Yu dɔktɔ dɔn gi yu ɔ sɔmbɔdi na yu famili wan mɛrɛsin we dɛn kɔl Belinostat? Bikɔs dis na vaysin we dɛn kin yuz fɔ mɛn kansa, i nɔmal fɔ mek yu fred smɔl ɛn want fɔ no bɔt am. Kansa tritmɛnt na big waka. I rili impɔtant fɔ mek wi no gud gud wan bɔt di mɛrɛsin we wi de tek insay da joyn de. So tide, lɛ wi tɔk simpul ɛn pɔlitiks bɔt dis Belinostat vaysin, di we aw i de wok, di sayd ɛfɛkt dɛn, ɛn tin dɛn we wi nid fɔ tek tɛm bɔt.
Us kayn mɛrɛsin na Belinostat?
Fɔ tɔk am simpul wan, Belinostat na wan kayn kemotɛrapi, ɔ kemikal tritmɛnt we de kil kansa sɛl dɛn. Dɛn kin yuz am mɔ fɔ mɛn wan patikyula kayn kansa we dɛn kɔl peripheral T-cell lymphoma . Pan ɔl we i kɔmplikt smɔl bay in nem, i de tɔk bɔt kansa we de divɛlɔp insay sɛl dɛn we dɛn kɔl T-sɛl dɛn na wi bɔdi in imyun sistɛm.
Bɔt sɔmtɛm dɛn kin yuz dis mɛrɛsin fɔ ɔda kayn kansa lɛk aw yu dɔktɔ dɔn disayd. So if yu nɔ shɔ wetin mek dɛn gi yu dis mɛrɛsin, aks yu dɔktɔ fɔ ɛksplen am to yu.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin tritmɛnt
Bifo yu bigin dis tritmɛnt, i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi prɔblɛm. Ivin sɔntin we yu kin tan lɛk se na smɔl tin kin afɛkt di tritmɛnt. Mek shɔ se yu tɔk mɔ bɔt dɛn tin ya:
- If yu gɛt infekshɔn naw .
- If yu gɛt kidni sik ɔ liva sik .
- If yu gɛt ɛni abnɔmal tin na yu blɔd kɔnt . Dat min se if di ripɔt dɛn we dɛn bin dɔn gɛt trade dɔn sho se di wayt blɔd sɛl dɛn nɔ bɔku, di rɛd blɔd sɛl dɛn nɔ bɔku, ɔ di pletlɛt dɛn nɔ bɔku.
- If yu gɛt alɛji fɔ Belinostat ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ. Dis na impɔtant tin, bikɔs dis mɛrɛsin kin afɛkt yu pikin we nɔ gɛt bɛlɛ.
Aw a go gi yu dis mɛrɛsin?
Dis nɔto mɛrɛsin we yu de swɛla lɛk pil. Dis na infushɔn insay wan vein . Dat min se dɛn kin injɛkt di mɛrɛsin insay yu vein frɔm bɔtul, lɛk salin. Dis prɔses kin tek lɛk af awa so.
Dis tritmɛnt na wɛl bɔdi pɔrsin (dɔktɔ ɔ nɔs) we dɔn gɛt spɛshal trenin pan dis eria kin gi yu na ɔspitul ɔ klinik. So yu nɔ gɛt natin fɔ wɔri bɔt.
Impɔtant:Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin fɔ ɛni rizin. Dɔn bak, nɔ mis di de we yu bin dɔn plan fɔ trit yu. If yu nɔ ebul fɔ atɛnd, duya tɛl yu dɔktɔ ɔ klinik bifo tɛm.
Wetin fɔ du if di mɛrɛsin doz go ɔp?
As dɛn kin gi dis mɛrɛsin na ɔspitul, di chans fɔ mek dɛn tek am pasmak kin rili smɔl. Bɔt if yu tink se yu go dɔn tek ɔvados, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm, ɔ di ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) .
Tin dɛn we yu fɔ mɛmba we yu de du tritmɛnt
We wi de du kemotɛrapi, i kin afɛkt di kansa sɛl dɛn ɛn di wɛlbɔdi sɛl dɛn na wi bɔdi. So pe atɛnshɔn mɔ to dɛn pɔynt dɛn ya.
- Protɛkt yusɛf frɔm infɛkshɔn: Dis mɛrɛsin kin mek yu bɔdi nɔ ebul fɔ fɛt infɛkshɔn . So, if yu gɛt sɔm sayn dɛn lɛk fiva, kol, bɔdi we de at, trot we de at, ɛn kɔf, nɔ fɔ tek mɛrɛsin fɔ yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm. Nɔ mek yu nɔ go na say dɛn we pipul dɛn kin bɔku ɛn say dɛn we sik pipul dɛn de.
- Wach fɔ blɔd: Dis mɛrɛsin kin mek yu gɛt mɔ blɔd ɛn brus. Tɛl yu dɔktɔ if yu gɛt blɔd na yu gam, yu nos de blɔd, ɔ yu gɛt brus we nɔ kɔmɔn.
- Diskɔmfɔt na yu bɔdi: Na nɔmal tin fɔ fil pen ɛn taya we yu de trit yu. Bɔt if yu gɛt ɛni bad bad tin, tɛl yu dɔktɔ. I rili impɔtant fɔ dɔn di tritmɛnt we dɛn dɔn tɛl yu fɔ du, ilɛksɛf i nɔ fayn, te yu dɔktɔ tɛl yu fɔ stɔp.
Dɛn nid fɔ mek pipul dɛn no mɔ bɔt bɛlɛ ɛn fɔ bɔn pikin.
Dis na pat we rili impɔtant .
- Fɔ uman dɛn: Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 6 mɔnt afta yu dɔn stɔp di tritmɛnt. If yu de plan fɔ gɛt bɛlɛ ɔ yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
- Fɔ man: Nɔ fɔ bɔn pikin we yu de tek dis mɛrɛsin ɛn fɔ 3 mɔnt afta yu dɔn stɔp fɔ trit yu. Dis mɛrɛsin kin ambɔg di pikin we nɔ bɔn yet bad bad wan.
- Mama dɛm we de gi pikin in bɛlɛ: Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 2 wik afta di las doz.
- Fɔ bɔn pikin: Dis mɛrɛsin kin afɛkt di we aw yu ebul fɔ bɔn pikin. If yu gɛt ɛnitin fɔ wɔri bɔt dis, tɔk to yu dɔktɔ bifo yu bigin fɔ trit yu ɛn gɛt di advays we yu nid.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Belinostat kin mek yu gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i impɔtant fɔ no bɔt dɛn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di lip, tong, ɛn fes. |
| I nɔ kin izi fɔ yu fɔ blo | Shortness of breath, pen na yu chɛst. |
| Di sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, kɔf, trot we de at, bɔdi we de at. |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | di yay ɔ di skin de yɔlɔ, di urine we de dak yɔlɔ/brawn, di ɔpa rayt bɛlɛ de pen, i nɔ de want fɔ it. |
| Di sayn dɛn we de sho se pɔsin de blɔd | Blɔd na di stɔl ɔ blak, tar stɔl, brawn vɔmit we tan lɛk kɔfi grɔn, rɛd/dak brawn urine, ɛn brus we dɛn nɔ ɛksplen. |
| Ɔda | Diziz, taya pasmak ɔ taya. |
| Tin dɛm fɔ tɛl yu dɔktɔ if dɛn kɔntinyu ɔr de mɔna yu | |
| Prɔblɛm dɛn we de na di dijestiv sistɛm | Blɔt (dayarɛa), nɔs, vɔmit, nɔ want fɔ it. |
Di Intarakshɔn wit Drug
I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek. Sɔm mɛrɛsin kin intarakt wit Belinostat, chenj in ifɛkt ɔr inkrisayz di sayd ɛfɛkt.
Nɔ tek Belinostat wit dɛn mɛrɛsin ya:
- atazanavir we dɛn kɔl atazanavir
Dis mɛrɛsin kin mek yu gɛt sayd ɛfɛkt bak:
- erlotinib we dɛn kɔl erlotinib
- gemfibrozil we dɛn kɔl gemfibrozil
- sorafenib we dɛn kɔl sorafenib
Dis list nɔ kin gɛt ɔl di mɛrɛsin dɛn. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek. Dɔn bak, tɛl yu dɔktɔ if yu de smok ɔ drink rɔm.
Mɛsej we dɛn kin kɛr go na os
- Belinostat na wan injɛkshɔn we dɛn kin put insay di bɛlɛ we dɛn kin yuz fɔ mɛn bɔku kayn kansa.
- Bifo yu bigin fɔ trit yu, tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi istri, di mɛrɛsin dɛn we yu de tek, ɛn di alɛji.
- We yu de du tritmɛnt, pe atɛnshɔn mɔ to fiva, sayn dɛn we de sho se yu gɛt di sik, ɛn blɔd we nɔ kɔmɔn. If yu notis ɛni sayn, tɛl yu dɔktɔ wantɛm wantɛm.
- Nɔ gɛt bɛlɛ ɛn bɔn pikin dɛn we yu de trit am ɛn fɔ sɔm tɛm afta yu dɔn trit yu. Nɔ gi pikin in bɛlɛ bak.
- Tɔk to yu dɔktɔ bɔt ɛni sayd ɛfɛkt we yu gɛt, ilɛksɛf i smɔl. Nɔ ayd ɛnitin.
- I rili impɔtant fɔ fala di dɔktɔ in instrɔkshɔn ɛn fes di tritmɛnt wit kɔrej ɛn pɔsitiv.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Ustɛm dɛn kin gi di Vecuronium / Norcuron vaysin?
Dis nɔto ɔdinari mɛrɛsin! Dis na wan kayn mɛrɛsin we rili pawaful we de mek di pɔsin nɔ ebul fɔ waka we dɔktɔ dɛn kin injɛkt insay wan vein (IV) fɔ ‘numb/paralyze’ ɔl di mɔsul dɛn na di pɔsin in bɔdi fɔ sɔm tɛm (ivin di mɔsul dɛn we de blo) we dɛn de du siriɔs ɛn big ɔpreshɔn ɔ we dɛn kɔnɛkt di pɔsin to atifishal respirashɔn mashin (Ventilator)!
💬 Aw dis injεkshכn (Vecuronium) de paralayz di כl bכdi?
fכ mek wi mכsul dεm muv, wi nid fכ sεnd kεmikכl mεsej we dεn kכl ‘Acetylcholine’ frכm di nεv dεm. as dis injεkshכn go insay di bכdi, i de blכk/klos כl di get dεm (Nicotinic acetylcholine receptors) insay dεn mכsul dεm 100% (Non-depolarizing blocker). Bikɔs no we nɔ de fɔ mek di mɛsej go, di pɔsin nɔ kin ebul fɔ muv/brit ɛnitin we dɛn de du di ɔpreshɔn ɛn in bɔdi kin swɛla ɔl.
💬 Wetin na di bad bad denja dɛm we yu fɔ no bɔt we yu de injekt dis mɛrɛsin (Vecuronium)?
Di big ɛn kil denja na dat dis kin ivin mek di ‘mɔsul we de blo (Diaphragm) paralayz, so afta dis di pɔsin we sik nɔ kin ebul fɔ blo insɛf! Dɛn fɔ rili put tiub tru dɛn mɔt ɛn huk dɛn to ventilator (ɔ dɛn go day insay sɔm minit)! Dɔn bak, ivin afta dɛn dɔn du di ɔpreshɔn, sɔm pipul dɛn kin gɛt rɛsɛdyuɛl paralayz ɛn i nɔ kin izi fɔ dɛn fɔ blo fayn.
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