Loaʻa i kāu pēpē nā wahi kofe-au-lait? E kamaʻilio kākou e pili ana i kēia mau wahi Café-au-Lait!

Ua ʻike anei ʻoe i nā kiko ʻeleʻele māmā ma ka ʻili o kāu keiki liʻiliʻi, a i ʻole kou ʻili ponoʻī paha, e like me ke kala o ke kofe me ka waiū? Hopohopo iki kekahi mau makuahine ke ʻike lākou i kēia mau mea. Akā, ʻaʻole nā ​​kiko āpau he mea weliweli. I kēia lā, e kamaʻilio kākou e pili ana i kēia mau mea i kapa ʻia ʻo nā kiko Café-au-Lait. E ʻike pono kākou i ke ʻano o lākou, no ke aha lākou e kū mai ai, a inā he mea weliweli paha lākou a ʻaʻole paha.

He aha kēia mau wahi ʻo Café-au-Lait?

I ka ʻōlelo maʻalahi, ʻo nā kiko Café-au-Lait kahi ʻano hānau pigmented e kū ana ma ka ʻili. ʻO "Café-au-Lait" kahi huaʻōlelo Farani ʻo ia hoʻi "kofe me ka waiū." No laila, hiki ke ʻokoʻa ke kala o kēia mau kiko mai ka ʻeleʻele māmā a i ka ʻeleʻele ʻeleʻele, e like me ke kofe me ka waiū. ʻOkoʻa ke ʻano o kēia kala mai ke koena o kou ʻili.

Hiki i kēia mau kiko ke ʻokoʻa ka nui mai kekahi mau milimita a ʻoi aku ma mua o 20 kenimika. Loaʻa pinepine lākou ma ka ʻili o nā pēpē i ka wā hānau a i ʻike ʻia paha i ka wā kamaliʻi. Eia nō naʻe, i kekahi manawa hiki i kēia mau kiko ke ulu i loko o nā pākeke. ʻAʻole lākou he mau puʻupuʻu i hoʻāla ʻia ma ka ʻili, akā ua like me ka ʻili.

Aia kekahi mau ʻano o kēia mau kiko?

ʻAe, ua māhele nui ʻia kēia mau wahi Café-au-Lait i ʻelua ʻano ma muli o ko lākou ʻano a me ke ʻano. He mea ʻē paha kēia mau inoa, akā aia ke kumu no lākou.

1. ʻAno "Kahakai o Kaleponi": ʻO kēia ke ʻano maʻamau. E like me ke kahakai ma ka palapala ʻāina o ka mokuʻāina ʻo Kaleponi ma ʻAmelika Hui Pū ʻIa, he mau lihi maopopo a laumania kēia mau wahi. Aia paha he wahi hoʻokahi a i ʻole kekahi mau wahi me nā lihi maopopo.

2. ʻAno "Kahakai o Maine": He ʻano maʻamau iki kēia. E like me ke kahakai o Maine ma ʻAmelika Hui Pū ʻIa, he ʻoʻoleʻa a ʻāwili iki nā lihi o kēia mau wahi.

ʻO ka mea nui , inā he ʻoi aku ma mua o ʻeono mau kiko "Coast of California" ma kou ʻili, he mea nui e ʻimi i ke kōkua lapaʻau. No ka mea, ʻo ka loaʻa ʻana o nā kiko he nui i kekahi manawa he hōʻailona ia o kahi maʻi ma lalo, e like me ke ʻano genetic e like me Neurofibromatosis type 1 (NF1) . ʻO kēia nā maʻi e hoʻopilikia ai i ka ʻili a me ka ʻōnaehana nerve.

ʻO wai ka mea i loaʻa pinepine i kēia mau kiko? Pehea ka maʻamau?

Hiki i nā kiko Café-au-Lait ke loaʻa i kekahi. He mea hānau pinepine lākou, ʻo ia hoʻi, aia lākou i ka wā hānau. Eia naʻe, ʻaʻole paha lākou e ʻike nui ʻia ma ka ʻili o kahi pēpē hānau hou. I ko lākou ʻelemakule ʻana, ʻoiai ma hope o ʻelua makahiki, ʻike nui ʻia lākou.

ʻOiai ʻoi aku ka maʻamau o kēia mau kiko i waena o ka poʻe me nā ʻili ʻeleʻele, hiki iā lākou ke loaʻa i kekahi me kekahi kala ʻili.

Ua pili kekahi mau wahi café-au-lait i nā kūlana genetic. ʻO ke ʻano kēia, inā loaʻa i kekahi o kou ʻohana ke kūlana, he ʻano hoʻoilina paha ia. Inā ʻoe e hoʻolālā ana e loaʻa nā keiki, he mea nui e ʻike inā he kūlana genetic i loko o kou ʻohana. Hiki iā ʻoe ke kamaʻilio me ke kauka e aʻo hou e pili ana i kēia a nīnau e pili ana i ka hoʻāʻo genetic .

He mea maʻamau kēia mau wahi a ua manaʻo ʻia aia ma kahi o 10% o ka heluna kanaka ma ka liʻiliʻi he wahi Café-au-Lait hoʻokahi.

Eia kekahi, 95% o ka poʻe me ka neurofibromatosis type 1 (NF1) he ʻoi aku ma mua o ʻeono mau wahi café-au-lait.

Ke hoʻopilikia nei anei nā wahi Café-au-Lait i ka pēpē ma kekahi ʻano?

ʻO ka hapa nui o ka manawa, he mau kiko wale nō nā kiko o Café-au-Lait. ʻAʻole lākou he maʻi kanesa (benign), ʻo ia hoʻi, ʻaʻole lākou he mea weliweli, a ʻaʻole lākou e hōʻeha i ke kino o ke keiki. No laila, inā loaʻa iā ʻoe kekahi a ʻelua paha o kēia mau kiko, ʻaʻohe mea e hopohopo ai.

Eia naʻe, e like me kaʻu i ʻōlelo ai ma mua, inā ʻoi aku ma mua o ʻeono (06) o kēia mau kiko ma kou ʻili, pono ʻoe e ʻike i kahi kauka keiki a kauka ʻili paha. I ka piʻi ʻana o ka nui o nā kiko, he hōʻailona paha ia o kekahi maʻi hoʻoilina ʻē aʻe.

Pehea ke ʻano o kēia mau kiko?

Aia kekahi mau ʻano e hiki ke kōkua iā ʻoe e hoʻokaʻawale i nā wahi café-au-lait mai nā māka hānau ʻē aʻe. E nānā kākou i ke ʻano o lākou:

• Nā kiko pālahalaha: ʻAʻole i hoʻāla ʻia kēia mau mea e like me nā puʻupuʻu. Loaʻa pinepine lākou ma ke kino, nā lima, nā wāwae, a me nā puʻupuʻu.
• He waihoʻoluʻu mai ka ʻeleʻele māmā a i ka ʻeleʻele ʻeleʻele: e like me ke kala o ke kofe me ka waiū.
• ʻAno poepoe a ʻōvalo paha: Hiki i ka nui ke piʻi mai 2 millimeters (mm) a ʻoi aku ma mua o 20 kenimika (cm).
• He ʻaoʻao laumania a ʻāʻī paha a puni kahi: e like me ke "kahakai Kaleponi" a i ʻole "kahakai ʻo Maine" a mākou i kamaʻilio ai.
• Hiki ke hoʻonui ʻia ka nui a me ka helu o nā kiko me ka makahiki.
• ʻAʻole kēia mau kiko e hoʻoulu i ka ʻeha, ka maneʻo, a i ʻole nā ​​​​hōʻailona ʻē aʻe.

No ke aha e ʻike ʻia ai kēia mau wahi Café-au-Lait? He aha ke kumu?

ʻO ke kumu nui o ka hoʻokumu ʻia ʻana o kēia mau kiko, ʻo ia ka hoʻonui ʻia ʻana o ka helu o nā melanocytes, kahi ʻano cell e hāʻawi i ke kala i ka ʻili, ma ka papa waho lahilahi o ko mākou ʻili, ka ʻāpana i kapa ʻia ʻo epidermis. Hoʻopuka kēia mau melanocytes i ka pigment melanin . Hāʻawi kēia melanin i ke kala i ko mākou ʻili, nā maka, a me ka lauoho, a pale pū i ka ʻili mai ka lā. No laila, inā hōʻiliʻili koke ka nui o kēia mau cell melanocyte ma kahi kikoʻī, hoʻonui pū ka hana ʻana o ka melanin, a lilo ke kala o ka ʻili ma ia wahi i ʻeleʻele ʻeleʻele. ʻO ia ka Café-au-Lait spot.

Eia nō naʻe, ʻaʻole i loaʻa kahi kumu maopopo no ke kumu e hōʻiliʻili pinepine ai kēia mau pūnaewele melanocyte i nā helu nui ma kahi hoʻokahi.

Eia nō naʻe, ʻo ka neurofibromatosis ʻano 1 (NF1)Hoʻokumu ʻia nā kiko Café-au-Lait e kahi mutation i loko o kahi gene i kapa ʻia ʻo ka gene NF1 . Hoʻomalu ka gene NF1 i ka wikiwiki o ka ulu ʻana o nā cell. No laila, ke hoʻololi ʻia kēia gene, ulu nā cell melanocyte me ke kāohi ʻole ʻia a hana i ka melanin nui loa i loko o ka ʻili.

I kekahi manawa, hiki ke hana ʻia ka mutation gene NF1 me ka ʻole o kekahi o ka ʻohana i loaʻa. I nā manawa ʻē aʻe, inā loaʻa i kekahi o nā mākua ka mutated NF1 gene, hiki i ke keiki ke hoʻoilina i ke kūlana. Ua kapa ʻia kēia he autosomal dominant inheritance . Eia naʻe, ʻaʻole e like me nā kūlana autosomal dominant ʻē aʻe, no ka ulu piha ʻana o NF1, pono e hana ʻia kahi mutation ma ka kope ʻelua o ka gene NF1 i ka wā o ke ola o ke kanaka. He mea paʻakikī iki kēia, no laila ʻoi aku ka maikaʻi o ke noi ʻana i ke kauka no ka ʻike hou aku.

Pehea e ʻike ai ke kauka i kēia mau kiko?

Ma hope o ka hānau ʻana o kāu pēpē, e hana ke kauka i kahi nānā piha ma kāu pēpē, ʻeā? I kēlā manawa, e ʻike ke kauka i nā māka hānau ma ka ʻili o kāu pēpē, me nā kiko Café-au-Lait. E aʻo pū ʻo ia iā ʻoe e nānā i ka nui o kēia mau kiko i loaʻa i kāu pēpē i kona wā e ulu ana.

ʻAʻole paha e ʻike piha ʻia kēia mau kiko ma ka ʻili o kahi pēpē hānau hou, akā i ka wā e piha ai ke pēpē i ʻelua makahiki, a i ʻole ma hope o ka hōʻike ʻana i ka lā, e ʻike nui ʻia kēia mau kiko.

Inā he ʻoi aku ma mua o ʻeono mau kiko, he hōʻailona paha ia o kahi maʻi ʻē aʻe?

ʻAe, he mea ia e pono ai kākou e hopohopo nui. ʻO ka loaʻa ʻana o nā wahi Café-au-Lait ma mua o ʻeono (06) hiki ke lilo i hōʻailona o kekahi mau kūlana genetic. ʻO kekahi o kēia mau kūlana:

• ʻAno Neurofibromatosis 1 (NF1)
• ʻO ka maʻi McCune-Albright
• ʻO ka maʻi Noonan
• ʻO ka maʻi Watson

No laila, inā ʻike ʻoe ma mua o ʻeono mau kiko Café-au-Lait ma ka ʻili o kāu keiki, mai hoʻonele i ka manawa a e ʻike koke i ke kauka o kāu keiki. Hiki iā ia ke nānā i nā kiko a kuhikuhi iā ʻoe no ka hoʻāʻo hou aku inā pono.

Aia kekahi lāʻau lapaʻau no kēia mau wahi Café-au-Lait?

ʻAʻole maʻi kanesa (benign) nā kiko Café-au-Lait, ʻo ia hoʻi, ʻaʻole lākou e pōʻino, no laila ʻaʻole pono lākou e mālama ʻia. ʻAʻole lākou e hōʻike i kekahi mau hōʻailona.

Eia nō naʻe, makemake paha kekahi poʻe e wehe i kēia mau kiko no nā kumu hoʻonaninani, ʻo ia hoʻi, e nānā maikaʻi aʻe. I kēlā hihia, hiki iā ʻoe ke kamaʻilio me kāu kauka e pili ana i ka mālama ʻana me ka laser . Eia nō naʻe, aia kekahi mau pilikia i ka wā e wehe ai i nā kiko me ka mālama ʻana me ka laser. No ka laʻana, hiki ke lilo ke kala o ka ʻili i ʻeleʻele ma ka wahi i mālama ʻia (hyperpigmentation)., hiki ke hana ʻia nā ʻōpala, ʻaʻole paha e nalo loa ke kala o ke kiko, a i ʻole e ʻike hou ʻia ke kiko ma hope o ka wehe ʻana.

Aia kekahi ala e hōʻemi ai i ka hanana o kēia mau kiko ma nā pēpē?

ʻOiaʻiʻo, ʻaʻohe ala e pale aku ai i ke kūkulu ʻia ʻana o nā kiko Café-au-Lait, no ka mea, ʻaʻole hiki iā mākou ke pale aku i ke kūkulu ʻia ʻana o nā māka hānau.

Eia nō naʻe, inā loaʻa i kekahi o kou ʻohana kahi maʻi genetic e like me ka neurofibromatosis type 1 (NF1) , ʻo ke kamaʻilio ʻana me ke kauka e pili ana i ka hoʻāʻo genetic ma mua o kou hoʻolālā ʻana e hāpai hiki ke kōkua iā ʻoe e hoʻomaopopo i kou pilikia o ka loaʻa ʻana o kahi keiki me kēlā ʻano.

Inā loaʻa kēia mau kiko i kaʻu pēpē, he aha kaʻu e manaʻo ai?

Loaʻa nā kiko Café-au-Lait mai ka wā hānau. Hiki iā lākou ke noho i loko o ke ola o ke keiki. Hiki ke loli iki ka nui a me ke ʻano o kēia mau kiko i ka hala ʻana o ka manawa. Eia kekahi, hiki ke ʻike nui ʻia kēia mau kiko ke hōʻike ʻia i ka lā.

ʻO ka mea nui loa, ʻo ia ke ʻimi i ke kōkua lapaʻau inā ʻike ʻoe ma mua o ʻeono o kēia mau kiko ma ka ʻili o kāu keiki e ʻike ai inā he hōʻailona ia o kekahi maʻi olakino ʻē aʻe.

Āhea ʻoe e pono ai e ʻike i ke kauka?

Inā ʻike ʻoe i kekahi mau loli i nā kiko Café-au-Lait o kāu keiki, no ka laʻana , inā pehu nā kiko, piʻi aʻe, ʻike ʻia he puʻupuʻu ke hoʻopā ʻia, a inā piʻi koke ka nui a i ʻole ka helu o nā kiko, e ʻike koke i ke kauka.

He mea maʻamau ka loaʻa ʻana o kekahi mau kiko café-au-lait. Eia nō naʻe, ʻo ka loaʻa ʻana o nā kiko ma mua o ʻeono he hōʻailona paha ia o kahi maʻi maʻi. Eia kekahi mau hōʻailona ʻē aʻe e pili ana i nā maʻi maʻamau e hoʻoulu ai i nā kiko café-au-lait:

• Nā pilikia ʻōlelo a me ka ʻōlelo.
• Nā puʻupuʻu ma lalo o ka ʻili ʻaʻole he maʻi ʻaʻai (neurofibromas) .
• Nā kiko ma lalo o nā ʻauwae.
• Ke koko kiʻekiʻe (hypertension) .
• Nā pilikia ulu iwi, no ka laʻana , scoliosis .
• Ka maʻi hoʻolohe-nele/hyperactivity (ADHD) .

Inā loaʻa i kāu keiki nā hōʻailona ʻē aʻe e like me kēia me ka nui o nā wahi Café-au-Lait, e hoʻomaopopo i ke kauka e pili ana i kēlā.

He aha nā nīnau koʻikoʻi e nīnau aku ai i ke kauka?

Ke hele ʻoe e ʻike i ke kauka, hiki iā ʻoe ke nīnau i nā nīnau e like me kēia:

• He hōʻailona anei nā wahi café-au-lait o kaʻu keiki no kahi maʻi hoʻoilina?
• Hiki iaʻu ke hana i kahi hoʻokolohua genetic e loiloi i koʻu pilikia o ka loaʻa ʻana o kahi keiki me kahi maʻi genetic?
• He aha kaʻu e hana ai inā ʻike au ma mua o ʻeono mau kiko Café-au-Lait ma ka ʻili o kaʻu keiki?

Hiki ke ʻike koke ʻia nā kiko Café-au-Lait ma hope o ka wā makua?

ʻAe, hiki ke hana. ʻOiai he pinepine nā kiko café-au-lait ma ka ʻili o nā pēpē hānau hou, he mea maʻamau nō hoʻi ka ulu ʻana o kēia mau kiko ma ka ʻili o kekahi ma hope o ke ola. He mea maʻamau no kekahi ke loaʻa i kekahi mau kiko café-au-lait. Eia nō naʻe, inā he ʻoi aku kou mau kiko ma mua o ʻeono, he hōʻailona paha ia o kahi maʻi ma lalo. No laila, me ka nānā ʻole i kou mau makahiki, inā ʻike ʻoe ma mua o ʻeono mau kiko café-au-lait ma kou ʻili, e ʻike i ke kauka e nānā iā lākou.

Hiki ke loaʻa kēia mau kiko me ka ʻole o ka neurofibromatosis?

ʻAe, ʻoiaʻiʻo nō. He mea maʻamau loa i nā kānaka ke loaʻa kekahi mau kiko café-au-lait ma ko lākou kino me ka ʻole o kahi maʻi kumu, e like me ka neurofibromatosis type 1 (NF1) . ʻO ka poʻe me NF1 he ʻoi aku ma mua o ʻeono mau kiko café-au-lait, a hōʻike pū lākou i nā hōʻailona ʻē aʻe e kūlike me ka hōʻailona.

Ua like anei kēia mau kiko me ka ʻulaʻula o ka ʻili?

ʻAʻole. ʻOiai ke ʻano o kēia mau kiko e like me ka ʻulaʻula, ʻaʻole i hoʻokumu ʻia nā kiko Café-au-Lait e kahi hopena maʻi. He poni a ʻulaʻula paha ka ʻulaʻula, ʻeā? Akā, ʻokoʻa ke kala o nā kiko Café-au-Lait mai ka ʻeleʻele māmā a i ka ʻeleʻele ʻeleʻele. Eia kekahi, ʻoiai hiki i ka ʻulaʻula ke hoʻoulu i nā hōʻailona e like me ka maneʻo, ʻaʻole hoʻoulu nā kiko Café-au-Lait i ka maneʻo a i ʻole ka ʻoluʻolu ʻole.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai

ʻO nā kiko Café-au-Lait kahi ʻano hōʻailona hānau e hiki ke ʻike ʻia ma ka ʻili o kāu keiki, a pinepine ʻaʻole ia he mea ʻino. ʻOiai ʻaʻole lākou he mea weliweli, he mea nui e mālama i ka nui o kēia mau kiko i loaʻa i kāu keiki. ʻOi aku ma mua o ʻeono mau kiko he hōʻailona paha ia o kahi maʻi maʻi. Inā ʻike ʻoe i kekahi mau loli i nā hōʻailona hānau o kāu keiki, e ʻimi koke i ke kōkua lapaʻau. Mai hopohopo, ʻo ka ʻike ka mea nui!

`Nā kiko Café-au-Lait, nā kiko ʻili, nā māka hānau, nā kiko ʻeleʻele, ke olakino o nā keiki, nā maʻi hoʻoilina, neurofibromatosis, Neurofibromatosis