Koj tus menyuam puas ua txuj ua li menyuam yaus loj ua ntej nws muaj hnub nyoog? Cia peb kawm txog Precocious Puberty.

Koj puas tau xav tias koj tus ntxhais lossis tus tub ua txuj ua li menyuam yaus ua ntej lawv lub sijhawm, lossis nws lub cev hloov pauv? Muaj ib txhia menyuam yaus yeej muaj cov cim qhia tias lawv laus ua ntej lawv lub sijhawm. Hnub no peb yuav tham txog qhov mob no hu ua 'precocious puberty' lossis raws li cov kws kho mob hu ua, '(Precocious Puberty)'. Tsis txhob txhawj, peb yuav tham txog qhov no yooj yim xwb.

Yog li ntawd, qhov no yog dab tsi thaum ntxov puberty?

Lub sijhawm laus yog lub sijhawm uas lub cev ntawm ib tug menyuam yaus hloov pauv loj heev thiab lawv maj mam pib tsim cov yam ntxwv ntawm ib tug neeg laus. Qhov no yog ib yam ntuj tsim. Feem ntau, muaj ib feem me me ntawm koj tus menyuam lub hlwb hu ua hypothalamus. Qhov no yog qhov chaw uas hypothalamus pib. Nws tso tawm qee yam tshuaj hu ua cov tshuaj hormones. Cov tshuaj hormones no ces xa ib lub cim mus rau lwm lub qog me me hauv lub hlwb hu ua pituitary gland. Lub qog pituitary ces tso tawm lwm hom tshuaj hormones hu ua gonadotropins. Cov gonadotropins no mus ncaj qha rau tus menyuam cov qog sib deev, hu ua gonads. Hauv cov tub hluas, cov no yog "testicles." Cov no tsim cov tshuaj hormones "testosterone." Hauv cov ntxhais, cov no yog "ovaries." Cov no tsim cov tshuaj hormones "estrogen."

Feem ntau, ib tug ntxhais pib laus zuj zus thaum muaj hnub nyoog 8 txog 13 xyoos. Ib tug tub pib laus zuj zus thaum muaj hnub nyoog 9 txog 14 xyoos . Txawm li cas los xij, hauv qhov no, "Precocious Puberty", cov txheej txheem no pib ntxov dua. Uas yog, ib tug ntxhais pib qhia cov cim no ua ntej hnub nyoog 8 xyoos, thiab ib tug tub pib qhia cov cim no ua ntej hnub nyoog 9 xyoos .

Puas muaj cov hom tseem ceeb ntawm kev laus ua ntej yug?

Yog, muaj ob hom tseem ceeb. Cia peb saib seb lawv yog dab tsi.

1. Kev Loj Hlob Thaum Yau

Qhov no yog hom mob uas feem ntau tshwm sim . Qhov uas tshwm sim ntawm no yog tias tus menyuam lub hlwb pib tso tawm cov tshuaj hormones hu ua 'Gonadotropin-releasing hormone (GnRH)' ua ntej lub sijhawm xav tau. Qhov no ua rau cov noob qes thiab zes qe menyuam tso tawm cov tshuaj hormones poj niam txiv neej, xws li 'androgens', ua ntej lub sijhawm.

2. Kev Loj Hlob Ua Ntej Hnub Nyoog

Hom mob no yog tshwm sim los ntawm teeb meem nrog cov menyuam yaus lub cev xeeb tub, xws li cov zes qe menyuam, noob qes, lossis cov qog adrenal. Qee zaum, qhov mob no kuj tuaj yeem tshwm sim los ntawm cov tshuaj hormones nkag mus rau hauv lub cev los ntawm ib puag ncig sab nraud. Qhov no tseem hu ua gonadotropin-independent precocious puberty.

Leej twg raug tus mob no ntau tshaj? Nws tshwm sim ntau npaum li cas?

Tseeb tiag, txhua tus menyuam yaus tuaj yeem muaj qhov teeb meem no thaum tseem hluas. Txawm li cas los xij, nws feem ntau tshwm sim rau cov ntxhais dua li cov tub hluas.

Hais txog qhov muaj feem ntau, tus mob no cuam tshuam txog li 20 ntawm 10,000 tus ntxhais, tab sis tsawg dua 5 ntawm 10,000 tus tub.

Vim li cas tib neeg thiaj li loj hlob sai ua luaj? Yog vim li cas?

Cov laj thawj sib txawv nyob ntawm hom uas tau hais ua ntej.

Cov Ua Rau Mob Nruab Nrab Ua Ntej Laus

Raws li tau hais ua ntej lawm, qhov no yog vim muaj kev tso tawm cov tshuaj hormone "(GnRH)" sai sai los ntawm lub hlwb. Feem ntau, tshwj xeeb tshaj yog rau cov ntxhais, nws nyuaj rau nrhiav qhov ua rau qhov no meej. Txawm li cas los xij, qee zaum tej yam zoo li no tuaj yeem ua rau nws:

• Kev raug mob hlwb
• Cov qog nqaij hlav hauv hlwb
• Kab mob hauv lub hlwb
• Kev ua tsis taus ntawm lub hlwb
• Kev kho mob hluav taws xob

Cov Ua Rau Peripheral Precocious Puberty

Hom kab mob no yog tshwm sim los ntawm teeb meem nrog cov kab mob ntawm tus menyuam lub cev xeeb tub lossis cov qog adrenal. Piv txwv li:

• Cov qog nqaij hlav ntawm lub zes qe menyuam, noob qes lossis qog adrenal
• Cov qog nqaij hlav uas tsim cov tshuaj hormones hu ua "Human Chorionic Gonadotropin (HCG)"
• Qee yam mob caj ces, piv txwv li, McCune-Albright syndrome.
• Kev mob hypothyroidism hnyav heev
• Cov kab mob ntawm cov qog adrenal, piv txwv li, "Congenital adrenal hyperplasia"

Qee zaum, kev raug cov tshuaj hormones los ntawm sab nraud lub cev ntawm tus menyuam kuj tuaj yeem yog ib qho ua rau muaj teeb meem no. Xav txog tej yam xws li tshuaj pleev, tshuaj, lossis cov tshuaj ntxiv uas muaj estrogen lossis testosterone, lossis androgens.

Cov cim qhia tias koj lub cev laus ua ntej lub sijhawm yog dab tsi? Koj paub li cas?

Cov tsos mob uas pom tau rau cov txiv neej thiab cov poj niam suav nrog pob txuv, ntxhiab tsw ntawm lub cev ntau ntxiv, thiab nce siab sai sai . Tsis tas li ntawd, cov yam ntxwv ntawm kev sib deev kuj pib tshwm sim ua ntej.

Xav txog seb, koj tus ntxhais xya xyoo mam li pom nws lub mis loj hlob tuaj, lossis koj tus tub yim xyoo lub suab hloov pauv thiab nws pib muaj hwj txwv loj hlob. Cov no yog cov yam uas peb hu ua cov cim qhia.

Cov tsos mob pom hauv cov ntxhais:

• Kev loj hlob ntawm lub mis
• Pib muaj hli
• Cov plaub hau loj hlob hauv qhov chaw mos thiab thaj chaw ntiag tug

Cov tsos mob pom hauv cov tub hluas:

• Lub suab nrov nrov
• Cov plaub hau loj hlob ntawm lub ntsej muag, qhov chaw mos, thiab thaj chaw ntiag tug
• Kev loj hlob ntawm tus qau thiab noob qes
• Kev loj hlob ntawm cov leeg nqaij

Leej twg muaj feem yuav mob no ntau dua?

Muaj ib txhia pawg neeg uas muaj feem yuav loj hlob sai dua me ntsis. Lawv yog:

• Cov ntxhais
• Cov menyuam yaus uas rog dhau los yog rog dhau
• Cov menyuam yaus ntawm qee pawg neeg (Kev tshawb fawb tau qhia tias qhov no feem ntau tshwm sim ntawm cov menyuam dub hauv cov tebchaws txawv teb chaws. Qhov no yuav tsum tau kawm ntxiv hauv peb lub tebchaws.)

Cov teeb meem dab tsi uas tuaj yeem tshwm sim vim yog lub hnub nyoog hluas ntxov?

Txawm hais tias ib tug me nyuam sai sai nce siab thaum lawv mus txog lub hnub nyoog laus zuj zus, kev loj hlob yuav nres thaum lub sij hawm tiav ntawm lub hnub nyoog laus. Yog li ntawd, lawv yuav luv dua li lwm tus me nyuam uas muaj hnub nyoog zoo sib xws. Qhov no tuaj yeem cuam tshuam rau tus me nyuam lub siab.

Ib qho ntxiv yog tias cov menyuam yaus yuav txaj muag thiab tsis xis nyob thaum lawv lub cev hloov pauv sai dua li lwm tus menyuam. Xav txog seb nws yuav nyuaj npaum li cas rau ib tug menyuam yaus pom lawv lub cev hloov pauv loj thaum lawv cov phooj ywg hauv chav kawm tseem yog menyuam yaus xwb.

Cov teeb meem no tuaj yeem ua rau cov menyuam yaus muaj teeb meem kev coj cwj pwm, kev xav, thiab kev sib raug zoo. Lawv yuav muaj kev ntxhov siab thiab kev nyuaj siab. Lawv kuj tseem yuav muaj kev pheej hmoo ntau dua ntawm kev siv tshuaj yeeb thiab ua tus cwj pwm txaus ntshai.

Cov kws kho mob kuaj mob li cas?

Thaum koj coj koj tus menyuam mus ntsib kws kho mob, nws yuav xub kuaj xyuas tus menyuam kom zoo zoo. Nws kuj tseem yuav nug koj txog keeb kwm mob nkeeg ntawm koj tus menyuam thiab seb puas muaj leej twg hauv koj tsev neeg tau muaj mob zoo li no.

Tom qab ntawd nws muaj peev xwm ua cov kev ntsuam xyuas zoo li no:

• X-ray ntawm tes thiab dab teg: Qhov no kuaj xyuas tus menyuam lub hnub nyoog pob txha. Yog tias lub cev tsim cov tshuaj hormones poj niam txiv neej ntau dhau, cov pob txha yuav loj hlob sai dua li qub. Qhov no yog ib qho cim ntawm kev laus ua ntej.
• Kev kuaj ntshav: Qhov no kuaj xyuas cov tshuaj hormones ntawm tus menyuam. Tshwj xeeb, nws kuaj xyuas cov tshuaj hormones "Luteinizing Hormone (LH)" thiab "Follicle-Stimulating Hormone (FSH), uas yog tsim los ntawm lub qog pituitary. Cov no yog cov tshuaj hormones uas tswj kev laus. Nws kuj kuaj xyuas cov tshuaj hormones poj niam txiv neej.
• Kev ntsuas MRI ntawm lub hlwb: Qhov kev kuaj no pab tshem tawm cov teeb meem xws li qog hauv hlwb.
• Kev kuaj ultrasound ntawm lub plab mog: Qhov kev kuaj no tuaj yeem ua tau yog tias koj xav tias koj tus menyuam muaj lub cev hluas ua ntej lub sijhawm. Qhov kev kuaj no kuaj xyuas seb puas muaj qog hauv lub zes qe menyuam lossis cov qog adrenal hauv cov ntxhais, vim tias qee zaum cov no tuaj yeem ua rau lub cev hluas ua ntej lub sijhawm.

Nyob ntawm cov txiaj ntsig ntawm cov kev kuaj no, koj tus kws kho mob yuav xa koj mus rau tus kws kho mob endocrinologist rau menyuam yaus, tus kws kho mob uas tshwj xeeb hauv cov kab mob ntsig txog cov tshuaj hormones rau menyuam yaus.

Cov kev kho mob rau qhov no yog dab tsi?

Cov kev kho mob nyob ntawm seb hom kev laus ua ntej yug los yog thaum twg.

Kev Kho Mob Rau Central Precocious Puberty

Lub hom phiaj tseem ceeb ntawm hom tshuaj no yog kom tiv thaiv kev tsim cov tshuaj hormones 'LH' thiab 'FSH' los ntawm lub qog pituitary. Qhov no ua rau cov cim ntawm kev laus qeeb thiab tuaj yeem ncua kev coj khaub ncaws. Qhov no feem ntau ua tiav nrog cov tshuaj hu ua 'GnRH agonist'. Qhov no kuj hu ua 'Puberty Blocker'. Qhov no yog cov tshuaj hormones tsim los ntawm txiv neej. Qhov no yog ua kom tiv thaiv kev tsim cov tshuaj hormones yug me nyuam lossis cov tshuaj hormones loj hlob. Tus kws kho mob yuav muab cov tshuaj no rau tus menyuam ua koob tshuaj ntawm lub sijhawm tshwj xeeb. Kev kho mob no yuav tsum tau txuas ntxiv mus txog thaum lub sijhawm zoo rau kev laus pib.

Kev Kho Mob Rau Peripheral Precocious Puberty

Hom mob no kho tau los ntawm kev tshem tawm qhov chaw uas muaj cov tshuaj hormones poj niam txiv neej. Tej zaum ib txhia menyuam yuav xav tau phais kom tshem tawm cov qog lossis lwm yam pob uas ua rau lawv loj hlob sai. Lwm tus yuav xav tau cov tshuaj steroid, xws li glucocorticoids. Qee zaum, tus mob no tuaj yeem tswj tau los ntawm kev tshem tawm qhov chaw uas muaj cov tshuaj hormones sab nraud, xws li cov tshuaj pleev estrogen.

Puas tiv thaiv tau kom tsis txhob muaj hnub nyoog laus zuj zus?

Qhov mob no feem ntau nyuaj rau tiv thaiv. Txawm li cas los xij, nws tuaj yeem tiv thaiv tau qee yam los ntawm kev txwv tsis pub tus menyuam raug cov tshuaj hormones poj niam txiv neej los ntawm cov chaw sab nraud. Piv txwv li, nws yog ib qho tseem ceeb kom khaws cov tshuaj pleev, tshuaj pleev, lossis lwm yam tshuaj uas muaj estrogen lossis testosterone kom deb ntawm cov menyuam.

Yav tom ntej yuav zoo li cas rau cov menyuam yaus uas muaj tus mob no?

Yav tom ntej ntawm ib tug me nyuam nyob ntawm ntau yam:

• Lub hnub nyoog pob txha
• Tus menyuam lub hnub nyoog thaum cov tsos mob pib tshwm sim
• Qhov xwm txheej no tau tshwm sim sai npaum li cas
• Txoj kev npaj kho mob rau tus menyuam

Tiamsis tsis muaj dab tsi yuav tsum ntshai. Yog tias kuaj pom thaum ntxov thiab kho nrog tshuaj lossis, yog tias tsim nyog, phais, qhov mob feem ntau tuaj yeem tswj tau. Tom qab ntawd tus menyuam tuaj yeem loj hlob raws li qhov nrawm ib txwm thiab mus txog hnub nyoog laus.

Thaum twg kuv yuav tsum nrog kws kho mob tham txog qhov no?

Yog tias koj tus menyuam muaj tej yam cim qhia tias nws yuav laus ua ntej lub sijhawm, tshwj xeeb tshaj yog tias tus menyuam hnub nyoog qis dua 8 xyoos (yog tias yog ntxhais) lossis 9 xyoos (yog tias yog tub), mus ntsib kws kho mob tam sim ntawd.

Kuv yuav tsum nug tus kws kho mob li cas?

Koj tuaj yeem nug cov lus nug zoo li no:

• Puas yog kuv tus menyuam yeej tab tom loj hlob sai sai?
• Vim li cas qhov no thiaj tshwm sim rau kuv tus menyuam?
• Koj xav kom kuv tus menyuam kho li cas?
• Puas yog kuv tus menyuam xav tau tshuaj los tswj tus mob no?
• Puas muaj cov pab pawg txhawb nqa uas pab cov menyuam yaus uas loj hlob sai?
• Peb puas yuav tsum mus ntsib kws kho mob endocrinologist rau menyuam yaus?

Vim li cas cov ntxhais zoo li dhau lub hnub nyoog laus dua li niaj hnub no?

Hauv cov teb chaws zoo li Tebchaws Meskas, lawv hais tias muaj cov ntxhais hluas pib laus sai dua. Ib qho laj thawj rau qhov no yog vim muaj kev rog ntau ntxiv hauv cov teb chaws ntawd. Raws li cov kws tshawb fawb, muaj kev sib txuas ntawm kev muaj lub cev loj (BMI) thiab kev loj hlob ntawm lub mis thaum ntxov. Kuj tseem muaj kev ntseeg tias kev noj zaub mov ua tiav ntau dhau, cov zaub mov muaj roj ntau kuj tuaj yeem ua rau lawv laus sai dua.

Tsis tas li ntawd xwb, haiv neeg kuj tau hais tias muaj feem cuam tshuam rau qhov no. Piv txwv li, cov ntxhais dub thiab Hispanic hauv Tebchaws Meskas tau tshaj tawm tias lawv yuav mus txog hnub nyoog laus dua li lwm haiv neeg. Vim tias kev rog dhau ntau dua ntawm cov pab pawg no, qhov ntawd kuj tseem yuav yog ib qho laj thawj rau qhov kev nce ntxiv ntawm hnub nyoog laus thaum ntxov.

Txawm li cas los xij, cov no feem ntau yog kev tshawb fawb ua nyob rau hauv txawv teb chaws. Qhov xwm txheej hauv peb lub teb chaws yuav txawv. Yog li ntawd , yog tias koj muaj kev tsis ntseeg txog koj tus menyuam, qhov zoo tshaj plaws ua yog nrhiav kev pab tswv yim los ntawm kws kho mob.

Yog li ntawd, tej yam tseem ceeb tshaj plaws uas peb yuav tsum nco ntsoov los ntawm zaj dab neeg no yog dab tsi?

Lub sijhawm uas koj tseem hluas thiab hluas tuaj yeem ua rau koj tus menyuam thiab niam txiv nyuaj siab me ntsis. Tiam sis nws yog ib qho tseem ceeb uas yuav tsum paub txog qhov no.

• Yog koj pom cov cim qhia tias koj lub cev yuav laus ua ntej hnub nyoog 8 xyoo (ua ntej hnub nyoog 8 xyoo rau cov ntxhais thiab ua ntej hnub nyoog 9 xyoo rau cov tub), tsis txhob xav tias qhov no yooj yim. Mus ntsib kws kho mob tam sim ntawd.
• Muaj ntau yam ua rau qhov no. Tej zaum yuav tsis pom qhov ua rau pom tseeb. Txawm li cas los xij, kev kuaj mob tuaj yeem pab nrhiav tau.
• Muaj cov kev kho mob zoo. Yog tias kuaj pom thaum ntxov thiab kho tau, tus menyuam txoj kev loj hlob yuav zoo li qub.
• Nco ntsoov txog koj tus menyuam txoj kev noj qab haus huv ntawm lub hlwb thiab. Tej zaum lawv yuav pom tias nws nyuaj rau lawv lees txais qhov kev hloov pauv no. Muab kev hlub thiab kev txhawb nqa rau lawv. Xa lawv mus rau kev pab tswv yim yog tias tsim nyog.

Qhov tseem ceeb tshaj plaws yog kom paub tias koj tsis nyob ib leeg. Cov kws kho mob yeej npaj txhij pab koj thiab koj tus menyuam. Yog li ntawd, tsis txhob ntshai, thiab nrhiav kev pab kho mob thaum koj tsis paub meej.

Kev Laus Ua Ntej, cov tshuaj hormones, kev loj hlob ntawm menyuam yaus, kev laus ua ntej, ntxhais, tub