Loaʻa iā ʻoe kēia mau hōʻailona? E aʻo kākou e pili ana i ka maʻi ʻaʻai lolo i kapa ʻia ʻo Glioblastoma (GBM)!

I kekahi manawa, loaʻa koke iā kākou ka ʻeha poʻo, a i ʻole ke manaʻo nei kākou i kahi loli i ko kākou ʻike maka, ʻeā? Malia paha ua nalowale iki ko kākou hoʻomanaʻo. Hiki ke maʻamau kēia mau mea, akā i kekahi manawa hiki ke lilo i mau hōʻailona o kahi maʻi koʻikoʻi. I kēia lā, e kamaʻilio kākou e pili ana i kahi ʻano maʻi ʻaʻai lolo koʻikoʻi he mea nui loa e makaʻala.

He aha ka Glioblastoma (GBM)?

I ka ʻōlelo maʻalahi, ʻo Glioblastoma (GBM) kahi ʻano maʻi ʻaʻai lolo ʻino i ʻike nui ʻia i nā pākeke. E noʻonoʻo, aia nā pūnaewele kūikawā i loko o ko kākou lolo e kōkua i nā pūnaewele nerve e hana pono, i kapa ʻia ʻo 'nā pūnaewele glial'. Ma waena o kēia mau pūnaewele glial, aia kekahi ʻano i kapa ʻia ʻo 'astrocytes'. Mai kēia mau pūnaewele i kapa ʻia ʻo astrocytes e hoʻomaka ai kēia maʻi ʻaʻai glioblastoma.

Ulu a hoʻonui koke kēia mau hunaola kanesa. Hohola lākou e like me nā nāhelehele i loko o ka lolo. ʻOiai he mea kakaikahi, i kekahi manawa hiki i kēia kanesa ke hohola ʻaʻole wale i nā ʻāpana ʻē aʻe o ka lolo, akā i ke kaula kuamoʻo i loko o ko kākou iwi kuamoʻo. ʻO ka ʻoiaʻiʻo, he kanesa koʻikoʻi loa kēia. I kekahi manawa, he koʻikoʻi loa ia a hiki ke alakaʻi i ka make ma lalo o ʻeono mahina inā ʻaʻole mālama ʻia. ʻO ia ke kumu he mea nui e makaʻala i kēia.

He aha nā hōʻailona o Glioblastoma (GBM)?

I kēia manawa, e nānā kākou i nā hōʻailona e ʻike ai kekahi kanaka me Glioblastoma (GBM). Hiki ke ʻokoʻa kēia mau hōʻailona mai kēlā kanaka a kēia kanaka, a ʻokoʻa hoʻi ma muli o ka nui o ka puʻupuʻu a me kona wahi ma ka lolo.

• ʻIke pōwehiwehi a ʻike pālua paha: Manaʻo koke paha ʻoe e ʻoi aku ka ʻino o kou ʻike, a i ʻole manaʻo paha ʻoe e ʻike ana i nā mea i ʻelua.
• ʻEha poʻo pinepine: ʻAʻole ia he ʻeha poʻo maʻamau, akā he ʻeha poʻo i koʻikoʻi iki, mau, a i kekahi manawa ʻoi aku ka ʻino i ke kakahiaka.
• Anorexia: Ka nalowale o ka makemake e ʻai.
• Poho ka hoʻomanaʻo: Ka poina ʻana i nā mea a me ka paʻakikī i ka hoʻomanaʻo ʻana i nā inoa.
• Nā loli i ke ʻano a me ke ʻano o ke kanaka: Nā loli e like me ke ʻano ʻole ma mua, ka hoʻololi ʻana i kou manaʻo, ka huhū koke, a i ʻole ka noho mālie loa.
• Ka nalowale o ke kaulike a me ka mae ʻana o ke kino: Lilo kekahi lima a wāwae paha i mae ʻana, nalowale ke kaulike, a hiki ʻole ke mālama i ke kaulike kūpono i ka wā e hele ana.
• Ka luaʻi a me ka luaʻi: ​​Hiki ke loaʻa ka luaʻi a me ka luaʻi, ʻoiai i ke kakahiaka.
• Nā hopu ʻana: Hiki ke loaʻa kahi hopu ʻana ma ke ʻano i hana ʻole ʻia ma mua.
• Ke kuʻia ʻana i ka wā e ʻōlelo ana: Paʻakikī i ka loaʻa ʻana o nā huaʻōlelo, paʻa ke alelo i ka wā e ʻōlelo ana.
• Nā loli i ke ʻano o ke kino, ke ʻūlū ʻana: Hiki i kekahi mau ʻāpana o ke kino ke ʻūlū a i ʻole e manaʻo paha e nalowale ana nā ʻike āpau.

Hoʻomaka pinepine kēia mau hōʻailona e ʻike koke ʻia.No ka mea, i ka ulu ʻana o kēia puʻupuʻu i loko o ka lolo, kau ia i ke kaomi ma luna o ka lolo, a hiki ke luku ʻia nā ʻiʻo lolo olakino.

No ke aha e ulu ai ʻo Glioblastoma (GBM)?

ʻO kahi nīnau a ka poʻe he nui e nīnau nei, "No ke aha e loaʻa ai kēia mau maʻi?" ʻAʻole ʻike nā kānaka noiʻi i ke kumu pololei o Glioblastoma (GBM). Eia naʻe, e like me nā gliomas ʻē aʻe (nā puʻupuʻu e ulu ana i loko o ka lolo a me ke kaula spinal), manaʻoʻiʻo nā kānaka ʻepekema ua hoʻokumu ʻia ia e nā mutations i loko o kā mākou DNA.

ʻIke ʻoe, aia ka DNA i loko o kā mākou mau genes. Hāʻawi kēia mau genes iā mākou i nā kuhikuhi āpau no ke ʻano o ka ulu ʻana a me ka māhele ʻana o nā cell i loko o ko mākou kino. No laila, i ka wā e loaʻa ai kekahi mau loli (mutations) i loko o kēia DNA, hoʻomaka nā cell e māhele wikiwiki a me ke kāohi ʻole ʻia. Pēlā e hoʻokumu ʻia ai kēia mau cell cancer.

He maʻi hoʻoilina anei kēia?

ʻO kekahi nīnau koʻikoʻi, "He maʻi hoʻoilina anei kēia?" I kekahi manawa hiki iā kākou ke hoʻoilina i nā ʻano like ʻole o ka genetic mai ko kākou mau mākua. Eia nō naʻe, he mea kakaikahi loa ʻo Glioblastoma (GBM). ʻO ka hapa nui o ka manawa, hana ʻia kēia mau loli DNA (nā mutations) i ko kākou ola ʻana, ʻo ia hoʻi, ʻaʻohe o lākou loulou genetic.

ʻO wai ka mea i ʻoi aku ka nui o ka pilikia o ka hoʻomohala ʻana i ka Glioblastoma (GBM)?

ʻOiai hiki i kekahi ke loaʻa i kēia maʻi, ʻoi aku ka nui o ka pilikia o kekahi poʻe.

• Makahiki: ʻO Glioblastoma (GBM) ka mea maʻamau i loaʻa i nā poʻe ma waena o 45 a me 70 mau makahiki. ʻO ka awelika o ka makahiki i ka wā i ʻike ʻia ai he 64 mau makahiki.
• ʻO ka ʻike ʻana i kekahi mau kemika: No ka laʻana, ʻo ka ʻike lōʻihi ʻana i nā mea e like me nā pesticides, petroleum, synthetic rubber, a me ka vinyl chloride hiki ke lilo i mea pilikia.
• ʻO kekahi mau maʻi hoʻoilina, kumu puʻupuʻu: ʻO ka poʻe me nā maʻi hoʻoilina e like me '(Neurofibromatosis)', '(Li-Fraumeni syndrome)', a me '(Turcot syndrome)' e piʻi aʻe ka pilikia o ka loaʻa ʻana o kēia maʻi kanesa.
• Inā ua loaʻa mua iā ʻoe ka radiation therapy i ke poʻo: ʻO ka loaʻa ʻana o ka radiation therapy i ke poʻo no kekahi kumu ʻē aʻe he mea pilikia nō hoʻi ia.

Nā pilikia hiki ke loaʻa o Glioblastoma (GBM)

Hiki iā Glioblastoma (GBM) a me kāna mau lāʻau lapaʻau ke loaʻa nā hopena like ʻole i ka hana o ka lolo.

• Hiki ke loli ke ʻano a me nā pilikia hoʻomanaʻo.
• Pono ka nui o ka poʻe me glioblastoma (GBM) e ho'ōki i ka hana ʻana i nā mea e like me ka hana a me ka hoʻokele kaʻa ʻana.
• Malia paha e pono ai ka mālama manawa piha .
• Hiki i kēia mau loli ke alakaʻi i nā kūlana e like me nā maʻi hopohopo a i ʻole ke kaumaha. No laila, he mea nui e mālama i kou olakino noʻonoʻo.

Pehea e ʻike ai nā kauka iā Glioblastoma (GBM)?

ʻAe, e nānā kākou pehea e ʻike ai ke kauka iā Glioblastoma (GBM).

Ke hele ʻoe e ʻike i ke kauka, e hoʻolohe pono mua ʻo ia i kāu mau hōʻailona a hana i kahi hoʻokolohua neurological. ʻO ke ʻano kēia o ka nānā ʻana i kou ʻike, ka lohe, ke kaulike, a me nā reflexes.

Inā kānalua ʻia kahi puʻupuʻu lolo, hiki ke hana ʻia nā hoʻokolohua aʻe:

• ʻO kahi scan MRI (Magnetic Resonance Imaging) a i ʻole kahi scan CT (Computed Tomography): Lawe kēia i nā kiʻi kikoʻī o ka lolo a nānā i nā mea e like me inā he mau puʻupuʻu, pehea ko lākou nui, a me ko lākou wahi i loko o ka lolo.
• Biopsy: ʻO kēia ka hoʻāʻo hope loa e ʻike ai i ka maʻi. Ma kēia, ua wehe ʻia kahi hāpana liʻiliʻi o ka puʻupuʻu ma ke ʻoki ʻana a nānā ʻia ma lalo o kahi microscope e hoʻoholo ai inā he mau hunaola kanesa a me ke ʻano o ke kanesa.

Nā Papa o Glioblastoma (GBM)

Hoʻokaʻawale nā ​​kauka i nā ʻōpū o ka lolo ma muli o kā lākou ʻano, me ka hoʻohana ʻana i kahi ʻōnaehana māka mai I (hoʻokahi) a i IV (ʻehā).

• Lohi ka ulu ʻana o nā puʻupuʻu Papa I a ʻaʻole ikaika loa.
• ʻO nā puʻupuʻu Papa IV ka ulu wikiwiki loa a me ka hoʻouka kaua loa .
• ʻO nā ʻōhū Glioblastoma (GBM) kahi ʻano ʻōhū ikaika loa no ka papa ʻehā (Papa IV).

Hiki iā Glioblastoma (GBM) ke kumu mua a lua paha:

• GBM Mua: Kū pololei kēia mai nā pūnaewele glial, ʻo ia hoʻi he mea hou a huhū lākou.
• ʻO ka GBM Lua: Kū mai kēia mai nā ʻōpū glial haʻahaʻa ma mua (no ka laʻana, Papa I a i ʻole II) i hoʻololi ʻia i Glioblastoma (GBM) ʻoi aku ka ikaika i ka hala ʻana o ka manawa.

Pehea e mālama ʻia ai ʻo Glioblastoma (GBM)?

I kēia manawa, e nānā kākou i nā lāʻau lapaʻau i loaʻa no kēia. ʻO Glioblastoma (GBM) he maʻi paʻakikī ke ho'ōla loa. Eia nō naʻe, aia nā lāʻau lapaʻau e hiki ke kōkua i ka kaohi ʻana i nā hōʻailona, ​​​​hoʻolōʻihi iki i ke ola, a hoʻomaikaʻi i ke ʻano o ke ola. ʻOkoʻa ka hoʻolālā lapaʻau mai kēlā mea kēia mea maʻi a hoʻoholo ʻia e kahi hui o nā kauka.

ʻO nā ʻano lapaʻau nui:

• ʻOki ʻana: Ke wehe ʻana i ka nui o ka puʻupuʻu e like me ka hiki. I kekahi manawa he mea paʻakikī paha ke wehe i ka puʻupuʻu holoʻokoʻa me ka ʻole o ka hōʻino ʻana i ka lolo. Ua kapa ʻia kēia ʻano ʻoki ʻana he "Craniotomy".
• Lapaʻau radiation: Hoʻohana ʻia nā kukuna X e pepehi i nā hunaola kanesa i koe ma hope o ke ʻoki ʻana. Pono paha ʻoe a hiki i 30 mau lāʻau lapaʻau i kēlā me kēia lā no kahi o ʻeono pule.
• IMRT (Intensity-modulated radiation therapy): He ʻano hana kūikawā kēia e kuhikuhi ana i ka radiation i ka puʻupuʻu wale nō, e hōʻemi ana i ka hōʻino ʻana i ka ʻiʻo lolo olakino.
• ʻO ke keʻena radio Stereotactic `(ʻO ke keʻena radio Stereotactic - Gamma Knife)`:Hoʻohana pū kēia i nā kukuna ikehu kiʻekiʻe i kuhikuhi ʻia i ka puʻupuʻu, e hōʻemi ana i ka hōʻino ʻana i nā ʻiʻo olakino. Hoʻohana pinepine ʻia kēia inā hoʻi hou ka GBM ma hope o IMRT.
• Kemoterapia: Hāʻawi ʻia nā lāʻau lapaʻau e pepehi i nā hunaola kanesa. Hele kēia mau lāʻau lapaʻau ma ke kahe koko o ke kino a hoʻouka i nā hunaola kanesa. Hāʻawi pinepine ʻia lākou me ka radiation therapy a laila hoʻomau ʻia.
• ʻO ka laser interstitial thermal therapy (LITT): He ʻano hana e hoʻohana ai i ka ikehu laser e "puhi" a luku i ka puʻupuʻu. Hoʻohana ʻia kēia i kekahi manawa.
• Lapaʻau i kuhikuhi ʻia: Hoʻopili ka lāʻau lapaʻau i kuhikuhi ʻia i nā loli kikoʻī o ke kelepona e kōkua i ka ulu ʻana o ka maʻi kanesa. Hiki ke hoʻohana ʻia kēia ma ke ʻano he koho ʻē aʻe i ka chemotherapy a i ʻole i ka hui pū ʻana me ia.
• Nā kahua lapaʻau puʻupuʻu (TTF): He ʻano hana e kāohi ai i ka ulu ʻana o nā hunaola kanesa ma o ka hoʻouna ʻana i nā kahua uila haʻahaʻa i ka puʻupuʻu ma o nā electrodes i hoʻopili ʻia i ke poʻo. Hoʻohana ʻia kēia ma hope o ka chemo-radiation therapy.
• Immunotherapy: Pili kēia i ka hoʻohana ʻana i ka ʻōnaehana pale ponoʻī o kou kino e hakakā i nā pūnaewele GBM. ʻOiai he lāʻau hoʻokolohua kēia, aia ka manaʻolana.
• Mālama palekana: Pili kēia i ka hōʻoluʻolu ʻana i nā hōʻailona, ​​​​ka hōʻemi ʻana i ka ʻeha, a me ka hāʻawi ʻana i ka hōʻoluʻolu naʻau. Hiki ke hāʻawi ʻia i kēlā me kēia pae o ka mālama ʻana.

ʻAʻohe lāʻau lapaʻau mau loa no Glioblastoma (GBM). Eia nō naʻe, hiki i kēia mau lāʻau lapaʻau ke hāʻawi i ka hōʻoluʻolu a kōkua i ka hoʻolōʻihi ʻana i ke ola no ka mea maʻi.

Āhea wau e ʻike ai i ke kauka?

Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona, ​​​​mai hoʻowahāwahā iā lākou. Pono ʻoe e ʻike koke i ke kauka.

• Nā pilikia hoʻomanaʻo, ʻoiai inā e ʻoi aku ka ʻino o ka hala ʻana o ka manawa.
• Ua kapa ʻia ke kūpono ʻana he "Seizures".
• ʻO ke poʻo ʻeha nui, ʻoiai i ke kakahiaka, ʻaʻole e hōʻoluʻolu ʻia e nā lāʻau ʻeha maʻamau.
• Nā pilikia maka, ʻike pālua, ʻike pōwehiwehi.
• Ka emi ʻana o ke kaumaha me ke kumu ʻole, a i ʻole ka loaʻa mau ʻana o ka nausea a me ka luaʻi ʻana.
• He ʻokoʻa maopopo i nā ʻano a me ke ʻano pilikino.
• Hoʻonui mālie ʻia ka nāwaliwali, ka maneʻo, a i ʻole ka paʻakikī i ka ʻōlelo ʻana.

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​ʻaʻole ia he manaʻo he Glioblastoma (GBM) kou. Eia nō naʻe, ʻoi aku ka maikaʻi o ke ʻike ʻana i ke kauka e ʻike i ke kumu.

Hiki ke pale ʻia ʻo Glioblastoma (GBM)?

ʻO ka mea pōʻino, ʻaʻohe ala e pale aku ai i nā hoʻololi genetic e hoʻoulu ai iā Glioblastoma (GBM), no ka mea, hiki pinepine kēia mau mea me ka ulia pōpilikia.

Eia nō naʻe, inā ʻike mua ʻia ka maʻi a hoʻomaka ka lāʻau lapaʻau, hiki ke lohi ka wikiwiki o ka laha ʻana o ka puʻupuʻu a hiki ke kaohi ʻia nā hōʻailona.

Inā ua loaʻa i kekahi o kou ʻohana nā puʻupuʻu lolo, ʻo ia hoʻi ke manaʻo nei ʻoe he pilikia hoʻoilina, makemake paha ʻoe e noʻonoʻo i ka hoʻāʻo ʻana i ka genetic. He mea nui e kamaʻilio me ke kauka a i ʻole ke kākāʻōlelo genetic e pili ana i ia mea a aʻo i nā pono a me nā pōʻino.

Ka Wānana o ka Maʻi Glioblastoma (GBM)

He maʻi ʻaʻai ʻino loa ʻo Glioblastoma (GBM), a ʻaʻole maikaʻi loa ka wānana. Inā ʻaʻole mālama ʻia, hiki i ka maʻi ke alakaʻi i ka make i loko o ka manawa pōkole o ka ʻike ʻia ʻana.

Eia nō naʻe, hiki i nā lāʻau lapaʻau o kēia manawa ke kōkua i ka hōʻemi ʻana i nā hōʻailona, ​​​​hāʻawi i ka hōʻoluʻolu i ka mea maʻi, a malia paha e hoʻolōʻihi i ke ola.

• Ke hoʻomau nei nā hoʻokolohua lapaʻau e ʻimi i nā lāʻau lapaʻau hou. Hiki i kēia ke alakaʻi i kahi lāʻau lapaʻau hou e kūpono iā ʻoe.
• Ke hāʻawi mai nei nā lāʻau lapaʻau e pili ana i nā genes cell cancer kikoʻī i nā hopena maikaʻi.
• Ke noiʻi nei nā kānaka noiʻi i nā ala e hāʻawi pololei ai i ka chemotherapy i ka puʻupuʻu lolo.
• ʻO ka maʻamau, noho ka hapa nui o ka poʻe ma waena o 12 a me 18 mau mahina ma hope o ka loaʻa ʻana o ka maʻi Glioblastoma (GBM).
• ʻO ka nui o ke ola ʻana no ʻelima makahiki no ka glioblastoma (GBM) ma kahi o 5% . ʻO ke ʻano kēia ma kahi o 5 o 100 mau kānaka me GBM e ola mau nei i ʻelima mau makahiki ma hope o ka hōʻoia ʻana.

ʻO ka ʻike ʻana he glioblastoma (GBM) kou he mea paʻakikī paha ia e hana ai. Ulu koke ka puʻupuʻu, a he mea paʻakikī paha ka mālama ʻana. Eia nō naʻe, ke hoʻomau nei nā mea noiʻi i ka ʻimi ʻana i nā lāʻau lapaʻau hou no GBM. Hiki i nā lāʻau lapaʻau o kēia manawa ke kōkua i ka hōʻemi ʻana i nā hōʻailona a hoʻomaikaʻi i kou ʻano ola. Hiki i kāu kauka ke alakaʻi iā ʻoe ma o kāu mau hana aʻe a kōkua iā ʻoe e loaʻa ka mālama a me ke kākoʻo āu e pono ai.

Nā mea nui e hoʻomanaʻo (Leka Lawe-Home)

No laila, ʻoiai he maʻi koʻikoʻi ʻo Glioblastoma (GBM), he mea nui e makaʻala iā ia a e ʻimi i ke aʻo lapaʻau i ka wā e ʻike ʻia ai nā hōʻailona. ʻO ka wā mua e ʻike ʻia ai, ʻoi aku ka maikaʻi o nā hopena lapaʻau.

E hoʻomau mau i kou manaʻolana no nā lāʻau lapaʻau hou a me nā hoʻokolohua lapaʻau. Ke holomua nei ka ʻepekema lapaʻau i kēlā me kēia lā.

Inā hiki kēia iā ʻoe a i ʻole kekahi āu i ʻike ai, e hoʻomanaʻo ʻaʻole ʻoe hoʻokahi. He mea waiwai nui ke kākoʻo a me ke aloha o nā kauka, nā kahu maʻi, ka ʻohana, a me nā hoaaloha i kēia manawa. ʻO ka noho ikaika ʻana i ka noʻonoʻo he ikaika nui hoʻi ia e kū ai i kēia pilikia.

` glioblastoma, gbm, maʻi ʻaʻai lolo, puʻupuʻu lolo, astrocytoma, astrocytoma, nā hōʻailona maʻi ʻaʻai, nā puʻupuʻu lolo, ka mālama ʻana i ka maʻi ʻaʻai