻo he lymphoma kou. Hiki i ke anu maʻamau ke hana i ka ʻeha ʻāʻī. Akā inā hoʻomau a ʻoi aku paha ka ʻino o kēia mau hōʻailona, e ʻike pono i kāu kauka no ka ʻōlelo aʻo.
No ke aha lā e hana ʻia ai kekahi mea e like me kēia?
He mea paʻakikī ke kuhikuhi i hoʻokahi kumu no kēia. ʻO ka mea nui, ʻo ka lilo ʻana o kā mākou mau cell-B i maʻi kanesa ma muli o kahi loli genetic (mutation) e hana ʻia i ka wā e māhele ai lākou. Eia nō naʻe, ua ʻike ʻia e ka noiʻi e hoʻonui iki paha kekahi mau mea i ka pilikia o ka hoʻomohala ʻana i kēia.
- ʻO kekahi mau maʻi autoimmune: No ka laʻana, nā poʻe me nā maʻi e like me ka rheumatoid arthritis a me ka maʻi Sjörgren.
- ʻO kekahi mau maʻi viral: Ka ʻike ʻia ʻana i nā maʻi e like me ka HIV (human immunodeficiency virus), ka maʻi Epstein-Barr.
- Moʻolelo ʻohana: Inā ua loaʻa kekahi o ka ʻohana i ka maʻi kanesa e like me Hodgkin lymphoma.
- Momona: ʻO ke kaumaha o ke kino kekahi mea pilikia.
Pehea ʻoe e ʻike ai i kēia, e Kauka?
Ke hele ʻoe i ke kauka, e nīnau ʻo ia e pili ana i kāu mau hōʻailona a me kou mōʻaukala olakino. A laila e hana ʻo ia i kahi hoʻokolokolo kino a nānā i kou mau lymph nodes, ate, a me ka spleen no ka pehu ʻana. Inā he kānalua, e kuhikuhi ʻo ia iā ʻoe i kahi hematologist-oncologist. Hiki ke hana ʻia kēia mau hoʻokolohua e hōʻoia i ka hōʻailona.
Nā hoʻāʻo koko
- Helu koko piha (CBC): Ana i nā ʻano a me ka nui o nā cell i loko o ke koko.
- Panel metabolic piha (CMP): Nānā i ka hana o nā ʻōpū e like me ke akepaʻa a me nā puʻupaʻa.
- Lactate dehydrogenase (LDH): ʻO nā pae kiʻekiʻe o kēia mea he hōʻailona ia o ka lymphoma.
Nā hoʻokolohua kiʻi
- Nā scan CT, nā scan PET, a me nā scan ultrasound: Hiki i kēia ke nānā i ke kūlana o nā lymph node a me nā ʻōpū i loko o ke kino.
Biopsy
ʻO kēia wale nō ke ala e hōʻoia ai i ka maʻi 100%.
ʻO kēia ke kumu o ka lawe ʻana i kahi hāpana liʻiliʻi o kahi lymph node pehu a i ʻole nā ʻiʻo kānalua a nānā iā ia ma lalo o kahi microscope. Hiki i kēia ke kōkua i ka hoʻoholo ʻana i ke ʻano kikoʻī o ka lymphoma.
- Biopsy excisional a incisional paha: Wehe ʻana i kahi ʻāpana a i ʻole kahi kiko lymph i ke ʻano hana ʻoki kino.
- ʻO ka huki ʻana i ka nila maikaʻi (FNA): Ke loaʻa ʻana o kahi liʻiliʻi o nā cell me ka hoʻohana ʻana i kahi nila lahilahi.
- Biopsy iwi ʻiʻo: Ke lawe ʻana i kahi hāpana liʻiliʻi o ka iwi ʻiʻo no ka hoʻokolokolo ʻana.
He aha nā lāʻau lapaʻau?
ʻAʻohe lāʻau lapaʻau hoʻokahi e kūpono i nā mea āpau no kēia. ʻO ka lāʻau lapaʻau āu e loaʻa ai e hilinaʻi ʻia i nā mea e like me ke ʻano o ka lymphoma āu i loaʻa ai, pehea ka mamao o ka laha ʻana o ka maʻi, a me kou olakino holoʻokoʻa. E koho kāu hui lapaʻau i ka hoʻolālā lapaʻau kūpono loa iā ʻoe a he liʻiliʻi loa nā hopena ʻaoʻao.
ʻO nā ʻano lapaʻau nui:
- Chemotherapy: Ke hāʻawi ʻana i nā lāʻau lapaʻau e pepehi i nā hunaola kanesa.
- Immunotherapy: Hoʻoulu i kāu ʻōnaehana palekana ponoʻī e hakakā i nā hunaola kanesa.
- Lapaʻau radiation: Ke luku ʻana i nā hunaola kanesa me ka hoʻohana ʻana i nā kukuna ikehu kiʻekiʻe.
- Lapaʻau i kuhikuhi ʻia: Ke hāʻawi ʻana i nā lāʻau lapaʻau e kuhikuhi a hoʻouka wale i nā hunaola kanesa. Eia kekahi laʻana: `(monoclonal antibody therapy)`.
- Ke kali makaʻala / kiaʻi ʻana: No nā ʻano ulu lohi, e nānā mau ʻia kou kūlana, me ka hoʻomaka koke ʻole ʻana i ka lāʻau lapaʻau inā ʻaʻohe ou hōʻailona. Hoʻomaka wale ʻia ka lāʻau lapaʻau inā loaʻa nā hōʻailona.
Nā hopena ʻaoʻao o ka lāʻau lapaʻau
Hiki i nā lāʻau lapaʻau āpau ke loaʻa nā hopena ʻaoʻao. ʻO nā mea e like me ka ʻeha o ka ʻōpū, ka maʻi kahe, ka luhi, ka nausea, a me ka luaʻi ʻana he mea maʻamau. Mai makaʻu i kēia mau mea. E kamaʻilio me kāu kauka e pili ana iā lākou me ka wehe. Aia nā lāʻau lapaʻau e kōkua i ka hoʻokele ʻana i nā hopena ʻaoʻao.
I ka manawa hea e ʻike ai i ke kauka a i ka manawa hea e hele ai i ka ETU
Pono ʻoe e ʻike pinepine i kāu kauka i kou wā lapaʻau. Ma hope o ka pau ʻana o ka lapaʻau, e nānā ʻia ʻoe ma kahi papa hana maʻamau e ʻike ai inā ua hoʻi mai ka maʻi.
Eia nō naʻe, i kēlā hihia , e hele koke i ka Emergency Treatment Unit (ETU) o ka haukapila:
- Inā ʻoi aku ke kiʻekiʻe o kou kuni ma mua o 38 Celsius (100.4 Fahrenheit) a ʻaʻole i iho i lalo, ʻo ia ke kumu e hoʻonāwaliwali ai ka lāʻau i kou ʻōnaehana pale a alakaʻi i nā maʻi.
- Inā ʻoi aku ka koʻikoʻi o nā hopena ʻaoʻao o ka lāʻau lapaʻau e hiki ʻole ke kaohi ʻia me ka lāʻau lapaʻau i kauoha ʻia e ke kauka.
Leka Lawe-Home
- ʻO ka lymphoma B-cell kahi ʻano maʻi koko e hoʻomaka ana i loko o nā B-cell o kā mākou ʻōnaehana pale.
- ʻO nā hōʻailona nui he mau puʻupuʻu ʻeha ʻole ma ka ʻāʻī, nā ʻūpā lima, a i ʻole ka ʻūhā, ka hou nui ʻana i ka pō, ka luhi mau, a me ka pohō kaumaha i wehewehe ʻole ʻia.
- Inā hoʻomau kēia mau hōʻailona, mai hoʻowahāwahā iā lākou a e ʻike pono i ke kauka.
- Nui nā lāʻau lapaʻau kūpono no kēia maʻi i kēia lā, no laila mai hoʻopau i ka manaʻolana ke ʻike ʻia ʻoe.
- ʻAʻole pono ʻoe e hele hoʻokahi ma kēia huakaʻi. E kiʻi i ke kākoʻo mai kāu hui lapaʻau, ʻohana, a me nā hoaaloha. He mea nui kou olakino noʻonoʻo e like me kou olakino kino.
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