Wetin na AA Amyloidosis? Lɛ wi lan bɔt am jɔs!

Yu dɔn ɛva wɔnda wetin go apin if sɔm prɔtin dɛn na wi bɔdi go smɔl smɔl? Tide wi go tɔk bɔt wan pan dɛn kayn tin ya we nɔ kin apin so ɔltɛm, bɔt we impɔtant fɔ mek wi no bɔt. Dɛn kɔl am AA Amyloidosis.

Wetin na AA Amyloidosis? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, AA Amyloidosis na wan kayn big grup fɔ sik dɛn we dɛn kɔl amyloidosis. Naw yu go de aks se, ‘Wetin na dis amyloidosis?’ Wɛl, wi bɔdi gɛt wan kayn prɔtin we dɛn kɔl amyloid. dis protin dεm gεt spεsifi k tri-dimenshכnal shep (3D strכkchכ). Na so dɛn de wok. כltu, sכmtεm dεn protin dεm ya kin chenj dεn shep, tכn lεk bכl fכ tכd, εn fכm sכm sכm fayv dεm (fibril). Dis na wetin wi kin kɔl ‘amiloid dipɔsit’. di akyumyuleshכn fכ dεn dεposit dεm ya na wi difrεn כgan dεm εn tisu dεm dεn kכl am amyloidosis.

insay AA amyloidosis, di lεvεl fכ di sεrum A protin na di bכdi de inkrεs bכku bכku wan bikoz fכ inflameshn pasmak na wi bכdi. If yu gɛt lɔng tɛm infɛkshɔn ɔ inflammatory disease, dis sɛrum A protin lɛvɛl kin go ɔp. in wan we, AA amyloidosis na siriכs komplikashכn fכ dεn inflammatory sik dεm ya. Dɔktɔ dɛn kin trit am bay we dɛn kin trit di sik we de ɔnda di inflammatory disease.

Aw AA amyloidosis de afɛkt wi bɔdi?

Naw lɛ wi si aw dis AA amyloidosis de afɛkt wi bɔdi. I kin pwɛl wi kidni dɛn pas ɔlman . Nɔto dat nɔmɔ, bɔt i kin pwɛl di liva, di splin, di bɛlɛ, ɛn di intestinal dɛn bak. I nɔ kin rili afɛkt di at. Wan ɔda tin na dat dis sik kin afɛkt di prɔtin we de na yu urine ɛn di kɔlɔstrel lɛvɛl na yu blɔd.

Dis na sik we de kil pɔsin?

Yɛs, dis na rili siriɔs prɔblɛm. If dɛn nɔ trit AA Amyloidosis fayn, i kin kil pɔsin . Mɛmba se a bin se dis kin kam bikɔs ɔf wan sik we kin mek pɔsin in bɔdi wam fɔ lɔng tɛm. So, we dɔktɔ dɛn de trit di sik we de ɔnda am, dɛn kin trit di AA amyloidosis bak. So natin nɔ de fɔ wɔri bɔt, bɔt di tin we impɔtant pas ɔl na fɔ no am kwik ɛn gɛt tritmɛnt .

Udat kin gɛt AA amyloidosis mɔ?

If yu tink bɔt udat kin gɛt dis, ɛnibɔdi we gɛt wan sik we nɔ de mɛn kin gɛt AA amyloidosis . Dat min se, if yu gɛt dis kayn sik, i fayn fɔ mek yu no smɔl bɔt dis bak.

Wetin kin mek pɔsin gɛt AA amyloidosis?

Lɛ wi tek tɛm luk gud wan bɔt wetin kin mek dis apin. AA amyloidosis na wan kayn amyloidosis. dכkta dεn kכl dis amyloidosis ``protein misfolding disorder.'' Tink bכt, wi protin dεm na lכng mכlikul dεm we gεt spεshal tri-dimenshכnal (3D) shep dεm. dis protin dεm de du bכku wok na wi bכdi – frכm fכ gi enεji, to bεlε fכ di wata, to fכ εp wit imyuniti, fכ gi di bכdi strכkchכ, fכ muv tin dεm rawnd, to kכntrol di bכdi prכsεs dεm, εn כda tin dεm.

Nɔmal wan, dɛn kin pul dɛn prɔtin ya na di blɔd we dɛn dɔn du dɛn wok. כltu, insay dizכrd we dεn protin dεm ya de fold kכrekt, di protin dεm de chenj shep εn tek abnכmal shep dεm we di bכdi nכ kin yuz כ pul. insay AA amyloidosis, dεn abnכmal protin dεm ya de kכlכm tכgeda εn fכm 'amyloid dεposit', כ `fibrils', insay wi כgan dεm.

stכdi dεm we dεn jכs du dεn dכn sho plεnti kכndyushכn dεm we kin mek AA amyloidosis. Dɛn tin ya na sɔm kayn blɔd kansa, baktriyal infɛkshɔn lɛk ɔlsa we nɔ de dɔn, rεumatik sik lεk rεumatoid at, ɔ inflammatory bowel disease lεk Crohn’s disease ɔ ulcerative colitis. Sɔntɛnde, i kin kam bak bikɔs ɔf tin dɛn we pɔsin kin gɛt frɔm in mama ɛn papa lɛk fiva we kin kam ɔltɛm lɛk famili Mɛditarenian fiva.

Wetin na di sayn dɛm fɔ AA amyloidosis?

Okay, naw lɛ wi si wetin na di sayn dɛm fɔ AA amyloidosis. Bɔku tɛm, i kin afɛkt di kidni dɛn. I kin afɛkt di ɔgan dɛn bak lɛk di liva, di splin, ɛn di bɛlɛ. Si if yu gɛt ɛni wan pan dɛn sayn ya:

• Swel na di leg ɔ ankles . Dis kin bi sayn fɔ se yu gɛt prɔblɛm wit yu kidni. I kin bi sayn bak fɔ sik na di kidni we nɔ de dɔn.
• Urin we gɛt fom ɔ we gɛt frɔt.
• Les urine output pas aw i kin bi.
• Dayarɛa we nɔ de dɔn.
• Di kidni we de big.
• Di liva we de mek i big.
• Lɔw blɔd prɛshɔn.
• Nɔs ɛn vɔmit.

Aw dɔktɔ dɛn kin no se yu gɛt AA amyloidosis?

Aw dɔktɔ dɛn kin no bɔt dis sik? Dɛn kin du sɔm tɛst dɛn. Di men wan na bayɔpsi.

• ``Fat pad'' bayopsi : dis involv fכ tek sכm fεt frכm כnda di skin na di bכdi εn egzamin am. I rili simpul.
• כgan bayopsi : dεn tek sכm sכm tisu sεmpl frכm wan כgan we dεn tink se i afekt εn dεn egzamin am.

pan tap dat, dεn kin du כda tεst dεm fכ kכnfכm if yu gεt כda kayn amyloidosis we dεn kכl ``AL amyloidosis.'' Bikɔs di simptom dεm fכ כl tu di AL amyloidosis εn AA amyloidosis rili fiba, AL amyloidosis na wan tכp we sכmtεm siriכs εn we de go bifo kwik kwik wan .

Aw dɛn kin trit AA amyloidosis?

Naw lɛ wi si wetin na di tritmɛnt dɛn fɔ dis. AA amyloidosis de kכz fכ wan lכng tεm inflammatory kכndishכn we de mek abnכmal protin dεm de bכlכp na yu כgan dεm. So, dɔktɔ dɛn kin trit am bay we dɛn de trit di ɔndalayn inflammatory condition . We yu trit di ɔndalayn kɔndishɔn ɛn ridyus di inflamɛns, di AA amyloidosis kɔndishɔn bak kin gɛt kɔntrol. As di inflameshn lεvεl de dכn, di simptom dεm de dכn sכmtεm.

Dεn gεt dεm bak we de naw fכ trit AA amyloidosis. Dɔktɔ ɛn pipul dɛn we de du risach de kɔntinyu fɔ fɛn nyu tritmɛnt dɛn. fכ egzampl, dεn de invεstigat we dεn fכ pul dεn amyloid fibril dεm ya na di bכdi bifo dεn kin bכlכp insay כgan dεm, εn dεn de invεstigat bak di antibodi dεm we dεn mek na lab we kin tכk εn pul di amyloid fibril dεm we dεn כlrεdi bil insay כgan dεm.

Yu tink se dɛn kin mek dɛn nɔ gɛt AA amyloidosis?

Yu tink se dɛn go ebul fɔ stɔp dis? Infakt, if yu gɛt wan sik we nɔ de mɛn lɛk rεumatoid at, i kin mek sɔm prɔtin dɛn na di blɔd go ɔp ɛn mek yu gɛt AA amyloidosis. So, di wangren we fɔ mek dis nɔ apin na fɔ gɛt tritmɛnt kwik ɛn fayn fɔ di ɔndalayn krɛse sik we yu gɛt .

Yu tink se dɛn kin mɛn AA amyloidosis?

Yɛs, i kin mɛn. Dɔktɔ dɛn kin trit AA amyloidosis bay we dɛn kin trit di ɔndalayn inflammatory kɔndishɔn we mek i apin. Lɛk bɔku sik dɛn, di bɛst we fɔ mɛn AA amyloidosis na fɔ no di sik ɛn bigin fɔ trit am kwik kwik wan .

Aw a kin kia fɔ misɛf?

If yu gɛt AA amyloidosis, di bɛst we fɔ tek kia ɔf yusɛf na fɔ wok wit yu dɔktɔ fɔ trit di ɔndalayn inflammatory kɔndishɔn we mek i gɛt am fayn fayn wan. Risach pipul dεn dכn fכnshכn nכmba כf sik dεm εn kכndyushכn dεm we de mek yu inflameshn fכ lכng tεm we gεt lεk fכ AA amyloidosis. Aks yu dɔktɔ aw yu sik bin mek yu gɛt AA amyloidosis ɛn aw dɛn de trit da inflammatory kɔndishɔn de.

Fɔ tɔk am simpul wan, AA amyloidosis na wan kɔmplikeshɔn we nɔ kin apin so ɔltɛm, bɔt we siriɔs, we kin mek bɔku kɔmɔn inflammatory sik ɔ kɔndishɔn dɛn. Bɔt gud tin na dat, dɔktɔ dɛn kin trit am bay we dɛn de trit di sik we de ɔnda am. Bɔrku tɛm, di sayn dɛm fɔ AA amyloidosis kin tan lɛk di ɔspitul prɔblɛm dɛm wae yu dɔn yus to wit yu inflammatory disease. Bɔt, lɛk ɔda siriɔs sik dɛn, dɔktɔ dɛn kin trit am if dɛn kech am kwik.If yu notis ɛni chenj ɔ nyu sayn fɔ yu at, tɛl yu dɔktɔ wantɛm wantɛm . Dɛn go chɛk yu sayn dɛm ɛn ɛksplen wetin dɛn min.

So, wetin na di impɔtant tin dɛn we wi nid fɔ mɛmba frɔm dis stori?

AA Amyloidosis na wɔd we de mek pɔsin fred smɔl, bɔt i rili impɔtant fɔ ɔndastand am fayn fayn wan.

Mɛmba se dis kin apin bɔrku tɛm as kɔmplikeshɔn fɔ ɔda sik wae de mek pɔrsin gɛt lɔng tɛm inflammatory disease.

• If yu gɛt wan sik we de mek yu bɔdi wam, lɛk at at sik, i rili impɔtant fɔ go to di rayt tritmɛnt .
• If yu gɛt nyu tin dɛn lɛk we yu gɛt prɔblɛm wit yu kidni (we yu de swel na yu leg, yu de chenj yu urine), yu de gɛt dayarɛa ɔltɛm, ɔ yu liva ɔ yu splin big, tɛl yu dɔktɔ .
• if dεn no εn trit AA amyloidosis kwik, dεn kin gεt gud autkam . Di men tin fɔ trit na fɔ trit di ɔndalayn inflammatory disease.
• Nɔ fred, bɔt tek tɛm . Tɔk opin wan wit yu dɔktɔ, tɛl dɛn yu prɔblɛm dɛn. Dɛn go ɛp yu.

So, wi op se dis infɔmeshɔn bin yusful to yu. Stay wit wɛlbɔdi!

` Amyloidosis, AA amyloidosis, protin, inflameshn, kidni sik, krεse sik, rεumatoid atraytis