Cia peb kawm txog Radiopharmaceuticals hauv txoj kev yooj yim. Qhov no yuav tseem ceeb heev rau koj!

Tej zaum koj yuav ntshai me ntsis thaum koj hnov ​​lo lus "radiopharmaceuticals," puas yog? Lo lus "radioactive" tam sim ntawd ua rau koj xav txog qee yam txaus ntshai, tab sis thaum siv kom raug hauv kev kho mob, lawv tuaj yeem pab tau zoo heev. Yog li hnub no, cia peb tham txog lawv yog dab tsi, lawv ua haujlwm li cas, thiab lawv muaj kev nyab xeeb npaum li cas rau koj.

Cov tshuaj radiopharmaceuticals no yog dab tsi? Cia peb nkag siab yooj yim!

Hais yooj yim xwb, cov '(Radiopharmaceuticals)' no kuj yog ib hom tshuaj tshwj xeeb . Tab sis lawv muaj ib qho me me ntawm cov khoom siv radioactive, uas yog, lawv yog radioactive. Tsis txhob txhawj, qhov no yog kev tswj hwm, kev nyab xeeb ntawm radioactivity. Peb cov kws kho mob, uas yog, cov kws kho mob thiab cov neeg muab kev pab kho mob cuam tshuam, siv cov tshuaj no rau kev kuaj duab hauv kev kho mob nuclear thiab los kho qee yam kab mob, tshwj xeeb tshaj yog cov qog nqaij hlav .

Xav txog nws, thaum lawv xav pom seb puas muaj qee yam tsis ncaj ncees lawm hauv koj lub cev, qee zaum cov kws kho mob muab me ntsis tshuaj rau koj haus lossis txhaj tshuaj ua ntej luam theej duab? Qhov no yog ib yam dab tsi zoo li ntawd. Cov tshuaj tshwj xeeb no yog ua thiab muab los ntawm cov neeg tau kawm tshwj xeeb hu ua cov kws muag tshuaj nuclear . Tom qab ntawd , cov kws kho mob hluav taws xob thiab cov kws kho mob hluav taws xob (RTs) siv lawv los ua cov kev kuaj mob. Qee zaum, cov kws kho mob hluav taws xob kuj muab cov tshuaj no ua kev kho mob.

Cov tshuaj radiopharmaceuticals no siv rau dab tsi?

Cov tshuaj no feem ntau siv ua ob ntu. Cia peb saib seb lawv yog dab tsi.

1. Tshuaj Kho Mob Hluav Taws Xob

Cov tshuaj Radiopharmaceuticals feem ntau siv rau hauv kev kuaj duab tshuaj nuclear . Peb hu cov no ua "kev kuaj mob radiopharmaceuticals." Tsuas yog nyob hauv Tebchaws Meskas xwb, kwv yees tias muaj ntau lab qhov kev kuaj tshuaj nuclear no tau ua txhua xyoo. Yog li koj tuaj yeem xav txog seb lawv siv dav npaum li cas.

Cov kev kuaj no tuaj yeem xyuas seb cov kab mob thiab cov nqaij hauv koj lub cev puas ua haujlwm zoo . Qhov no ua li no:

Koj yuav tau muab cov tshuaj radioactive no me me rau koj haus, nqus pa, lossis txhaj tshuaj. Cov no qee zaum hu ua cov tshuaj radiotracers . Cov tshuaj radioactive uas koj tau txais yuav tsis ua rau koj raug mob. Nws yog ib qho me me xwb. Cov tshuaj no mus rau thaj chaw uas muaj teeb meem hauv koj lub cev thiab sau. Tom qab ntawd, lub koob yees duab rhiab heev, xws li lub koob yees duab gamma, ntes tau cov tshuaj radiation hauv koj lub cev thiab tsim cov duab uas tus kws kho mob pom tau.

Xav txog seb, cov tshuaj no zoo li ib tug kws tshawb nrhiav uas mus rau hauv lub cev, nrhiav cov teeb meem thiab qhia peb tias, "Qhov no yog qhov teeb meem."

Nov yog qee qhov piv txwv ntawm kev siv cov tshuaj radiopharmaceuticals rau kev kuaj mob:

• Fluorine-18: Qhov no yog ib qho radiotracer feem ntau siv rau hauv PET scans (Positron Emission Tomography scans).
• Technetium 99m: Qhov no yog cov khoom siv radioactive feem ntau siv hauv kev kho mob nuclear. Nws yog siv los kuaj xyuas cov pob txha, kev ua haujlwm ntawm daim siab, thiab kev ua haujlwm ntawm lub raum.
• Xenon-133: Qhov no yog tshuaj radioactive uas koj nqus tau. Nws yog muab los xyuas kev ua haujlwm ntawm lub ntsws (kev kuaj xyuas kev ua haujlwm ntawm lub ntsws).
• Rubidium-82: Qhov no yog ib yam tshuaj uas muab rau koj los ntawm cov hlab ntsha hauv lub plawv (IV). Nws yog siv los saib xyuas qhov mob ntawm cov leeg nqaij plawv (myocardial imaging).

2. Cov Tshuaj Radiopharmaceutical Kho Mob

Tam sim no cia peb tham txog seb cov tshuaj no siv li cas rau kev kho mob. Cov no txawv me ntsis ntawm cov uas siv rau kev kuaj mob. Cov tshuaj Radiopharmaceuticals siv rau kev kho mob tso tawm cov hluav taws xob muaj zog heev thiab tua cov cell . Qhov no yog ua los tua cov cell tsis zoo, tshwj xeeb tshaj yog cov cell mob qog noj ntshav .

Cov tshuaj no zoo li "cov neeg yos hav zoov." Uas yog, lawv nrhiav pom cov hlwb qog noj ntshav thiab xa kev kho mob hluav taws xob ncaj qha mus rau cov hlwb ntawd . Qhov no txawv ntawm kev kho mob hluav taws xob sab nraud , uas siv lub tshuab los xa cov hluav taws xob los ntawm sab nraud koj lub cev. Tab sis cov tshuaj kho mob hluav taws xob no ua haujlwm ncaj qha los ntawm kev tsom mus rau lub hom phiaj.

Qhov kev siv cov tshuaj radioactive rau kev kho mob no, yog qhov tshiab heev. Cov kws tshawb fawb tseem tab tom tshawb nrhiav kev siv tshiab rau lawv. Lawv ntseeg tias cov tshuaj radiopharmaceuticals kho mob yuav ua lub luag haujlwm tseem ceeb heev hauv kev kho mob qog noj ntshav yav tom ntej.

Cov tshuaj radiopharmaceuticals siv los kho mob qog noj ntshav yog dab tsi?

Muaj ntau hom "Radiopharmaceuticals" uas cov kws kho mob siv los kho mob qog noj ntshav. Piv txwv li:

• PLUVICTO® (lutetium Lu 177 vipivotide tetraxetan): Qhov no yog ib yam tshuaj uas tau txais kev pom zoo los ntawm US Food and Drug Administration (FDA). Nws yog siv los kho mob qog nqaij hlav prostate (PSMA-positive metastatic castration-resistant prostate cancer - PSMA-positive mCRPC).
• Lutathera™ (Lutathera™ - Lutetium Lu 177 dotatate)`:Qhov no kuj yog ib yam tshuaj uas FDA pom zoo. Nws yog siv los kho qee yam qog nqaij hlav neuroendocrine (somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors) uas tshwm sim hauv plab, hnyuv, thiab pancreas.
• Iodine-131: Qhov no yog hom kev kho mob tseem ceeb ntawm kev siv iodine radioactive. Nws tuaj yeem kho qee yam mob qog noj ntshav hauv thyroid thiab qee kis ntawm Graves' kab mob, tseem hu ua hyperthyroidism.
• Radium-223: Qhov no zoo heev rau kev kho cov qog pob txha uas tshwm sim thaum mob qog nqaij hlav prostate kis mus rau cov pob txha. Lub Koom Haum FDA hauv Tebchaws Meskas tau pom zoo Radium-223 dichloride (Xofigo™) rau lub hom phiaj no.

Tsis tas li ntawd xwb, ntau lwm hom kev kho mob radiopharmaceutical tam sim no nyob rau hauv kev sim tshuaj rau lwm hom mob qog noj ntshav.

Cov tshuaj radiopharmaceuticals uas siv ntau tshaj plaws yog dab tsi?

Raws li peb tau hais ua ntej lawm, Technetium-99m yog ib yam tshuaj siv hluav taws xob uas cov kws kho mob siv feem ntau. Nws feem ntau yog siv rau kev kuaj mob duab. Nws pab "pom" cov hauv qab no:

• Kev tso ntshav tawm hauv koj lub ntsws (kev ntws ntshav) hauv koj lub ntsws.
• Kev ntws ntshav hauv koj lub cev hlab ntsha (Kev ntws ntshav hauv cov hlab ntsha).
• Cov pob txha.
• Cov ntaub so ntswg Myocardial.
• Cov qog kua muag.
• Cov qog thyroid.

Qee lwm cov tshuaj radiopharmaceuticals uas siv ntau yog:

• ¹⁸F Fluorodeoxyglucose `(¹⁸F Fluorodeoxyglucose - FDG)`
• Gallium-68 DOTATATE
• Gallium-68 PSMA `(Gallium-68 PSMA)`
• ¹⁸F PSMA `(¹⁸F PSMA)`
• Iodine 123 `(Iodine 123)`

Yog li cov tshuaj radiopharmaceuticals no puas muaj kev nyab xeeb tiag?

Qhov no yog ib lo lus nug uas ntau tus neeg muaj. Thaum siv thiab tswj kom zoo, cov tshuaj radiopharmaceuticals muaj kev nyab xeeb. Koj tus kws kho mob radiologist thiab/lossis kws kho mob radiation oncologist yuav ua haujlwm nrog tus kws muag tshuaj nuclear kom paub tseeb tias qhov ntau npaum li cas ntawm cov tshuaj radiopharmaceutical uas koj tau txais yog qhov tseeb thiab muaj kev nyab xeeb . Yog li tsis muaj dab tsi yuav txhawj txog.

Ib yam li txhua yam tshuaj, kev kho mob hluav taws xob tuaj yeem ua rau muaj qee qhov kev mob tshwm sim . Txawm li cas los xij, cov txiaj ntsig ntawm cov tshuaj feem ntau ntau dua li cov kev pheej hmoo. Koj tus kws kho mob yuav piav qhia cov kev mob tshwm sim no rau koj ua ntej koj pib kho mob.

Txawm hais tias cov tshuaj radiopharmaceuticals tau siv rau ntau xyoo hauv kev siv tshuaj nuclear imaging, lawv nyuam qhuav pib siv los kho mob qog noj ntshav. Cov kws tshawb fawb tseem tab tom kawm txog seb cov tshuaj radioactive no tsom thiab tua cov hlwb qog noj ntshav li cas. Yog tias koj xav paub txog kev sim tshuaj ntawm cov tshuaj radiopharmaceuticals rau kev kho mob qog noj ntshav, tham nrog koj tus kws kho mob. Lawv zoo siab pab koj.

Thaum kawg, tej yam tseem ceeb tshaj plaws uas koj yuav tsum nco ntsoov

Zoo, yog li, los ntawm qhov peb tau tham txog, cov no yog cov yam tseem ceeb uas koj yuav tsum nco ntsoov:

• Cov tshuaj Radiopharmaceuticals yog ib hom tshuaj tshwj xeeb uas tswj tau cov radioactivity .
• Cov no feem ntau yog siv rau kev kuaj mob (piv txwv li PET scans, pob txha scans) thiab kho qee yam kab mob, tshwj xeeb yog mob qog noj ntshav .
• Hauv kev kuaj mob, cov no ua haujlwm ua "radiotracers", "taw qhia" cov cheeb tsam ntawm lub cev uas muaj teeb meem.
• Hauv kev kho mob, cov no pab tsom thiab rhuav tshem cov hlwb qog noj ntshav .
• Cov tshuaj no muaj kev nyab xeeb thaum muab rau hauv kev saib xyuas kho mob kom zoo . Ib yam li txhua yam tshuaj, tej zaum yuav muaj cov kev mob tshwm sim me me, tab sis feem ntau cov txiaj ntsig ntau dua li lawv.
• Qhov kev lag luam no, tshwj xeeb tshaj yog hauv kev kho mob qog noj ntshav, tseem tab tom hloov zuj zus , thiab yuav muaj ntau yam kev txhim kho ntxiv yav tom ntej.

Yog li, lub sijhawm tom ntej koj hnov ​​​​txog "(Radiopharmaceutical)", koj tam sim no muaj kev nkag siab zoo dua txog nws yog dab tsi thiab nws siv rau dab tsi, puas yog? Yog tias koj muaj lus nug ntxiv, tsis txhob yig nug koj tus kws kho mob.

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