Loaʻa koke iā ʻoe ke koko kiʻekiʻe? A i ʻole e hou wale ʻoe? Loaʻa iā ʻoe ka ʻeha poʻo me ka puʻuwai e kuʻi ana? Mai wikiwiki e manaʻo he maʻi koʻikoʻi kekahi o kēia mau mea. Eia nō naʻe, inā hoʻomau kēia mau hōʻailona, ʻoiai me ke koko kiʻekiʻe i paʻakikī ke kāohi, he manaʻo maikaʻi e hopohopo iki. I kēia lā e kamaʻilio mākou e pili ana i kahi maʻi i kakaikahi iki, akā inā ʻike pono ʻia, hiki ke mālama maikaʻi ʻia. ʻO ia ka pheochromocytoma.
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He aha ka Pheochromocytoma? E hoʻomaopopo maʻalahi kākou.
I ka ʻōlelo maʻalahi, ʻo ka pheochromocytoma kahi puʻupuʻu e ulu ana ma ka ʻaoʻao waena o nā kelepa adrenal, ʻo ia hoʻi ka adrenal medulla. Hoʻokumu ʻia kēia mau puʻupuʻu e kahi ʻano cell kūikawā i kapa ʻia ʻo nā cell chromaffin. Hoʻopuka a hoʻokuʻu kēia mau cell i nā hormones i loko o ke kahe koko e pono ai no ka pane "hakakā a lele paha" o ko mākou kino. E noʻonoʻo e pili ana i ia mea, i ka wā e makaʻu koke ai ʻoe a i ʻole e kū i ka nui o ke kaumaha, nā loli e hana ʻia i loko o kou kino - piʻi ka helu o kou puʻuwai, hou ʻoe, haʻalulu kou kino - ʻo kēia mau hormones ke kuleana no kēia.
ʻO ka maʻamau, ulu ka Pheochromocytoma i hoʻokahi wale nō kelepa adrenal. Eia nō naʻe, i kekahi manawa hiki ke ulu i nā kelepa ʻelua. Hiki ke loaʻa ma mua o hoʻokahi puʻupuʻu i loko o hoʻokahi kelepa.
ʻO ka mea nui, ʻo ka hapa nui o nā pheochromocytomas he benign (ʻaʻole malignant) . ʻO ke ʻano kēia, ʻaʻole lākou e laha i nā ʻāpana ʻē aʻe o ke kino. Eia nō naʻe, ma waena o 10% a me 15% hiki ke lilo i maʻi kanesa. Inā he maʻi kanesa kēia, ua wehewehe ʻia i kekahi mau ʻano nui, ma muli o ke ʻano o kona laha ʻana:
- ʻO ka pheochromocytoma kūloko: Aia ka puʻupuʻu ma hoʻokahi a i ʻole nā ʻelua mau kelepa adrenal.
- ʻO ka pheochromocytoma ʻāpana: Ua pālahalaha ke kanesa i nā lymph nodes kokoke i nā kelepa adrenal a i ʻole nā ʻiʻo ʻē aʻe.
- ʻO ka pheochromocytoma metastatic: Ua pālahalaha ke kanesa i nā ʻōpū mamao e like me ke ake, nā māmā, a i ʻole nā iwi.
- ʻO ka pheochromocytoma hou: Ua hoʻi hou mai ke kanesa ma hope o ka mālama ʻia ʻana. Hiki ke noho ma kahi like me ia ma mua a i ʻole ma kahi ʻē aʻe.
He aha kēia mau kelepa adrenal i loko o ko kākou kino? He aha kā lākou hana?
Loaʻa iā kākou ʻelua mau kelepa adrenal. Aia lākou ma ke kua o ko kākou ʻōpū, ma luna o ko kākou mau puʻupaʻa, e like me ke pāpale. He ʻāpana lākou o kā kākou ʻōnaehana endocrine. ʻElua ʻāpana nui o kēlā me kēia kelepa adrenal. Ua kapa ʻia ka papa waho ʻo ka adrenal cortex, a ua kapa ʻia ka ʻāpana waena ʻo ka adrenal medulla.
Hoʻopuka ko mākou medulla adrenal i kahi hui o nā hormones i kapa ʻia he catecholamines. Hoʻomalu kēia mau hormones i kekahi mau kaʻina hana koʻikoʻi loa i loko o ko mākou kino:
- Ka helu o ka puʻuwai
- Ke koko
- Ka pae kō koko (Blood glucose)
- Pehea e pane ai ko mākou kino i ke kaumaha (ka pane "hakakā a lele paha")
ʻO nā ʻano nui o nā catecholamines:
- Dopamine
- ʻEpinephrine (Adrenaline) (Epinephrine / Adrenaline)
- Norepinephrine (Noradrenaline) (Norepinephrine / Noradrenaline)
Ke loaʻa ka pheochromocytoma, hiki iā ia ke hoʻokuʻu i nā hormones hou aʻe, adrenaline a me noradrenaline, i loko o ke koko ma mua o ka mea e pono ai. ʻO ia ka manawa e hoʻomaka ai nā hōʻailona like ʻole e ʻike ʻia.
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Check Availability →He aha ka ʻokoʻa ma waena o Pheochromocytoma a me Paraganglioma?
He ʻelua ʻano puʻupuʻu like loa kēia a kakaikahi. Kū mai nā mea ʻelua mai nā pūnaewele chromaffin like a mākou i kūkākūkā ai ma mua. Eia nō naʻe, kū mai ka pheochromocytoma ma ka ʻaoʻao waena o ka ʻōpū adrenal (ka adrenal medulla), ʻoiai kū mai ka paraganglioma ma nā wahi ʻē aʻe ma waho o ka ʻōpū adrenal .
ʻO wai ka mea e loaʻa pinepine ai kēia maʻi? Pehea ka maʻamau?
Hiki ke ulu aʻe ka Pheochromocytoma i kēlā me kēia makahiki, akā ʻoi aku ka maʻamau i ka poʻe ma waena o 30 a me 50 mau makahiki. Ma kahi o 10% o nā hihia i hōʻike ʻia i ka wā kamaliʻi.
He puʻupuʻu laha ʻole kēia. He mea paʻakikī ke ʻōlelo pololei i ka nui o ka poʻe i loaʻa i kēia maʻi. No ka mea ʻaʻole hōʻike kekahi poʻe i kekahi mau hōʻailona, hiki ke ʻike ʻole ʻia ka maʻi. Ua manaʻo ʻia he emi ma mua o 1% o ka poʻe me ke koko kiʻekiʻe he pheochromocytoma.
He aha nā hōʻailona e hōʻike ai ke kanaka me ka pheochromocytoma?
ʻIke ʻia nā hōʻailona Pheochromocytoma ke hoʻokuʻu nui ka puʻupuʻu i nā hormones adrenaline (epinephrine) a i ʻole noradrenaline (norepinephrine) i loko o ke koko. Eia nō naʻe, ʻaʻole hana nui kekahi mau puʻupuʻu i kēia mau hormones a hiki ke lilo i asymptomatic.
ʻO nā hōʻailona i ʻike pinepine ʻia:
- Ke koko kiʻekiʻe (Hypertension): ʻO kēia ka hōʻailona nui. I kekahi manawa he paʻakikī ke kāohi.
- ʻEha poʻo: Hiki ke lilo i ʻeha poʻo koʻikoʻi a koke.
- Ka hou nui ʻana me ke kumu ʻole.
- ʻO nā palpitations kahi manaʻo o ka puʻuwai wikiwiki, kūpono ʻole, a i ʻole ke kuʻi ʻana.
- Manaʻo e haʻalulu ana kou kino.
Nā hōʻailona maʻamau ʻole:
- ʻEha umauma a/a i ʻole ʻeha ʻōpū.
- Ua lilo koke ka ʻili i keʻokeʻo ma mua o ka maʻamau.
- Ka luaʻi a me/a i ʻole ka luaʻi ʻana.
- Ka maʻi pākī.
- Ka paʻa ʻana o ka ʻōpū.
- ʻO ka hypotension Orthostatic ka emi koke ʻana o ke koko ke kū ʻoe i luna. ʻO ke ʻano kēia e manaʻo ʻoe i ka poniuniu ke kū koke ʻoe mai kahi kūlana noho.
- Ka pohō kaumaha me ke kumu ʻole.
Hiki ke ʻike ʻia a ʻoi aku paha ka ʻino o kēia mau hōʻailona ma hope o kekahi mau hanana. Eia kekahi laʻana:
- Hana kino ikaika.
- Ka ʻeha kino a i ʻole ke kaumaha nui o ka noʻonoʻo.
- Ka hānau ʻana.
- Ke loaʻa nei i ka anesthesia.
- Ke hana ʻoki kino ʻana.
- Ka ʻai ʻana i nā meaʻai waiwai i ka tyramine (e like me ka waina ʻulaʻula, kokoleka, tīhi).
Aia mau anei nā hōʻailona? A i ʻole hele mai a hele aku lākou?
Hiki i ke kanaka me ka pheochromocytoma ke loaʻa ke koko kiʻekiʻe mau, a i ʻole e hele mai a hele aku .
Hiki i kekahi poʻe ke loaʻa i nā "hoʻouka paroxysmal," a i ʻole nā hoʻouka koke ʻana o nā hōʻailona. ʻO ke ʻano kēia, aia ka piʻi koke ʻana o ke koko, me nā hōʻailona e like me ke poʻo ʻeha nui, ka piʻi ʻana o ka puʻuwai, a me ka hou nui. Hiki i kēia mau "hoʻouka" ke hana i nā manawa he nui i ka lā, a i ʻole hoʻokahi a ʻelua paha i ka mahina.
Mea nui: Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, ʻoiai ke koko kiʻekiʻe koke, ka ʻeha poʻo, ka hou ʻana, a me ka palpitations, he mea nui loa ia e ʻimi i ke kōkua lapaʻau.
No ke aha e ulu ai ka pheochromocytoma? He aha nā kumu?
I ka hapanui o nā hihia, ʻaʻole hiki ke loaʻa ke kumu kikoʻī no ka pheochromocytoma. Loaʻa ia ma ke ʻano hūpō.
Eia nō naʻe, ma 25% a 35% o nā hihia, pili kēia kūlana i nā kūlana hoʻoilina. ʻO kekahi o nā mea nui:
- ʻO ka maʻi neoplasia endocrine lehulehu 2, nā ʻano A a me B (MEN2A a me MEN2B)
- ʻO ka maʻi Von Hippel-Lindau (VHL)
- ʻAno Neurofibromatosis 1 (NF1)
- ʻO ka maʻi paraganglioma hoʻoilina
- ʻO ke kaulahao Carney-Stratakis [paraganglioma a me ka puʻupuʻu stromal gastrointestinal (GIST)]
- ʻO Carney triad (paraganglioma, GIST a me ka chondroma pulmonary)
Ma waho aʻe o kēia mau kūlana genetic, hiki ke ulu aʻe ka pheochromocytoma ma muli o nā mutations ma ka liʻiliʻi he 10 mau genes like ʻole.
Pehea e ʻike ʻia ai kēia maʻi? (Diagnosis)
Hiki ke paʻakikī ke ʻike i ka Pheochromocytoma no ka mea he puʻupuʻu laha ʻole ia a i kekahi manawa ʻaʻole ia e hōʻike i nā hōʻailona. I kekahi manawa, ʻike ʻia ka puʻupuʻu ma ka hanana i ka wā o kahi hoʻāʻo i hana ʻia no kekahi kumu ʻē aʻe.
Aia kekahi mau kumu e kānalua ai ke kauka i kēia maʻi:
- NāuʻO kahi moʻolelo lapaʻau kikoʻī, ʻoiai inā ua loaʻa i kekahi o ka ʻohana ka pheochromocytoma ma mua.
- He hoʻokolokolo kino a me ka hoʻokolokolo lapaʻau piha.
- ʻO kekahi mau hōʻailona kikoʻī , no ka laʻana nā "hoʻouka kaua paroxysmal" a mākou i kamaʻilio ai a me ke koko kiʻekiʻe i kāohi ʻole ʻia e nā lāʻau lapaʻau maʻamau.
He aha ke ʻano o nā hoʻokolohua e hana ʻia?
Hiki i kāu kauka ke ʻōlelo i nā hoʻokolohua aʻe e hōʻoia inā he pheochromocytoma kāu:
- Hoʻāʻo mimi 24-hola: Pili kēia i ka hōʻiliʻili ʻana i kāu mimi i ka lā a me ke ana ʻana i ka nui o nā catecholamines i loko. Ana pū ia i nā mea i hana ʻia ke wāwahi ʻia kēia mau hormones. Inā ʻoi aku ke kiʻekiʻe o kēia mau pae ma mua o ka maʻamau, he hōʻailona paha ia o ka pheochromocytoma.
- Nā hoʻāʻo catecholamine koko: Ke ana kēia i nā pae o nā catecholamine i loko o ke koko. E like me nā hoʻāʻo mimi, ke nānā pū nei lākou i nā mea i hana ʻia e ka haki ʻana o nā hormones.
- ʻO ke scan CT (Computer Tomography scan): Lawe kēia i kahi moʻo o nā kukuna X e hana i nā kiʻi kikoʻī o loko o kou kino. Hiki i kāu kauka ke ʻōlelo i kēia e nānā i kāu mau kelepa adrenal.
- ʻO ke kiʻi MRI - Magnetic Resonance Imaging): Hoʻohana kēia i kahi magnet, nā nalu lekiō, a me kahi kamepiula e hana i nā kiʻi kikoʻī o loko o ke kino. Hoʻohana ʻia nō hoʻi ia e nānā i nā kelepa adrenal.
Ke hōʻoia ʻia ka maʻi, hiki ke hana ʻia nā hoʻokolohua hou aʻe e hoʻoholo ai inā he maʻi kanesa (malignant) a benign paha (benign) ka puʻupuʻu, a inā ua pālahalaha aku i nā ʻāpana ʻē aʻe o ke kino.
No ke aha he mea nui ka hoʻāʻo ʻana i ka Genetic?
Inā ua ʻike ʻia ʻoe me ka pheochromocytoma, e ʻōlelo paha kāu kauka i ka ʻōlelo aʻoaʻo genetic a me ka hoʻāʻo ʻana e hoʻoholo ai inā he maʻi hoʻoilina kou e hoʻopilikia ai iā ʻoe no ka hoʻomohala ʻana i nā maʻi kanesa ʻē aʻe.
Hiki ke ʻōlelo ʻia ka hoʻāʻo genetic i nā hihia e like me kēia:
- Inā he mau hōʻailona kou a i ʻole kekahi o kou ʻohana e pili ana i ka pheochromocytoma hoʻoilina a i ʻole ka maʻi paraganglioma.
- Inā he mau puʻupuʻu kou ma nā ʻāpana ʻelua o kou mau kelepa adrenal.
- Inā he ʻoi aku ma mua o hoʻokahi puʻupuʻu i loko o hoʻokahi kelepa adrenal.
- Inā he mau hōʻailona o ka piʻi ʻana o nā catecholamines i loko o ke koko.
- Inā ʻike ʻia ka pheochromocytoma ma mua o 40 mau makahiki.
Inā loaʻa i kahi hoʻokolohua genetic kahi loli gene, hiki i ke kākāʻōlelo genetic ke ʻōlelo aku e hana pū kekahi mau lālā ʻē aʻe o kou ʻohana (ʻo ka poʻe i asymptomatic akā i ka pilikia) i kēia hoʻokolohua.
He aha nā lāʻau lapaʻau no ka Pheochromocytoma?
ʻO ka lāʻau lapaʻau maikaʻi loa no kēia, ʻo ia ka wehe ʻana i ka puʻupuʻu ma ke ʻoki ʻana, inā hiki .
ʻO ke koho ʻana o ka lāʻau lapaʻau e pili ana i kekahi mau kumu:
- Ka nui o ka puʻupuʻu.
- Inā he maʻi kanesa (malignant) a i ʻole benign ) ka puʻupuʻu.
- Inā he mau hōʻailona ma muli o ka hoʻonui ʻia ʻana o nā hormones catecholamine.
- Ua kaupalena ʻia ka puʻupuʻu i hoʻokahi wahi, a ua pālahalaha paha i nā ʻāpana ʻē aʻe o ke kino? (Metastasised)
- Inā paha ua ʻike mua ʻia ka maʻi, a inā paha ua hoʻi hou mai ma hope o ka lāʻau lapaʻau mua.
Inā loaʻa iā ʻoe nā hōʻailona ma muli o ka hoʻonui ʻia o nā hormones adrenal, hiki i kāu kauka ke kuhikuhi i nā lāʻau lapaʻau e kāohi i kēlā mau hōʻailona. Eia kekahi laʻana:
- Nā lāʻau lapaʻau e mālama i ke koko ma kahi pae maʻamau, e like me nā alpha-blockers.
- Nā lāʻau lapaʻau e mālama i ka puʻuwai puʻuwai ma kahi pae maʻamau, e like me nā beta-blockers.
- Nā lāʻau lapaʻau e ālai ai i nā hopena o nā hormones i hoʻokuʻu ʻia e ka kelepa adrenal.
ʻO nā koho nui no ka mālama ʻana i ka pheochromocytoma:
- ʻoki kino
- Hoʻōla radiation
- Kemoterapia
- Lapaʻau ablation
- Lapaʻau embolization
- Hoʻōla i kuhikuhi ʻia
E hui pū, ʻoe a me kāu hui lapaʻau e hoʻoholo i ka hoʻolālā lapaʻau kūpono loa iā ʻoe.
Nā ʻano lapaʻau nui
- ʻO ke ʻoki kino:
ʻO kēia ke ʻano lapaʻau nui no ka pheochromocytoma. Ma kahi o 90% o nā ʻōpū hiki ke wehe pono ʻia ma ke ʻoki ʻana .
Hiki i kāu kauka ke ʻōlelo aku i ke ʻoki kino e wehe i kekahi a i ʻole nā ʻelua o kāu mau kelepa adrenal (adrenalectomy). I ka wā o ke ʻoki kino, e nānā ke kauka ʻoki kino i nā ʻiʻo a puni a me nā lymph node e ʻike inā ua pālahalaha ka puʻupuʻu. Inā ua pālahalaha, e wehe lākou i kēlā ʻiʻo, inā hiki.
Ma hope o ke ʻoki kino, e hoʻāʻo ʻia kou koko a i ʻole kou mimi no nā pae catecholamine. Inā hoʻi nā pae i ka maʻamau, ʻo ia hoʻi ua wehe ʻia nā hunaola pheochromocytoma āpau.
Inā wehe ʻia nā kelepa adrenal ʻelua, pono ʻoe e lawe i ka lāʻau lapaʻau hormone no ke koena o kou ola e pani i nā hormones i hana ʻia e nā kelepa adrenal.
- Hoʻōla radiation:
He lāʻau lapaʻau kēia i hoʻohana ʻia e pepehi i nā hunaola kanesa a i ʻole e kāohi iā lākou mai ka ulu ʻana. Hana ʻia kēia ma ke ʻano e hōʻino ʻole ai i nā ʻiʻo olakino e like me ka hiki.
Aia ʻelua ʻano o ka radiation therapy:
- Ka lāʻau lapaʻau radiation waho: Hoʻouna ʻia ka radiation i kahi maʻi kanesa mai kahi mīkini ma waho o ke kino.
- Lapaʻau radiation kūloko: Hoʻopaʻa ʻia kahi mea radioactive i loko o nā nila, nā hua, nā uea, a i ʻole nā catheters a hoʻokomo ʻia e ke kauka i loko a kokoke paha i kahi o ke kanesa.
ʻO ke ʻano o ka radiation therapy e pili ana i ka mea inā he kūloko ka maʻi kanesa, ʻāpana, metastatic, a i ʻole recurrent. Hoʻōla pinepine ʻia ka pheochromocytoma malignant me ka radiation therapy beam waho a/a i ʻole ka 131I-MIBG therapy. ʻO 131I-MIBG kahi mea radioactive e hoʻopili i kekahi mau cell cancer a pepehi iā lākou.
- Kemokalama:
Hoʻohana kēia i nā lāʻau lapaʻau e pepehi i nā hunaola kanesa, e kāohi iā lākou mai ka māhele ʻana a me ka hoʻonui ʻana, a i ʻole e kāohi i ka ulu ʻana o ke kanesa. Hāʻawi pinepine ʻia kēia mau lāʻau lapaʻau ma ke ʻano intravenous. ʻOiai he lāʻau lapaʻau holomua kēia, hiki ke loaʻa nā hopena ʻaoʻao.
- Hoʻōla ablation:
He lāʻau lapaʻau minimally invasive kēia. Hoʻohana ia i ka wela nui a i ʻole ke anu nui e hoʻopau ai i nā puʻupuʻu.
- ʻO ka hoʻopau ʻana i ke alapine radio: Hoʻohana ka ablation radiofrequency i nā nalu lekiō e hoʻomehana a luku i nā ʻōpū kanesa a me nā ʻōpū maʻi ʻē.
- Cryoablation: Hoʻohana i ka naikokene wai a i ʻole ke kalapona ʻokikene wai e hoʻopaʻa a luku i nā ʻōpū kanesa a me nā ʻōpū maʻi ʻē.
- Ka lāʻau lapaʻau embolization:
Ma kēia ʻano, ua ālai ʻia ke aʻa e hoʻolako ana i ke koko i ke kelepa adrenal. Hoʻōki kēia i ke kahe koko i ke kelepa, e pepehi ana i nā hunaola kanesa e ulu ana ma laila.
- Hoʻōla i kuhikuhi ʻia:
Hoʻohana kēia i nā lāʻau lapaʻau a i ʻole nā mea ʻē aʻe e hoʻouka wale i nā hunaola kanesa me ka ʻole o ka hōʻeha ʻana i nā hunaola olakino. Hoʻohana ʻia kēia lāʻau lapaʻau no ka pheochromocytoma metastatic a me ka recurrent.
Ke aʻo ʻia nei kahi mea hoʻopaʻa tyrosine kinase i kapa ʻia ʻo sunitinib no ka pheochromocytoma metastatic. Ke kāohi nei kēia mau lāʻau i ka ulu ʻana o ka maʻi puʻupuʻu.
Hiki ke pale ʻia kēia maʻi?
ʻO ka mea pōʻino, ʻaʻohe ala e pale aku ai i ka pheochromocytoma. Eia nō naʻe, inā ʻoe e pilikia ana i ka loaʻa ʻana o kēia maʻi ma muli o nā syndromes hoʻoilina a me nā genes, hiki i ke aʻo ʻana i nā genetics ke kōkua i ka nānā ʻana a me ka ʻike mua ʻana.
Inā ua loaʻa i kekahi o kou ʻohana pili (nā kaikaina, nā mākua) ka pheochromocytoma, a inā he maʻi genetic kou e like me nā mea a mākou i kūkākūkā ai ma mua (Multiple endocrine neoplasia 2 syndrome, Von Hippel-Lindau (VHL) disease, Neurofibromatosis type 1 (NF1), Hereditary paraganglioma syndrome, Carney-Stratakis dyad, Carney triad), he mea nui loa ia e kamaʻilio me kāu kauka e pili ana i ia mea.
He aha ka manawa e ola ai ma hope o ka mālama ʻana? (Prognosis)
ʻO ka nānā ʻana no ka pheochromocytoma ma ke ʻano laulā he maikaʻi loa inā mālama ʻia.Ua ʻōlelo mua mākou e hiki ke hoʻoneʻe pono ʻia ma kahi o 90% o nā ʻōpū ma ke ʻoki ʻana.
Eia nō naʻe, inā ʻaʻole mālama ʻia, hiki i kēia kūlana ke alakaʻi i nā pilikia koʻikoʻi, a hiki ke hoʻoweliweli i ke ola . Eia kekahi laʻana:
- ʻO ke cardiomyopathy
- ʻO ka maʻi puʻuwai
- Ke kahe koko i kāohi ʻole ʻia ma ka lolo (Cerebral hemorrhaging)
- Ka hōʻiliʻili ʻana o ka wai i loko o nā māmā (Pulmonary edema)
Loaʻa i kekahi mau maʻi me ka pheochromocytoma ka pilikia o ka hahau ʻana a i ʻole ka myocardial infarction.
Āhea wau e ʻike ai i ke kauka?
- Inā ua ʻike ʻia ʻoe me ka pheochromocytoma a loaʻa i kekahi mau hōʻailona pilikia, e ʻike koke i kāu kauka.
- Inā loaʻa iā ʻoe nā hōʻailona o ka pheochromocytoma, e like me ke koko kiʻekiʻe a me ke poʻo ʻeha, e kamaʻilio me kāu kauka. ʻOiai he mea kakaikahi ka pheochromocytoma, he mea nui e mālama i ke koko kiʻekiʻe.
- Inā ʻike ʻoe aia kekahi o kou mau hoahānau pili (nā kaikaina, nā mākua) i kahi maʻi genetic e like me ka 'Multiple endocrine neoplasia 2 syndrome' a i ʻole ka 'maʻi Von Hippel-Lindau (VHL)', hiki paha iā ʻoe ke loaʻa i ka pheochromocytoma kiʻekiʻe aʻe, no laila e ʻike i ke kauka e kamaʻilio e pili ana i ka hoʻāʻo genetic.
He aha nā nīnau e pono iaʻu e nīnau aku i ke kauka?
Inā ua ʻike ʻia ʻoe me ka pheochromocytoma, he mea kōkua paha ke nīnau i kāu kauka i kēia mau nīnau:
- No ke aha i loaʻa ai iaʻu ka pheochromocytoma?
- Hiki i kaʻu mau keiki a/a i ʻole nā hoahānau ke loaʻa i ka pheochromocytoma?
- He aha nā koho lapaʻau e loaʻa iaʻu?
- He aha nā hopena ʻaoʻao o nā lāʻau lapaʻau like ʻole?
- Pehea e hiki ai iaʻu ke mālama i kaʻu mau hōʻailona?
ʻO ka mea hope loa, nā mea nui e hoʻomanaʻo (Leka Lawe-Home)
ʻAe, no laila, ʻoiai he puʻupuʻu kakaikahi ka pheochromocytoma, he maʻi pinepine ia a hiki ke mālama ʻia . Eia kekahi, hiki ke holo i loko o nā ʻohana, no laila inā ʻike ʻia ʻoe a i ʻole kekahi o kou ʻohana me kēia maʻi, he mea nui e loaʻa ka hoʻāʻo genetic. Hiki i kēia ke kōkua i ka hoʻoholo ʻana inā pilikia ʻoe no nā pilikia olakino ʻē aʻe.
E hoʻomanaʻo, inā he mau nīnau kāu e pili ana i kou pilikia o ka loaʻa ʻana o ka pheochromocytoma a i ʻole e pili ana i kēia maʻi, mai makaʻu e kamaʻilio me kāu kauka. Eia lākou e kōkua iā ʻoe. E noho olakino!
ʻO Pheochromocytoma , ke kelepa adrenal, catecholamines, ke koko kiʻekiʻe, ka ʻeha poʻo, ka hou ʻana, ka puʻupuʻu, ka ʻōnaehana endocrine
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