E aʻo kākou e pili ana i ka lāʻau Verzenio, ka mea i hāʻawi ʻia i ka wā e laha ai ke kanesa o ka umauma? (Metastatic Breast Cancer)

Ke haʻi aku ke kauka iā ʻoe ua laha ka maʻi ʻaʻai umauma i nā ʻāpana ʻē aʻe o ke kino, ʻo ia hoʻi, ua lilo ia i 'metastatic', he mea maʻamau ke manaʻo nui i ka makaʻu a me ka hopohopo. Eia nō naʻe, me ka holomua o ka lāʻau lapaʻau hou, aia nā lāʻau lapaʻau kūpono loa no ia mau hihia i kēia lā. ʻO Verzenio kekahi lāʻau lapaʻau e lawe mai ana i ka manaʻolana. No laila i kēia lā, e kamaʻilio pōkole kākou e pili ana i kēia lāʻau i kapa ʻia ʻo Verzenio, pehea e hana ai, a me nā mea e makaʻala ai i ka wā e hoʻohana ana.

Pehea e hana ai ʻo Verzenio i loko o ke kino?

I ka ʻōlelo maʻalahi, ʻo Verzenio kahi lāʻau lapaʻau no kahi papa o nā lāʻau lapaʻau i kapa ʻia ʻo "kinase inhibitors." E noʻonoʻo e like me he mau enzymes i loko o ko kākou kino e hana ana e like me nā "ʻelele" e lawe ana i ka ʻike i waena o nā cell. ʻO kēia nā mea a mākou e kapa nei he "kinases." Hana ʻia nā cell cancer me kēia mau ʻelele kūikawā e haʻi iā lākou e māhele a ulu koke.

Hana ʻo Verzenio ma ke ālai ʻana i ka hana o nā ʻelele i kapa ʻia ʻo `cyclin-dependent kinases 4 a me 6 (CDK4 a me CDK6)`, ka mea e hoʻouna i nā hōʻailona i nā cell kanesa e ulu. I mea e pololei ai, ālai ia i kēlā mau leka i ka hapalua o ka huakaʻi. Ma kēia ʻano, ke pau ka hana ʻana o nā enzyme CDK4 a me CDK6, nalowale nā ​​​​cell kanesa i ka hōʻailona e māhele a ulu. ʻO ka hopena , ua pau a lohi paha ka ulu ʻana o nā cell kanesa . Kōkua pū kēia i ka hoʻēmi ʻana i nā puʻupuʻu.

He aha nā ʻano maʻi ʻaʻai umauma e hoʻohana ʻia ai ʻo Verzenio?

ʻAʻole hāʻawi ʻia kēia lāʻau lapaʻau no nā ʻano maʻi ʻaʻai umauma āpau. Hoʻohana kūikawā ʻia no:

• ʻO ka mea loaʻa hormone (HR)-maikaʻi a me
• ʻO ka mea loaʻa ulu ulu epidermal kanaka 2 (HER2)-maikaʻi ʻole

Hoʻohana ʻia ia no kekahi ʻano maʻi ʻaʻai umauma i kapa ʻia ʻo ka maʻi ʻaʻai umauma metastatic. Hāʻawi ʻia nō hoʻi ia i ka wā i pālahalaha ai ke kanesa ma waho o ka umauma i nā ʻāpana ʻē aʻe o ke kino, e like me ke akepaʻa, nā māmā, a i ʻole nā ​​iwi.

I kekahi manawa hāʻawi pū ʻia kēia lāʻau lapaʻau me nā lāʻau hormonal ʻē aʻe. Eia nō naʻe, i nā hihia i pālahalaha ai ke kanesa a ʻaʻole i pane ka maʻi i ka chemotherapy a me nā lāʻau hormonal, hiki ke hāʻawi wale ʻia ʻo Verzenio. Hoʻoholo ʻia kēia e ke kauka nāna ʻoe e mālama nei.

Pehea e lawe ai iā Verzenio? He aha kaʻu e pono ai e makaʻala?

He pila ʻo Verzenio. Pono ʻoe e makaʻala i kēia mau mea i ka wā e hoʻohana ai.

• Pono ʻoe e lawe i kēia pila i ʻelua manawa i ka lā .
• Hiki iā ʻoe ke lawe ma mua a ma hope paha o ka ʻai ʻana, akā e hoʻāʻo e lawe iā ia i ka manawa like i kēlā me kēia lā .
• Pono e ale holoʻokoʻa ʻia ka papa. Mai wāwahi, kuʻi, a nau paha.
• Mai lawe i nā pila haki, ʻoki, a i ʻole nā ​​​​pala i hōʻino ʻia.I kēlā manawa, e kāhea i kāu kauka a haʻi iā ia e pili ana i ia mea.
• Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka lāʻau lapaʻau, e hōʻalo i kēlā mahele lāʻau. Mai lawe i kahi pila keu . E lawe i ka pila aʻe i ka manawa i hoʻonohonoho ʻia.

E aʻo aku kāu kauka iā ʻoe e hoʻomau i ka lawe ʻana i kēia lāʻau lapaʻau a hiki i ka wā e kaohi ʻia ai kou maʻi ʻaʻai a i ʻole a hiki i kou loaʻa ʻana o nā hopena ʻino. Inā loaʻa iā ʻoe kekahi mau hopena ʻino, hiki i kāu kauka ke hoʻoholo e hōʻemi i kāu lāʻau, e hoʻōki i ka lawe ʻana no kekahi manawa, a i ʻole e hoʻōki loa iā ia.

Pehea ka maikaʻi o Verzenio? (Nā hopena o ka hoʻāʻo lapaʻau)

Ua ʻāpono ʻia kēia lāʻau lapaʻau ma muli o nā hopena o kekahi mau hoʻokolohua lapaʻau i kūleʻa loa. E nānā koke kākou i nā hopena mai kēlā mau hoʻokolohua.

Pehea e nānā ai ke kauka i ka holomua o ka lāʻau lapaʻau?

Ke hoʻomaka ʻoe e lawe i ka lāʻau lapaʻau, e nānā mau ke kauka iā ʻoe.

• Nā Scan: Hana pinepine ʻia kahi scan ma kahi o 6 mau pule ma hope o ka hoʻomaka ʻana i ka lāʻau lapaʻau e ʻike ai pehea e pane ai ke kanesa i ka lāʻau lapaʻau.
• Nā Hoʻāʻo Koko: He mea nui loa kēia. Nānā mau ʻia nā pae o nā cell i loko o kou koko, e like me nā cell koko keʻokeʻo, nā neutrophils, a me nā platelets, e hōʻoia i ka hana palekana o ka lāʻau lapaʻau no kou kino.

Pehea e mālama ai i nā hopena ʻaoʻao inā loaʻa lākou?

He mea maʻamau nā hopena ʻaoʻao me nā lāʻau lapaʻau maʻi kanesa. ʻO ka mea nui loa, ʻo ia ke haʻi aku i kāu kauka e pili ana i nā loli a i ʻole ka ʻoluʻolu ʻole āu e manaʻo ai, ʻoiai inā he liʻiliʻi wale nō.

• Nā hoʻāʻo koko maʻamau: Hiki iā Verzenio ke hoʻemi i nā hunaola koko keʻokeʻo i kekahi manawa. Ua kapa ʻia kēia he "neutropenia." Hiki i kēia ke alakaʻi i nā maʻi koʻikoʻi. No laila he mea nui e loaʻa nā hoʻāʻo koko a pau a kāu kauka e kauoha ai.
• ʻŌpū ʻeha: He mea maʻamau ka luaʻi, ka luaʻi ʻana, a me ka maʻi pākī. Hiki ke hoʻomalu ʻia kēia mau mea ma ka ʻai ʻana i nā meaʻai momona ʻole, a me ka ʻai ʻana i nā meaʻai liʻiliʻi ma mua o nā meaʻai nui. Eia nō naʻe, inā koʻikoʻi kou maʻi pākī, pono ʻoe e haʻi koke i kāu kauka . E hāʻawi ʻo ia iā ʻoe i ka ʻōlelo aʻoaʻo e pono ai.
• Nā hopena koʻikoʻi ʻē aʻe: Inā ʻike ʻoe i kekahi mau hōʻailona o ke koko ʻaʻa (pehu ʻana a i ʻole ka palapū ʻana i kahi wāwae) e hoʻopilikia ai i kou mau māmā, e like me ke kuʻi ʻana, ka paʻakikī o ka hanu ʻana, a i ʻole ka pōkole o ka hanu ʻana, pono ʻoe e hoʻomaopopo koke i kāu kauka.

Aia kekahi mau mea kūikawā ʻē aʻe e pono e ʻike?

ʻAe, aia kekahi mau mea hou aʻe.

• E ʻai i ka pomelo, ʻaʻole ka wai huaʻai: Hoʻōki ka pomelo i ke kino mai ka wāwahi ʻana iā Verzenio. Hiki i kēia ke hoʻonui i nā pae o ka lāʻau lapaʻau i loko o ke kino me ke kumu ʻole, e hoʻonui ana i nā hopena ʻaoʻao.
• Kekahi mau lāʻau lapaʻau: ʻO ka lawe ʻana i nā lāʻau antifungal e like me ketoconazole me kēia lāʻau lapaʻau hiki ke hana i nā hopena ʻino. No laila, e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe ai (me nā huaora a me nā mea hoʻohui) .
• Nā maʻi ʻē aʻe:Inā loaʻa iā ʻoe nā pilikia olakino ʻē aʻe, e like me ka maʻi akepaʻa, pono paha e hoʻoponopono ʻia kāu dosage Verzenio. E kamaʻilio me kāu kauka e pili ana i kou mōʻaukala olakino piha.