Koj cov ntshav puas siab? Cia peb tham txog Thrombocytosis!

Koj puas tau kuaj pom tias koj cov ntshav muaj cov ntshav platelets ntau? Los yog puas muaj ib tug neeg koj paub muaj tus mob no? Nws yog ib qho ib txwm muaj uas koj yuav ntxhov siab me ntsis thaum koj hnov ​​​​​​ib yam dab tsi zoo li no. Tab sis tsis txhob txhawj, hnub no peb yuav tham txog tus mob no hu ua Thrombocytosis hauv txoj kev yooj yim uas koj tuaj yeem nkag siab.

Thrombocytosis yog dab tsi? Hais yooj yim xwb...

Hais yooj yim xwb, thrombocytosis yog thaum koj muaj cov platelets ntau dhau hauv koj cov ntshav. Tam sim no koj yuav nug tias, "Platelets yog dab tsi?" Qhov ntawd yog ib lo lus nug tseem ceeb heev!

Cov ntshav platelets yog ib hom qe ntshav me me uas pom muaj nyob hauv peb cov ntshav. Lawv lub luag haujlwm tseem ceeb yog tiv thaiv kev los ntshav thaum muaj kev los ntshav, xws li thaum muaj qhov txhab. Lawv ua haujlwm zoo li lub pas dej me me.

Tiam sis yog tias cov ntshav platelets ntau dhau lawm ces yuav ua li cas? Koj cov ntshav yuav tuab thiab nplaum. Qee zaum mob hnyav, cov ntshav platelets ntau dhau no yuav ua rau cov ntshav txhaws hauv cov hlab ntsha. Qhov no yuav ua rau muaj kev pheej hmoo ntawm cov mob xws li mob stroke lossis mob plawv nres .

Txawm li cas los xij, tsis yog txhua tus neeg mob Thrombocytosis muaj kev phom sij sib npaug. Qhov hnyav ntawm tus mob, thiab seb koj puas xav tau kev kho mob lossis tsis xav tau, nyob ntawm seb ua rau muaj li cas.

Muaj ob hom thrombocytosis tseem ceeb:

Yog, cov kws kho mob tau txheeb xyuas ob hom mob no tseem ceeb. Cia peb tham txog qhov ntawd me ntsis.

1. Kab mob ntshav txhaws tseem ceeb (ET) lossis kab mob ntshav txhaws thawj zaug

Qhov no yog ib qho mob ntshav tsis tshua muaj. Nws tshwm sim thaum koj cov pob txha - lub Hoobkas ntshav hauv koj cov pob txha - tsim cov platelets ntau dhau. Xav txog nws, feem ntau ntawm cov ntshav hauv peb lub cev yog tsim los ntawm cov pob txha no. Ib tug neeg uas muaj cov ntshav txhaws tseem ceeb muaj cov platelets ntau dhau vim muaj qhov tsis zoo hauv cov txheej txheem tsim cov ntshav no.

Tus mob no, hu ua ET (Essential Thrombocythemia) , yog suav tias yog tus kab mob uas pom ntau tshaj plaws hauv pawg ntshav hu ua Myeloproliferative Neoplasm (MPN) .

2. Kev Mob Thrombocytosis Los Yog Kev Mob Thrombocytosis Thib Ob

Qhov no yog hom mob Thrombocytosis uas feem ntau tshwm sim. Qhov no yog thaum koj lub cev tsim cov ntshav platelets ntau dua los teb rau lwm yam mob, kev kis kab mob, kev raug mob, kev phais, lossis kev tshem tawm ntawm lub po. Hais yooj yim, koj lub cev teb rau lwm yam thiab ua rau nws cov ntshav platelets ntau ntxiv. Qhov noCov kab mob reactive thrombocytosis feem ntau yog ib ntus xwb, uas txhais tau tias thaum qhov ua rau muaj teeb meem raug daws lawm, cov ntshav platelet suav rov qab mus rau qhov qub.

Leej twg thiaj muaj mob thrombocytosis?

Feem ntau cov neeg uas muaj hnub nyoog tshaj 60 xyoo raug kuaj pom tias muaj tus mob no. Tsis tas li ntawd xwb, muaj ib hom mob hu ua Essential Thrombocythemia (ET) uas cov poj niam raug kuaj pom tias muaj ob npaug ntau dua li cov txiv neej.

Dab tsi yog cov ua rau muaj thrombocytosis?

Cov laj thawj rau ob hom uas peb tau tham ua ntej kuj txawv.

Cov Ua Rau Muaj Kab Mob Ntshav Tseem Ceeb (ET)

Kab mob ntshav txhaws tseem ceeb (Essential Thrombocythemia - ET) yog ib yam mob uas tau los ntawm noob caj noob ces. Nws tsis yog ib yam dab tsi uas koj yug los nrog. Nws yog tshwm sim los ntawm kev hloov pauv, lossis kev hloov pauv, hauv qee cov noob caj noob ces uas cuam tshuam nrog kev tsim cov ntshav txhaws. Qhov no ua rau koj cov pob txha tsim cov ntshav txhaws ntau dhau.

Ntau tshaj ib nrab ntawm cov neeg uas muaj tus kab mob Essential Thrombocythemia (ET) muaj kev hloov pauv hauv cov noob caj noob ces JAK2 . Kev hloov pauv hauv cov noob caj noob ces CALR lossis MPL kuj yog ib qho uas pom ntau.

Cov kws tshawb fawb tseem tsis tau paub meej tias yog dab tsi ua rau muaj cov kev hloov pauv ntawm cov noob caj noob ces no, tab sis kev tshawb fawb txuas ntxiv mus.

Cov Ua Rau Mob Thrombocytosis

Hom no tshwm sim vim tias koj lub cev tsim cov platelets ntau dua los teb rau ntau yam mob. Los yog, qee zaum, nws kuj tseem tuaj yeem yog vim tias cov platelets qub sib sau ua ke es tsis raug rhuav tshem ntawm tus nqi ib txwm.

Nov yog qee yam uas ua rau muaj Reactive Thrombocytosis :

• Kab mob ntshav tsis txaus , tshwj xeeb tshaj yog cov kab mob ntshav tsis txaus.
• Lwm yam kab mob ntshav.
• Qee hom mob qog noj ntshav .
• Cov kab mob, xws li mob ntsws .
• Cov mob o - cov mob uas ua rau mob hauv lub cev, xws li mob pob qij txha rheumatoid.
• Kev raug mob .
• Kev ua tsis tau haujlwm ntawm lub raum .
• Qee cov tshuaj.
• Kev phais mob, tshwj xeeb tshaj yog kev phais mob plab.
• Tshem tawm cov noob qes .
• Kev kho mob ntawm cov vitamin B12 tsis txaus.

Daim ntawv teev npe no tsuas yog suav nrog ob peb yam ua rau muaj tus kab mob Reactive Thrombocytosis xwb.

Cov tsos mob ntawm thrombocytosis yog dab tsi?

Feem ntau, cov neeg uas muaj cov ntshav platelet ntau tsis muaj tsos mob dab tsi, tsawg kawg tsis yog thaum ntxov. Yog tias koj muaj Reactive Thrombocytosis , koj yuav muaj cov tsos mob ntawm tus mob uas ua rau nws.

Txawm li cas los xij, thaum muaj cov tsos mob tshwm sim, lawv feem ntau cuam tshuam nrog kev los ntshav tsis zoo thiab cov ntshav txhaws hauv koj lub cev. Tej zaum koj yuav pom cov tsos mob zoo li:

• Mob taub hau .
• Yooj yim raug mob.
• Xav tias tsis muaj zog, kiv taub hau, lossis mob taub hau.
• Los ntshav ntawm lub qhov ntswg, qhov ncauj, thiab cov pos hniav.
• Los ntshav hauv plab los yog txoj hnyuv.

Ib txhia neeg uas muaj tus kab mob Essential Thrombocythemia (ET) yuav muaj tus mob hu ua Erythromelalgia . Qhov no ua rau mob, o, thiab liab ntawm tes thiab taw. Lawv kuj tseem yuav hnov ​​​​​​mob loog thiab tingling ntawm tes thiab taw.

Hauv cov mob hnyav, thrombocytosis tuaj yeem ua rau cov ntshav txhaws tsis zoo hauv plab (piv txwv li, Budd-Chari syndrome ) thiab ua rau muaj kev pheej hmoo ntawm kev mob stroke lossis mob plawv nres .

Yuav kuaj mob thrombocytosis li cas?

Vim tias thrombocytosis feem ntau tsis ua rau muaj tsos mob, thawj qhov cim qhia uas koj muaj yog tias kev kuaj ntshav niaj hnub (piv txwv li, Complete Blood Count - CBC ) qhia tias muaj cov platelet ntau ntxiv.

Thrombocytosis txhais tau tias muaj ntau tshaj 450,000 platelets ib microliter ntawm cov ntshav. Yog tias koj cov platelet suav siab, koj tus kws kho mob yuav xaj kom kuaj ntshav dua hauv ob peb lub lis piam kom pom tias cov ntshav tseem siab. Kev nce ib zaug ntawm cov platelet suav thiab tom qab ntawd rov qab mus rau qhov qub feem ntau tsis yog teeb meem. Txawm li cas los xij, cov ntshav siab tas li yuav qhia tau tias muaj mob nkeeg.

Yog tias muaj cov kab mob reactive thrombocytosis , kev txheeb xyuas qhov mob tseem ceeb uas ua rau muaj qhov no (piv txwv li, ntshav tsis txaus hlau , mob qog noj ntshav, kev kis kab mob) tuaj yeem pab cov kws kho mob kuaj mob thiab tswj hwm qhov no. Txawm li cas los xij, yog tias tus kws kho mob nrhiav tsis tau qhov ua rau muaj qhov no, lawv yuav ua qhov kev kuaj ntxiv kom pom tias koj puas muaj Essential Thrombocythemia (ET) .

Cov kev ntsuam xyuas no yuav suav nrog:

• Kev kuaj ntshav ntawm cov hlab ntsha sab nraud:Qhov no xyuas seb cov platelets hauv koj cov ntshav puas zoo li txawv txav.
• Kev kuaj DNA/genetic: Qhov no tuaj yeem nrhiav tau cov kev hloov pauv genetic xws li JAK2 , uas feem ntau cuam tshuam nrog ET (Essential Thrombocythemia) .
• Kev kuaj mob pob txha hauv cov pob txha: Qhov no kuaj xyuas koj cov pob txha hauv cov pob txha kom paub seb puas muaj cov hlwb tsis zoo.

Yuav kho tus kab mob thrombocytosis li cas?

Yog koj tsis muaj tsos mob, tej zaum koj tsuas yog xav tau kev kuaj mob tsis tu ncua xwb.

Feem ntau cov neeg uas muaj cov ntshav txhaws ntau dhau (xws li kev raug mob, kev kis kab mob, lossis kev tsis haum tshuaj tom qab phais) tsis tas yuav kho mob. Feem ntau, cov ntshav platelet rov qab mus rau qhov qub thaum cov mob uas ua rau muaj cov ntshav platelet ntau dhau (xws li kev raug mob, kev kis kab mob, lossis kev tsis haum tshuaj tom qab phais) ploj mus. Txawm li cas los xij, yog tias koj muaj cov tsos mob, koj tus kws kho mob yuav kho qhov ua rau muaj qhov no.

Yog tias koj muaj tus kab mob Essential Thrombocythemia (ET) thiab muaj cov tsos mob, koj tus kws kho mob yuav pom zoo ntau yam kev kho mob, xws li:

• Noj tshuaj aspirin tsawg tsawg txhua hnub: Koj tuaj yeem noj tshuaj aspirin txhua hnub kom tiv thaiv cov ntshav txhaws. Cov tshuaj tsawg tsawg no feem ntau tsis ua rau mob plab lossis los ntshav. Txawm li cas los xij, tsis txhob noj tshuaj aspirin tsis tu ncua yam tsis tau nrog koj tus kws kho mob tham.
• Noj cov tshuaj uas txo cov ntshav platelets: Cov tshuaj xws li Hydroxyurea (cov npe lag luam: Droxia®, Hydrea®, Siklos®, Mylocel®) thiab Anagrelide (lub npe lag luam: Agrilyn®) txo cov ntshav platelets hauv cov pob txha. Interferon alfa (lub npe lag luam: Multiferon®) tiv thaiv cov ntshav platelets tsis zoo los ntawm kev faib thiab sib kis.
• Muaj ib txoj kev kho mob los tshem koj cov platelets: Yog tias koj cov platelets siab heev uas koj muaj feem yuav tsim cov ntshav txhaws uas ua rau tuag taus, koj tus kws kho mob yuav pom zoo kom ua ib txoj kev kho mob hu ua plateletpheresis . Qhov no suav nrog kev siv lub tshuab los lim cov platelets ntau dhau ntawm koj cov ntshav. Txawm li cas los xij, feem ntau ntawm cov neeg mob thrombocytosis , plateletpheresis tsis tsim nyog.

Tseem Ceeb: Tsis txhob pib lossis tsum ib qho ntawm cov kev kho mob no yam tsis tau kev qhia los ntawm kws kho mob. Txhua yam yuav tsum tau tham nrog koj tus kws kho mob thiab ua raws li nws txoj kev qhia.

Puas kho tau tus kab mob thrombocytosis kom zoo?

Kev mob ntshav txhaws tseem ceeb (ET)Tam sim no tsis muaj tshuaj kho tau tus kab mob thrombocytopenia. Txawm li cas los xij, koj tus kws kho mob tuaj yeem pab koj tswj hwm tus mob kom txo koj txoj kev pheej hmoo ntawm kev ntshav txhaws. Yog tias muaj cov kab mob reactive thrombocytosis (ua los ntawm lwm yam ua rau), cov ntshav platelet feem ntau rov qab mus rau qhov qub thaum kho qhov ua rau mob.

Puas tiv thaiv tau tus kab mob thrombocytosis?

Muaj ntau yam mob uas ua rau muaj kab mob thrombocytosis uas peb tsis tuaj yeem tiv thaiv tau, suav nrog Essential Thrombocythemia (ET) .

Puas yog thrombocytosis ua rau lub neej muaj kev phom sij?

Cov ntshav platelet ntau tsis yog qhov txaus ntshai rau lub neej, tab sis cov teeb meem uas tuaj yeem tshwm sim - xws li cov ntshav txhaws lossis los ntshav hnyav - tuaj yeem ua rau muaj kev phom sij.

Feem ntau cov ua rau muaj thrombocytosis yog ib ntus xwb, thiab lawv tsis tshua ua rau cov ntshav txhaws loj heev. Hauv Essential Thrombocythemia (ET) , qhov kev pheej hmoo siab dua me ntsis. Txawm li cas los xij, koj tus kws kho mob yuav saib xyuas koj ze, sau cov tshuaj tsim nyog, thiab ua cov txheej txheem tsim nyog los tiv thaiv cov ntshav txhaws txaus ntshai. Yog li ntawd, tsis txhob txhawj.

Yuav ua li cas yog tias ib tug neeg muaj tus kab mob thrombocytosis?

Feem ntau cov kab mob ntshav txhaws uas tshwm sim los ntawm kev ua xua yuav ploj mus thaum kho qhov teeb meem tseem ceeb. Txawm hais tias koj cov ntshav platelet yuav nce siab rau lub sijhawm luv luv (thiab tej zaum yuav ntev tom qab koj lub pole raug tshem tawm), cov kab mob ntshav txhaws theem ob feem ntau tsis ua rau cov ntshav txhaws tsis zoo.

Kab mob Essential Thrombocythemia (ET) , lossis primary thrombocytosis, tuaj yeem ua rau muaj teeb meem los ntshav lossis ntshav txhaws hnyav. Kev noj tshuaj kom koj cov ntshav platelet zoo li qub tuaj yeem pab tiv thaiv qhov no. Txawm li cas los xij, tom qab ntau xyoo ntawm kev muaj tus kab mob, pob txha pob txha fibrosis (cim ntawm pob txha pob txha) tuaj yeem tshwm sim. Muaj ob peb tus neeg uas muaj Essential Thrombocythemia (ET) kuj tuaj yeem mob leukemia .

Kuv yuav tsum mus ntsib kuv tus kws kho mob thaum twg?

Ua raws li koj tus kws kho mob cov lus qhia kom meej meej txog seb koj yuav tsum mus kuaj mob ntau npaum li cas thiab seb koj puas yuav tsum tau kuaj ntshav los xyuas koj cov ntshav platelet.

Kuv yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) thaum twg?

Yog koj muaj cov tsos mob ntawm tus mob stroke lossis mob plawv nres, hu rau 1990 tam sim ntawd lossis mus rau chav kho mob ceev hauv tsev kho mob ze tshaj plaws. Yuav tsum paub txog cov tsos mob no.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Koj tuaj yeem nug koj tus kws kho mob cov lus nug xws li:

• Kuv puas yuav tsum txhawj xeeb txog kuv cov platelet siab?
• Kuv puas yuav tsum tau kuaj ntxiv kom paub tseeb tias kuv cov ntshav platelet ntau npaum li cas?
• Kuv yuav tsum tau ua dab tsi los nrhiav seb yog vim li cas kuv tus mob Thrombocytosis?
• Koj pom zoo kom muaj kev kho mob dab tsi?
• Kuv yuav ua tau dab tsi hloov kuv txoj kev ua neej kom tswj tau qhov teeb meem no?

Yog tias koj cov txiaj ntsig ntawm kev kuaj ntshav qhia tias koj cov platelets siab, tsis txhob ntshai. Koj cov platelets tuaj yeem siab rau ntau yam laj thawj. Ntau yam ntawm cov laj thawj no tsis tas yuav kho. Tab sis yog tias koj cov qib siab tas li thiab koj muaj cov tsos mob, koj tus kws kho mob yuav sim nrhiav qhov ua rau. Kev saib xyuas zoo thiab tshuaj feem ntau tuaj yeem tiv thaiv cov teeb meem loj tshaj plaws uas cuam tshuam nrog thrombocytosis.

Thaum kawg, tej yam yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Zoo, peb tau tham ntau txog Thrombocytosis hnub no, puas yog? Kuv vam tias koj nkag siab zoo txog qhov no.

Qhov tseem ceeb tshaj plaws yog tsis txhob ntshai yog tias koj pom tias koj cov ntshav platelet siab. Tsis yog txhua tus neeg mob Thrombocytosis muaj kev phom sij.

• Kab mob Reactive Thrombocytosis yog hom kab mob uas pom ntau tshaj plaws, thiab feem ntau nws yog los ntawm lwm yam ua rau ib ntus xwb. Qhov no kuj yuav zoo dua thaum kho qhov ua rau ntawd lawm.
• Kab mob Essential Thrombocythemia (ET) yog ib hom kab mob tsis tshua muaj uas yuav xav tau kev kho mob mus sij hawm ntev.
• Nco ntsoov mus kuaj mob thiab kho mob raws li koj tus kws kho mob tau hais.
• Tsis txhob tso tseg tej tsos mob. Nrhiav kev kho mob tam sim ntawd, tshwj xeeb yog tias koj los ntshav txawv txawv, mob nqaij, mob taub hau hnyav, mob hauv siab, lossis ua pa nyuaj.
• Tham nrog koj tus kws kho mob yam qhib siab lug . Nug txhua yam lus nug lossis kev txhawj xeeb uas koj muaj.

Nco ntsoov tias, koj tsis yog tib tug xwb. Yog koj muaj kev qhia thiab kev txhawb nqa los ntawm kws kho mob zoo, koj yuav tswj tau qhov teeb meem no tau zoo thiab ua neej noj qab nyob zoo.