Koj puas muaj cov tsos mob txawv txawv no? Cia peb tham txog Carcinoid Syndrome!

Qee zaum peb tsis paub meej tias muaj dab tsi tshwm sim hauv peb lub cev, puas yog? Koj puas tau muaj kev kub ntxhov tam sim ntawd, ua pa nyuaj, mob plab, thiab raws plab? Cov no tsis yog tej yam uas tsis tau xav txog. Qee zaum cov no yuav yog cov tsos mob ntawm tus mob tsis tshua muaj hu ua Carcinoid Syndrome. Cia peb tham txog qhov no kom ntxaws ntxiv hnub no.

Carcinoid Syndrome yog dab tsi?

Hais yooj yim xwb, carcinoid syndrome yog ib pawg ntawm cov tsos mob uas tshwm sim los ntawm ib hom qog nqaij hlav loj hlob hauv koj lub cev hu ua neuroendocrine tumors (NETs) . Cov hlwb neuroendocrine no yog ib hom hlwb tshwj xeeb uas koom nrog peb cov hlab ntsha thiab cov tshuaj hormones. NETs tshwm sim thaum cov hlwb no tam sim ntawd faib thiab loj hlob sai, tsim cov qog nqaij hlav.

Tam sim no tej zaum koj yuav xav paub seb qhov no puas yog ib yam kab mob uas cuam tshuam rau txhua tus. Tsis yog, nws yog ib qho mob tsis tshua muaj . Kev tshawb fawb qhia tau tias kwv yees li ib ntawm tsib tus neeg uas muaj cov qog neuroendocrine (NETs) muaj mob carcinoid syndrome. NETs kuj tsis tshua muaj, nrog rau kwv yees li ntawm 5 ntawm 100,000 hauv Tebchaws Meskas.

Cov NETs no, tshwj xeeb tshaj yog cov nyob hauv koj txoj hnyuv lossis lub ntsws, tso tawm ntau cov tshuaj hormones xws li serotonin thiab lwm yam tshuaj lom neeg rau hauv lub cev ib zaug. Thaum ntawd cov tsos mob ntawm carcinoid syndrome tshwm sim. Qee zaum, koj thawj zaug paub tias koj muaj NET tom qab cov tsos mob ntawm tus kab mob no tshwm sim.

Tsis tshua muaj, yog tias tus kab mob carcinoid no tsis raug kuaj pom thiab kho kom zoo, nws tuaj yeem ua rau muaj xwm txheej ceev uas txaus ntshai rau lub neej hu ua 'carcinoid crisis.' Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum paub txog qhov no.

Cov tsos mob ntawm Carcinoid Syndrome yog dab tsi?

Cia peb saib cov tsos mob feem ntau ntawm tus mob no. Saib seb koj puas muaj cov tsos mob no, ib qho zuj zus:

• Ntshai: Qhov no yuav ua rau koj tsis xis nyob me ntsis. Zoo li koj ntsej muag liab thaum koj txaj muag, tab sis yog tias nws tshwm sim ntau zaus yam tsis muaj laj thawj, koj yuav tsum txhawj xeeb.
• Ua pa nrov nrov thiab ua tsis taus pa (dyspnea): Tej zaum yuav zoo li ua pa nyuaj, lossis zoo li lub suab hu nkauj los ntawm hauv siab.
• Mob plab thiab raws plab heev thiab nquag: Mob plab nrog rau raws plab hnyav tas li. Qee zaum nws nyuaj rau tswj.
• Cov roj ntsha uas muaj ntxhiab tsw phem: Cov quav yuav zoo li roj thiab muaj ntxhiab tsw txawv txawv.
• Koj txhais taw thiab ob txhais ceg o los yog o:Qhov no qee zaum tuaj yeem yog ib qho tsos mob ntawm lub plawv tsis ua haujlwm, yog li nws yog ib qho tseem ceeb uas yuav tsum nrhiav kev pab kho mob sai sai.
• Txo kev ntshaw kev sib deev lossis kev ua haujlwm tsis zoo ntawm erectile hauv cov txiv neej: Qee tus neeg yuav muaj cov mob no.
• Tawv nqaij thiab qhov muag dawb daj (Jaundice): Qhov no yog qhov peb hu ua 'jaundice'. Nws yuav yog teeb meem siab.
• Kiv taub hau los yog xav tias tsaus muag: Qhov no tuaj yeem yog ib qho cim qhia tias ntshav siab qis.
• Xav tias koj lub plawv dhia ceev: Tej zaum koj yuav xav tias koj lub hauv siab dhia ceev dua.

Yog tias koj tseem muaj ib lossis ntau yam ntawm cov tsos mob no, nco ntsoov mus ntsib kws kho mob kom tham txog lawv. Cov no kuj tuaj yeem yog cov tsos mob ntawm lwm yam mob, tab sis nws yog ib qho tseem ceeb kom paub tseeb tias koj muaj carcinoid syndrome.

Vim li cas tus mob carcinoid syndrome no thiaj tshwm sim?

Zoo li kuv tau hais ua ntej lawm, mob carcinoid syndrome tshwm sim yog tias koj muaj cov qog neuroendocrine (NETs). Cov NETs no yog cov qog uas tsim los ntawm cov hlwb tshwj xeeb hauv koj lub cev neuroendocrine. Cov hlwb no tsim thiab tso cov tshuaj hormones rau hauv lub cev.

Feem ntau, cov NETs no tuaj yeem tshwm sim rau hauv cov chaw xws li koj txoj hnyuv plab, ntsws, thiab pancreas. Txawm li cas los xij, carcinoid syndrome feem ntau yog tshwm sim los ntawm NETs hauv txoj hnyuv plab lossis ntsws tso tawm ntau cov tshuaj hormones (tshwj xeeb tshaj yog serotonin) rau hauv cov ntshav.

Xav txog nws zoo li lub qhov dej uas maj mam tig rau ntawm cov dej, cov hlwb no feem ntau tso cov tshuaj hormones me me. Tab sis thaum lub NET tsim, nws zoo li lub qhov dej qhib dav dav, thiab ntau cov tshuaj hormones tawm los ib zaug. Thaum ntawd cov tsos mob ntawm tus kab mob no tshwm sim.

Leej twg muaj feem yuav mob carcinoid syndrome ntau dua?

Qhov ua rau muaj kev pheej hmoo tseem ceeb yog muaj qog neuroendocrine (NET) hauv koj txoj hnyuv lossis lub ntsws . Hauv lwm lo lus, carcinoid syndrome feem ntau tsis tshwm sim yog tsis muaj NET.

Qhov ntawd txhais tau tias, yog tias koj tau kuaj pom tias muaj NETs, ​​koj kuj yuav tsum txhawj xeeb txog tus kab mob no. Qee zaum, yog tias ib tug neeg hauv tsev neeg tau muaj NETs, ​​qhov ntawd kuj tuaj yeem ua rau muaj kev pheej hmoo rau qee qhov, tab sis nws tsis tshua muaj.

Cov teeb meem uas yuav muaj tau ntawm Carcinoid Syndrome yog dab tsi?

Kab mob Carcinoid syndrome tsis yog tsuas yog ib pawg ntawm cov tsos mob xwb, nws tuaj yeem ua rau muaj ntau yam teeb meem loj heev. Ib qho mob zoo li no yog qhov mob uas yuav ua rau tuag taus hu ua 'carcinoid crisis' uas kuv tau hais ua ntej.

Cia peb saib ob peb yam teeb meem ntxiv:

• Kab mob plawv carcinoid:Qhov no kuj tsis tshua muaj, tab sis tuaj yeem ua rau tuag taus. Cov tshuaj hormones uas NETs tso tawm cuam tshuam rau cov txheej ntawm koj lub plawv, cov qhov (valves), thiab cov hlab ntsha. Qhov no tuaj yeem ua rau lub plawv tsis ua haujlwm.
• Mesenteric fibrosis: NETs tuaj yeem ua rau o thiab ua rau mob ntawm mesentery, cov ntaub so ntswg uas txuas koj cov hnyuv rau koj phab ntsa plab. Qhov no tuaj yeem cuam tshuam rau kev ua haujlwm ntawm cov hnyuv.
• Kev Nyuaj Siab: Carcinoid syndrome tuaj yeem cuam tshuam rau koj lub cev lub peev xwm siv cov amino acid tseem ceeb hu ua tryptophan. Tryptophan pab tsim serotonin. Serotonin yog ib yam tshuaj lom neeg hauv lub hlwb uas tswj cov yam xws li peb lub siab, tus cwj pwm, thiab kev pw tsaug zog. Yog li cov serotonin qis tuaj yeem ua rau muaj kev nyuaj siab.

Qhov mob txaus ntshai hu ua carcinoid crisis

Kev kub ntxhov ntawm cov qog nqaij hlav yog ib qho xwm txheej ceev uas tsis tshua muaj tab sis muaj peev xwm ua rau tuag taus . Nws tuaj yeem tshwm sim los ntawm kev phais, lwm yam kev kho mob, lossis kev raug mob los ntawm kev sib tsoo.

Cov yam ntxwv ntawm qhov no yog:

• Kev hloov pauv loj ntawm cov ntshav siab: Cov ntshav siab tuaj yeem poob qis dhau (hypotension) lossis nce siab dhau.
• Ntshav liab heev: Tag nrho lub cev hloov liab tam sim ntawd thiab tej zaum yuav kub.
• Ua pa nyuaj (Dyspnea): Tej zaum yuav ua pa luv luv heev.
• Kev tsis meej pem: Tej zaum koj yuav xav tias koj lub siab raug cuam tshuam.

Nws yog ib qho tseem ceeb heev rau ib tus neeg uas muaj tus kab mob carcinoid syndrome lossis tus kab mob neuroendocrine (NET) kom nqa daim npav qhia txog lawv tus mob. Qhov no tuaj yeem pab tau zoo heev yog tias lawv xav tau kev kho mob thaum muaj xwm txheej ceev. Tsis tas li ntawd, yog tias koj yuav phais, nws yog ib qho tseem ceeb uas yuav tsum qhia rau koj cov kws kho mob txog tus mob no. Tom qab ntawd lawv tuaj yeem muab tshuaj rau koj ua ntej thiab thaum lub sijhawm phais kom txo qhov kev pheej hmoo ntawm 'carcinoid crisis'.

Yuav kuaj mob Carcinoid Syndrome li cas?

Cov kws kho mob siv ntau yam kev kuaj mob los kuaj mob no. Cia peb saib seb lawv yog dab tsi:

• Kev kuaj zis: Qhov no kuaj xyuas cov qib ntawm qee cov tshuaj hormones hauv koj cov zis, tshwj xeeb yog cov khoom lag luam ntawm serotonin hu ua 5-HIAA (5-hydroxyindoleacetic acid) .
• Kev kuaj mob thiab keeb kwm kho mob: Cov tsos mob ntawm carcinoid syndrome zoo ib yam li lwm yam kab mob uas tsis hnyav heev, yog li koj tus kws kho mob yuav nug koj kom meej txog koj cov tsos mob, lawv tau tshwm sim ntev npaum li cas, thiab seb lawv puas zuj zus tuaj.
• Kev kuaj ntshav:Cov no kuaj xyuas cov theem ntawm cov tshuaj uas tso tawm rau hauv cov ntshav los ntawm koj cov kab mob thiab cov nqaij. Yog tias cov theem ntawm qee yam tshuaj nce lossis poob sai sai, nws tuaj yeem yog ib qho cim ntawm kab mob. Piv txwv li, lawv saib ib qho cim hu ua Chromogranin A.
• Kev ntsuas Neuroendocrine Positron Emission Tomography (PET): Qhov no yog kev ntsuas tshwj xeeb uas siv cov xim hu ua gallium 68 dotatate los nrhiav qhov chaw ntawm cov qog neuroendocrine (NETs).
• Kev thaij duab CT: Kev thaij duab CT siv cov duab X-ray thiab lub khoos phis tawj los tsim cov duab peb-seem (3D) ntawm koj cov kabmob thiab pob txha. Qhov no kuj tseem tuaj yeem pab txiav txim siab qhov chaw thiab qhov loj ntawm cov qog.
• Kev ntsuas ultrasound: Qhov no siv cov suab nthwv dej los tsim cov duab ntawm cov kabmob.
• Kev thaij duab MRI (Magnetic Resonance Imaging (MRI): Qhov no siv lub hlau nplaum loj, cov nthwv dej xov tooj cua, thiab lub khoos phis tawj los tsim cov duab ntxaws ntxaws ntawm sab hauv lub cev.
• Kev kuaj mob hauv plab (endoscopy): Hauv qhov kev kuaj no, tus kws kho mob yuav muab ib lub raj ntev, nyias nyias uas muaj lub koob yees duab thiab lub teeb ntxig rau hauv koj lub cev kom kuaj xyuas nws. Piv txwv li, cov txheej txheem no siv tau los kuaj xyuas lub plab lossis cov hnyuv.

Cov kev kho mob rau Carcinoid Syndrome yog dab tsi?

Kab mob Carcinoid yog tshwm sim los ntawm cov qog nqaij hlav neuroendocrine (NETs). Yog li, thaum cov qog nqaij hlav ntawd raug kho, cov kab mob no kuj raug kho.

Muaj ntau txoj kev kho mob tseem ceeb:

• Kev Phais Mob: Cov qog nqaij hlav neuroendocrine tuaj yeem raug tshem tawm tag nrho lossis txo qhov loj me. Hom kev phais mob nyob ntawm qhov chaw thiab qhov loj ntawm cov qog nqaij hlav.
• Cov tshuaj Somatostatin analogs: Cov no yog ib hom tshuaj tshwj xeeb. Cov tshuaj no tuaj yeem tiv thaiv koj lub cev kom tsis txhob tsim cov tshuaj hormones ntau dhau. Lawv kuj tseem tuaj yeem pab tswj kev loj hlob ntawm cov qog thaum cov qog nqaij hlav tau kis mus rau lwm qhov ntawm lub cev (metastasis). Piv txwv li suav nrog cov tshuaj hu ua Octreotide thiab Lanreotide .
• Kev kho mob tsom rau cov hom phiaj: Qhov no kuj yog ib txoj kev kho mob tshwj xeeb uas siv los tua cov hlwb qog noj ntshav. Hauv qhov no, cov tshuaj raug muab rau cov hom phiaj tshwj xeeb lossis cov protein hauv cov hlwb qog noj ntshav.
• Kev kho mob qog noj ntshav: Qhov no siv cov tshuaj los tua cov hlwb qog noj ntshav. Kev kho mob qog noj ntshav tsis ua haujlwm zoo ib yam rau txhua hom NETs.
• Kev Siv Tshuaj Txhaj: Hauv txoj kev no, cov hlab ntsha uas xa cov ntshav mus rau qhov mob qog raug thaiv, ua rau qhov mob qog puas tsuaj. Qhov no yog kev kho mob uas siv tshwj xeeb rau NETs hauv lub siab.

Puas tiv thaiv tau tus kab mob Carcinoid Syndrome?

Tiag tiag,Tsis muaj ib txoj kev twg los tiv thaiv tau tus kab mob carcinoid syndrome vim nws cuam tshuam nrog cov qog nqaij hlav neuroendocrine (NETs). Vim tias tsis muaj txoj kev paub los tiv thaiv kev loj hlob ntawm NETs, ​​​​tsis muaj txoj hauv kev los tiv thaiv cov tsos mob uas tshwm sim los ntawm lawv.

Txawm li cas los xij, yog tias koj paub tias koj muaj NET, kev paub txog cov tsos mob ntawm carcinoid syndrome thaum ntxov thiab pib kho mob tuaj yeem txo qhov kev pheej hmoo ntawm cov teeb meem.

Kuv yuav saib xyuas kuv tus kheej li cas? / Kuv yuav tswj cov tsos mob li cas?

Yog tias koj muaj mob carcinoid syndrome, koj kuj tseem yuav muaj qog neuroendocrine (NET). Yog li, yog tias koj muaj cov tsos mob ntawm carcinoid syndrome, qhia rau koj tus kws kho mob tam sim ntawd. Lawv tuaj yeem soj ntsuam koj tus mob thiab pom zoo rau kev kuaj mob tsim nyog los saib seb koj puas muaj NET.

Peb yam tsos mob tseem ceeb ntawm tus kab mob carcinoid syndrome yog ntsej muag liab, ua pa nrov nrov, thiab raws plab. Nov yog ob peb yam uas koj ua tau los pab tswj cov no:

• Kev ntxuav ntsej muag: Qhov no yog koj lub paj hlwb teb rau kev ntxhov siab ntawm lub cev lossis lub hlwb. Yuav kom txo qhov no, ua pa tob tob, so koj lub ntsej muag thiab hauv siab nrog daim ntaub ntub dej, lossis mus rau qhov chaw huab cua ntshiab sab nraum zoov. Tsis txhob haus cawv kuj tseem yuav pab tau.
• Ua pa nrov nrov: Yog tias ua tsis taus pa, sim haus tshuaj yej lossis siv lub tshuaj nqus pa lossis lub tshuab ua pa . Yog tias koj haus luam yeeb, sim tso tseg. Kev haus luam yeeb tuaj yeem ua rau koj txoj hlab pa o ntxiv.
• Raws plab: Yog tias raws plab yog teeb meem rau koj, nrog koj tus kws kho mob tham txog cov hau kev los txo qhov zaus thiab qhov hnyav. Muaj cov tshuaj tshwj xeeb uas tsim los tswj kev raws plab uas tshwm sim los ntawm carcinoid syndrome. Tsis tas li ntawd, cov khoom noj uas muaj roj ntau, ntsim, thiab cov khoom noj mis nyuj tuaj yeem ua rau qhov mob no hnyav dua rau qee tus neeg. Yog li ntawd, ceev faj txog yam koj noj.

Thaum twg kuv yuav tsum mus ntsib kws kho mob? / Thaum twg kuv yuav tsum mus rau chav kho mob ceev?

Yog tias koj cov tsos mob ntawm tus kab mob carcinoid syndrome zuj zus tuaj, nco ntsoov mus ntsib kws kho mob. Yog tias koj tab tom kho mob NET, qhia rau koj tus kws kho mob yog tias koj pom muaj kev hloov pauv tshiab hauv koj lub cev uas yuav zoo li cov tsos mob NET. Cov kev hloov pauv no yuav tsis muaj feem cuam tshuam nrog koj qhov kev kuaj mob NET, tab sis txoj hauv kev zoo tshaj plaws kom paub tseeb yog tham nrog koj tus kws kho mob. Tsis tas li ntawd, yog tias koj cov tsos mob lossis cov kev mob tshwm sim los ntawm koj txoj kev kho mob zuj zus tuaj, qhia rau koj tus kws kho mob.

Thaum twg yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU)

Yog tias tsis kho tus mob carcinoid syndrome, cov tsos mob yuav hnyav zuj zus tuaj thiab ua rau muaj kev phom sij rau lub neej hu ua 'carcinoid crisis.' Yog li ntawd, mus rau chav kho mob ceev hauv tsev kho mob tam sim ntawd yog tias koj muaj:

• Yog tias koj lub plawv dhia tsis xwm yeem lossis mob hauv siab.
• Yog koj raws plab hnyav heev tau ob peb hnub.
• Yog koj mob plab heev.
• Yog koj xav tias koj tsis muaj zog.
• Yog koj lub ntsej muag, caj dab, thiab hauv siab liab sai sai thiab hnyav heev (mob liab sai sai).

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Kab mob Carcinoid syndrome yog ib qho cim qhia tias koj muaj qog nqaij hlav neuroendocrine (NET). Yog li ntawd, yog tias koj muaj lus nug txog kab mob carcinoid syndrome, koj yuav muaj ntau cov lus nug txog NETs. Nov yog qee cov lus nug uas koj tuaj yeem nug koj tus kws kho mob:

• Yog tias kuv muaj tus mob carcinoid syndrome, kuv yuav paub li cas yog tias kuv muaj qog neuroendocrine?
• Yog tias kuv muaj ib lub qog, nws nyob qhov twg hauv kuv lub cev?
• Cov kev kho mob rau kuv tus mob qog nqaij hlav yog dab tsi?
• Cov kev mob tshwm sim ntawm kev kho mob yog dab tsi?
• Puas kho tau tus mob qog nqaij hlav neuroendocrine uas ua rau kuv tus mob carcinoid syndrome kom zoo tag nrho?
• Puas yog tus mob carcinoid syndrome rov qab los tom qab kuv tus mob neuroendocrine tau kho lawm?

Cov Lus Xaus Kawg coj mus tsev

Kab mob Carcinoid Syndrome yog ib yam mob tsis tshua muaj uas tshwm sim rau ib tus neeg uas muaj qog nqaij hlav neuroendocrine (NET). Feem ntau, cov neeg uas muaj kab mob carcinoid syndrome twb paub tias lawv muaj NET lawm. Qee zaum, cov neeg thawj zaug kawm tias lawv muaj NET tom qab lawv kuaj pom tias muaj kab mob carcinoid syndrome.

Qhov zoo tshaj plaws yog tias NETs kho tau. Kev paub tias koj muaj carcinoid syndrome yog thawj kauj ruam los nrhiav seb koj puas muaj mob qog noj ntshav thiab, yog tias muaj, yuav kho nws li cas. Yog li, yog tias koj tau kuaj pom tias muaj carcinoid syndrome, tsis txhob ntshai tham nrog koj tus kws kho mob thiab nug seb cov kauj ruam tom ntej yog dab tsi los xyuas kom meej tias koj puas muaj NETs. Qhov tseem ceeb tshaj plaws yog kom kuaj pom thiab kho thaum ntxov.

Nco ntsoov tias, koj tsis yog tib tug xwb. Hauv qhov xwm txheej zoo li no, nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li cov lus qhia kho mob thiab nrhiav kev txhawb nqa los ntawm koj tsev neeg.

` Carcinoid syndrome, cov qog nqaij hlav neuroendocrine, NETs, ​​​​serotonin, cov tsos mob, mob qog noj ntshav, cov tshuaj hormones