E aʻo hou aʻe kākou e pili ana i ka glucagon, ka mea e kōkua ai i ka kaohi ʻana i nā pae kō o kou kino.

Ua noʻonoʻo paha ʻoe pehea e kāohi ʻia ai ko mākou pae kō koko? Aia kekahi mea kūikawā e kōkua ana i kēia i kapa ʻia ʻo Glucagon. E like me ke koa liʻiliʻi i loko o ko mākou kino, mālama ʻo Glucagon i ko mākou pae kō koko mai ka haʻahaʻa loa. I kēia lā, e kamaʻilio mākou e pili ana i kēia Glucagon me nā kikoʻī a me ka maʻalahi loa.

He aha ka Glucagon?

I ka ʻōlelo maʻalahi, he hormone kūlohelohe ka glucagon a ko mākou kino e hana ai . Ua ʻike ʻoe, ua hana ʻia e nā cell alpha i loko o kā mākou pancreas. Ke hāʻule ko mākou pae glucose koko, ke ʻai ʻole mākou no ka manawa lōʻihi (hoʻokē ʻai lōʻihi), ke hoʻoikaika kino mākou, a i ʻole ke ʻai mākou i kahi meaʻai momona i ka protein, hoʻokuʻu ʻia kēia glucagon.

E noʻonoʻo e pili ana i ia mea, ʻo ka glucose ke ʻano nui o ke kō i loko o ko kākou koko. Loaʻa iā kākou kēia glucose mai nā kalapona i loko o nā mea a kākou e ʻai ai a inu ai. ʻO kēia kō ka mea e hāʻawi ai i ka ikehu i nā ʻōpū o ko kākou kino, nā ʻiʻo, a me ka ʻōnaehana nerve. Ua like ia me ka ʻaila no ke kaʻa. No laila, mālama mau ko kākou kino i kēia pae kō koko ma ka pae kūpono ma ke ʻano paʻakikī loa. Inā kiʻekiʻe loa kēia a haʻahaʻa loa paha, hiki ke loaʻa nā ʻano maʻi a me nā ʻoluʻolu ʻole.

Nā inikini Glucagon a me nā pīpī ihu

Ma waho aʻe o ka glucagon kūlohelohe, aia kekahi mau glucagon synthetic. Hiki ke hāʻawi ʻia kēia mau mea ma ke ʻano he injection a i ʻole he ihu maloʻo. Ua ʻike paha ʻoe i kēia i hoʻohana ʻia i nā pilikia, ʻoi aku hoʻi no ka poʻe me ka maʻi diabetes Type 1 , i ka wā e hāʻule koke ai ko lākou kō koko i lalo loa (hypoglycemia). ʻO ka glucagon i hāʻawi ʻia i kēia manawa e hoʻokuʻu i ka glucose i mālama ʻia i loko o ko mākou ake a hoʻokiʻekiʻe koke i ko mākou pae kō koko. Ua like ia me ka hāʻawi ʻana iā mākou i kahi 'boost' iki.

He aha ka hana a ka glucagon i ko mākou kino?

Inā hana pono kāu pancreas, e kāohi pono kou kino i kou pae glucose koko. Hana nui ʻia kēia e ʻelua mau hormones i kapa ʻia ʻo glucagon a me insulin . No ka laʻana, i ka wā e haʻahaʻa loa ai kou pae kō koko (hypoglycemia), hoʻokuʻu kāu pancreas i ka glucagon hou aku. Kōkua kēia glucagon i ka hoʻokiʻekiʻe ʻana i kou pae kō koko ma kekahi mau ʻano:

• ʻO ka mea mua, hele ka glucagon i ko kākou akepaʻa a hoʻololi i ka glucose i mālama ʻia ma laila - ka mea a kākou e kapa nei he glycogen - i mea hiki iā kākou ke hoʻohana. A laila hoʻokuʻu ke akepaʻa iā ia i loko o ke koko.
• ʻO ka lua, hiki i ka glucagon ke pale i ke akepaʻa mai ka lawe ʻana a me ka mālama ʻana i ka glucose, e waiho ana i ka glucose hou aʻe i loko o ke koko.
• ʻO ke kolu, nā waikawa aminoKōkua pū ʻo Glucagon i ke kino e hana i ka glucose mai nā kumu ʻē aʻe.

E hoʻomanaʻo, ua like ia me ka seesaw. Ke hāʻule ke kō koko, hana ka glucagon, a ke piʻi ke kō koko, hana ka insulin!

He aha nā maʻi e pili pū ana me nā pilikia me ka hana glucagon?

I kēia manawa, e nānā kākou i nā pilikia e hiki mai ana inā ʻaʻole hana pono ka glucagon.

Inā loaʻa iā ʻoe ka maʻi diabetes, ʻaʻole paha e hiki i kou kino ke hoʻokuʻu i ka glucagon lawa ke haʻahaʻa kou kō koko. Hiki i kēia ke hoʻonui i kou loaʻa ʻana o ke kō koko haʻahaʻa pinepine, a i ʻole ke kō koko haʻahaʻa loa . He kiʻekiʻe loa kēia pilikia inā ʻoe e lawe i nā lāʻau hoʻohaʻahaʻa kō koko e like me ka insulin a i ʻole sulfonylureas.

I kekahi poʻe me ka maʻi diabetes type 2, ʻoi aku paha ke kiʻekiʻe o nā pae glucagon ma mua o ka maʻamau, e pili ana i nā pae kō koko. ʻO kēia kekahi kumu no ke kiʻekiʻe o nā pae kō koko.

He mea kakaikahi loa nā pilikia me ka hana ʻana o ka glucagon me ka ʻole o ka maʻi diabetes, akā aia kekahi mau kūlana kahi e hiki ai ke hana:

• Pancreatitis: Inā loaʻa iā ʻoe ka maʻi diabetes ma muli o ka pancreatitis a lawe i ka insulin no ia mea, hiki iā ʻoe ke loaʻa i ka nele o ka glucagon. Hoʻonui kēia i ka pilikia o ke kō koko haʻahaʻa.
• Glucagonoma: He puʻupuʻu laha ʻole kēia o ka pancreas. Hoʻokuʻu ia i ka nui o ka glucagon. Hoʻoulu kēia i nā hōʻailona e like me ke kō koko kiʻekiʻe, ka ʻulaʻula o ka ʻili, a me ka pohō kaumaha.
• ʻO ka Multiple Endocrine Neoplasia (MEN): He ʻano laha ʻole kēia o ka genetic. I loko o kēia, ulu nā ʻōpū ma mua o hoʻokahi gland i loko o kāu ʻōnaehana endocrine. Hoʻokomo pū kēia i ka pancreas.
• Nā hopena ʻaoʻao o ka pancreatectomy: Inā no kekahi kumu e wehe ʻia ai kahi hapa a i ʻole kou pancreas āpau, e nalowale nā ​​​​​​mea e hana ana i ka glucagon a me ka insulin.

He aha nā hōʻailona o nā pilikia e pili ana i ka glucagon?

E like me kā mākou i kūkākūkā ai ma mua, hiki i nā ʻano ʻē i nā pae glucagon ke kumu i ke kō koko haʻahaʻa (hypoglycemia) a i ʻole ke kō koko kiʻekiʻe (hyperglycemia). E nānā kākou i kēlā mau hōʻailona.

Nā hōʻailona o ke kō koko haʻahaʻa (Hypoglycemia)

E noʻonoʻo ʻoe e lawe ana kāu hoaaloha, ʻo Nilanthi, i ka lāʻau lapaʻau no ka maʻi diabetes. I kekahi lā, hoʻomaka koke ʻo ia e haʻalulu, hou, a poniuniu. Me he mea lā ua ʻōlelo ʻo ia me ka ʻōlelo ʻole i ka wā e ʻōlelo ai. Inā loaʻa kēia mau hōʻailona, ​​​​​​hiki ke hōʻike ʻia he haʻahaʻa loa kona kō koko.

ʻO nā hōʻailona maʻamau:

• Haʻalulu, haʻalulu
• Ke hou nei a me ke anu nei
• Pōʻino, manaʻo māmā ke poʻo
• Nā palpitations o ka puʻuwai
• Pōloli
• Paʻakikī i ka noʻonoʻo ʻana, huikau

He mea nui: Inā ʻike ʻoe i kēia mau hōʻailona, ​​​​he mea nui loa ia e ʻai i kahi mea kō, kahi meaʻai waiwai i ka carbohydrate a i ʻole mea inu i ka hikiwawe loa . E kōkua kēia i kou pae kō koko e hoʻi i ka maʻamau. Inā ʻike pinepine ʻoe i kēia mau hōʻailona, ​​​​pono ʻoe e ʻike i kāu kauka.

Nā hōʻailona o ke kō koko kiʻekiʻe (Hyperglycemia)

ʻO ke kō koko kiʻekiʻe (hyperglycemia) pinepine ʻia e ka nele o ka insulin, ʻaʻole ia he pilikia me ka glucagon wale nō. Eia nō naʻe, hiki i nā pilikia glucagon kakaʻikahi ke hoʻoulu i ke kō koko kiʻekiʻe. ʻO nā hōʻailona mua:

• Ka makewai pinepine a me/a i ʻole ka pōloli
• ʻIke pōwehiwehi
• Ka mimi pinepine ʻana ( ka mimi pinepine ʻana)
• ʻEha poʻo

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​​​he mea nui loa e ʻike i ke kauka.

He aha nā hoʻokolohua e hana ʻia e nānā i nā pae glucagon?

Inā loaʻa iā ʻoe kekahi mau hōʻailona, ​​​​e kauoha paha kāu kauka i kahi hoʻāʻo koko e ana i kāu mau pae glucagon. Ma kēia hoʻāʻo, hoʻohana ke kauka a kahu maʻi paha i kahi nila e lawe i kahi hāpana koko mai kou aʻa. A laila hoʻouna ʻia i kahi lab no ka hoʻāʻo ʻana.

He aha nā pae glucagon maʻamau?

ʻO ka maʻamau, ʻo ka nui o ka glucagon e pono ai iā mākou i loko o ko mākou koko ma waena o 50 a me 100 picograms no ka milliliter (pg/mL) . ʻO ka picogram he hoʻokahi trillionth o ka gram! He liʻiliʻi loa ia, ʻeā?

Akā e hoʻomanaʻo, hiki ke ʻokoʻa iki kēia mau waiwai maʻamau mai kēlā me kēia keʻena hoʻokolohua. Hiki nō hoʻi ke ʻokoʻa ma muli o ka lōʻihi o kou hoʻokē ʻai ʻana a me kou mau pae kō koko i ka manawa o ka hoʻāʻo ʻana. No laila, e hoʻohālikelike mau i kāu mau hopena me nā waiwai ma kāu hōʻike hoʻāʻo koko . Inā he mau nīnau kāu, e kamaʻilio me kāu kauka.

Āhea wau e ʻike ai i ke kauka e pili ana i koʻu mau pae glucagon?

Inā loaʻa iā ʻoe ka maʻi diabetes a loaʻa pinepine iā ʻoe nā hanana o ke kō koko haʻahaʻa a kiʻekiʻe paha, he mea nui e ʻike i ke kauka. ʻAʻole ana pinepine ʻia nā pae Glucagon i ka poʻe me ka maʻi diabetes. Eia nō naʻe, pono paha ʻoe e hoʻololi i kāu hoʻokele maʻi diabetes e hōʻemi i kēia mau hanana.

ʻOiai he mea kākaʻikahi nā pilikia ʻē aʻe e pili ana i ka glucagon, inā loaʻa iā ʻoe nā hōʻailona, ​​​​he mea nui e ʻimi i ke kumu. No laila, e ʻike pono i kāu kauka.

He aha ka ʻokoʻa ma waena o Glucagon a me Glycogen?

ʻAʻole anei like kēia mau mea ʻelua? ʻO Glycogen kahi ʻano glucose (kō) i mālama ʻia i loko o ke ake.Hoʻopaʻa ko mākou kino i ka glycogen ma ke akepaʻa a me nā ʻiʻo.

He hormone ka Glucagon e hōʻailona ana i ke akepaʻa e hoʻololi i ka glycogen i glucose. A laila komo kēlā glucose i ke koko a hiki ke hoʻohana ʻia i ikehu e ko mākou kino.

He aha ka mea e hana ai i ka glucagon i ka wā hoʻokē ʻai?

I ka wā e hoʻokē ʻai ai kākou, he mea nui ka glucagon i ka mālama ʻana i ko kākou pae kō koko mai ka hāʻule ʻana i lalo loa. ʻO kēia no ka mea ʻaʻole i loaʻa i ko kākou kino ka glucose mai ka meaʻai i kēlā manawa.

Ke hoʻokē ʻai mākou no ka manawa lōʻihi, hoʻoulu ka glucagon i ke kino e hana i ka glucose mai nā mea ʻaʻole carbohydrate - e like me nā lipids, nā waikawa amino, a me nā protein. Ua kapa ʻia kēia kaʻina hana ʻo gluconeogenesis .

ʻO ka mea hope loa, pono wau e ʻōlelo... (Leka Lawe-Home)

No laila, ua maopopo paha iā ʻoe he hormone koʻikoʻi loa ka glucagon e kōkua ai i ka mālama ʻana i ko mākou pae kō koko olakino 'ma hope o nā hiʻohiʻona'. He mea paʻakikī loa ke loaʻa iā ʻoe ka maʻi diabetes a i ʻole nā ​​​​pilikia e pili ana i ka glucagon.

Eia nō naʻe, inā ʻike pinepine ʻoe i nā hōʻailona o ke kō koko haʻahaʻa a i ʻole ke kō koko kiʻekiʻe, e ʻoluʻolu e ʻike i kāu kauka. A laila hiki iā lākou ke ʻike i ke kumu a kuhikuhi i ka lāʻau āu e pono ai. ʻO ka mālama ʻana i kou olakino ka mea nui loa.

glucagon , kō koko, hypoglycemia, hyperglycemia, maʻi diabetes, pancreas, hormone