Yu kin de tek mɛrɛsin fɔ alɛji, asma, fɔ pis ɔltɛm, ɔ fɔ muv sik. Pan ɔl we di mɛrɛsin fɔ ɛni sik difrɛn, bɔku pan dɛn mɛrɛsin ya de pan di sem big klas fɔ drɔgs. Na di klas of drugs we wi go tok abaut tide. Dɛn kɔl dɛn anticholinergics. Sɔntɛm yu nɔ bin dɔn yɛri bɔt dis nem, bɔt sɔntɛm yu dɔn ɔlrɛdi de tek wan pan dɛn kayn drɔgs ya.
Fɔ tɔk am simpul wan, wetin na dɛn anticholinergic drɔgs ya?
Fɔ ɔndastand dis, lɛ wi fɔs tɔk bɔt smɔl tin bɔt wi bɔdi in nervɔs sistɛm. Di nɛv sɛl dɛn na wi bɔdi kin chenj mɛsej to dɛnsɛf, lɛk pɔsin we de post pɔsin we de sɛn lɛta dɛn. wi kכl di kεmikכl dεm we de kכri dεn mεsej dεm ya nyurotransmitta. Wan pan dɛn spɛshal mɛsenja dɛn de na asɛtilkolin .
I de wok mɔ na wan pat pan wi Ɔtonomik Nɛvɔs Sistɛm. Dɛn kɔl am di Parasympathetic Nervous System. Pan ɔl we di nem tan lɛk se i kɔmplikt smɔl, in wok rili simpul. Na wetin de pripia wi bɔdi fɔ "Rɛst ɛn Dayjɛst." Dat min tin dɛn lɛk fɔ mek wi at rit kol, fɔ mek di saliva ɛn di jus we de na di dijestiv, ɛn fɔ kɔntrol di blad wok.
Naw, wetin Anticholinergic drɔgs de du na dat dɛn de ambɔg di wok we da mɛsenja de we dɛn kɔl Acetylcholine de du. Dat min se, dɛn kin blok am. afta dat sכm pan di prכsεs dεm we de εp yu "rεst εn daygεst" de rεdכks sכmtεm. Dis kin rili yusful fɔ wi pan sɔm mɛrɛsin kɔndishɔn dɛn.
Us kayn sik dɛn kin yuz dɛn mɛrɛsin ya fɔ?
I pas 600 drɔgs dɛn we gɛt anticholinergic prɔpati. Dis na di men tin we sɔm drɔgs kin du. I kin bi bak wan sayd ɛfɛkt we ɔda pipul dɛn kin gɛt. Lɛ wi si wetin na di men tin dɛn we dɛn kin yuz dɛn mɛrɛsin ya.
| Nem fɔ di drɔg (ɛgzampul) . | Menly yuz kes dɛm |
|---|---|
| Atropin we gɛt di sik | As tritmɛnt fɔ abnɔmal slo hat rit (bradycardia) ɛn sɔm pɔyzin. |
| Bεnztropin, Trihεksifεnidil | Fɔ kɔntrol di sayn dɛm lɛk fɔ shek shek wae de kam wit Pakinsin sik. |
| Difenhaydramin we dɛn kɔl | I de insay bɔku alɛji pils ɛn sɔm slip pils. |
| Ipratropium, Tiotropium, we dɛn kɔl Tiotropium | I de insay inhala dɛn we dɛn kin yuz fɔ sik dɛn we pɔsin kin gɛt we i de blo lɛk asma ɛn COPD. |
| Oksibutinin, Sɔlifenasin, Tɔltɛrodin | Dɛn kin yuz am bak as krim fɔ kɔntrol di we aw pɔsin kin pis bɔku tɛm (Urge Incontinence) ɛn we di blad mɔsul dɛn kin kɔntrakt. I kin kam bak as krim fɔ trit pɔsin we de swet pasmak (Hyperhidrosis). |
| Skɔpolamin | Dɛn kin gi am fɔ nɔs ɛn vɔmit we kin apin we pɔsin de travul (moshɔn sik). |
| Glykopirolɛt, Vɛkuroniɔm | Dɛn kin yuz am fɔ ridyus di saliva bifo dɛn du ɔpreshɔn ɛn fɔ mek di mɔsul dɛn paralayz we dɛn de du ɔpreshɔn. |
Apat frɔm dat, sɔm mɛrɛsin fɔ pwɛl hat, saykayatrik mɛrɛsin, ɛn sɔm alɛji mɛrɛsin (antihistamines) kin gɛt dis anticholinergic prɔpati bak as sayd ɛfɛkt.
Wetin na di bɛnifit ɛn sayd ɛfɛkt dɛm fɔ dis kayn mɛrɛsin?
Di bɛnifit dɛn we pɔsin kin gɛt
Dɛn drɔgs ya gɛt bɔku yus. Sɔntɛnde, dɛn kin sev layf . Fɔ ɛgzampul, we pɔsin it pɔyzin lɛk insɛktisayd, dɛn kin gi am wan mɛrɛsin we dɛn kɔl Atropine as tritmɛnt. Dis mɛrɛsin kin ɛp bak fɔ mek di at rit bak we i dɔn dɔŋ bad bad wan.
Impɔtant:If pɔsin it pɔyzin, kɛr di pɔsin go wantɛm wantɛm na di ɔspitul Imejɛnsi Tritmɛnt Yunit (ETU) we de nia am. I impɔtant bak fɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ no mɔ.
Bɔt dis mɛrɛsin de ɛp bak fɔ mek wi layf bɛtɛ. Imajin, aw i fayn fɔ mek pɔsin we bin de avɔyd fɔ go trip bikɔs i bin de fred fɔ vɔmit, fɔ ebul tek smɔl pil ɛn go na da trip de we i nɔ gɛt ɛni prɔblɛm? Semweso, dis mɛrɛsin de ɛp pɔsin we bin de fred fɔ go tɔylɛt ɔltɛm, fɔ liv nɔmal layf.
Sayd Ifɛkt dɛn we kin apin
Lɛk ɛni mɛrɛsin, dɛn anticholinergic drɔgs ya kin mek yu gɛt sayd ɛfɛkt. Bɔt nɔto ɔlman kin gɛt dɛn, ɛn dɛn kin difrɛn difrɛn wan bay di doz, di pɔsin in ej, ɛn ɔda sik dɛn we i gɛt. Pipul dɛn we dɔn ol kin gɛt dɛn bad bad tin ya mɔ .
Na dis na smɔl trik fɔ mɛmba dɛn sayd ɛfɛkt ya:
- "Hot as a hare" - di bכdi tεmprachכ de inkrεs.
- "Blaynd as a bat" - di pupil dεm na di yay dεm de dilayt, we de mek di vishכn blכr.
- "Dray as bon" - di prodakshכn fכ saliva εn kray wata de dכn.
- "Rɛd as bit" - Fɔ mek di skin rɛd.
- "Mad as a hatter" - kɔnfyushɔn, mɛmori prɔblɛm.
| Kɔmɔn sayd ɛfɛkt dɛn | Wan simpul ɛksplen |
|---|---|
| Dray Mɔt | Diskɔmfɔt we kin kam bikɔs di saliva nɔ kin bɔku. |
| Vishɔn we Nɔ Gɛt Blɔr | Difikulti fɔ si nia bikɔs di pupil dɔn big. |
| Nɔ ebul fɔ pas urine (Urinary Retention) . | difεlεns fכ ɛmti urine kכmplit wan biכs di blad mכsul dεm de rilaks. |
| Banbɛlɛ | Slowing dכwn fכ di dijestiv prכsεs dεm. |
| Kɔnfyushɔn/Dimɛnshɔn | I kin apin mɔ pan pipul dɛn we dɔn ol. |
| At bit kwik kwik wan (Tachycardia) . | Fɔ fil se yu at de bit mɔ ɛn mɔ. |
Ustɛm a fɔ go to dɔktɔ?
If yu de yuz mɛrɛsin lɛk dis, mek shɔ se yu tɔk to yu dɔktɔ pan dɛn tin ya:
- If di mɛrɛsin we yu de tek nɔ de briŋ di rilif we yu want.
- If i nɔ izi fɔ yu fɔ yuz di mɛrɛsin jɔs lɛk aw di dɔktɔ tɛl yu.
- If di sayd ɛfɛkt dɛm we di mɛrɛsin gɛt de ambɔg yu aktiviti dɛm ɛvride (fɔ ɛgzampul, if yu gɛt prɔblɛm fɔ it bikɔs yu mɔt dray, ɔ if yu gɛt prɔblɛm fɔ drayv ɔ rid buk bikɔs yu nɔ de si fayn fayn wan).
Di tin we impɔtant pas ɔl na dat, nɔ ɛva stɔp fɔ tek ɛni mɛrɛsin ɔ chenj di doz if yu nɔ go to yu dɔktɔ fɔs. If yu du dat, dat kin mek yu sik wɔs.
If yu gɛt ɛni kwɛstyɔn bɔt dɛn mɛrɛsin ya, nɔ fred fɔ aks yu famili dɔktɔ. I kin ɛksplen us tritmɛnt we bɛtɛ fɔ yu, di bɛnifit dɛn we i gɛt, ɛn di bad tin dɛn we i kin du.
Mɛsej we dɛn kin kɛr go na os
- Anticholinergics na wan kɔmɔn klas fɔ mɛrɛsin wae dɛn kin yuse fɔ trit difrɛn kayn sik dɛm, lɛk alɛji, asma, Pakinsin sik, ɛn prɔblɛm wit yu urinary.
- dis dεm de wok bay we dεn de blכk di akshכn we wan kεmikכl mεsenja we dεn kכl asetilkolin de du na di bכdi in nεv sεstem.
- Sɔm bad tin dɛn lɛk we yu mɔt dray, yu nɔ de si fayn, yu kin gɛt bɛlɛ, ɛn yu kin kɔnfyus. Dis risk kin bɔku mɔ pan di wan dɛn we dɔn ol.
- Nɔ ɛva stɔp fɔ tek ɛni mɛrɛsin ɔ chenj di doz if yu nɔ gɛt dɔktɔ advays.
- If yu gɛt ɛnitin fɔ wɔri bɔt yu mɛrɛsin ɔ di bad tin dɛn we i kin du, di bɛst pɔsin fɔ tɔk to na yu dɔktɔ.
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