E aʻo kākou e pili ana i ka IgA Nephropathy (Maʻi Berger), ka mea e hōʻino malū i kou mau puʻupaʻa.

Ua ʻike anei ʻoe i ka wā e loaʻa ai iā ʻoe ke anu, lilo kou mimi i ke kala tī? A i ʻole ke ʻike nei ʻoe he nui ka huʻa o kāu mimi? ʻOiai he nui ka poʻe e manaʻo nei he mau mea maʻamau kēia, ʻo ia paha ka hōʻailona mua e hewa ana kekahi mea me kou mau puʻupaʻa. I kēia lā e kamaʻilio mākou e pili ana i kahi maʻi i kapa ʻia ʻo IgA Nephropathy, kahi e hoʻopilikia mālie ai i ko mākou kino a he mea ia i lohe ʻole ʻia e ka poʻe he nui.

I ka ʻōlelo maʻalahi, he aha ka IgA Nephropathy?

He maʻi kēia e hōʻino ana i nā puʻupaʻa ma muli o kahi pilikia me ko kākou ʻōnaehana pale kino ponoʻī. I ka pololei, he maʻi autoimmune kēia.

E noʻonoʻo i ko kākou ʻōnaehana pale ma ke ʻano he pūʻali koa e pale aku ana i kahi ʻāina. He ʻano koa kūikawā ko kēia pūʻali koa, a mākou e kapa nei he mau antibodies . ʻO kā lākou hana ka ʻimi a luku i nā ʻenemi, e like me nā virus a me nā bacteria, e komo i loko o ke kino. ʻO Immunoglobulin A, a i ʻole IgA, kekahi o ia mau antibody kūikawā.

ʻO ke kanaka me ka IgA Nephropathy he loli iki, a hemahema paha, i kekahi o nā antibodies IgA i hana ʻia i loko o ke kino. Ma muli o kēia, ʻaʻole hiki i nā mea pale ʻē aʻe i loko o kā mākou ʻōnaehana pale ponoʻī ke ʻike i kēia IgA ʻē. Manaʻo lākou he ʻenemi ia mai waho. No laila, hoʻouka lākou i kēia IgA ʻē a hui pū e hana i nā puʻupuʻu nui.

ʻO kēia pōʻino e pale aku ai i nā puʻupaʻa mai ka kānana pono ʻana i ke koko. ʻO kēia ke kumu o ka nalowale ʻana o ke kaulike kemika o ke kino. Inā ʻaʻole mālama ʻia, hiki i kēia pōʻino ke holomua i ka maʻi puʻupaʻa hope loa.

Aia kekahi kumu kikoʻī no kēia maʻi?

ʻAʻole i loaʻa i nā kānaka ʻepekema ke kumu kikoʻī o kēia maʻi. Akā, ʻaʻole ia he maʻi laha. Ua manaʻoʻiʻo ʻia he pilina hoʻoilina kona. ʻO ia hoʻi, inā loaʻa i kekahi o kou ʻohana, he wahi liʻiliʻi kou e loaʻa ai.

Eia kekahi, hiki i kekahi mau kūlana olakino ke lilo i 'mea hoʻoulu' no kēia e hoʻomaka.

ʻOiai hiki ke ulu kēia maʻi i kēlā me kēia makahiki, ʻike pinepine ʻia nā hōʻailona i ka poʻe ma lalo o 40 makahiki. ʻOi aku ka pālua o ka loaʻa ʻana o ia ma mua o nā wahine i nā kāne.

E ʻike pono kākou i nā hōʻailona.

ʻO ka pilikia nui me kēia maʻi, ʻaʻole ia e hōʻike i nā hōʻailona i nā pae mua. ʻO ia ke kumu i ʻike ʻole ai ka poʻe he nui ua loaʻa iā lākou kēia maʻi.

Eia nō naʻe, ʻo ka hōʻailona nui a maopopo loa i kekahi poʻe, ʻo ia ke koko i loko o ka mimi (hematuria) ke loaʻa iā lākou kahi mea e like me ke anu, ka maʻi palū, a i ʻole ka maʻi ʻāʻī . Hiki ke ʻike ʻia ka mimi e like me ke kala tī, ke kala kola, a i ʻole ka ʻulaʻula. Ke pau ka maʻi, hoʻi ka mimi i kona kala maʻamau.

ʻO kekahi hōʻailona nui ʻē aʻe, ʻo ia ka mimi huʻa . Ma muli kēia o ka puka ʻana o ka protein i loko o ka mimi (proteinuria).

Ma waho aʻe o kēia mau mea, aia kekahi mau hōʻailona ʻē aʻe:

• Ka pehu ʻana ma nā wāwae, ʻoi aku hoʻi nā kuʻekuʻe wāwae.
• Ke koko kiʻekiʻe (Hypertension).
• Inā hoʻomau ka maʻi no ka manawa lōʻihi, e ʻike ʻia paha nā hōʻailona o ka hāʻule ʻana o ka puʻupaʻa.

Pehea ʻoe e ʻike ai i kēia, e Kauka?

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​e hana mua kāu kauka i kahi hoʻāʻo mimi e nānā i ke koko a i ʻole ka protein i loko o ka mimi. Eia nō naʻe, no ka mea hiki ke ʻike ʻia kēia mau mea i nā maʻi puʻupaʻa ʻē aʻe he nui, ʻaʻole hiki iā ia wale nō ke hōʻoia i ka IgA Nephropathy.

Mai hopohopo ke lohe ʻoe i kēia. He hoʻāʻo maʻamau kēia i hana ʻia ma ka haukapila. E hoʻomāno ke kauka i kou kua, e hoʻokomo i kahi nila lahilahi loa i loko o kou puʻupaʻa, a hoʻohana i kahi scanner e kiʻi i ke kiʻi o kou puʻupaʻa.Lawe ʻia kahi ʻāpana liʻiliʻi loa o ka ʻiʻo. A laila nānā ʻia ma lalo o kahi microscope e ʻike inā he mau puʻupuʻu IgA a me ka nui o ka pōʻino i hana ʻia i ka puʻupaʻa. ʻAʻole wale kēia hoʻāʻo e hōʻoia i ka maʻi, akā kōkua pū kekahi i ke kauka e hoʻoholo i ka lāʻau lapaʻau maikaʻi loa nāu.

Nā ʻano lapaʻau a me ka hoʻokele

ʻAʻohe lāʻau lapaʻau no kēia maʻi i kēia manawa. Akā, mai hopohopo! Aia nā lāʻau lapaʻau kūpono loa i kēia manawa e hiki ke kāohi i ka maʻi, hōʻemi i ka hōʻino ʻana i nā puʻupaʻa, a kōkua iā ʻoe e ola i ke ola olakino a lōʻihi.

ʻO nā pahuhopu nui o ka mālama ʻana:

• Ke kāohi nei i ke koko.
• ʻO ka hoʻemi ʻana i ka hoʻokuʻu ʻana o ka protein i loko o ka mimi.
• Ke hoʻolohi nei i ka hōʻino ʻia ʻana o nā puʻupaʻa.

No kēia, hiki i kāu kauka ke kuhikuhi iā ʻoe i nā lāʻau lapaʻau e like me:

• Nā lāʻau lapaʻau koko: Hoʻohana pinepine ʻia nā lāʻau lapaʻau e like me nā ACE inhibitors a me nā ARB no kēia. ʻAʻole wale kēia e kaohi i ke koko, akā kōkua pū kekahi i ka pale ʻana i nā puʻupaʻa.
• Nā lāʻau lapaʻau e kāohi ana i ka maʻi pale: Hiki ke hāʻawi ʻia nā lāʻau steroid e like me Prednisone a i ʻole nā ​​​​lāʻau lapaʻau hou e like me Nefecon e hōʻemi i ka mumū i loko o nā puʻupaʻa.
• Nā lāʻau lapaʻau hou i hoʻolauna ʻia: ʻO nā lāʻau lapaʻau hou e like me Sparsentan (Filspari) a me Iptacopan (Fabhalta) e kōkua i ka pale ʻana i ka hana o nā puʻupaʻa ma ka hōʻemi ʻana i ka hoʻokuʻu ʻia ʻana o ka protein i loko o ka mimi.
• Diuretics: Inā he pehu i loko o ke kino, kōkua kēia mau lāʻau lapaʻau e hoʻopau i ka wai keu ma o ka mimi.
• Nā lāʻau hoʻohaʻahaʻa kolesterol: Loaʻa paha i kekahi poʻe ke kiʻekiʻe o ka cholesterol. Ua kuhikuhi ʻia nā lāʻau lapaʻau e like me nā statins no kēia.

He mea nui loa nā hoʻololi ʻana i ke ʻano o ka nohona

Ma waho aʻe o ka lāʻau lapaʻau, hiki i nā hoʻololi liʻiliʻi i kou nohona ke kōkua nui i ka pale ʻana i kou mau puʻupaʻa.

• E hōʻemi i ka ʻai ʻana i ka paʻakai: E hōʻemi i ka nui o ka paʻakai i kāu meaʻai. E pale i nā meaʻai i hoʻopaʻa ʻia a me nā mea ʻono hana. He nui ka paʻakai i loko o kēia mau mea.
• Kaohi i ka protein: E kamaʻilio me kāu kauka a meaʻai meaʻai paha e hoʻoholo i ka nui kūpono o ka protein nāu. ʻO ka ʻai nui ʻana i ka protein e hoʻokau i ke kaumaha hou aʻe ma kou mau puʻupaʻa.
• Nā waikawa momona Omega-3: He manaʻo maikaʻi nā mea hoʻohui aila iʻa. Eia nō naʻe, e ʻoluʻolu e nīnau i kāu kauka ma mua o ka lawe ʻana i kekahi mau mea hoʻohui.
• E pale i nā lāʻau hoʻomaha ʻeha: Mai lawe i nā lāʻau hoʻomaha ʻeha e like me NSAID (e.g. Ibuprofen, Diclofenac) me ke aʻo ʻole a kāu kauka. Hiki i kēia ke hōʻeha i kou mau puʻupaʻa.
• Hōʻalo i ka puhipaka: Hoʻemi ka puhipaka i ke kahe o ke koko i nā puʻupaʻa a hōʻemi pū i ka pono o nā lāʻau lapaʻau koko.
• E nānā pinepine i kou kaomi koko: E ana a hoʻopaʻa i kou kaomi koko ma ka home.