Puas yog koj lub cev tiv thaiv kab mob ua rau koj vwm? Cia peb kawm txog tus kab mob Autoimmune Pancreatitis yooj yim!

Peb muaj ib lub cev tiv thaiv kab mob zoo kawg nkaus hauv peb lub cev, puas yog? Qhov ntawd yog qhov peb hu ua lub cev tiv thaiv kab mob. Nws tiv thaiv peb los ntawm kev tawm tsam cov kab mob, cov kab mob me me, thiab cov kab mob uas ua rau muaj kab mob. Tab sis xav txog, yuav ua li cas yog tias qee zaum lub cev tiv thaiv kab mob no ntawm peb tus kheej tsis meej pem nrog cov hlwb zoo hauv peb lub cev thiab pib tawm tsam lawv? Thaum ntawd nws tshwm sim, hu ua "Autoimmune Pancreatitis". Hais yooj yim, koj tus kheej lub cev tiv thaiv kab mob pib ua haujlwm tawm tsam koj lub pancreas.

"Autoimmune Pancreatitis" yog dab tsi? Hais yooj yim xwb...

Xav txog koj lub cev tiv thaiv kab mob zoo li ib pab tub rog uas tiv thaiv lub teb chaws. Txoj hauj lwm ntawm pab tub rog no yog los tiv thaiv lub teb chaws ntawm cov yeeb ncuab sab nraud (xws li cov kab mob thiab cov kab mob virus). Tab sis hauv '(Autoimmune Pancreatitis)', pab tub rog no ua yuam kev thiab tawm tsam cov pej xeem tsis muaj txim ntawm nws lub teb chaws (uas yog, cov hlwb noj qab haus huv hauv lub pancreas) xav tias lawv yog cov yeeb ncuab. Yog li ntawd, lub pancreas yuav o, raug mob, thiab nws txoj haujlwm tsis zoo. Qhov no yog qhov peb hu ua autoimmune pancreatitis .

Kab mob no feem ntau tshwm sim li cas?

Tseeb tiag, '(Autoimmune Pancreatitis)' yog ib yam kab mob tsis tshua muaj . Feem ntau nws tshwm sim rau li ib tug ntawm ib puas txhiab tus neeg. Yog tias peb coj cov mob o ntawm lub pancreas mus sij hawm ntev ('chronic pancreatitis'), tsuas yog li ntawm 2% ntawm lawv poob rau hauv pawg '(Autoimmune Pancreatitis)' no. Yog li, qhov no tsis yog ib yam kab mob uas cuam tshuam rau txhua tus.

Puas muaj hom kab mob '(Autoimmune Pancreatitis)'?

Yog, muaj ob hom kab mob hu ua "(Autoimmune Pancreatitis). Cia peb saib seb lawv yog dab tsi.

1. Kab mob Pancreatitis hom 1 uas tiv thaiv kab mob los ntawm tus kheej

Qhov no yog hom uas feem ntau pom . Hauv qhov no, peb muaj ntau cov protein hu ua `(Immunoglobulin G4)` lossis `(IgG4)` hauv peb lub cev. Qhov `(IgG4)` no yog ib hom tshuaj tiv thaiv kab mob. Thaum muaj o lossis o nyob qhov twg hauv lub cev, qib ntawm `(IgG4)` no nce ntxiv.

Tiam sis hom mob thawj no, qhov teeb meem tsis yog tsuas yog nrog lub txiav xwb. Nws kuj tseem tuaj yeem cuam tshuam rau lwm yam kab mob hauv peb lub cev. Piv txwv li:

• Cov kav dej kua tsib: Cov no yog cov raj zoo li lub raj uas nqa cov kua tsib los ntawm lub siab mus rau txoj hnyuv me.
• Cov hlab ntsha hauv lub cev: Cov hlab ntsha hauv lub cev.
• Siab
• Lub ntsws
• Lub zais zis
• Cov qog salivary
• Cov qog thyroid

Kuj tseem tuaj yeem o thiab puas tsuaj rau cov chaw zoo li no.

2. Kab mob Pancreatitis hom 2 uas tiv thaiv kab mob los ntawm tus kheej

Hom no tsuas yog cuam tshuam rau lub txiav pancreas xwb . Qhov tshwm sim ntawm no yog tias ib hom qe ntshav dawb hu ua "neutrophils" ua rau lub txiav pancreas thiab cov hlab ntsha pancreas puas tsuaj. Qhov mob no feem ntau pom muaj rau cov neeg hluas.Lawv kuj tseem muaj feem yuav muaj tus kab mob plab hnyuv (IBD) ntau dua.

Dab tsi yog cov ua rau muaj '(Autoimmune Pancreatitis)'? Puas muaj tej yam uas ua rau muaj kev pheej hmoo?

Cov kws tshawb nrhiav tseem tab tom sim nrhiav seb yog vim li cas tiag , tab sis feem ntau nws tshwm sim rau cov neeg hnub nyoog ntawm 50 thiab 60 xyoo. Txawm li cas los xij, nws tuaj yeem tshwm sim ua ntej. Cov txiv neej muaj feem yuav mob tus kab mob ob npaug ntau dua li cov poj niam.

Qee zaum, nws yog ib qho kev ua xua ntawm lub cev tiv thaiv kab mob rau cov kab mob bacterial. Tsis tas li ntawd, cov neeg uas muaj lwm yam kab mob autoimmune muaj feem yuav mob nws ntau dua. Piv txwv li:

• (Hashimoto's thyroiditis): Qhov no ua rau cov thyroid ua haujlwm tsawg dua (hypothyroidism).
• (Kab mob plab hnyuv - IBD): Tshwj xeeb tshaj yog cov mob xws li '(ulcerative colitis)'.
• (Kab mob biliary cholangitis thawj zaug)
• Retroperitoneal fibrosis: Kev tsim cov nqaij zoo li caws pliav hauv daim ntaub ntawm sab nraub qaum ntawm lub plab.
• Mob pob qij txha caj qaum: o ntawm cov pob qij txha.
• (Sarcoidosis)
• (Sjögren's syndrome)

Yog tias koj muaj lwm yam mob autoimmune zoo li no, nws yog ib lub tswv yim zoo kom txhawj xeeb me ntsis txog Autoimmune Pancreatitis thiab.

Cov tsos mob ntawm '(Autoimmune Pancreatitis)' yog dab tsi?

Thaum pib mob no , tej zaum yuav tsis muaj tsos mob dab tsi li . Txawm li cas los xij, thaum tus mob loj zuj zus tuaj, cov hlab ntsha hauv lub plab pib nqaim, ua rau cov enzymes uas lub plab tso tawm tsis tuaj yeem hla mus tau zoo.

Kev txhaws hauv cov hlab ntsha pancreatic yuav ua rau muaj cov tsos mob xws li:

• Mob plab sab saud
• Mob nraub qaum nruab nrab
• Mob raws plab
• Xeev siab/ntuav
• Kev poob phaus

Tseem Ceeb: Qee cov tsos mob no kuj tuaj yeem pom hauv mob qog noj ntshav pancreatic. Yog li ntawd, yog tias koj muaj cov tsos mob no, nws yog qhov zoo kom tsis txhob ntshai thiab mus ntsib kws kho mob tam sim ntawd kom paub meej tias qhov teeb meem yog dab tsi . Muaj '(Autoimmune Pancreatitis)' tsis tau txhais hais tias koj muaj mob qog noj ntshav.

Ntxiv mus, tus kab mob autoimmune pancreatitis tuaj yeem ua rau o, cov qog tsis yog mob qog noj ntshav, thiab cov kua dej hauv lub pancreas. Yog tias cov o, cov pob, lossis cov cysts no tshwm sim hauv lub taub hau ntawm koj lub pancreas, lawv tuaj yeem thaiv cov kav dej ntawm cov kua tsib, uas tuaj yeem tiv thaiv cov kua tsib kom tsis txhob ntws mus rau hauv txoj hnyuv me. Cov kua tsib muaj cov xim hu ua bilirubin. Thaum cov bilirubin no sib sau ua ke hauv cov ntshav, nws tuaj yeem ua rau mob daj ntseg.Daim tawv nqaij thiab lub qhov muag dawb yuav daj (jaundice), thiab koj yuav xav tias nkees. Thaum bilirubin nce ntxiv hauv cov zis , cov zis yuav tsaus . Thaum bilirubin raug tso tawm hauv cov hnyuv , cov quav yuav daj ntseg .

Cov teeb meem uas yuav tshwm sim ntawm '(Autoimmune Pancreatitis)' yog dab tsi?

Kev mob pancreas mus ntev tuaj yeem ua rau xeev siab, poob phaus, thiab mob tas li hauv plab thiab nraub qaum. Tsis tas li ntawd, yog tias cov hlwb tsim insulin hauv pancreas raug puas tsuaj , ntshav qab zib tuaj yeem tshwm sim.

Cov tshuaj tiv thaiv IgG4 tsis yog tuaj yeem tawm tsam tsis yog lub txiav xwb, tab sis kuj tseem tawm tsam lwm yam kabmob, tshwj xeeb tshaj yog Hom 1. Cov kabmob no suav nrog:

• Cov kav dej ntawm cov kua tsib
• Cov qog salivary
• Cov qog kua muag
• Lub qog thyroid ('Thyroid')
• Cov raum
• Lub plawv
• Lub ntsws thiab pleura (txheej ntawm lub ntsws)

Yuav kuaj mob Autoimmune Pancreatitis li cas?

Yuav kom paub tseeb tias tus kab mob no tsis yog mob qog nqaij hlav pancreatic, yuav tsum tau kuaj ntau zaus. Koj yuav tsum tau kuaj xws li cov no:

• Kev kuaj ntshav: Cov no kuaj seb puas muaj IgG4 ntau dhau, nrog rau kev ua haujlwm ntawm daim siab thiab cov qib ntawm qee hom qe ntshav.
• Kev kuaj duab: Cov no xyuas seb qhov loj ntawm lub qog pancreas puas muaj qhov caws pliav, lossis seb cov hlab ntsha puas nqaim. Piv txwv ntawm cov kev kuaj no yog `(CT scan)` thiab `(MRI scan)`.
• Kev Siv Biopsy: Qhov no suav nrog kev rho ib daim nqaij me me ntawm koj lub pancreas thiab kuaj nws hauv qab lub tshuab microscope. Qhov no feem ntau ua tiav los ntawm kev phais endoscopic minimally invasive hu ua Endoscopic Ultrasound (EUS). Hauv cov txheej txheem no, koj tus kws kho mob ntxig ib lub raj ntev, yoog tau (nrog lub teeb thiab lub cuab yeej ultrasound ntawm ib kawg) rau hauv koj lub plab thiab cov hnyuv kom saib koj lub pancreas. Tom qab ntawd ib qho qauv biopsy raug coj los ntawm koj lub plab lossis cov hnyuv. Qee zaum, tus kws phais yuav tsum tau ua ib qho me me ntawm koj daim tawv nqaij (laparoscopy) kom tau txais cov qauv biopsy.
• Kev sim tshuaj Corticosteroid: Qhov no kuj pab kom paub tseeb tias koj tau kuaj mob lawm. Koj yuav tau noj tshuaj steroids rau lub sijhawm luv luv kom pom tias koj cov qib IgG4 puas txo qis thiab koj cov kev kuaj duab puas zoo dua.

Yuav kho tus kab mob "Autoimmune Pancreatitis" li cas?

Qhov xav tsis thoob yog, rau ib co neeg tsawg heev, tus kab mob no ploj mus ntawm nws tus kheej yam tsis tas yuav kho dab tsi li . Tab sis rau ntau tus, kev kho mob yog qhov yuav tsum tau ua .

Kab mob Pancreatitis autoimmune feem ntau yog kho nrog corticosteroids.Ib hom tshuaj hu ua steroid. Piv txwv li, ib yam tshuaj zoo li '(prednisone)' lossis '(prednisolone)'. Cov tshuaj no ua haujlwm los ntawm kev txo qhov o thiab ua kom lub cev tiv thaiv kab mob tsis ua haujlwm zoo. Kev kho mob feem ntau pib nrog kev noj tshuaj steroid ntau. Tom qab ntawd maj mam txo qhov koob tshuaj ('tapered').

Yog tias koj tsis muaj teeb meem, feem ntau koj tsis tas yuav kho mob ntxiv. Kev kho mob uas xav tau nyob ntawm seb hom teeb meem ntawd yog dab tsi. Yog tias muaj kev nqaim ntawm cov hlab ntsha pancreatic ('duct narrowing'), ib qho txheej txheem yuav raug ua los qhib cov hlab ntsha thiab txhawb nws nrog lub cuab yeej hollow mesh ('stent').

Kuv puas tuaj yeem tiv thaiv kom tsis txhob muaj '(Autoimmune Pancreatitis)'?

Qhov tseeb, tsis muaj dab tsi koj ua tau los tiv thaiv tus kab mob no kom tsis txhob loj hlob vim nws yog teeb meem nrog peb lub cev tiv thaiv kab mob.

Yuav ua li cas rau cov neeg uas muaj '(Autoimmune Pancreatitis)'?

Feem ntau cov neeg zoo rov qab zoo tom qab kev kho mob corticosteroid , thiab tsis muaj teeb meem dab tsi. Kev muaj tus kab mob autoimmune pancreatitis tsis cuam tshuam rau koj lub neej ntev .

Txawm li cas los xij, '(Autoimmune Pancreatitis)' tuaj yeem rov qab los (rov qab los) . Qhov no feem ntau tshwm sim rau cov neeg uas muaj hom thawj ('Hom 1'). Tus kab mob no feem ntau yuav rov qab los hauv peb xyoos tom qab kuaj pom. Tus neeg uas muaj tus kab mob no kuj yuav rov qab los dua.

Yog tias tus kab mob rov qab los dua, yuav ua li cas?

Yog tias tswj tau zoo, txawm tias cov neeg uas muaj kab mob rov tshwm sim tuaj yeem ua neej nquag thiab noj qab nyob zoo .

Tej zaum koj yuav tau pib siv cov tshuaj corticosteroids dua. Ib txhia neeg txuas ntxiv kho cov tshuaj steroid rau ntau xyoo kom tiv thaiv cov tsos mob kom tsis txhob rov qab los. Cov kws kho mob kuj tseem yuav sim lwm cov tshuaj uas kho cov kab mob tiv thaiv kab mob uas ua haujlwm ntau dhau (cov tshuaj immunomodulating thiab cov tshuaj immunosuppressive).

Kuv yuav xav li cas thaum lub sijhawm kho mob?

Tej zaum yuav muaj tej yam tshwm sim tsis zoo thaum siv cov tshuaj steroids. Piv txwv li, mob plab, noj mov ntau ntxiv, tsis so, thiab pw tsaug zog tsis taus. Tej yam tshwm sim tsis zoo no yuav ua rau lub neej niaj hnub tsis zoo me ntsis, tab sis tsuas yog ib ntus xwb . Yuav kom tau txiaj ntsig ntau tshaj plaws ntawm koj txoj kev kho mob Autoimmune Pancreatitis, nws yog ib qho tseem ceeb uas yuav tsum noj cov tshuaj steroids raws li koj tus kws kho mob tau hais .

Yog tias cov kev mob tshwm sim tsis zoo ua rau koj tsis xis nyob, nco ntsoov qhia rau koj tus kws kho mob ua ntej koj tsum tsis txhob noj tshuaj. Nws yuav sau ntawv kom koj noj tshuaj ntxiv kom pab koj zoo dua, lossis hloov koj txoj kev npaj kho mob.

Thaum twg kuv thiaj rov qab mus ua ub ua no li qub tom qab kho mob rau '(Autoimmune Pancreatitis)'?

Kev kho mob Steroid feem ntau muab kev pab txo cov tsos mob ntawm '(Autoimmune Pancreatitis)' hauv ob peb lub lis piam.Muaj coob tus neeg rov qab mus ua lawv tej dej num li qub tom qab lawv cov tsos mob ploj mus lawm.

Kab mob Autoimmune Pancreatitis yog ib yam mob uas tsis tshua muaj uas ua rau lub cev tsis ua haujlwm zoo. Kev mus ntsib kws kho mob uas paub txog cov kab mob pancreatic tuaj yeem pab koj tau txais kev kho mob zoo tshaj plaws uas koj xav tau. Cov neeg feem coob rov zoo tag nrho tom qab noj tshuaj steroids . Ib txhia neeg yuav xav tau kev kho mob Autoimmune Pancreatitis ntxiv kom ua tiav kev pab mus sij hawm ntev.

Thaum kawg, nco ntsoov qhov no (Cov Lus Coj Mus Tsev)

• Kab mob Autoimmune Pancreatitis yog ib qho mob tsis tshua muaj uas koj lub cev tiv thaiv kab mob tawm tsam koj lub txiav.
• Yog koj muaj cov tsos mob xws li mob plab, poob phaus, lossis mob daj ntseg , nco ntsoov nrhiav kev pab kho mob .
• Qhov no tsis yog mob qog nqaij hlav pancreatic, tab sis cov tsos mob zoo sib xws, yog li kev kuaj mob kom raug yog qhov tseem ceeb .
• Kev kho mob tseem ceeb yog corticosteroids.
• Muaj ntau tus neeg zoo rov qab zoo los ntawm kev kho mob, tab sis tus kab mob no tuaj yeem rov qab los dua.
• Nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li tus kws kho mob cov lus qhia kom meej meej kom rov zoo sai .

Nco ntsoov tias, koj tsis yog tib tug xwb. Nws yog ib qho ib txwm muaj ntau yam kev xav khiav hauv koj lub siab hauv qhov xwm txheej zoo li no. Yog li, qhib siab nrog koj tus kws kho mob thiab nug koj cov lus nug. Lawv nyob ntawm no los pab koj.

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