Ua lohe anei ʻoe i ka maʻi diabetes Type 1? He kūlana kēia kahi e hele hewa ai ka ʻōnaehana pale o ko mākou kino a hoʻouka i nā hunaola hana insulin i loko o ka pancreas. He mea hopohopo iki kēia. Akā me ka holomua o ka ʻepekema lapaʻau, ke kū mai nei nā ala hou e hoʻokele ai i kēia mau kūlana. ʻO kekahi o ia mau manaʻolana hou he lāʻau lapaʻau i kapa ʻia ʻo Teplizumab. ʻO kēia kāna hana, hoʻopaneʻe ia i ka hoʻomaka ʻana o ka maʻi diabetes Type 1. No laila e kamaʻilio kākou e pili ana i kēia i kēia lā ma ke ʻano maʻalahi hiki iā ʻoe ke hoʻomaopopo.
He aha ke ʻano lāʻau lapaʻau ʻo Teplizumab?
I ka ʻōlelo maʻalahi, ʻo Teplizumab kahi lāʻau lapaʻau e hiki ai i nā poʻe i pilikia i ka loaʻa ʻana o ka maʻi diabetes Type 1 ke hoʻopaneʻe i ka hoʻomaka ʻana o ka maʻi no kekahi mau makahiki. ʻAʻole ia he lāʻau lapaʻau no ka maʻi diabetes, akā hoʻopaneʻe ia i ka hoʻomaka ʻana o ka maʻi. He mea nui kēlā, ʻeā?
No ka hui i kapa ʻia ʻo Monoclonal Antibody kēia lāʻau. Mai hopohopo ke lohe ʻoe i kēlā inoa. E noʻonoʻo e hele hewa ana nā koa (antibodies) i loko o ka ʻōnaehana pale o ko kākou kino a hoʻomaka e hoʻouka i kā kākou mau cell maikaʻi ponoʻī. I kēlā manawa, no ka hoʻomalu ʻana i kēia mau koa e hana hewa ana, ʻo kekahi ʻano protein i hana kūikawā ʻia ma ka hale hana i kapa ʻia ʻo Monoclonal Antibody. ʻO ka mea a Teplizumab e hana ai, ʻo ia ke kāohi iki i ka hana a ka ʻōnaehana pale e hoʻouka hewa ana i nā cell e hana ana i ka insulin. No laila, ua lohi ka ulu ʻana o ka maʻi diabetes.
Loaʻa pinepine kēia lāʻau lapaʻau ma ka mākeke ma lalo o ka inoa inoa ʻo Tzield .
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau
He mea nui loa kēia. Ma mua o kou hoʻomaka ʻana i ka mālama ʻana me Teplizumab, he mea nui e haʻi i kāu kauka i kēia ʻike. Hoʻopilikia pololei kēia mau mea i ka holomua o ka mālama ʻana a me kou palekana.
| Ke kūlana āu e pono ai e hōʻike | No ke aha he mea nui kēlā? |
|---|---|
| Ke kūlana maʻi o kēia manawa (e like me ke kuni, ke anu, ka ʻū) | Ma muli o ka hōʻemi ʻana o kēia lāʻau lapaʻau i ka hana o ka ʻōnaehana pale maʻi, hiki i kahi maʻi ke lilo i mea ʻino aʻe. |
| Maʻi akepaʻa | Ma muli o ke koʻikoʻi o ke akepaʻa no ke kaʻina hana o ka wehe ʻana i nā lāʻau lapaʻau mai ke kino, pono ʻoe e hoʻomaopopo i kāu kauka inā loaʻa iā ʻoe kekahi mau pilikia o ke akepaʻa. |
| Ua emi nā ʻāpana koko (nā hunaola koko ʻulaʻula, nā hunaola koko keʻokeʻo, nā platelets) | Hiki i kēia lāʻau lapaʻau ke hoʻemi hou aku i nā ʻāpana koko, no laila he mea weliweli inā ua haʻahaʻa mua nā pae. |
| He lāʻau pale i hala koke aku nei a i ʻole e hiki mai ana | Hiki i nā lāʻau pale ola ke launa pū me kēia lāʻau. No laila, e ʻoluʻolu e hāʻawi mai i kahi wehewehe piha o ka lāʻau pale. |
| Nā maʻi ʻaleka i nā lāʻau lapaʻau, nā meaʻai, a i ʻole nā mea ʻē aʻe | He mea nui kēia e ʻike inā he maʻi ʻoe iā Teplizumab a i ʻole kekahi o kāna mau mea hoʻohui. |
| Inā ʻoe e ho'āʻo nei e hāpai a hāpai paha | ʻAʻohe ʻikepili piha e pili ana i ka palekana o kēia lāʻau lapaʻau i ka wā hāpai, no laila pono ʻoe e kamaʻilio me kāu kauka e pili ana i kēia. |
| Inā he makuahine hānai ʻoe | He mea nui kēia ʻike e hoʻoholo ai inā hele ka lāʻau lapaʻau i ka pēpē ma o ka waiū umauma. |
Pehea e hāʻawi ʻia ai kēia lāʻau i ke kino?
ʻAʻole ʻo Teplizumab kahi lāʻau lapaʻau hiki iā ʻoe ke lawe i ka home a hoʻohana.
- Hāʻawi ʻia kēia ma ke ʻano he intravenous (IV) infusion .
- Hana ʻia ia ma kahi haukapila a i ʻole ke keʻena lapaʻau ma lalo o ka nānā ʻana a kahi hui lapaʻau.
- ʻO ka maʻamau, hāʻawi ʻia kēia lāʻau i kēlā me kēia lā no 14 mau lā.
- Ma mua o kou hoʻomaka ʻana i ka lāʻau lapaʻau, e hāʻawi ʻia ʻoe i kahi pepa kūikawā (MedGuide) me nā kikoʻī e pili ana i kēia lāʻau lapaʻau. E heluhelu pono mau.
- Hiki ke hāʻawi ʻia kēia lāʻau lapaʻau i nā keiki ma luna o 8 mau makahiki ma lalo o kekahi mau kūlana. Eia nō naʻe, aia kekahi mau mea kūikawā e pono e makaʻala. E kamaʻilio me kāu kauka e pili ana i kēia.
Mea nui:Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau lapaʻau, e kāhea koke aku i ke Kikowaena ʻIke Poisons National ma ka Halemai Lahui ʻo Colombo a i ʻole e hele i ka Emergency Treatment Unit (ETU) o ka haukapila kokoke loa.
He aha inā e hala iaʻu kahi mahele o ka lāʻau lapaʻau?
He mea nui loa ka lawe ʻana i kēlā me kēia mahele o kēia lāʻau lapaʻau i ka manawa kūpono. Inā ʻaʻole hiki iā ʻoe ke hele i kāu lāʻau lapaʻau i hoʻonohonoho ʻia, e kāhea koke i kāu hui mālama ola.
Nā mea e noʻonoʻo ai i ka wā o ka mālama ʻana
E nānā pono ana kāu hui lapaʻau iā ʻoe i kou wā e lawe ana i kēia lāʻau.
- Nā hoʻāʻo koko: Pono ʻoe e hana i nā hoʻāʻo koko maʻamau. E nānā kēia i nā pae o nā mea e like me nā hunaola koko keʻokeʻo, nā hunaola koko ʻulaʻula, a me ka hana o ke akepaʻa i loko o kou koko.
- Ka pilikia o ka maʻi: Hoʻemi kēia lāʻau lapaʻau i ka hana o ka ʻōnaehana pale, kahi e hoʻonui ai i kou pilikia o ka loaʻa ʻana o nā maʻi. Inā ʻike ʻoe i nā hōʻailona e like me ke kuni, ke anu, ka ʻāʻī ʻeha, a i ʻole ke kuni, mai hoʻōla ponoʻī a kāhea koke i kāu kauka. He manaʻo maikaʻi nō hoʻi e hōʻemi i ka hele ʻana i nā wahi i maʻi ai ka poʻe i kēia manawa.
- Nā lāʻau pale: He mea nui loa kēia. Ma waena o 6 a me 52 mau pule ma hope o ka lawe ʻana iā Teplizumab, hiki i kou kino ke pane maikaʻi ʻole i nā lāʻau pale āu e loaʻa ai. No laila, inā pono ʻoe e loaʻa i kahi lāʻau pale, e haʻi i kāu kauka ua lawe ʻoe iā Teplizumab. Pono paha ʻoe e loaʻa i nā dosis hoʻonui a hoʻololi paha i kāu papa hana lāʻau pale.
Nā hopena ʻaoʻao e hiki mai ana ma muli o ka lāʻau lapaʻau
E like me nā lāʻau lapaʻau āpau, hiki iā Teplizumab ke hana i nā hopena ʻaoʻao. He koʻikoʻi kekahi, aʻo kekahi he mea maʻamau.
| Nā hopena ʻaoʻao e pono e hōʻike koke ʻia i ke kauka | |
|---|---|
| Ka hopena ʻaoʻao | Wehewehena |
| Nā hopena maʻi ʻaleka | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe, ke alelo a i ʻole ka puʻu. |
| ʻO ka maʻi hoʻokuʻu Cytokine (CRS) | He maʻi koʻikoʻi kēia i hoʻokumu ʻia e ka hoʻouka koke ʻana o ka ʻōnaehana pale. Hiki i nā hōʻailona ke komo pū me ke kuni, ke anu, ka nāwaliwali, ka ʻeha poʻo, ka poniuniu, ka paʻakikī o ka hanu ʻana, a me ka wikiwiki o ka puʻuwai . |
| Nā hōʻailona o ka maʻi | Kuni, anu, ʻū, ʻeha ka puʻu. |
| Nā hopena ʻaoʻao ʻaʻole i koʻikoʻi pinepine (akā pono e hōʻike i ke kauka inā hoʻomau lākou) | |
| Ka maʻi pākī | Ka hoʻonui ʻana o ka ʻōpū. |
| ʻEha poʻo | ʻEha poʻo. |
| Ka luaʻi | Manaʻo e luaʻi ana. |
| ʻŌhū ʻili | Nā pehu liʻiliʻi a i ʻole ka ʻulaʻula ma ka ʻili. |
ʻAʻole i loko o kēia papa inoa nā hopena ʻaoʻao āpau. Inā loaʻa iā ʻoe kekahi mea ʻē, e ʻoluʻolu e kelepona i kāu kauka no ka ʻōlelo aʻoaʻo lapaʻau.
Leka Lawe-Home
- ʻAʻole ʻo Teplizumab he lāʻau lapaʻau no ka maʻi diabetes Type 1, akā he lāʻau ia e hiki ke hoʻopaneʻe nui i kona hoʻomaka ʻana.
- He lāʻau lapaʻau kūikawā kēia i hāʻawi ʻia i kahi aʻa koko ma ka haukapila, ma lalo o ka mākaʻikaʻi a ke kauka.
- Ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau, e hāʻawi i kāu kauka i ka wehewehe piha no kou mau kūlana olakino āpau, nā lāʻau lapaʻau āu e lawe nei, a ʻoi aku hoʻi i nā lāʻau pale i loaʻa iā ʻoe.
- I ka wā o ka mālama ʻanaE makaʻala loa i nā hōʻailona o ka maʻi e like me ke kuni, ka ʻū, a i ʻole ka Cytokine Release Syndrome (CRS) . Inā loaʻa kekahi o kēia mau mea, e hoʻomaopopo koke i kāu kauka.
- Inā he mau nīnau kāu e pili ana i kēia lāʻau lapaʻau, ʻo ke kanaka maikaʻi loa e nīnau aku ai ʻo ia kāu kauka . Mai hopohopo e pili ana i ka nīnau ʻana i nā poʻe ʻē aʻe.
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