Aw i nɔ ebul fɔ du natin fɔ fil lɛk se yu nɔ ebul fɔ kɔntrol yu yon bɔdi? Imajin, we yu de tɔk, it, ɔ tray fɔ sayn wan dɔkyumɛnt, yu fes, yu an ɛn fut, ɔ ɔda pat dɛn na yu bɔdi kin bigin fɔ shek ɛn twit we yu nɔ ebul fɔ kɔntrol... Dis na big tin we kin ambɔg yu ɛvride layf ɛn i kin ivin mek yu fred fɔ fes di sosayti. Insay dis atikul, wi go tɔk bɔt wan mɛrɛsin we go ɛp di wan dɛn we de sɔfa wit dɛn kayn muvmɛnt dɛn ya we dɛn nɔ ebul fɔ kɔntrol .
Di tu men mεdikal kכndyushכn dεm wae de mek dεn muvmεnt dεm ya we dεn nכ de kכntro na:
Dɛn kin yuz di drɔg we dɛn kɔl Astedo mɔ fɔ mɛn tu sik dɛn. Lɛ wi tek wan luk pan wetin dɛn bi.
1. Kɔria bikɔs ɔf di sik we dɛn kɔl Huntington: Pan ɔl we dis kin tan lɛk kɔmplikɛt nem, fɔ tɔk am simpul wan, na wan sik we pɔsin kin gɛt frɔm in mama ɛn papa. Insay dis, di nɛv sɛl dɛn na di bren kin pwɛl smɔl smɔl. Dis kin mek wi gɛt prɔblɛm wit aw i de tink, aw i de kɔntrol aw i de fil, ɛn aw i de muv in bɔdi. Wi kin kɔl dis muvmɛnt we pɔsin nɔ ebul fɔ kɔntrol, we kin apin wantɛm wantɛm, we kin twit, we de jɔk, chorea .
. Di men tin we kin mek dis apin na wan sayd ɛfɛkt we di mɛrɛsin dɛn we dɛn kin yuz fɔ sɔm ɔda sik dɛn, mɔ di mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn dɛn maynd, kin gɛt.
Aw Ɔstede de wok na di bɔdi?
Wi bren tan lɛk wan big mɛsej sɛnta. i de sεnd mεsej to di mכsul dεm na di bכdi, lεk "muv" εn "stכp," tru di nεv sεl dεm. di kεmikכl mεsenja dεm we de kכri dεn mεsej dεm ya dεn kכl dεm nyurotransmitta .
Tink bɔt dɛn nyurotransmitta ya lɛk postman. na dεn wan dεm we de kכri lεta (mεsej) frכm di bren to di mכsul dεm.
Dopamin na wan pan dɛn kayn impɔtant mɛsej dɛn de. Insay ɔl tu di kɔndishɔn dɛn we Chorea ɛn Tardive Dyskinesia (TD) we wi bin dɔn tɔk bɔt, dɛn mɛsenja ya we tan lɛk dopamin kin sɛn mɛsej pasmak ɔ di we we nɔ fayn. dis min se di mכsul dεm de gεt tu mכch signal dεm we nכ nid fכ "muv, muv." Na dat mek di bɔdi kin bigin fɔ twit ɛn twit we i nɔ ebul fɔ kɔntrol.
Wetin Austedo de du na fɔ kɔntrol di bɔku mɛsej dɛn we dɛn nɔ nid fɔ sɛn. Dat min se, i de ɛp fɔ ridyus da ‘trafik’ de smɔl ɛn ridyus di muvmɛnt dɛn we nɔ nid.
Aw dɛn fɔ yuz dis mɛrɛsin?
Austedo tablɛt dɛn gɛt tu kayn.
- Pil we yu kin tek ɔltɛm: Yu dɔktɔ kin se yu fɔ tek dis wan ɔ tu tɛm insay di de.
- Austedo XR: Dis na ‘Extended-Release’ pil. Dis min se di mɛrɛsin kin kɔmɔt na di bɔdi fɔ sɔm awa. So, dɛn kin tek am wan tɛm insay di de.
Yu dɔktɔ go stat yu pan wan rili smɔl doz (starting dose) . Dɔn, wik to wik, dɛn go inkrisayz di doz smɔl smɔl te yu fɛn di mentenɛns doz we go ebul fɔ kɔntrol yu sik dɛn fayn fayn wan. So, i rili impɔtant fɔ ajɔst yu doz lɛk aw yu dɔktɔ tɛl yu.
Yu fɔ mɛmba dɛn tin ya we yu de tek mɛrɛsin:
- Austedo rɛgyula tablɛt fɔ tek wit it. Yu kin tek Austedo XR tablɛt wit it ɔ yu nɔ it am.
- Nɔ brok, krɔs, ɔ chew di tablɛt. Swɛla am ɔl wit wan glas wata.
- If yu tek Austedo XR, yu go notis se sɔm pan di tablɛt, lɛk di kɔtin we lɛf, kin pas na yu stɔl afta di mɛrɛsin dɔn absɔb ɔl. Dis na nɔmal tin ɛn i nɔ fɔ mek wi wɔri.
- If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu de tek am ɔltɛm. Nɔ ɛva tek tu dos wan tɛm fɔ mek di wan we yu mis. If yu nɔ shɔ, aks yu dɔktɔ.
Aw yu go no if di mɛrɛsin de wok?
I at fɔ ɛkspɛkt fɔ gɛt rizɔlt wantɛm wantɛm. I kin tek sɔm wik to mɔnt fɔ mek yu muv we yu nɔ ebul fɔ kɔntrol nɔ de muv. I impɔtant fɔ peshɛnt bikɔs yu dɔktɔ go tek sɔm tɛm fɔ fɛn di rayt doz fɔ yu.
If yu fil se yu sik nɔr de bɛtɛ ɔr tan lɛk se yu de wɔs, mek shɔ se yu tɔk to yu dɔktɔ. I kin ebul fɔ chenj di mɛrɛsin we yu de tek ɔ tink bɔt ɔda tritmɛnt.
Sɔm bad bad tin dɛn we kin apin ɛn aw fɔ dil wit dɛn?
Lɛk ɛni mɛrɛsin, Austedo kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Di tebul dɔŋ ya de sho sɔm pan de sayd ɛfɛkt dɛm wae kin mɔna ɛn sɔm simpul we dɛm fɔ mɛn dɛn.
| Sayd Ifɛkt we i kin gɛt | Aw fɔ Manej? |
|---|---|
| Drowsiness, taya | Nɔ du tin dɛn we go mek yu de wach, lɛk fɔ drayv ɔ fɔ yuz mashin, te yu no gud gud wan aw di mɛrɛsin de afɛkt yu. |
| Rɔnbɛlɛ | Fɔ mek yu nɔ gɛt wata na yu bɔdi, drink bɔku wata lɛk wata ɛn jus. It tin dɛn lɛk banana, rays, ɛn bred. If i bad, tɛl yu dɔktɔ. |
| Dray Mɔt | Drink bɔku wata ɔltɛm. Tray fɔ blo tru yu nos instead ɔf yu mɔt. If yu chew gɔm we nɔ gɛt shuga, dat kin ɛp bak. |
| Trobul fɔ Slip | Nɔ drink tin dɛn we gɛt kafinɛ lɛk kɔfi ɛn ti na ivintɛm. Kip wan patikyula tɛm fɔ go slip. Ridyus di yus fɔ yu fon ɛn tablɛt bifo yu go slip. |
| Nos ɔ trot infekshɔn (lɛk kol) . | Bɔku tɛm, dɛn tin ya kin sɔlv insay sɔm dez. If yu drink wam wata ɛn rɛst, dat kin ɛp. If di sayn dɛn de tranga ɔ i nɔ de chenj, tɛl yu dɔktɔ. |
Ɔda mɛrɛsin dɛn we nɔ de wok wit dis mɛrɛsin (Drug Interactions) .
Dis na pat we rili impɔtant . We yu de tek Astedo, mɛrɛsin dɛn de we yu nɔ fɔ tek wit am ɛn we yu fɔ tek tɛm pasmak.
Mɛrɛsin dɛn we yu nɔ fɔ ɛva tek:
- MAOIs (Monoamine Oxidase Inhibitors): Dɛn wan ya na wan kayn mɛrɛsin wae dɛn kin gi fɔ pwɛl hat ɔr sik wae de kam pan pɔrsin.
- Reserpine: Na ol mɛrɛsin we dɛn kin yuz fɔ mek pɔsin gɛt ay blɔd prɛshɔn.
- Tetrabenazine ɛn Valbenazine: Dɛn mɛrɛsin ya na ɔda mɛrɛsin dɛn bak we dɛn kin yuz fɔ mɛn di prɔblɛm dɛn we kin mek pɔsin muv, lɛk Austedo. If yu tek dɛn togɛda, dat kin mek yu gɛt siriɔs sayd ɛfɛkt.
Di mɛrɛsin dɛn we yu fɔ tek tɛm tek:
- CYP2D6 inhibitors: Dis wan na smɔl mɔ kɔmplikɛt. Fɔ tɔk am simpul wan, if yu tek Astedo wit antidipreshan lɛk bupropion ɛn fluoxetine, ɔ at ritm mɛrɛsin lɛk quinidine kin mek di lɛvɛl fɔ Austedo na yu blɔd ɛn i kin mek yu gɛt sayd ɛfɛkt. If yu de tek wan pan dɛn mɛrɛsin ya, yu dɔktɔ kin ridyus yu doz fɔ Austedo.
- Antisaykotik (mɛrɛsin fɔ mɛntɛl sik): We dɛn tek am wit Ɔstedo, dɛn tin ya kin mek yu gɛt bɔku prɔblɛm dɛn lɛk pakinson, mɔsul dɛn we stif (nyurolɛptik malignant sindrom), ɛn we yu nɔ kin rɛst (akathisia).
- Ɔda mɛrɛsin dɛm wae kin mek yu slip ɛn drink rɔm: Austedo kin mek yu slip. So, if yu tek am wit alɛji mɛrɛsin lɛk Benadryl ɔ ɔda mɛrɛsin we de mek yu slip, dat kin mek yu slip mɔ. Nɔ drink rɔm ɔltogɛda we yu de tek Ɔstedo.
So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud di mɛrɛsin dɛn fɔ ɔda sik dɛn, vaytamɛn dɛn, ɛn ivin tradishɔnal mɛrɛsin dɛn).
Mɛsej we dɛn kin kɛr go na os
- Austedo na wan patikyula mɛrɛsin we dɛn kin yuz fɔ trit di muvmɛnt we dɛn nɔ kin kɔntrol we kin kam wit di sik we dɛn kɔl Huntington’s disease ɛn Tardive Dyskinesia (TD).
- Na dɔktɔ in advays nɔmɔ fɔ tek dis mɛrɛsin. Fɔ fala di doz jɔs lɛk aw yu dɔktɔ tɛl yu. Nɔ chenj ɔ stɔp di doz yusɛf.
- Duya, peshɛnt wit di tritmɛnt bikɔs i kin tek sɔm wik ɔ mɔnt fɔ si di rizɔlt.
- I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.
- If bad bad sayd ɛfɛkt apin, di sayn dɛn de wɔs, ɔ yu gɛt ɛni prɔblɛm wit dis mɛrɛsin, tɔk to yu dɔktɔ wantɛm wantɛm.
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