Koj lub thyroid puas zoo li ua haujlwm ntau dhau lawm? Cia peb tham txog Subclinical Hyperthyroidism!

Koj tus kws kho mob puas tau hais tias koj qib TSH qis me ntsis hauv kev kuaj ntshav tsis ntev los no? Los yog koj puas muaj qee yam tsos mob txawv txawv, nyuaj rau nkag siab? Tej zaum koj muaj ib qho mob hu ua Subclinical Hyperthyroidism. Tsis txhob txhawj, feem ntau nws tsis loj heev. Cia peb tham txog qhov no yooj yim thiab meej.

Subclinical hyperthyroidism yog dab tsi?

Hais yooj yim xwb, 'Subclinical Hyperthyroidism' yog ib qho mob uas koj lub qog thyroid ua haujlwm ntau dua li qub me ntsis. Tab sis nws tsis hnyav npaum li 'overt hyperthyroidism' .

Lub qog pituitary hauv peb lub hlwb tsim cov tshuaj hormones hu ua 'TSH' (Thyroid-Stimulating Hormone). Qhov 'TSH' no qhia rau lub qog thyroid hauv peb lub caj dab kom tsim ob hom tshuaj hormones hu ua thyroxine ('T4' - 'thyroxine') thiab triiodothyronine ('T3' - 'triiodothyronine'). Cov tshuaj hormones 'T3' thiab 'T4' no yog cov uas pab peb lub cev ua haujlwm metabolism, uas yog, hloov cov khoom noj uas peb noj mus ua lub zog thiab siv nws rau peb lub cev.

Hauv 'Subclinical Hyperthyroidism', koj cov ntshav 'TSH' qib qis, tab sis koj cov 'T3' ​​thiab 'T4' qib yog qhov qub. Qhov ntawd txhais tau tias lub thyroid yog me ntsis overactive, yog li lub qog pituitary hais tias, "Okay, kuv tsis xav tau 'TSH' tam sim no, kuv lub thyroid ua haujlwm zoo," thiab nws txo qhov tsim tawm ntawm 'TSH'. Tab sis cov tshuaj hormones thyroid ('T3', 'T4') tseem tsis tau nce siab heev. Qhov ntawd yog qhov 'subclinical' txhais tau tias - ib qho mob hauv qab uas tsis qhia cov tsos mob pom tseeb.

Qhov mob no qee zaum yuav yog ib ntus xwb , uas txhais tau tias nws yuav zoo dua nws tus kheej hauv ob peb hnub. Txawm li cas los xij, rau qee tus neeg nws yuav zoo mus tas li. Tsis yog txhua tus neeg xav tau kev kho mob.

Leej twg yuav muaj feem yuav mob no tshaj?

Txhua tus neeg tuaj yeem muaj tus kab mob 'Subclinical Hyperthyroidism', tab sis cov neeg hauv qab no muaj feem yuav mob ntau dua me ntsis:

• Cov neeg uas tab tom noj tshuaj thyroid hormone replacement therapy (piv txwv li, levothyroxine) rau hypothyroidism. Qee zaum qhov no tuaj yeem tshwm sim yog tias qhov koob tshuaj ntawm cov tshuaj raug nce me ntsis.
• Rau cov neeg hnub nyoog tshaj 65 xyoo.

Tus mob no feem ntau tshwm sim li cas?

Qhov no tsis yog ib qho xwm txheej uas tshwm sim ntau heev hauv cov tebchaws zoo li Asmeskas.

Kwv yees li ntawm 0.7% ntawm cov pej xeem muaj 'Subclinical Hyperthyroidism', qhov twg TSH theem tsawg dua 0.1 mIU/L. Lwm 1.8% muaj 'TSH' theem tsawg dua 0.4 mIU/L.

Txawm li cas los xij, hauv cov tebchaws uas muaj qhov tsis txaus iodine , tshwj xeeb tshaj yog cov neeg hnub nyoog tshaj 70 xyoo, qhov mob no tuaj yeem siab txog 15%. Hauv Sri Lanka, peb feem ntau siv ntsev iodized , yog li qhov kev pheej hmoo no tsawg, tab sis nws yog qhov zoo kom paub.

Cov tsos mob yog dab tsi?

Feem ntau, cov neeg uas muaj 'Subclinical Hyperthyroidism' tsis muaj tsos mob dab tsi li . Yog vim li ntawd nws thiaj hu ua "subclinical".

Txawm li cas los xij, qee zaum koj yuav muaj cov tsos mob me me ntsig txog hyperthyroidism. Thaum lub sijhawm zoo li no, koj yuav muaj tej yam xws li:

• Zoo li koj lub plawv dhia ceev (palpitations).
• Zoo li kuv lub cev tshee hnyo, tsuas yog xav tias ntshai xwb.
• Poob phaus (txawm tias muaj kev ntshaw).
• Kev ntshaw zaub mov ntau ntxiv.
• Raws plab los yog tso zis ntau zaus.
• Daim tawv nqaij zoo li nyias, sov, thiab noo.
• Kev hloov pauv ntawm cov poj niam lub voj voog muaj hli (`Kev hloov pauv ntawm lub hli`).

Tseem Ceeb: Muaj cov tsos mob no tsis tau txhais hais tias koj muaj 'Subclinical Hyperthyroidism'. Txawm li cas los xij, yog tias cov tsos mob no tseem muaj, nws yog ib qho zoo uas yuav tsum mus ntsib kws kho mob.

Vim li cas qhov no thiaj tshwm sim? Yog vim li cas?

Feem ntau, peb lub endocrine system ua haujlwm zoo li ib pab neeg. Xav txog nws zoo li ib lub tuam txhab loj.

Lub hypothalamus, nyob rau hauv qab ntawm lub hlwb, tso tawm ib hom tshuaj hormones hu ua TRH (Thyroid-Releasing Hormone). Qhov no qhia rau lub qog pituitary kom tsim TSH.

Ces `TSH` mus thiab qhia rau lub qog thyroid kom ua `T3` ​​​​(kwv yees li 20%) thiab `T4` (kwv yees li 80%). Thaum cov `T3` ​​​​thiab `T4` no nce ntxiv hauv cov ntshav, nws rov xa ib lub teeb liab mus rau lub qog pituitary hais tias, "Okay, tsum tsis txhob ua `TSH` tam sim no, muaj cov tshuaj hormones txaus." Qhov no hu ua ` feedback loop` . Thaum `T3` ​​​​thiab `T4` txo qis, lub voj voog no pib dua los ntawm qhov pib.

Txawm li cas los xij, hauv 'Subclinical Hyperthyroidism', vim muaj qee qhov teeb meem hauv lub qog thyroid, txawm tias 'TSH' qib qis, kev tsim cov tshuaj hormones thyroid tsis txo qis raws li qhov xav tau. Yog vim li cas 'TSH' qis, tab sis 'T3' ​​thiab 'T4' nyob rau theem ib txwm.

Cov ua rau muaj "Subclinical Hyperthyroidism" feem ntau zoo ib yam li cov uas ua rau muaj hyperthyroidism. Nov yog qee qhov ua rau tseem ceeb:

• Nce qhov koob tshuaj ntawm kev kho mob hormone (levothyroxine) rau hypothyroidism (tsis ua haujlwm ntawm thyroid). Qhov no yog qhov ua rau feem ntau tshwm sim.
• Kab mob qog ntshav ntau lub qog. Qhov no yog ib qho mob uas cov qog uas tsis yog mob qog noj ntshav (nodules) tshwm sim hauv cov qog thyroid, ua rau nws tsim cov tshuaj hormones thyroid ntau dhau.
• Kab mob Graves. Qhov no yog ib yam kab mob uas tiv thaiv kab mob tsis pub nws rov qab ua haujlwm li qub. Qhov no txhais tau tias peb lub cev tiv thaiv kab mob tawm tsam lub qog thyroid, ua rau nws tsim cov tshuaj hormones ntau ntxiv.
• Mob Thyroiditis: Thaum cov qog thyroid o, cov tshuaj hormones yuav nce ntxiv ib ntus.

Koj paub qhov no li cas?

Kev kuaj mob thyroid yog tib txoj kev los paub tseeb tias koj puas muaj 'Subclinical Hyperthyroidism' lossis tsis muaj.(Kev kuaj mob thyroid xwb. Cov no yog kev kuaj ntshav ib txwm muaj.

Tus nqi ib txwm rau TSH (tseem hu ua thyrotropin) hauv tus neeg laus uas tsis cev xeeb tub yog ntawm 0.4 thiab 4.5 milli-international units per liter (mIU/L).

Yog tias koj cov kev kuaj ntshav qhia tias koj cov TSH qib qis (nruab nrab ntawm 0.1 thiab 0.4 mIU/L lossis tsawg dua 0.1 mIU/L), tab sis koj cov T4 (thyroxine) thiab T3 (triiodothyronine) nyob hauv qhov ntau thiab tsawg, koj muaj Subclinical Hyperthyroidism.

'Subclinical Hyperthyroidism' muaj ob pawg tseem ceeb:

• Me ntsis xwb: TSH qib qis, tab sis tseem pom tau - feem ntau ntawm 0.1 thiab 0.4 mIU/L. Qib no muaj nyob rau hauv 65% txog 75% ntawm cov neeg uas muaj Subclinical Hyperthyroidism.
• Hnyav: TSH qib tsawg dua 0.1 mIU/L. Qhov no cuam tshuam rau ntawm 25% thiab 35% ntawm cov neeg.

Qhov no puas xav tau kev kho mob?

Muaj cov kev xav sib txawv ntawm cov kws kho mob txog seb puas yuav kho 'Subclinical Hyperthyroidism', vim tias tseem tsis tau muaj kev tshawb fawb txaus txog cov txiaj ntsig ntawm kev kho mob.

Cov kws kho mob feem ntau pom zoo kom cov neeg uas muaj tus mob hyperthyroidism uas tsis pom tseeb ua ntej yuav siv txoj kev "tos thiab saib" (subclinical hyperthyroidism). Yog li ntawd, lawv tos kom tus mob zoo dua yam tsis tau pib kho.

Txawm li cas los xij, kev kho mob yuav raug pom zoo rau cov neeg uas TSH theem qis dua 0.1 mIU / L, tshwj xeeb tshaj yog nyob rau hauv cov xwm txheej hauv qab no:

• Yog koj muaj hnub nyoog 65 xyoo lossis laus dua.
• Yog koj hnub nyoog qis dua 65 xyoos, muaj kab mob plawv, osteoporosis, lossis cov tsos mob ntawm hyperthyroidism.
• Yog tias koj yog ib tug poj niam postmenopausal, hnub nyoog qis dua 65 xyoos, thiab tsis noj tshuaj estrogen lossis bisphosphonates (ib hom tshuaj siv los kho cov teeb meem pob txha).

Feem ntau, subclinical hyperthyroidism thaum cev xeeb tub tsis tas yuav kho.

Yog tias muaj kev kho mob, nws yog dab tsi?

Yog koj tus kws kho mob txiav txim siab tias kev kho mob yog qhov tsim nyog, kev kho mob yuav nyob ntawm qhov ua rau muaj subclinical hyperthyroidism.

• Yog tias koj muaj ib qho mob goiter uas muaj ntau lub qog (ib lub qog hauv caj dab) lossis ib lub qog ntawm koj lub thyroid, kev kho mob feem ntau yog radioactive iodine . Qhov no yog ib yam tshuaj uas koj noj los ntawm qhov ncauj. Cov qe ntshav uas ua haujlwm ntau dhau hauv koj lub thyroid nqus cov iodine. Cov radioactive iodine ua rau cov qe ntshav ntawd puas tsuaj, ua rau lub thyroid me me thiab koj cov tshuaj hormones poob qis hauv ob peb lub lis piam.
• Yog koj muaj tus kab mob Graves, cov kev kho mob feem ntau yog cov tshuaj antithyroid thiab cov tshuaj radioactive iodine. Cov tshuaj antithyroid xws li methimazole (Tapazole) thiab propylthiouracil (PTU) ua haujlwm los ntawm kev thaiv lub qog thyroid txoj kev tsim cov tshuaj hormones.

Qhov no puas tiv thaiv tau kom tsis txhob tshwm sim?

Feem ntau, peb tsis muaj dab tsi ua tau los tiv thaiv qhov teeb meem "Subclinical Hyperthyroidism" lossis "Hyperthyroidism" uas pom tseeb.

Txawm li cas los xij, yog tias koj tsis tau txais iodine txaus hauv koj cov zaub mov (lossis ntau dhau) , koj tuaj yeem tsim 'Subclinical' lossis 'Oert Hyperthyroidism' vim yog 'toxic goiter'. Txawm hais tias qhov no tsis tshua muaj nyob rau hauv cov tebchaws zoo li Sri Lanka vim peb siv ntsev iodized, qhov mob no tuaj yeem pom hauv cov tebchaws uas muaj iodine deficiency ntau.

Peb yuav xav li cas txog qhov teeb meem no? Puas muaj tej yam txaus ntshai?

Cov mob hyperthyroidism uas tsis pom tseeb feem ntau yuav hloov mus ua hyperthyroidism uas pom tseeb. Txawm li cas los xij, qhov kev pheej hmoo no siab dua me ntsis rau cov neeg uas muaj TSH qis heev (tsawg dua 0.1 mIU/L).

Vim muaj ntau yam ua rau, txhua tus neeg tus mob 'Subclinical Hyperthyroidism' txawv.

Txawm tias nws tsis nce mus rau 'Overt Hyperthyroidism' los xij, 'Subclinical Hyperthyroidism' tuaj yeem ua rau muaj qee yam teeb meem. Ib txhia ntawm lawv yog:

• Atrial fibrillation ( lub plawv dhia tsis sib xws).
• Kev ua tsis tau lub plawv (kev pheej hmoo ntawm kev ua tsis tau lub plawv ).
• Kab mob plawv (kab mob plawv coronary ).
• Pob txha poob thiab pob txha tawg.
• Dementia ( ib qho mob uas ua rau lub cim xeeb tsis zoo uas tshwm sim thaum muaj hnub nyoog).

Cov kev pheej hmoo no tshwj xeeb tshaj yog rau cov neeg hnub nyoog tshaj 65 xyoos thiab cov neeg uas muaj mob hyperthyroidism subclinical hnyav.

Yog tias koj txhawj xeeb txog cov kev pheej hmoo no, nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob txog qhov no.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Feem ntau, yog tias koj cov kev kuaj mob qhia tias koj muaj "Subclinical Hyperthyroidism," cov kws kho mob yuav siv txoj hauv kev "tos thiab saib".

Txawm li cas los xij, yog tias koj pib muaj cov tsos mob ntawm hyperthyroidism (ntxhov siab, tsis nyob twj ywm, lub plawv dhia ceev), nco ntsoov mus ntsib koj tus kws kho mob. Tom qab ntawd nws yuav ua lwm qhov kev kuaj ntshav thyroid kom pom tias koj puas muaj 'Overt Hyperthyroidism'.

Nco ntsoov tias, tseem muaj ntau lub tswv yim sib txawv txog seb puas yuav kho lossis tsis kho 'Subclinical Hyperthyroidism'. Txhua tus neeg, txhua qhov xwm txheej txawv. Yog li ntawd, qhov zoo tshaj plaws uas yuav tsum ua yog tham txog tag nrho koj cov lus nug thiab kev ntshai nrog koj tus kws kho mob. Nws npaj txhij thiab txaus siab los pab koj.

Cov Lus Qhia Txog Kev Coj Mus Tsev

Zoo, ntawm no yog qee yam uas koj yuav tsum nco ntsoov los ntawm qhov peb tau tham txog:

• "Subclinical Hyperthyroidism" yog ib qho mob uas cov thyroid caj pas ua haujlwm ntau dhau me ntsis xwb, tab sis tsis muaj tsos mob loj.
• Qhov no raug kuaj pom los ntawm kev kuaj ntshav uas qhia tias TSH qis (tab sis T3 thiab T4 ib txwm muaj).
• Vim tias feem ntau tsis muaj tsos mob, tej zaum yuav tsis tas yuav kho mob. Koj tus kws kho mob yuav siv txoj hauv kev "tos thiab saib".
• Tej tus neeg, tshwj xeeb yog cov neeg laus lossis cov neeg uas muaj teeb meem kev noj qab haus huv, yuav xav tau kev kho mob.
• Yog tias koj muaj cov tsos mob ntawm hyperthyroidism (xws li lub plawv dhia ceev, tshee hnyo, poob phaus), mus ntsib kws kho mob tam sim ntawd.
• Qhov tseem ceeb tshaj plaws yog tsis txhob ntshai, tham qhib siab txog qhov no nrog koj tus kws kho mob, thiab ua raws li nws cov lus qhia.

Vam tias koj pom cov ntaub ntawv no muaj txiaj ntsig. Nyob kom noj qab nyob zoo!

Kev mob thyroid ntau dhau , TSH, T3, T4, cov tshuaj hormones, kab mob Graves, goiter