Koj puas muaj tej pob lossis tej pob txawv txawv ntawm koj daim tawv nqaij? Qhov no puas yog Cutaneous B-Cell Lymphoma?

Peb daim tawv nqaij yog ib yam zoo kawg nkaus, puas yog? Qee zaum cov pob me me thiab cov pob me me tuaj thiab ploj mus. Tab sis qee zaum koj yuav xav tsis thoob me ntsis txog qhov tshiab lossis pob ntawm koj daim tawv nqaij, lossis ib qho uas tau ntev lawm uas tsis tau kho. Thaum lub sijhawm zoo li no, peb yuav tsum ceev faj me ntsis. Vim tias, txawm tias tsis tshua muaj heev, cov kev hloov pauv ntawm daim tawv nqaij kuj tuaj yeem yog ib qho tsos mob ntawm tus mob hnyav. Hnub no peb yuav tham txog tus kab mob tawv nqaij uas tsis tshua muaj, tab sis tseem ceeb heev uas yuav tsum paub txog. Qhov ntawd yog ib qho mob hu ua cutaneous B-cell lymphoma, lossis '(Cutaneous B-Cell Lymphoma)'.

Cutaneous B-Cell Lymphoma yog dab tsi?

Hais yooj yim xwb, Cutaneous B-Cell Lymphoma (CBCL) yog ib hom mob qog noj ntshav uas pib hauv koj daim tawv nqaij. Nws tsis tshua muaj. Nws yog ib pawg mob qog noj ntshav hu ua lymphoma. Tab sis qhov tshwj xeeb yog tias nws pib sab nraud ntawm peb cov qog ntshav, hauv daim tawv nqaij. Yog vim li ntawd nws thiaj hu ua extranodal lymphoma.

Feem ntau, tus kab mob "CBCL" no tshwm sim ua ib qho chaw, pob khaus, lossis pob ntawm daim tawv nqaij. Cov no loj hlob qeeb heev. Nws tuaj yeem siv sijhawm ntau lub hlis, txawm tias ntau xyoo, rau lawv kom loj hlob. Tsis tas li ntawd, lawv tsis tshua kis mus rau lwm qhov ntawm lub cev. Ib txhia neeg kuj hu nws tias "(B-cell skin lymphoma)". Yog li, yog tias koj pom qee yam tshiab lossis txawv ntawm koj daim tawv nqaij, nws yog ib lub tswv yim zoo kom ua tib zoo mloog nws.

Cov kab mob lymphoma no loj hlob li cas? Cov qe ntshav B yog dab tsi?

Tam sim no tej zaum koj yuav xav paub tias vim li cas qee yam zoo li no thiaj tshwm sim. Yog hais qhov tseeb, cov kws tshawb fawb tseem tsis tau paub qhov ua rau muaj qhov 'CBCL' no. Tab sis muaj ib qho meej: nws tsis yog los ntawm noob caj noob ces lossis kis tau.

Nws pib nrog cov qe ntshav dawb hu ua lymphocytes. Cov lymphocytes no yog cov tswv cuab tseem ceeb heev ntawm peb lub cev tiv thaiv kab mob. Lawv zoo li cov tub rog uas tiv thaiv peb lub teb chaws. Muaj ob hom lymphocytes tseem ceeb: T-cells thiab B-cells. Thaum B-cells pib loj hlob ntau dhau yam tsis muaj kev tswj hwm, qhov mob no hu ua B-cell lymphoma tshwm sim. Hais yooj yim, peb cov cells mus vwm me ntsis thiab dhau los ua cov cell mob qog noj ntshav.

Cov hom mob cutaneous B-cell lymphoma tseem ceeb yog dab tsi?

Muaj plaub hom "(CBCL)" tseem ceeb. Cov no raug faib ua pawg raws li cov cell zoo li cas hauv qab lub tshuab microscope. Txhua hom yuav zoo li txawv ntawm daim tawv nqaij thiab tej zaum yuav xav tau kev kho mob sib txawv.

1. Kab mob qog ntshav hauv cov tawv nqaij thawj zaug:

• Qhov no yog hom `(CBCL)` uas pom ntau tshaj plaws.
• Feem ntau, lawv tshwm sim rau ntawm lub taub hau, caj dab, lossis hauv siab / lub cev.
• Nws zoo li xim av liab, pob khaus nce siab lossis pob khaus ntawm daim tawv nqaij .
• Qhov no yog qhov loj heev, yuav loj hlob mus rau ntau lub hlis, tej zaum ntau xyoo.

2. Kab mob qog nqaij hlav B-cell lymphoma hauv daim tawv nqaij thawj zaug:

• Qhov no kuj yog ib hom uas loj hlob zoo.
• Feem ntau nws zoo li cov qhov txhab liab dawb, cov qog, lossis cov qog nqaij hlav .
• Nws feem ntau tshwm sim rau ntawm lub cev lossis caj npab.

3. Mob qog ntshav loj B-cell lymphoma ntawm daim tawv nqaij thawj zaug, hom ceg:

• Qhov no me dua li ob hom kab no, tab sis nws loj hlob sai dua. Qhov ntawd txhais tau tias nws loj hlob sai, hauv ob peb lub lis piam lossis ob peb lub hlis.
• Feem ntau nws tshwm sim ua ib lossis ntau lub qog lossis cov qog ntawm ob txhais ceg, caj npab, lossis hauv siab / lub cev.

4. Primary cutaneous diffuse large B-cell lymphoma, lwm yam:

• Qhov no yog ib hom tsiaj tsis tshua muaj thiab nruj heev.
• Qhov tsos yuav txawv, tab sis feem ntau nws pib ntawm lub taub hau, lub cev, thiab ceg.

Leej twg yuav muaj tus kab mob no ntau tshaj? Nws tshwm sim ntau npaum li cas?

Qhov tseeb, tus mob no hu ua "(CBCL)" tuaj yeem tshwm sim rau txhua tus neeg. Tsis muaj qhov sib txawv ntawm poj niam txiv neej, tsis muaj hnub nyoog sib txawv, thiab nws tau pom tias tshwm sim rau ntau haiv neeg sib txawv. Yog li, nws nyuaj rau xav tias, "Qhov no yuav tsis tshwm sim rau kuv."

Tiam sis, tsis txhob ntshai. Qhov no yog ib qho mob tsis tshua muaj. Xav txog nws, yog tias koj coj qhov nruab nrab ntawm ib lab tus tib neeg, tsuas yog plaub tus ntawm lawv yuav muaj qhov no. Yog li ntawd, koj tsis tas yuav ntshai thiab xav tias qhov no yog "(CBCL)" lub sijhawm koj pom qee yam txawv txawv ntawm koj daim tawv nqaij. Txawm li cas los xij, yog tias koj muaj kev tsis ntseeg, nws yog qhov zoo los nrhiav kev pab kho mob.

Cov tsos mob yog dab tsi? Saib seb koj puas muaj cov tsos mob no thiab

Cov tsos mob tseem ceeb ntawm '(CBCL)' yog kev hloov pauv ntawm daim tawv nqaij. Cov no tuaj yeem tshwm sim ntau txoj hauv kev:

• Mob pob khaus
• Ib lub pob los yog pob ntawm daim tawv nqaij
• Ib lub pob me me (nodule los yog tumor)

Cov no tuaj yeem yog xim liab, xim ntshav, lossis xim av. Qee qhov yog tsa thiab khov kho, tab sis du. Cov no hu ua papules. Lwm cov yog tiaj tus, zoo li cov tawv nqaij tuab. Cov no hu ua plaques. Cov pob loj dua kuj hu ua nodules lossis tumors.

Tej zaum yuav muaj ib qho chaw/lub qog xwb, lossis tej zaum yuav muaj ntau lub. Tsis tas li ntawd, tej zaum lawv yuav tshwm sim rau ib qho chaw ntawm lub cev lossis ntau qhov chaw. Tej zaum lawv yuav nyob ze rau ib leeg, lossis nyob deb heev.

Xav txog seb, txiv ntxawm Sunil muaj ib qho me me liab ntawm nws txhais tes tau ntau lub hlis. Nws xav tias nws tsuas yog khawb xwb. Tab sis nws maj mam loj zuj zus thiab zoo li ib lub pob. Qhov ntawd yog qhov uas yuav yog ib qho cim qhia ntxov ntawm qhov no.

Tsis tshua muaj neeg yuav muaj lwm yam tsos mob. Cov no kuj hu ua "B tsos mob". Cov no suav nrog:

• Kub taub hau uas los tsis muaj laj thawj.
• Tawm hws ntau dhau thaum hmo ntuj.
• Kev o ntawm cov qog ntshav hauv caj dab, qhov tso, lossis qhov chaw mos.
• Poob phaus yam tsis muaj laj thawj.

Qhov muaj cov "B nta" no txhais tau tias tus kab mob yuav kis tau mus ntxiv me ntsis lawm. Txawm li cas los xij, cov no tsis tshua muaj nyob hauv '(CBCL)'.

Cov kws kho mob kuaj mob li cas?

Muaj coob tus neeg ncua kev nrhiav kev kho mob vim tias cov pob thiab cov pob uas tshwm sim ntawm daim tawv nqaij hauv CBCL tuaj yeem zoo li pob txuv ib txwm muaj, kab tom, ua xua, khawb, lossis lwm yam mob ntawm daim tawv nqaij xws li eczema lossis psoriasis. Txawm li cas los xij, yog tias koj muaj qee yam txawv txawv ntawm koj daim tawv nqaij uas tsis kho, koj yuav tsum mus ntsib kws kho mob, tshwj xeeb tshaj yog kws kho mob tawv nqaij.

Tus kws kho mob yuav ua qhov kev kuaj xyuas lub cev kom zoo ua ntej. Lawv yuav saib txhua qhov chaw ntawm koj lub cev thiab soj ntsuam seb puas muaj qhov tsis zoo.

Tom qab ntawd, txhawm rau kom paub tseeb tias yog tus kab mob, yuav tsum tau kuaj daim tawv nqaij, uas txhais tau tias yuav tsum tau muab ib daim tawv nqaij me me los ntawm thaj chaw tsis zoo thiab kuaj xyuas nws. Daim tawv nqaij me me no raug kuaj hauv lub tshuab microscope los ntawm tus kws kho mob tshwj xeeb ("pathologist") kom pom tias puas muaj cov hlwb qog noj ntshav, thiab yog tias muaj, lawv yog hom twg. Kev kuaj daim tawv nqaij yog tib txoj kev los qhia meej tias nws puas yog "lymphoma ntawm daim tawv nqaij" thiab nws yog hom twg.

Yuav kom paub seb tus mob qog noj ntshav puas tau kis mus rau lwm qhov, koj tus kws kho mob yuav kom koj kuaj ntxiv ('staging tests'). Tej zaum yuav muaj xws li:

• Kev kuaj ntshav.
• Kev kuaj duab xws li CT scan lossis PET scan.
• Kev kuaj mob pob txha.
• Kev kuaj mob ntawm cov qog ntshav hauv lub cev.

Cia peb kawm txog cov theem thiab kev sib kis ntawm tus kab mob.

Theem ntawm tus kab mob (CBCL) yog qhov ntsuas seb tus mob qog noj ntshav puas tau kis mus rau lwm qhov thiab nws tau kis mus deb npaum li cas. Theem no tseem ceeb heev vim nws txiav txim siab txoj kev kho mob. Koj tus kws kho mob yuav piav qhia rau koj tias tus kab mob nyob rau theem twg thiab nws yuav cuam tshuam li cas rau koj.

• Theem 1E: Tus "E" sawv cev rau "extranodal," txhais tau tias sab nraum cov qog ntshav. Nyob rau theem no, tus mob qog nqaij hlav tsuas yog nyob rau ntawm daim tawv nqaij thiab tsis tau kis mus rau lwm qhov chaw. Yog tias tsis muaj cov tsos mob "B" ntxiv, xws li kub taub hau lossis poob phaus, qhov no kuj hu ua "Theem 1AE."

Yog tias "CBCL" tau kis mus rau lwm qhov, cov kws kho mob siv lub tshuab hu ua "TNM staging system".

• Qog (T): Tus ntawv "T" txhais tau tias muaj pes tsawg daim tawv nqaij, pob, lossis qog ntawm daim tawv nqaij, lawv loj npaum li cas, thiab qhov chaw uas lawv nyob. Qhov no suav txij li 1 txog 3 (los ntawm qhov tsawg tshaj plaws mus rau qhov hnyav tshaj plaws).
• Cov Nodes (N):Tus ntawv "N" qhia seb cov qog ntshav hauv lub cev puas raug mob, muaj pes tsawg, thiab nyob qhov twg. Qhov no kuj suav txij li 0 txog 3.
• Kev kis mus rau lwm qhov (Metastasis): Tus ntawv "M" qhia seb tus mob lymphoma puas tau kis mus dhau ntawm daim tawv nqaij lossis cov qog ntshav (`M1`) lossis tsis tau (`M0`). `(Metastasis)` txhais tau tias tus mob cancer tau kis mus rau cov kabmob nyob deb.

Cov kev kho mob yog dab tsi? Puas kho tau?

Kev kho mob rau '(CBCL)' nyob ntawm hom kab mob thiab theem ntawm tus kab mob. Feem ntau nws tuaj yeem kho tau, tshwj xeeb tshaj yog nyob rau hauv cov ntaub ntawv siab dua. Txawm li cas los xij, qee zaum tus kab mob tuaj yeem 'rov qab'.

Muaj ntau txoj kev xaiv kho mob:

• Kev saib xyuas tas li: Qee zaum uas tus kab mob loj hlob tuaj thiab tsis ua rau muaj teeb meem loj, cov kws kho mob yuav siv txoj hauv kev "saib thiab tos". Uas yog, lawv saib xyuas tus kab mob kom txog thaum pib kho mob.
• Kev Kho Mob Qog Noj Ntshav: Muab cov tshuaj uas tua cov hlwb qog noj ntshav. Cov no yuav noj ua cov tshuaj ntsiav lossis muab ua cov tshuaj txhaj.
• Cov tshuaj siv rau sab nraud lossis cov tshuaj txhaj: Cov tshuaj xws li corticosteroids tuaj yeem siv rau ntawm daim tawv nqaij lossis txhaj ncaj qha rau hauv lub qog.
• Cov tshuaj monoclonal antibodies: Cov tshuaj zoo li '(Rituximab)' yog ib feem ntawm pawg no. Cov no ua haujlwm ua kev kho mob tsom mus rau thiab rhuav tshem B-cell.
• Kev Kho Mob Hluav Taws Xob: Kev siv cov hluav taws xob muaj zog heev los tua cov hlwb qog noj ntshav. Qhov no feem ntau zoo rau cov qog nqaij hlav hauv ib cheeb tsam.
• Kev phais tshem tawm: Qee zaum, yog tias muaj ib lub qog xwb, nws tuaj yeem raug tshem tawm tag nrho los ntawm kev phais.

Koj tus kws kho mob yuav nrog koj tham txog txoj kev kho mob uas zoo tshaj plaws rau koj.

Puas muaj ib txoj kev los tiv thaiv qhov no kom tsis txhob tshwm sim?

Tu siab kawg li, vim tias qhov ua rau muaj tus kab mob '(CBCL)' tseem tsis tau paub meej, tsis muaj txoj hauv kev uas ua pov thawj tias yuav tiv thaiv tau nws. Yog li ntawd, qhov zoo tshaj plaws uas peb ua tau yog paub txog tej kev hloov pauv txawv txawv hauv peb daim tawv nqaij thiab nrhiav kev kho mob tam sim ntawd yog tias peb pom dab tsi.

Kev kwv yees yog dab tsi? (Kev kwv yees)

Qhov kev kwv yees, lossis qhov kev xav, nyob ntawm ntau yam, feem ntau yog hom lymphoma thiab theem ntawm tus kab mob.

• Ob hom mob uas feem ntau pom muaj ('Primary cutaneous follicle center lymphoma' thiab 'Primary cutaneous marginal zone B-cell lymphoma'): Cov no muaj feem yuav muaj sia nyob tau tsib xyoos li ntawm 95%. Qhov ntawd txhais tau tias tsib xyoos tom qab kuaj pom tias muaj mob no, 95 ntawm 100 tus neeg mob no tseem muaj sia nyob. Qhov no yog ib qho kev hloov pauv zoo heev.
• Cov hom mob hnyav tshaj plaws ('Primary cutaneous diffuse large B-cell lymphoma, leg type' thiab 'other'): Cov no muaj feem ciaj sia nyob tau tsib xyoos li ntawm 60%.

Cov lej no tsuas yog qhov nruab nrab xwb. Koj qhov teeb meem yuav zoo dua lossis phem dua, yog li nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob txog qhov no.

Kuv puas rov qab tau tom qab kho mob lawm?

Yog, cutaneous lymphoma tuaj yeem rov qab tshwm sim tom qab kho mob. Cov qog tuaj yeem rov qab los rau tib qho chaw lossis hauv qhov chaw tshiab. Feem ntau, tib hom subtype rov qab los. Txawm li cas los xij, tsis tshua muaj, CBCL rov qab los tuaj yeem yog kab mob thoob plaws lub cev lossis lwm hom lymphoma.

Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum tau kuaj xyuas koj daim tawv nqaij tas li ('kev kuaj xyuas daim tawv nqaij') thiab mus kuaj xyuas koj daim tawv nqaij tas li nrog kws kho mob tawv nqaij lossis lwm tus kws tshwj xeeb.

Ua ib tug neeg uas muaj CBCL, koj yuav saib xyuas koj txoj kev noj qab haus huv li cas?

Yog tias koj muaj (CBCL) lossis tau muaj nws ua ntej thiab rov zoo lawm, nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li koj tus kws kho mob cov lus qhia. Koj yuav tsum tau mus kuaj mob kom paub tseeb tias tus kab mob tsis rov tshwm sim dua.

Cov kev kuaj no ua ntau zaus npaum li cas yuav txawv nyob ntawm hom CBCL thiab nws ua haujlwm hnyav npaum li cas. Nws yuav yog txhua ob peb lub lis piam, txhua ob peb lub hlis, lossis ib xyoos ib zaug. Cov kev teem sijhawm tom qab no yuav suav nrog kev kuaj tawv nqaij, kev kuaj ntshav, kev thaij duab x-ray, lossis kev kuaj nqaij.

Cov lus nug uas koj yuav tsum nug koj tus kws kho mob

Yog tias koj raug kuaj pom tias muaj '(Cutaneous B-Cell Lymphoma)', tsis txhob hnov ​​​​qab nug koj tus kws kho mob cov lus nug no:

• Kuv muaj hom `(CBCL)` dab tsi?
• Qhov no nyob rau theem twg?
• Koj pom zoo kom siv hom kev kho mob twg?
• Cov kev mob tshwm sim thiab kev pheej hmoo ntawm cov kev kho mob ntawd yog dab tsi?
• Kuv qhov kev kwv yees yog li cas?
• Yuav siv sijhawm ntev npaum li cas thiaj paub tias kev kho mob puas ua tiav lossis tsis ua tiav?
• Kuv yuav tsum mus ntsib koj ntau npaum li cas kom paub tseeb tias tus kab mob lymphoma tsis rov qab los?

Cov lus teb rau cov lus nug no yuav pab koj nkag siab zoo dua txog tus kab mob thiab cov kauj ruam tom ntej.

Cov Lus Qhia Txog Qhov Peb Tau Tham Txog

Cutaneous B-Cell Lymphoma yog ib hom mob qog noj ntshav tsawg uas pib hauv cov hlwb hu ua lymphocytes hauv daim tawv nqaij.

• Feem ntau cov mob no loj hlob qeeb qeeb thiab tsis kis mus rau lwm qhov ntawm lub cev. Txawm li cas los xij, qee hom mob no tuaj yeem ua rau mob hnyav thiab kis mus rau lwm qhov.
• Yog koj pom ib lub pob tshiab, ib qho chaw, lossis ib qho pob khaus ntawm koj daim tawv nqaij uas tsis zoo , tsis txhob tsis quav ntsej . Mus ntsib kws kho mob, tshwj xeeb yog kws kho mob tawv nqaij, tam sim ntawd.
• Ntau hom CBCL tuaj yeem kho tau nrog kev kuaj pom thaum ntxov thiab kev kho mob kom zoo.
• Vim tias tus kab mob yuav rov tshwm sim tom qab kho mob tas,Nws yog ib qho tseem ceeb uas yuav tsum tau mus kuaj mob raws li lub sijhawm teem tseg raws li tus kws kho mob tau hais.

Nco ntsoov, cov ntaub ntawv no tsuas yog rau kev kawm xwb. Yog tias koj muaj teeb meem kev noj qab haus huv, nws yog qhov zoo tshaj plaws los nrhiav kev pab kho mob.

` Mob qog nqaij hlav B-Cell Lymphoma, Mob qog nqaij hlav ntawm daim tawv nqaij, Lymphoma, B-Cell, Mob qog ntawm daim tawv nqaij, Mob tawv nqaij