Ke manaʻo nei ʻoe i kekahi manawa ʻaʻohe ou ikaika, luhi mau, a maʻi mau? I kekahi manawa, hiki ke hana ʻia kēia mau hōʻailona pili ʻole e kahi pilikia ma kekahi o nā ʻāpana liʻiliʻi loa o ko mākou kino. I kēia lā, e kamaʻilio mākou e pili ana i kahi kūlana paʻakikī iki, akā he mea nui loa e ʻike. ʻO ia nā maʻi Mitochondrial.
ʻO ka mea mua, e nānā kākou, he aha nā mitochondria?
I ka ʻōlelo maʻalahi, he mau "hale mana" liʻiliʻi nā mitochondria i loko o kēlā me kēia cell i loko o ko mākou kino. E like me kā mākou hale hana mana e hoʻoikaika i ko mākou mau home, hoʻohana kā mākou mau cell i kēia mau mitochondria e hana i ka ikehu e pono ai lākou e hana. Ma ka hoʻohana ʻana i ka meaʻai a mākou e ʻai ai a me ka oxygen a mākou e hanu ai, hana kēia mau hale hana liʻiliʻi ma kahi o 90% o ka ikehu e pono ai ko mākou kino. No laila e noʻonoʻo i nā pilikia e hiki mai ana inā ʻaʻole hana pono kēia mau hale hana mana.
ʻAʻole nā maʻi mitochondrial he maʻi hoʻokahi. He huaʻōlelo laulā lākou no kahi hui o nā kūlana i loaʻa mai ka hana pono ʻole o kēia mau hale mana.
Ke hana pono ʻole kēia mau mea hana mana, ʻaʻole loaʻa i nā cell ka ikehu e pono ai. A laila lilo nā ʻōpū e loaʻa ana i kēlā mau cell i mea hana ʻole. Hiki i kēia ke hoʻopilikia i kekahi ʻāpana o ko mākou kino.
- lolo
- ʻŌnaehana nerve
- Nā ʻiʻo
- nā puʻupaʻa
- Puʻuwai
- Ake
- Nā maka
- Nā pepeiao
- ʻO ka pancreas
Hiki i kēia ke hoʻopilikia i kekahi mea.
He aha nā ʻano nui o nā maʻi mitochondrial?
Nui nā ʻano o kēia maʻi, akā ʻo kekahi o nā mea maʻamau:
- ʻO ka maʻi MELAS (Mitochondrial encephalopathy, lactic acidosis a me nā hanana like me ka hahau)
- ʻO ka neuropathy optic hereditary Leber (LHON)
- ʻO ka maʻi Leigh
- ʻO ka maʻi Kearns-Sayre (KSS)
- ʻO ka maʻi epilepsy myoclonic a me ka maʻi fiber ʻulaʻula (MERRF)
He mea paʻakikī paha kēia, akā e hoʻomanaʻo he mau kūlana kēia e hoʻoulu ai i nā hōʻailona like ʻole a ua hoʻokumu ʻia e nā loli i ka hana mitochondrial.
He aha nā hōʻailona o kēia mau maʻi?
ʻO kēia ka ʻāpana paʻakikī loa o ka maʻi. No ka mea, hiki ke ʻokoʻa loa nā hōʻailona mai kēlā kanaka a kēia kanaka, ma muli o ke ʻano o nā cell i hoʻopilikia ʻia a me kahi o ke kino e noho ai lākou. Loaʻa paha i kekahi poʻe nā hōʻailona palupalu loa , aʻo kekahi poʻe he nui loa nā hōʻailona. Hiki ke ʻokoʻa nā hōʻailona i loko o ka ʻohana hoʻokahi.
Hōʻike ka papa ma lalo nei i kekahi o nā hōʻailona maʻamau i ʻike ʻia i kēia mau maʻi.
| Māhele hōʻailona | Nā hōʻailona i ʻike ʻia |
|---|---|
| E pili ana i ka ulu ʻana a me ka ikaika | ʻAʻohe ulu ʻana no ka makahiki, nāwaliwali o nā ʻiʻo, ʻeha o nā ʻiʻo, a me ke kino make. |
| E pili ana i ka ʻike a me ke aʻo ʻana | Ka hemahema o ka ʻike a me/a i ʻole ka lohe, nā pilikia aʻo, a i ʻole nā lohi o ka ulu ʻana. |
| E pili ana i ka ʻōnaehana hoʻoheheʻe | Ka luaʻi ʻana me ka ʻike ʻole ʻia, ka maʻi pākī a i ʻole ka paʻa ʻana o ka ʻōpū, ka paʻakikī o ka mimi ʻana, ka reflux waikawa. |
| Pili i ka ʻōnaehana nerve | Nā ʻūhū, migraines, nāwaliwali. |
| Nā hiʻohiʻona ʻē aʻe | Paʻakikī ka hanu ʻana, ke kulou ʻana o ka lihilihi (ptosis). |
Hiki ke hoʻomaka kēia mau hōʻailona i ka wā hānau a i ʻole e ʻike ʻia i kēlā me kēia makahiki o ke ola. Hoʻomaopopo pinepine ke kauka i kēia ke ʻike ʻia nā hōʻailona i ka manawa like ma kekahi mau ʻōnaehana ʻōpū pili ʻole.
No ke aha e loaʻa ai kēia ʻano maʻi?
ʻO ke kumu nui o kēia, ʻo ia nā hewa genetic .
I ka ʻōlelo maʻalahi, loaʻa i nā mitochondria i loko o kā mākou mau cell nā kuhikuhi e hana i ka ikehu mai kā mākou DNA. Inā he loli a mutation paha i loko o kēia DNA, ʻaʻole loaʻa i nā mitochondria nā kuhikuhi pololei. A laila ʻaʻole hiki iā lākou ke hana pono i ka ikehu. Hiki i kēia ke hōʻino i nā cell a make paha lākou i ka wā ʻōpiopio.
Pehea e loaʻa ai i kekahi kēia maʻi?
He mau maʻi hoʻoilina kēia, ʻo ia hoʻi, hiki ke hoʻoili ʻia mai nā mākua a i nā keiki. I kekahi manawa, ʻoiai inā ʻaʻohe mea o ka ʻohana i loaʻa i ka maʻi, hiki i kekahi ke loaʻa i ka maʻi ma muli o kahi hoʻololi hoʻoilina maʻamau.
ʻO kahi ʻoiaʻiʻo kūikawā, he DNA kūikawā ko nā mitochondria. ʻO nā maʻi i hoʻokumu ʻia e nā hemahema i loko o kēia DNA mitochondrial e hoʻoilina wale ʻia mai ka makuahine a i nā keiki.
Hiki i nā maʻi ʻē aʻe ke hōʻino i ka hana mitochondrial?
ʻAe. Ua kapa ʻia ʻo ia he secondary mitochondrial dysfunction. ʻO ia hoʻi, ʻaʻohe ou maʻi mitochondrial genetic, akā aia kekahi maʻi olakino e hana pono ʻole ai kāu mitochondria. Eia kekahi laʻana:
- ka maʻi o Alzheimer
- ʻO ka dystrophy muscular
- ʻAno 1 diabetes
- ʻO ka sclerosis lehulehu (MS)
- Kekahi mau ʻano maʻi ʻaʻai
Hiki ke hoʻopilikia ʻia ka Mitochondria e nā maʻi e like me:
Pehea e ʻike ai i kēia maʻi?
Hiki ke paʻakikī iki ka ʻike ʻana i kēia maʻi no ka mea he ʻokoʻa loa nā hōʻailona. ʻAʻole hiki ke ʻike ʻia me hoʻokahi hoʻāʻo wale nō. Hiki i kāu kauka ke holo i kekahi mau hoʻāʻo.
- He loiloi piha o kāu mōʻaukala olakino a me kou ʻohana .
- Ke hana ʻana i kahi hoʻokolokolo kino piha.
- He hoʻāʻo e pili ana i ka ʻōnaehana nerve .
- Nā hoʻāʻo koko a me ka mimi . I kekahi manawa hiki ke hana ʻia kahi spinal tap.
- Ka hoʻāʻo ʻana i ka DNA .
- Ma muli o nā hōʻailona, hiki ke hana ʻia nā hoʻokolohua e like me ka MRI scan, kahi EKG a i ʻole Echocardiogram o ka puʻuwai, nā hoʻokolohua maka, nā hoʻokolohua lohe, a me nā hoʻokolohua EEG e nānā i ka hana o ka lolo .
- I kekahi manawa pono paha e lawe i kahi ʻāpana liʻiliʻi o ka ʻili a i ʻole ke ʻiʻo (biopsy) a nānā iā ia ma lalo o kahi microscope.
No laila, he mea nui loa ke kūkākūkā ʻana me ke kauka a i ʻole ka haukapila i loea i kēia ʻano maʻi no ka ʻike ʻana.
He aha nā lāʻau lapaʻau?
ʻO ka mea pōʻino, ʻaʻohe lāʻau lapaʻau no ka maʻi mitochondrial i kēia manawa. Eia nō naʻe, aia nā ʻano lapaʻau like ʻole e kōkua i ka hoʻokele ʻana i nā hōʻailona a pale i nā pilikia e hoʻoweliweli ana i ke ola .
- Nā lāʻau lapaʻau e hōʻemi ana i nā hōʻailona:Eia kekahi laʻana, lāʻau lapaʻau anti-epileptic.
- Nā huaora a me nā mea hoʻohui: ʻO nā mea e like me ka riboflavin, coenzyme Q10, a me ka carnitine he mea kōkua paha no kekahi poʻe.
- Nā hoʻololi ʻana i ka meaʻai a me ka hoʻoikaika kino: E paipai kāu kauka i kēia mau mea ma muli o kou kūlana.
- Hoʻōla kino, hoʻōla hana, a i ʻole ka lāʻau hoʻōla ʻōlelo .
- Ke komo ʻana i nā mea kōkua e like me nā mea kōkua hoʻolohe .
ʻO ka mea e pono ai no kekahi kanaka, ʻaʻole paha e pono no kekahi, no laila ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka a hana i kahi hoʻolālā lapaʻau kūpono iā ʻoe.
Hiki ke pale ʻia ka maʻi mai ka hoʻonui ʻia ʻana?
ʻOiai ʻaʻohe ala e pale aku ai i kēia maʻi mai ka ulu ʻana, hiki iā ʻoe ke noho mamao mai kekahi mau mea e hoʻonui ai i nā hōʻailona.
- E pale i ka hoʻopili ʻana i ke anu nui a i ʻole ka wela nui .
- Mai hōʻalo i nā meaʻai.
- E hiamoe maikaʻi i ka pō.
- E noho mamao aku mai ke kaumaha i ka hiki.
Hiki i kāu kauka ke aʻo aku iā ʻoe e mālama i ka ikehu ma mua o ka hoʻolilo ʻana i ka ikehu a pau o kou kino i ka manawa hoʻokahi.
Āhea wau e ʻike ai i ke kauka?
Inā loaʻa iā ʻoe nā hōʻailona o ka maʻi mitochondrial a ke paʻakikī nei ʻoe e hana i kāu mau hana i kēlā me kēia lā, e ʻike pono i ke kauka.
Inā loaʻa iā ʻoe kahi maʻi ʻōhū a i ʻole ka pilikia nui o ka hanu ʻana, e hele koke i ka ʻOihana Pilikia (ETU) o ka haukapila.
Hiki ke paʻakikī ke ʻike ʻana ua loaʻa iā ʻoe a i ʻole kahi mea aloha kēia maʻi. Akā e hoʻomanaʻo, aia kou ʻohana, nā hoaaloha, a me ka hui lapaʻau, me nā kauka, e kōkua iā ʻoe e ola me ka holomua me kēia mau hōʻailona.
Leka Lawe-Home
- ʻO nā maʻi Mitochondrial kahi hui o nā maʻi genetic i hoʻokumu ʻia e ka hana pono ʻole o nā "mea kanu mana" e hana ana i ka ikehu no kā mākou mau cell.
- He ʻokoʻa loa nā hōʻailona a hiki ke komo pū me ka nāwaliwali o nā mākala, ka hemahema o ka ʻike/lohe, nā pilikia aʻo, a me ka maʻi ʻeha.
- He paʻakikī ka ʻike ʻana i kēia maʻi a koi ʻia kekahi mau hoʻokolohua lapaʻau. He mea nui e ʻike i kahi loea no kēia.
- ʻOiai ʻaʻole hiki ke ho'ōla loa ʻia ka maʻi, aia nā ʻano lapaʻau like ʻole e hiki ai ke kaohi i nā hōʻailona a hoʻomaikaʻi i ka maikaʻi o ke ola.
- Hiki ke kāohi ʻia ka hoʻonui ʻia o nā hōʻailona ma ka pale ʻana i nā mea e like me ke kaumaha, ka hiamoe ʻole, a me ke kiʻekiʻe o ka mahana.
- Inā loaʻa iā ʻoe a i ʻole kekahi āu i ʻike ai kēia mau hōʻailona, mai kānalua e ʻimi i ke kōkua lapaʻau.
💬 Comments (0)
ʻAʻohe manaʻo i kau ʻia. Hoʻohui i kāu manaʻo ma ʻaneʻi no ka manawa mua.
Hoʻohui i kāu manaʻo