Puas muaj ib qho chaw txawv txawv ntawm koj daim tawv nqaij? Tej zaum nws yog DFSP (Dermatofibrosarcoma Protuberans)!

Koj puas tau pom ib lub pob me me lossis xim tsis zoo ntawm koj daim tawv nqaij? Qee zaum peb tsis quav ntsej txog nws, puas yog? Tab sis qee zaum txawm tias qee yam me me li no kuj tuaj yeem ua rau koj txhawj xeeb txog. Hnub no, peb yuav tham txog ib hom mob qog nqaij hlav uas tsis tshua muaj tab sis tseem ceeb. Nws hu ua Dermatofibrosarcoma Protuberans , lossis luv luv DFSP .

DFSP (Dermatofibrosarcoma Protuberans) yog dab tsi?

Hais yooj yim xwb, DFSP yog ib hom mob qog nqaij hlav uas loj hlob qeeb qeeb, tab sis tsis tshua muaj. Nws pib hauv txheej nruab nrab ntawm peb daim tawv nqaij, lub dermis . Tej zaum koj yuav hnov ​​​​​​tus kws kho mob hu nws tias DFSP.

Vim tias qhov no yog ib hom mob qog nqaij hlav uas loj hlob qeeb, nws tsis tshua kis mus rau lwm qhov ntawm lub cev. Txawm li cas los xij, nws tsis yog lub tswv yim zoo kom tsis quav ntsej nws. Nws yog ib qho tseem ceeb heev kom tau txais kev kho mob kom zoo thiab tshem tawm cov qog no. Tsuas yog thaum ntawd tus mob qog nqaij hlav thiaj li tsis rov qab los (rov tshwm sim dua) lossis kis mus rau lwm qhov ntawm lub cev (mob qog nqaij hlav metastatic). Yog tias kho kom zoo, tus neeg uas muaj DFSP muaj lub sijhawm zoo heev los kho.

Qhov DFSP no puas yog ib qho qog nqaij hlav xwb? Los yog nws puas yog mob qog nqaij hlav?

Tsis yog, DFSP tsis yog ib qho mob qog nqaij hlav xwb. Nws yog ib qho mob qog nqaij hlav phem . Yog hais kom meej, nws yog ib hom mob qog nqaij hlav ntawm cov nqaij mos, ib hom mob qog nqaij hlav ntawm cov nqaij mos . Sarcomas yog cov mob qog nqaij hlav uas tshwm sim hauv cov chaw xws li cov leeg nqaij, cov rog, thiab daim tawv nqaij. Qee zaum, lawv kuj tuaj yeem cuam tshuam rau cov pob txha.

DFSP puas kis tau (metastasize) mus rau lwm qhov ntawm lub cev?

DFSP feem ntau tsis yog ib hom mob qog nqaij hlav uas kis tau sai heev thoob plaws lub cev. Txawm li cas los xij, tsis tshua muaj, kwv yees li ib ntawm 20 tus neeg uas muaj DFSP tuaj yeem muaj mob qog nqaij hlav kis mus rau lwm qhov chaw uas nws pib. Qhov no hu ua mob qog nqaij hlav kis mus rau lwm qhov chaw (metastatic cancer) .

Qhov no yuav kis tau yooj yim yog tias tsis kho, lossis yog tias mob qog noj ntshav tau kis mus tob rau hauv daim tawv nqaij, mus rau hauv cov nqaij rog thiab cov leeg.

Lwm yam yog, txawm hais tias qhov ua rau tsis paub meej, yog tias DFSP tshwm sim thaum cev xeeb tub, nws yuav hnyav dua.

Tsis tas li ntawd xwb, muaj ib co neeg me me uas muaj DFSP tuaj yeem tsim tau ib hom mob hnyav dua, kis tau sai dua hu ua fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS) . Txawm tias cov qog DFSP-FS no raug phais tshem tawm los xij, lawv yuav rov qab los dua thiab tuaj yeem kis mus rau lwm qhov chaw.

Tus mob no hu ua DFSP ntau npaum li cas?

DFSP yog ib hom mob qog noj ntshav uas tsis tshua muaj. Thoob ntiaj teb, nws tsuas cuam tshuam rau kwv yees li plaub tus neeg hauv ib lab tus neeg hauv ib xyoos. DFSP suav txog li ntawm 1% thiab 6% ntawm tag nrho cov qog nqaij mos.

Kab mob qog no feem ntau tshwm sim rau cov neeg laus hnub nyoog ntawm 20 thiab 50 xyoo. Txawm li cas los xij, cov menyuam yaus kuj tuaj yeem muaj tus kab mob qog no. Ib txhia menyuam mos tuaj yeem muaj DFSP thaum yug los. Kev tshawb fawb tau qhia tias cov neeg dub muaj feem yuav muaj nws ntau dua li cov neeg ntawm lwm haiv neeg.

Cov hom DFSP tseem ceeb yog dab tsi?

Cov kws kho mob pathologists, cov kws kho mob uas kuaj cov nqaij ntawm lub cev hauv qab lub tshuab microscope, tuaj yeem qhia koj meej tias koj muaj hom DFSP twg los ntawm kev kuaj cov cell. Muaj ntau hom tseem ceeb:

• Cov qog nqaij hlav Bednar (tseem hu ua pigmented DFSP): Cov hom hlwb no muaj ntau melanin , cov pigment uas muab nws cov xim rau daim tawv nqaij. Qhov no yog vim li cas cov qog nqaij hlav no tuaj yeem tshwm sim ntau yam xim, suav nrog liab, xim av, xiav, thiab ntshav. Hom no suav txog li 5% ntawm kev kuaj mob DFSP.
• Mob qog nqaij hlav loj heev (giant cell fibroblastoma): Hom no yog tus yam ntxwv los ntawm qhov muaj cov qog nqaij hlav loj heev. Hom no kuj hu ua juvenile DFSP vim tias nws feem ntau tshwm sim rau cov menyuam yaus thiab cov hluas.
• Fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS): Raws li tau hais ua ntej, qhov no yog ib hom mob sarcoma uas sib kis sai thiab sib kis sai.
• Myxoid DFSPs: Cov no yog ua los ntawm ib hom nqaij sib txuas uas tsis zoo hu ua myxoid stroma. Hom DFSP no tsis tshua muaj.

Dab tsi ua rau DFSP?

Qhov xav tsis thoob yog, 9 ntawm 10 tus neeg uas muaj DFSP muaj kev hloov pauv caj ces uas ua rau muaj tus mob no . Qhov kev hloov pauv caj ces no tshwm sim hauv peb cov hlwb tom qab peb yug los. Qhov no txhais tau tias DFSP tsis yog los ntawm qhov tsis zoo caj ces uas tau txais los ntawm peb niam peb txiv.

Cov yam uas ua rau muaj kev pheej hmoo ntawm DFSP yog dab tsi?

Ntxiv rau haiv neeg, kev raug mob ntawm daim tawv nqaij lossis qhov caws pliav tuaj yeem ua rau muaj kev pheej hmoo ntawm kev mob DFSP. Muaj ntau txoj hauv kev uas daim tawv nqaij tuaj yeem raug mob:

• Kub hnyiab
• Kev kho mob hluav taws xob
• Cov kev phais mob
• Cov duab kos

Xav txog seb, koj puas tau muaj qhov kub hnyiab loj thiab muaj qhov caws pliav loj. Los yog, koj tau txais kev kho mob hluav taws xob rau lwm yam kab mob. Thaum daim tawv nqaij raug puas tsuaj los ntawm tej yam zoo li no, muaj feem me me uas tus mob zoo li DFSP yuav tshwm sim yav tom ntej, txawm tias tsis tshua muaj. Yog vim li ntawd peb yuav tsum paub txog kev hloov pauv ntawm daim tawv nqaij.

Cov tsos mob ntawm DFSP yog dab tsi?

Cov tsos mob thaum ntxov ntawm DFSP tsis pom tseeb heev uas peb yuav tsis pom lossis tsis pom lawv. Cov qog no feem ntau tshwm sim rau ntawm lub hauv siab, nraub qaum, xub pwg nyom, plab, lossis pob tw. Lawv kuj tuaj yeem tshwm sim rau ntawm caj npab, ceg, taub hau, thiab sab hauv qhov ncauj.

Thaum xub thawj, koj yuav pom ib qho me me zoo li qhov mob ntawm daim tawv nqaij.Nws tiaj tus thiab tsis mob. Tej zaum yuav zoo li ntxhib me ntsis thaum kov, thiab xim yuav hloov me ntsis.

Rau cov menyuam mos thiab cov menyuam yaus, DFSP zoo li lub cim yug los . Cov chaw no feem ntau dav li ib nrab nti mus rau ob nti (1 txog 5 centimeters).

Cov tsos mob ntawm DFSP pib pom tseeb thaum tus mob qog noj ntshav loj hlob tuaj. Thaum tus mob qog noj ntshav loj hlob tuaj, nws thawb mus rau hauv txheej sab saud ntawm daim tawv nqaij (epidermis). Qhov no ua rau cov pob tawv (nodules) tshwm sim ntawm qhov chaw ntawm daim tawv nqaij . Lo lus "protuberance" txhais tau tias "tawm mus."

Koj yuav pom cov tsos mob no hauv cov pob no:

• Nws tuaj yeem tawg lossis los ntshav tau yooj yim.
• Nws lo rau ntawm daim tawv nqaij ruaj khov (tsis tuaj yeem txav mus los tau).
• Thaum koj laus zuj zus, koj daim tawv nqaij ncab.
• Nws zoo li nyuaj rau kov, lossis zoo li roj hmab.
• Cov xim tuaj yeem yog xim av liab, xim ntshav, xiav, lossis xim liab.
• Thaum kov nws, tej zaum yuav mob me ntsis.

Puas muaj lwm yam mob uas ua rau muaj cov tsos mob zoo ib yam li DFSP?

Yog, muaj ib qho mob ntawm daim tawv nqaij uas tsis yog mob qog noj ntshav hu ua cellular dermatofibroma . Qhov no zoo li DFSP heev, tshwj xeeb tshaj yog thaum pib. Cellular dermatofibromas yog cov qog nqaij mos mos uas tsis muaj teeb meem. Feem ntau lawv tshwm sim rau ntawm ob txhais ceg. Qee zaum lawv tuaj yeem khaus thiab mob. Feem ntau dermatofibromas tsis tas yuav kho. Txawm li cas los xij, nws yog ib qho tseem ceeb kom tsis txhob ua rau ob qho no tsis meej pem, yog li nws yog ib qho tseem ceeb kom mus ntsib kws kho mob yog tias koj pom muaj dab tsi tshiab rau ntawm koj daim tawv nqaij.

Yuav kuaj mob DFSP (Dermatofibrosarcoma Protuberans) li cas?

Cov kws kho mob tawv nqaij yuav kuaj pom DFSP, uas yog cov kws kho mob uas tau kawm tshwj xeeb txog mob qog nqaij hlav thiab cov kab mob ntawm daim tawv nqaij. Koj tus kws kho mob yuav xub muab ib qho qauv me me ntawm daim tawv nqaij lossis qhov chaw thiab xa mus rau chav kuaj mob kom kuaj (kev kuaj daim tawv nqaij) . Tag nrho cov pob yuav raug tshem tawm thiab xa mus rau chav kuaj mob. Cov kws kho mob tom qab ntawd yuav saib cov ntaub so ntswg hauv qab lub tshuab microscope kom pom tias nws puas muaj cov hlwb qog nqaij hlav.

Yog tias qhov kev kuaj mob ntawm daim tawv nqaij lees paub tias koj muaj DFSP, ces koj yuav raug hais kom ua MRI scan . Qhov no yuav pab txiav txim siab qhov loj me ntawm lub qog thiab nws tau kis mus rau hauv daim tawv nqaij tob npaum li cas. Cov ntaub ntawv no tseem ceeb heev rau kev npaj kho mob.

Cov kev kho mob rau DFSP (Dermatofibrosarcoma Protuberans) yog dab tsi?

Txoj kev kho mob tseem ceeb thiab zoo tshaj plaws rau DFSP yog phais tshem tawm cov qog. Cov kws kho mob tawv nqaij feem ntau siv cov txheej txheem tshwj xeeb hu ua Mohs phais kom tshem tawm cov qog DFSP. Nov yog qhov tshwm sim thaum lub sijhawm phais no:

• Ua ntej, yuav muab tshuaj loog rau hauv thaj chaw kho mob, yog li koj yuav tsis hnov ​​mob dab tsi.
• Tom qab ntawd, tus kws kho mob txiav thiab tshem tawm cov qog nqaij hlav. Tab sis tsis yog tsuas yog cov qog nqaij hlav xwb, tab sis kuj yog ib qho me me ntawm daim tawv nqaij noj qab haus huv nyob ib puag ncig nws. Qhov no hu ua ntug .
• Tom ntej no, cov npoo (ciam teb) ntawm cov ntaub so uas raug tshem tawm raug kuaj xyuas hauv qab lub tshuab microscope kom pom tias puas tseem muaj cov hlwb qog noj ntshav.
• Yog tias tseem muaj cov qog nqaij hlav ntawm ntug, tus kws kho mob yuav tshem tawm qee cov nqaij ntxiv ntawm thaj chaw uas tau ua phais dua.
• Ua li no, kev tshem tawm cov ntaub so ntswg txuas ntxiv mus txog thaum tsis pom cov qe mob qog noj ntshav ntawm ntug.
• Tom qab mob qog noj ntshav raug tshem tawm tag lawm, yuav phais kho dua tshiab yog tias tsim nyog.

Puas muaj lwm yam kev kho mob rau DFSP yam tsis tas phais?

Txawm tias cov qog DFSP raug phais tshem tawm los xij, qee zaum lawv tuaj yeem rov qab los. Tom qab kev phais dav dav ib txwm muaj, muaj 20% txog 30% lub sijhawm uas lawv yuav rov qab los hauv peb xyoos. Tom qab phais Mohs, qhov kev pheej hmoo no raug txo kom txog 4% txog 5%. Txawm li cas los xij, nws yog ib qho tseem ceeb kom ceev faj, vim tias cov qog tuaj yeem rov qab los txawm tias 10 xyoo lossis ntau dua tom qab.

Qee zaum, yog tias tus mob qog nqaij hlav tau kis mus rau lwm qhov ntawm lub cev (metastatic DFSP), lossis yog tias tus qog loj dhau lossis nyob hauv thaj chaw uas tsis tuaj yeem phais tshem tawm, cov kws kho mob siv cov tshuaj hu ua Imatinib . Cov tshuaj no kuj tseem tuaj yeem ua rau tus qog me dua, ua rau nws yooj yim dua rau kev phais tshem tawm.

Tsis tas li ntawd xwb, yog tias phais tsis tuaj yeem tshem tawm cov qog nqaij hlav tag nrho, lossis yog tias phais tsis tau li, kev kho mob hluav taws xob yuav siv tau.

Yuav ua li cas rau ib tus neeg uas muaj DFSP?

Qhov no yog xov xwm zoo kawg nkaus. Vim tias DFSP yog ib hom mob qog nqaij hlav uas loj hlob qeeb qeeb, tsis muaj zog, yog tias kho kom zoo, ntau dua 99% ntawm cov neeg yuav muaj sia nyob tau 10 xyoo lossis ntau dua. Yog li, qhov tseem ceeb tshaj plaws yog tsis txhob ntshai thiab ua raws li koj tus kws kho mob cov lus qhia.

Kuv ua tau dab tsi los txhim kho kuv txoj kev xav?

Muaj ntau yam uas koj ua tau los txhim kho koj txoj kev xav:

• Ua tib zoo kuaj koj daim tawv nqaij tsis tu ncua. Nrhiav seb puas muaj tej yam hloov tshiab, tej pob me me, lossis tej pob me me ntawm koj daim tawv nqaij. Yog koj pom dab tsi, qhia rau koj tus kws kho mob tam sim ntawd.
• Tom qab kho mob tas, mus ntsib koj tus kws kho mob kom kuaj xyuas daim tawv nqaij tsawg kawg yog txhua peb mus rau rau lub hlis rau peb xyoos thawj zaug. Tom qab ntawd mus kuaj xyuas ib xyoos ib zaug, lossis raws li koj tus kws kho mob hais.
• Txo qhov raug tshav ntuj. Cov teeb UV los ntawm lub hnub ua rau muaj kev pheej hmoo ntawm lwm yam mob qog nqaij hlav ntawm daim tawv nqaij. Yog li, hnav tshuaj pleev thaiv hnub thaum koj tawm mus rau hauv tshav ntuj, hnav khaub ncaws tiv thaiv , thiab txwv koj lub sijhawm sab nraum zoov thaum lub sijhawm kub tshaj plaws ntawm hnub.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Yog tias koj pom muaj kev hloov pauv tshiab hauv koj daim tawv nqaij, tshwj xeeb tshaj yog tias koj muaj ib qho ntawm cov hauv qab no, nco ntsoov mus ntsib kws kho mob:

• Cov pob khaus lossis cov pob me me tshiab, uas nyob ntev, lossis cov tawv nqaij tshiab loj hlob tuaj.
• Kev hloov pauv ntawm cov pob khaus, cov cim yug los, cov qhov txhab qub, lossis cov duab kos.
• Yog tias cov pob ntawm daim tawv nqaij los ntshav yooj yim.

Nco ntsoov tias, kev hloov pauv ntawm daim tawv nqaij feem ntau tsis muaj teeb meem dab tsi. Txawm li cas los xij, qee qhov kev hloov pauv tuaj yeem yog ib qho cim qhia txog mob qog nqaij hlav. Yog li, yog tias koj muaj kev tsis ntseeg, nws yog qhov zoo tshaj plaws mus ntsib kws kho mob kom daws qhov teeb meem.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Yog tias koj raug kuaj pom tias muaj DFSP, tej zaum koj yuav xav nug koj tus kws kho mob cov lus nug xws li:

• Vim li cas kuv thiaj tau tus mob qog nqaij tawv no?
• Kuv puas muaj feem yuav mob qog nqaij hlav lwm yam?
• Kev kho mob zoo tshaj plaws rau kuv yog dab tsi?
• Puas muaj kev pheej hmoo tias tus mob qog noj ntshav no yuav kis mus rau lwm qhov ntawm lub cev?
• Kuv yuav tsum tuaj kuaj mob qog noj ntshav ntau npaum li cas?

Kev paub cov lus teb rau cov lus nug no yuav pab koj nkag siab zoo dua txog tus mob thiab tuaj yeem pab koj piav qhia meej txog koj txoj kev kho mob thiab cov phiaj xwm yav tom ntej.

Thaum kawg, tej yam uas yuav tsum nco ntsoov

Txawm hais tias DFSP yog ib hom mob qog nqaij hlav uas tsis tshua muaj, nws tsis tshua muaj peev xwm kis mus rau lwm qhov ntawm lub cev. Txawm li cas los xij, kev phais mob yog qhov tseem ceeb kom tiv thaiv kev loj hlob. Kev kuaj pom thaum ntxov thiab kev kho mob kom zoo tuaj yeem txhim kho koj txoj kev xav. Yog li, ceev faj txog koj daim tawv nqaij thiab mus ntsib kws kho mob yog tias koj pom muaj dab tsi txawv txawv. Koj tsis nyob ib leeg, thiab muaj cov kws kho mob uas tuaj yeem pab koj ntawm txoj kev no.

DFSP , mob qog nqaij hlav ntawm daim tawv nqaij, mob qog nqaij hlav ntawm daim tawv nqaij, pob ntawm daim tawv nqaij, phais mob Mohs, cov tsos mob ntawm mob qog nqaij hlav, cov kab mob ntawm daim tawv nqaij