Gastrin yog dab tsi? Puas cuam tshuam rau koj cov teeb meem plab?

Koj puas tau xav txog tias muaj pes tsawg yam tshwm sim hauv peb lub cev, tshwj xeeb tshaj yog tom qab peb noj mov? Peb muaj ib pawg me me ntawm cov tshuaj xa xov hauv peb lub cev uas pab txhua yam no tshwm sim. Peb hu cov tshuaj hormones no. Hnub no peb yuav tham txog ib qho tshuaj hormones tshwj xeeb. Qhov ntawd yog gastrin. Cov gastrin no tseem ceeb heev rau kev ua haujlwm ntawm peb lub cev zom zaub mov.

Gastrin ua dab tsi tiag?

Zoo, tam sim no cia peb saib seb tus phooj ywg no hu ua Gastrin ua dab tsi rau peb lub cev. Nws muaj ntau lub luag haujlwm tseem ceeb.

• Kev tsim cov kua qaub hauv plab: Qhov tseem ceeb tshaj plaws yog qhia rau koj lub plab kom tso cov kua qaub hauv plab tawm. Cov kua qaub hauv plab no yog qhov peb hu ua hydrochloric acid. Yog tsis muaj qhov no, nws nyuaj heev rau kev zom zaub mov.
• Kev ua haujlwm ntawm cov leeg nqaij hauv plab: Gastrin kuj pab cov leeg nqaij hauv koj lub plab ua haujlwm kom zoo, uas txhais tau tias nws ua rau lub plab txav mus los, uas pab sib tov thiab zom cov zaub mov.
• Kho Dua Phab Ntsa Plab: Cov txheej sab hauv ntawm peb lub plab, uas yog cov mucosa, yuav tsum tau kho dua tshiab tas li. Gastrin kuj pab nrog qhov no thiab.
• Kev txhawb nqa lub gallbladder thiab pancreas: Gastrin, nrog rau lwm yam tshuaj hormones hu ua cholecystokinin, pab koj lub gallbladder thiab pancreas cog lus thiab tso cov kua txiv zom zaub mov.

Qhov txawv ntawm Gastrin thiab Gastric acid yog dab tsi?

Qhov no puas zoo li tsis meej pem me ntsis? Hais yooj yim xwb, nws zoo li no. Gastrin yog ib yam tshuaj hormones . Nws zoo li ib tsab ntawv. Tsab ntawv no qhia rau lub plab tias, "Okay, tam sim no tso cov kua qaub hauv plab tawm." Tom qab ntawd cov kua qaub hauv plab no ua rau cov enzyme pepsin zom zaub mov ua haujlwm. Ua ke, ob qho no tsim cov kua qaub hauv plab hauv peb lub plab. Koj puas nkag siab?

Gastrin tsim tawm qhov twg?

Gastrin feem ntau yog tsim los ntawm cov kabmob hauv peb lub cev zom zaub mov. Cov tshuaj hormone no los ntawm ib hom cell tshwj xeeb hu ua G-cells. Tsab ntawv "G" sawv cev rau "gastrin."

Feem ntau cov gastrin los ntawm koj lub plab , tshwj xeeb tshaj yog qhov qis ntawm koj lub plab (peb hu nws ua antrum). Cov G-cell no nyob hauv cov qog plab hauv phab ntsa ntawm koj lub plab. Tsis tas li ntawd, qee qhov gastrin yog tsim los ntawm duodenum, thawj feem ntawm koj txoj hnyuv me, thiab los ntawm lub txiav.

Muaj tej yam dab tsi cuam tshuam rau kev tso tawm ntawm gastrin?

Thaum koj xav txog kev noj mov, nws yog qhov xav tsis thoob tias gastrin raug tso tawm li cas! Koj paub li cas? Peb lub hlwb thiab lub cev zom zaub mov txuas nrog tas li los ntawm ib lub network tshwj xeeb ntawm cov hlab ntsha hu ua vagal nerves. Cov ntaub ntawv taug kev rov qab los ntawm cov hlab ntsha no.

Yog li, thaum koj xav txog zaub mov, cov hlab ntsha vagal hauv koj lub hlwb xa xov mus rau lub plab, hais tias, "Okay, zaub mov tuaj txog, tso gastrin thiab npaj rau kev zom zaub mov." Tom qab ntawd, thaum koj pib noj mov, cov hlab ntsha hauv koj lub plab paub tias zaub mov tau nkag mus thiab tso ntau gastrin.

Lwm yam uas ua rau lub cev tso gastrin tawm:

• Kev nce ntxiv ntawm pH ntawm lub plab (uas yog, thaum cov kua qaub qis dua).
• Cov phab ntsa plab raug rub thaum cov khoom noj nkag mus.
• Qee yam khoom noj , tshwj xeeb yog cov uas muaj protein, nkag mus rau hauv plab.

Gastrin ua rau cov kua qaub hauv plab tso tawm, uas ua rau pepsin ua haujlwm. Ua ke, cov no rhuav tshem thiab zom cov protein hauv plab. Gastrin kuj ua rau cov leeg nqaij hauv plab txav mus los.

Yuav ua li cas thiaj li tiv thaiv tau qhov tso tawm ntawm gastrin?

Thaum cov khoom noj tawm ntawm koj lub plab thiab txav mus rau hauv thawj ntu ntawm txoj hnyuv me, duodenum, theem tom ntej ntawm kev zom zaub mov pib. Thaum ntawd qhov tso tawm ntawm gastrin pib txo qis. Thaum cov khoom noj tawm hauv lub plab thiab cov kua qaub hauv plab nce ntxiv, gastrin txo qis.

Thaum cov khoom noj nkag mus rau hauv duodenum, koj lub gallbladder thiab pancreas tso lawv cov kua zaub mov tawm. Tom qab ntawd, peb lub cev zom zaub mov tso tawm lwm yam tshuaj hormones hu ua somatostatin. Cov somatostatin no tua lwm cov tshuaj hormones (xws li gastrin). Nws zoo li tua lub khawm.

Yuav ua li cas los xyuas cov qib gastrin?

Muaj kev kuaj ntshav tshwj xeeb los xyuas koj cov gastrin. Peb hu nws ua kev kuaj gastrin. Tus kws kho mob, xws li tus kws kho mob lossis tus nais maum, coj ib qho qauv ntshav me me los ntawm cov leeg ntshav hauv koj txhais caj npab thiab xa mus rau chav kuaj mob kom kuaj.

Vim li cas kuv cov gastrin theem thiaj tseem ceeb?

Cov kws kho mob yuav kuaj koj cov gastrin seb puas siab dhau . Cov gastrin qis tsis tshua muaj, tab sis cov gastrin siab tuaj yeem qhia txog qee yam kab mob thiab mob plab hnyuv.

Cov qib gastrin siab (Hypergastrinemia) txhais li cas?

Thaum cov gastrin theem siab, peb hu nws ua hypergastrinemia. Qee zaum, hypergastrinemia txhais tau tias koj muaj cov qog tsim gastrin hauv koj lub cev, hu ua gastrinomas. Cov no tuaj yeem tshwm sim hauv koj lub pancreas lossis duodenum.

Lwm lub sijhawm, hypergastrinemia txhais tau tias muaj ib yam dab tsi hauv koj lub plab uas tiv thaiv nws kom tsis txhob tsim cov kua qaub hauv plab. Thaum cov kua qaub hauv plab txo qis, cov gastrin ntau dua yuav raug tso tawm. Tsis tas li ntawd, cov cim uas feem ntau nres cov gastrin tsim tawm raug cuam tshuam.

Yuav ua li cas yog tias cov gastrin nce siab?

Yog tias koj cov gastrin siab, qhov ntau ntawm cov kua qaub hauv koj lub plab thiab duodenum tuaj yeem siab dhau. Cov kua qaub ntau dhau tuaj yeem ua rau lub txheej tiv thaiv ntawm koj lub plab thiab duodenum puas tsuaj, ua rau muaj mob qog, tseem hu ua kab mob peptic ulcer.

Tsis tas li ntawd xwb, yog koj muaj kua qaub ntau dhau hauv plab ces yuav ua rau koj muaj mob hu ua GERD (Gastroesophageal Reflux Disease), uas yog ib yam mob uas kua qaub nce mus rau hauv caj pas mus ntev. Yog koj muaj mob peptic ulcer lossis GERD thiab nws tsis zoo dua yog koj noj tshuaj, koj tus kws kho mob yuav kuaj koj cov gastrin.

Tej yam mob twg uas yuav cuam tshuam nrog cov gastrin ntau dhau?

Yog koj muaj gastrinomas, koj cov gastrin thiab gastric acid ob qho tib si yuav siab dua. Gastrinomas yog ib hom qog nqaij hlav pancreatic neuroendocrine (PET) uas tso gastrin tawm. Lawv tuaj yeem yog mob qog noj ntshav lossis tsis yog mob qog noj ntshav.

Cov mob uas ua rau muaj gastrinomas:

• Zollinger-Ellison syndrome.
• Ntau yam endocrine neoplasia hom 1 (MEN1).

Cov mob uas gastrin thiab gastric acid nce siab yam tsis muaj gastrinomas:

• Mob raum tsis ua haujlwm ntev.
• Kev thaiv qhov tawm ntawm lub plab (GOO).

Yog tias koj cov kua qaub hauv plab tsis tshua muaj, tej zaum koj yuav muaj cov gastrin ntau tab sis cov kua qaub hauv plab tsis tshua muaj. Qhov no tej zaum yuav yog vim muaj mob gastritis atrophic, uas yog ib qho mob uas cov hlwb uas tsim cov kua qaub hauv plab raug rhuav tshem.

Cov ua rau mob atrophic gastritis yog:

• Kev kis tus kab mob H. pylori.
• Cov kab mob autoimmune (piv txwv li, autoimmune atrophic gastritis).

Lwm yam ua rau cov kua qaub hauv plab tsawg dua:

• Cov tshuaj uas thaiv cov kua qaub, xws li H2 blockers lossis proton pump inhibitors (PPIs).
• Kev phais tshem tawm lossis txiav cov hlab ntsha vagal (vagal nerve).

Kuv yuav tsum ua li cas yog tias kuv muaj cov tsos mob ntawm cov gastrin siab?

Yog tias koj muaj cov tsos mob ntawm lub plab, tshwj xeeb tshaj yog tias lawv tshwm sim ntau zaus lossis tau muaj ntev lawm, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib kws kho mob. Nov yog qee cov tsos mob uas yuav cuam tshuam nrog kev nce gastrin:

• Mob plab los yog mob ntswj.
• Mob hauv siab tas li thiab zom zaub mov tsis zoo.
• Mob plab los yog khoom noj daig hauv caj pas.
• Mob caj pas tas li thiab suab nrov.
• Mob raws plab tas li.
• Teeb meem zom zaub mov.

Cov tsos mob no yuav qhia tau tias koj muaj cov kua qaub ntau hauv plab, lossis koj muaj mob gastritis atrophic, mob peptic ulcer, lossis GERD. Qhov no yuav lossis tsis muaj feem cuam tshuam nrog gastrin. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum kuaj mob thiab kho cov mob no kom raug.

Nco ntsoov tias, yog koj muaj cov tsos mob zoo li no, tsis txhob sim kuaj koj tus kheej los ntawm kev nrhiav cov ntaub ntawv hauv internet. Zoo tshaj plaws yog mus ntsib kws kho mob thiab tau txais kev qhia.

Cov Lus Qhia Txog Kev Coj Mus Tsev

Zoo, yog li cia peb saib qee yam yooj yim uas yuav tsum nco ntsoov txog gastrin uas peb tau tham txog.

• Gastrin yog ib yam tshuaj hormones tseem ceeb hauv peb lub cev zom zaub mov .
• Nws lub luag haujlwm tseem ceeb yog qhia rau lub plab kom tso cov kua qaub hauv plab .
• Yog tias koj lub plab kua qaub ntau dhau los yog tsawg dhau , nws yuav muaj feem cuam tshuam nrog gastrin.
• Yog tias koj muaj cov tsos mob ntawm lub plab, lossis cov mob uas tsis zoo dua nrog kev kho mob, tus kws kho mob yuav kuaj koj cov gastrin.
• Qee zaum cov gastrin siab tuaj yeem yog ib qho cim qhia txog mob, yog li nws yog ib qho tseem ceeb uas yuav tsum nrhiav kev pab kho mob yog tias koj muaj cov tsos mob.

Yog li ntawd, Gastrin yog ib yam me me tab sis muaj zog uas ua haujlwm ntsiag to hauv peb lub cev. Kev paub txog qhov no yuav tseem ceeb heev rau koj txoj kev noj qab haus huv. Yog tias koj muaj lus nug ntxiv, tsis txhob yig nug koj tus kws kho mob.

Gastrin , cov tshuaj hormones, kev zom zaub mov, kua qaub hauv plab, mob plab hnyuv, GERD, hypergastrinemia