Ke noʻonoʻo ʻoe i ka maʻi diabetes, manaʻo paha ʻoe i ke ʻano 1 a me ke ʻano 2 wale nō. ʻIke ka hapa nui o ka poʻe o ko kākou kaiāulu a kamaʻilio e pili ana i kēia mau ʻano nui ʻelua. Akā, ua ʻike anei ʻoe aia kekahi mau ʻano maʻi diabetes ʻaʻole pili pono i kēia mau ʻano ʻelua, he ʻokoʻa iki, a ʻaʻole mākou i lohe nui e pili ana? ʻO MODY lāua ʻo LADA ʻelua mau ʻano maʻi diabetes kakaʻikahi, akā he mea nui loa ia e makaʻala. Hiki i kēia mau mea ke loaʻa kekahi o nā ʻano o ke ʻano 1 a me ke ʻano 2, akā he mau hōʻailona a me nā lāʻau lapaʻau koʻikoʻi ko lākou. E kamaʻilio kākou e pili ana i kēia me ka maʻalahi a me ke aloha i kēia lā.
E nānā mua kākou i ke ʻano o MODY? (Maturity-Onset Diabetes of the Young)
I ka ʻōlelo maʻalahi, ʻo MODY kahi maʻi genetic e hoʻoulu ai i ka maʻi diabetes. E noʻonoʻo i ko mākou kino e like me kahi hale hana paʻakikī. Loaʻa i kēia hale hana nā ʻano kuhikuhi like ʻole (genes) no nā hana like ʻole. No laila, inā he loli liʻiliʻi a hewa paha (kapa mākou i kēia he mutation gene) i loko o ka hoʻonohonoho o nā kuhikuhi e hana ai i ka hormone "Insulin", ka mea e kōkua ai i ke kino e hoʻohana i ke kō e hana i ka ikehu e pono ai, ʻaʻole hiki i ke kino ke hana pono i ka insulin. A laila piʻi ka pae kō koko. ʻO MODY kekahi ʻano maʻi.
E like me ka inoa e hōʻike nei ('Maturity-Onset Diabetes of the Young'), ʻike pinepine ʻia kēia maʻi i nā poʻe ʻōpio, mai ko lākou wā ʻōpio a hiki i ka wā ʻōpio. Eia nō naʻe, he mea kakaikahi loa ia. Ma kahi o 5% wale nō o ka poʻe me ka maʻi diabetes i loaʻa iā MODY.
He aha nā hōʻailona o MODY?
Hiki ke ʻokoʻa nā hōʻailona o MODY mai kēlā kanaka a kēia kanaka no ka mea ʻokoʻa ke ʻano o nā hōʻailona ma muli o ka mutation gene e hoʻopilikia ai iā ia.
Akā ma ke ʻano laulā, he akahai loa nā hōʻailona o MODY a ulu mālie. ʻO ia ke kumu e ʻike wale ai ka poʻe he nui i loaʻa iā lākou ke ʻano ke hōʻike ʻia kahi hoʻāʻo koko no kekahi kumu ʻē aʻe i nā pae kō koko kiʻekiʻe.
Akā inā ʻike ʻia nā hōʻailona, ua like paha lākou me nā ʻano maʻi diabetes ʻē aʻe.
| Nā hōʻailona maʻamau |
|---|
| Ke make wai nei ma mua o ka maʻamau. |
| Pono pinepine e mimi. |
| ʻIke pōwehiwehi. |
| Nā maʻi pinepine (ʻoi aku hoʻi ka ʻili a me ke ala mimi). |
Pehea lā e kānalua ai ke kauka ua loaʻa iā ʻoe ʻo MODY?
Ke hōʻoia ʻia ke kiʻekiʻe o kou pae kō koko, e loaʻa i kāu kauka kekahi mau kumu e manaʻo ai he MODY paha kāu.
- Ua loaʻa iā ʻoe ka maʻi diabetes i kou wā ʻōpiopio .
- Loaʻa ka maʻi diabetes i nā hanauna he nui o kou ʻohana (no ka laʻana, ua loaʻa pū kekahi maʻi diabetes i kou makuahine/makua kāne, a me kou kupuna wahine/kupuna kāne).
- ʻAʻohe ou hōʻailona maʻamau o ka maʻi diabetes Type 1 a i ʻole Type 2 (e.g., momona, koko kiʻekiʻe).
Inā kānalua kāu kauka he MODY kou no kēia mau kumu, hiki iā ia ke kuhikuhi iā ʻoe e hana i kahi hoʻāʻo genetic e hōʻoia i kou kūlana MODY. Hana pinepine ʻia kēia ma ka hoʻouna ʻana i kahi hāpana koko a i ʻole ka lawai i kahi keʻena hoʻokolohua.
No laila he aha ka LADA? (Latent Autoimmune Diabetes i nā pākeke)
ʻAe, i kēia manawa ua maopopo iā ʻoe ʻo MODY. I kēia manawa e nānā kākou i kēia ʻano ʻē aʻe i kapa ʻia ʻo LADA. Ua kapa ʻakaʻaka kekahi poʻe iā ia he "diabetes Type 1.5." Aia ke kumu no kēlā.
E like me ka maʻi diabetes Type 1, ua hoʻokumu ʻia ʻo LADA e kahi pilikia autoimmune . I ka ʻōlelo maʻalahi, hoʻouka hewa ka ʻōnaehana pale o ko mākou kino (ʻōnaehana pale) a luku i nā hunaola e hana ana i ka insulin i loko o kā mākou pancreas ponoʻī. Ua like ia me kahi pūʻali koa e pale aku ana i kahi ʻāina e hoʻouka hewa ana i kona kūlanakauhale ponoʻī.
Ke luku ʻia nā pūnaewele e hana ana i ka insulin ma kēia ʻano, ʻaʻole hiki i ke kino ke kāohi i nā pae kō koko. Eia nō naʻe, ʻo ka ʻokoʻa nui ma ʻaneʻi i hoʻohālikelike ʻia me ka maʻi diabetes Type 1, ʻo ia ka lohi loa o kēia luku ʻana. No laila hiki ke hala nā mahina, a i ʻole nā makahiki, ma mua o ka ʻike ʻia ʻana o nā hōʻailona a pono ka lāʻau lapaʻau.
He aha nā hōʻailona o LADA?
Ua like loa nā hōʻailona o LADA me ko ke ʻano 1 a me ke ʻano 2. Eia naʻe, ʻike mālie ʻia lākou.
| Nā hōʻailona maʻamau |
|---|
| Ke manaʻo nei i ka make wai nui a me ka pono e mimi pinepine. |
| Ka pohō kaumaha ʻoiai ka makemake maikaʻi. |
| ʻIke pōwehiwehi. |
| Ka luhi nui a me ka nāwaliwali o ke kino. |
| ʻIli maloʻo a ʻānai. |
| Ke manaʻo nei i kahi ʻano ʻūlū ma nā lālā. |
| Nā maʻi pinepine. |
Pehea e ʻike ʻia ai a mālama ʻia ai ʻo LADA?
Hoʻomaka pinepine ka LADA ma hope o 30 mau makahiki. ʻO ia ke kumu e hiki ai i nā kauka ke kuhihewa iā ia no ka maʻi diabetes Type 2. Eia nō naʻe, inā ʻaʻole i kāohi ʻia kou kūlana me nā lāʻau lapaʻau maʻamau no Type 2, kānalua paha kāu kauka iā LADA.
ʻO ke ala wale nō e hōʻoia ai inā loaʻa iā ʻoe ʻo LADA me ka hoʻāʻo koko. Nānā kēia i nā antibodies i loko o kou koko i hana ʻia e kūʻē i nā cell hana insulin i loko o kāu pancreas. Eia kekahi, hiki i kāu kauka ke kauoha i kahi hoʻāʻo e nānā i kou pae o kahi protein i kapa ʻia ʻo C-peptide, ʻo ia ke ana o ka nui o ka insulin a kou kino e hana nei.
I ka wā e pili ana i ka mālama ʻana, i nā wā mua, hiki ke kaohi ʻia ka maʻi diabetes me nā lāʻau lapaʻau, ka ʻai, a me nā loli o ke ʻano o ka nohona.
Akā e hoʻomanaʻo, ma LADA, hoʻopau mālie ke kino i nā hunaola e hana ai i ka insulin, no laila i kekahi manawa pono ʻoe e lawe i nā pana insulin e kaohi i kou kō koko.
Leka Lawe-Home
- Ke kamaʻilio mākou e pili ana i ka maʻi diabetes, ʻaʻole ia wale nō ke ʻano 1 a me ke ʻano 2. Aia kekahi mau ʻano a mākou i ʻike nui ʻole ai, e like me MODY lāua ʻo LADA, akā he mea nui lāua.
- MODYHe ʻano maʻi diabetes ia e kū mai ana i ka wā ʻōpiopio a ua hoʻokumu ʻia e kahi kumu genetic. Aia kona mālama ʻana i ka gene e hoʻopilikia ana iā ia.
- He ʻano maʻi diabetes ʻo LADA e ulu mālie ana i ka wā makua, e like me ka maʻi diabetes Type 1. I ka hala ʻana o ka manawa, pono ia e mālama ʻia me ka insulin.
- Inā loaʻa iā ʻoe ka maʻi diabetes, a i ʻole kekahi o kou ʻohana i loaʻa iā ia, a ʻike ʻia kāu mau hōʻailona a i ʻole ka pane ʻana i ka lāʻau lapaʻau he "ʻano ʻokoʻa iki," mai makaʻu e kamaʻilio me kāu kauka e pili ana i kēia mau kūlana, i kapa ʻia ʻo MODY a me LADA. ʻO ka loaʻa ʻana o ka hōʻailona kūpono ka hana mua i ka loaʻa ʻana o ka lāʻau kūpono.
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