He pilikia olakino ka maʻi diabetes a nā kānaka he nui o ko kākou kaiāulu e kū nei i kēia lā. ʻO ka mea nui, hiki ke loaʻa ka maʻi diabetes Type 2 i kēlā me kēia makahiki. Me kēia kūlana, piʻi pū ka pilikia o ka loaʻa ʻana o kekahi mau pilikia olakino ʻē aʻe. No laila, he nui nā ʻano lāʻau lapaʻau a nā kauka e ʻōlelo ai e kāohi i kēia maʻi diabetes. ʻO kekahi o ia mau lāʻau lapaʻau ʻo Farxiga. I kēia lā, ma kēia ʻatikala, e kamaʻilio mākou e pili ana i nā mea nui e pono ai ʻoe e ʻike inā kuhikuhi kāu kauka i kēia lāʻau lapaʻau nāu.
Pehea e hana ai ʻo Farxiga i loko o ke kino?
ʻO kēia lāʻau lapaʻau, nona ka inoa inoa ʻo Farxiga, aia ka mea hana nui ʻo dapagliflozin . No kēia mau mea kahi papa o nā lāʻau lapaʻau i kapa ʻia ʻo SGLT2 inhibitors. I kēia manawa e nānā kākou i kēia ma nā ʻōlelo maʻalahi.
E noʻonoʻo i ko kākou mau puʻupaʻa e like me ʻelua mau kānana nui. Hoʻomaʻemaʻe kēia mau kānana i ko kākou koko a wehe i nā mea makemake ʻole ʻia ma o ka mimi. Ma kēia ʻano, kānana ʻia ke kō (glucose) i loko o ke koko i loko o ka mimi. Akā, he maalea loa ko kākou kino. Ma ka hoʻohana ʻana i kahi protein i kapa ʻia ʻo SGLT2 i loko o nā puʻupaʻa, hoʻopili hou ia i ke kō e hoʻāʻo nei e komo i loko o ka mimi. Loaʻa i ke kanaka me ka maʻi diabetes nā pae kō kiʻekiʻe i loko o ko lākou kino. No laila, ʻaʻole maikaʻi ka hoʻopili hou ʻana i ke kō.
Hana ʻo Farxiga ma ke ālai ʻana i ka hana o ka protein SGLT2 . ʻO ke ʻano kēia, ʻaʻole i komo hou ke kō i loko o ke kino, akā ua hoʻokuʻu ʻia i loko o ka mimi. I ka ʻōlelo maʻalahi, ʻo ka hana nui o kēia lāʻau lapaʻau ka hoʻomalu ʻana i nā pae kō koko ma ka wehe ʻana i ke kō keu mai kou kino ma o ka mimi .
He aha nā hopena o kēia lāʻau lapaʻau?
Ua aʻo nui ʻia ʻo Farxiga a puni ka honua. Ua ʻike ʻia kēia mau haʻawina he mea kūpono loa ia i ka hoʻohaʻahaʻa ʻana i nā pae kō koko, i ka wā e hoʻohana wale ʻia ai a i hui pū ʻia me nā lāʻau lapaʻau maʻi diabetes ʻē aʻe.
Ua hoʻohana ʻia ʻo Farxiga me nā lāʻau lapaʻau e hiki mai ana i hoʻohana pinepine ʻia e mālama i ka maʻi diabetes:
- Metformin
- nā sulfonylureas (e.g. Gliclazide, Glimepiride)
- Nā agonists receptor GLP-1
- ʻInisulina
- Nā mea hoʻopaʻa DPP-4
- ʻO nā Thiazolidinediones
ʻO ka mea nui e nānā ʻia ana i kēia mau haʻawina he waiwai i kapa ʻia ʻo HbA1c (hemoglobin A1c). I ka ʻōlelo maʻalahi, ʻo HbA1c kou awelika o ke kō koko i nā mahina 2-3 i hala . Ua like ia me kahi 'kāleka hōʻike' o kāu kaohi ʻana i ka maʻi diabetes. I loko o nā haʻawina he nui, ʻo ka poʻe i hoʻohana iā Farxiga he haʻahaʻa loa ko lākou mau pae HbA1c.
ʻEhia ka lōʻihi e ʻike ai i nā hopena?
E hoʻomaka ana kou pae kō koko e hāʻule koke ma hope o kou hoʻomaka ʻana e lawe iā Farxiga. Inā ʻoe kekahi e nānā i kāu kō koko ma ka home, e ʻike ʻoe i kahi ʻokoʻa nui i loko o nā pule 4 mua.Hiki iā ʻoe ke ʻike. Akā, he manawa iki ka emi ʻana o ka waiwai HbA1c. No ka mea, he awelika o 2-3 mahina ia, hiki ke hala ma kahi o 8 a 12 mau pule e ʻike ai i kahi loli o kēlā waiwai.
Aia kekahi mau pono ʻē aʻe ma waho aʻe o ka hoʻēmi ʻana i ke kō?
ʻAe! ʻOiai ʻo ka hana nui o Farxiga ka kaohi ʻana i ke kō koko, ua hōʻike ʻia e ka noiʻi he nui nā pono hou aʻe. He mea nui loa kēia no kekahi kanaka me ka maʻi diabetes.
| Pōmaikaʻi hou aʻe | He wehewehe maʻalahi |
|---|---|
| Ka emi ʻana o ke kaumaha | ʻAʻole kēia he pila hoʻemi kaumaha. Eia nō naʻe, ʻoiai ua hoʻokuʻu ʻia ke kō i loko o ka mimi, ua hoʻopau ʻia nā calorie i loko o kēlā kō mai ke kino. No laila, ua ʻike ʻia ʻo ka poʻe e lawe ana i kēia pila e nalowale ana ma kahi o 1.5 - 3.5 kg (3.5 - 7 paona). |
| Ka emi ʻana o ke koko | ʻAʻole kēia he lāʻau lapaʻau no ke koko kiʻekiʻe. Akā, i ka wā e hoʻokuʻu ʻia ai ke kō i loko o ka mimi, e hoʻokuʻu ʻia aku ana kekahi wai mai ke kino mai. Hoʻemi iki kēia i ke koko kiʻekiʻe. |
| Hoʻemi i nā haukapila ma muli o ka maʻi puʻuwai | Ua hōʻike ʻia kēia lāʻau lapaʻau e hōʻemi i ka pilikia o ka hoʻokipa ʻia ʻana ma muli o ka hāʻule ʻana o ka puʻuwai inā loaʻa iā ʻoe ka maʻi puʻuwai a i ʻole nā mea pilikia no ia (cholesterol, ke koko kiʻekiʻe, ka puhipaka). |
| Ka palekana o nā puʻupaʻa | Hiki i ka maʻi diabetes ke hōʻino i kou mau puʻupaʻa i ka hala ʻana o ka manawa. Inā loaʻa iā ʻoe ka maʻi puʻupaʻa mau, hiki iā Farxiga ke kōkua i ka pale ʻana i kona ʻino ʻana. |
He aha nā hopena ʻaoʻao o kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki iā Farxiga ke hana i kekahi mau hopena ʻaoʻao liʻiliʻi. He mea nui e makaʻala i kēia mau mea.
1. Nā maʻi hū ʻōpū
ʻO kēia ka hopena ʻaoʻao maʻamau o Farxiga. ʻO ke kiʻekiʻe o ke kō i loko o ka mimi e hana i kahi kūlana maikaʻi no nā fungi e like me ka hū e ulu. ʻOi aku ka maʻamau o kēia i nā wahine.
- Nā Hōʻailona: Ka maneʻo ma ka ʻāpana genital, ka wai kahe ʻala ʻino.
- Pehea e hoʻokele ai?
- E ʻaʻahu i nā lole komo pulupulu.
- E mālama mau i ka ʻāpana genital i maloʻo.
- E kamaʻilio me kāu kauka a e loaʻa iā ʻoe ka lāʻau kūpono.
2. Hypoglycemia - Haʻahaʻa loa ke kō koko
ʻAʻole pinepine kēia ʻano ke lawe wale ʻia ʻo Farxiga. Eia nō naʻe, inā ʻoe e lawe iā Farxiga me ka insulin a i ʻole ka sulfonylurea (e.g., Gliclazide) , e haʻahaʻa loa paha kou pae kō koko.
- Nā hōʻailona: ka hou ʻana, ka haʻalulu, ka pōloli nui, ka poniuniu.
- Hoʻokele: Ke hoʻomaka ʻoe iā Farxiga, pono paha kāu kauka e hoʻohaʻahaʻa i ka nui o kāu mau lāʻau lapaʻau maʻi diabetes ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i kēia.
3. Ketoacidosis Diabetic (DKA)
He maʻi koʻikoʻi kēia akā he mea laha ʻole . Ke hiki ʻole i ke kino ke hoʻohana i ke kō no ka ikehu, puhi ia i ka momona no ka ikehu. I loko o kēia kaʻina hana, hana ʻia nā kemika i kapa ʻia he ketones. Hōʻiliʻili kēia mau mea i loko o ke koko, e lilo ai ke koko i ʻakika, i kapa ʻia ʻo DKA.
- Nā Hōʻailona: Makewai nui, mimi pinepine, ʻeha ʻōpū, nausea, luaʻi, paʻakikī ka hanu ʻana, a me kahi ʻala hua ma ka hanu.
- He aha e hana ai: He pilikia olakino hoʻoweliweli kēia i ke ola. Inā ʻike ʻoe i kekahi a ʻoi aku paha o kēia mau hōʻailona, pono ʻoe e hele koke i ka Emergency Department (ETU) o ka haukapila kokoke loa.
Pehea e hiki ai iaʻu ke loaʻa iā Farxiga?
ʻAʻole ʻo Farxiga he lāʻau lapaʻau hiki iā ʻoe ke kūʻai wale ma ke kūʻai aku ma kahi hale kūʻai lāʻau lapaʻau. Pono ia i kahi kauoha mai ke kauka.
E loiloi kāu mea mālama mua a i ʻole kahi endocrinologist i kou olakino a hoʻoholo inā kūpono kēia lāʻau lapaʻau iā ʻoe. Mai hoʻohana i kēia lāʻau lapaʻau a hoʻololi paha i ka nui i kuhikuhi ʻia me ka ʻole o ke kūkākūkā ʻana me ke kauka.
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Farxiga (dapagliflozin) no ka maʻi diabetes type 2. Kōkua ia i ka hoʻomalu ʻana i nā pae kō koko ma ka hoʻopau ʻana i ke kō keu mai ke kino ma o ka mimi.
- Ma waho aʻe o ke kaohi ʻana i ke kō, kōkua pū ia i ka hoʻemi iki ʻana i ke kaumaha o ke kino a me ke koko, e hoʻemi i ka pilikia o ka maʻi puʻuwai, a pale i nā puʻupaʻa.
- He hopena maʻamau ka maʻi hū ma ka ʻāpana genital. He mea nui e mālama i ka maʻemaʻe.
- Aia kahi pilikia o ka hypoglycemia ke lawe pū ʻia me nā lāʻau lapaʻau maʻi diabetes ʻē aʻe e like me ka insulin. E hoʻomaopopo i kāu kauka e pili ana i kēia.
- E makaʻala i nā hōʻailona o kahi maʻi koʻikoʻi i kapa ʻia ʻo DKA. Inā kānalua, e hele koke i ka ʻOihana Pilikia (ETU) o ka haukapila.
- Pono e hoʻohana ʻia kēia lāʻau lapaʻau ma ke ʻōlelo aʻo a ke kauka wale nō .
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