Yu tink se kansa kin skata to yu bon dɛn? (Bone Metastasis) Lɛ wi tɔk bɔt dis!

Yu go dɔn yɛri bɔt pɔsin we gɛt kansa we leta gɛt pen na in bon ɔ in bon dɛn wik. Sɔntɛm yusɛf go dɔn ɛkspiriɛns dis. Dis kin rili bi bikɔs di kansa sɛl dɛn kin kɔmɔt na wan pat na di bɔdi to di bon dɛn. Wi kin kɔl dis bon mɛtastasis . Pan ɔl we dis na siriɔs sik, nɔ panik. Di tin we impɔtant pas ɔl na fɔ no bɔt am ɛn manej am fayn fayn wan.

Wetin na Bɔn Mɛtastasis? Lɛ wi ɔndastand am simpul wan.

Fɔ tɔk am simpul wan, bon mɛtastasis na we di kansa sɛl dɛn we bigin ɔdasay na yu bɔdi (lɛk di bɔdi, di lɔng, ɔ di prɔstat) de travul tru yu blɔd go na yu bon dɛn ɛn bigin fɔ gro de. Dis na wan pan di sayn dɛm we de sho se pɔsin gɛt kansa we dɔn pas .

Di impɔtant tin fɔ no na dat dis nɔto praymar bon kansa. Dis na kansa we dɔn skata to di bon dɛn frɔm ɔdasay.

Bɔt i sɔri fɔ no se, no mɛrɛsin nɔ de fɔ dis sik. Bɔt bɔku tritmɛnt dɛn de fɔ kɔntrol di sik ɛn slo fɔ mek di sik go bifo. Wan ɔda tin na dat pipul dɛn de liv lɔng wit kansa pas aw dɛn bin de liv bifo, so di bon mɛtastasis de kam bɔku. wan stכdi sho se di insidεns fכ bon mεtastas inkrεs frכm 3% insay di fכs ia afta dεn no se i gεt kεnsar to 8% 10 ia afta dat.

Wetin na di sayn dɛm fɔ dis? Si if yu gɛt dɛn tin ya bak

Di tin we kin apin mɔ na di bon pen . I kin fil lɛk se dɛn de pul sɔntin ɔ i ebi. Di pen kin wɔs na nɛt, mɔ na nɛt. Sɔntɛnde, i kin shap, i kin chuk pɔsin, ɔ i kin shap.

Bɔn mɛtastasis kin mek ɔda prɔblɛm dɛn. Sɔm patikyula sayn dɛn de bak we gɛt fɔ du wit am:

• Bon Frakshכn: Dis kכndyushכn de mek yu bon dεm bכku bכku bכku wan. In ɔda wɔd dɛn, yu kin brok bon we yu nɔ fɔdɔm big big wan. I kin afɛkt ɛni bon na yu bɔdi. Bɔt i kin afɛkt di spayna, di rib, di bɛlɛ, di humerus, di fimur, ɛn di skel. Di pen we pɔsin kin fil we bon brok kin rili shap ɛn i kin rili bad. If yu brok yu an ɔ yu leg, yu nɔ go ebul fɔ muv am.
• Hypercalcemia: Dis na we di kalsiɔm we de na yu blɔd kin tumɔs. Di sayn dɛm na diziz, kɔnstipɛshɔn, nɔr kin want fɔ it, nɔs, ɛn vɔmit.
• Spinal Kɔd Kɔmpreshɔn: If na tumbu we dɔn skata ɛn de prɛs pan yu spaynal kɔd, yu kin gɛt bak pen, yu an ɛn yu fut kin wik ɔ swɛ, ɛn yu nɔ kin ebul fɔ urinary. Dis naDɛn fɔ trit am lɛk se na imejensi.

Wetin mek dis de apin? Wetin na di rizin?

Dis sik kin apin we di sɛl dɛn we kɔmɔt na di kansa tɔŋ dɛn brok, go insay yu blɔd, travul tru am, dɔn travul go na yu bon dɛn. we dεn rich de, dεn kεnsar sεl dεm de bigin wan prכsεs we masta sabi pipul dεm kכl "vicious cycle of bone metastasis."

Fɔ ɔndastand dis saykl, i kin ɛp fɔ no smɔl bɔt aw yu bon sɛl dɛn de wok. Tu men kayn sɛl dɛn de na wi bon dɛn: ɔstioblast ɛn ɔstioklast .

• כstioblast na sεl dεm we de mek nyu bon.
• כstioklast na sεl dεm we de sכlv, brok dכn, εn pul ol bon sεl dεm we dεn dכn pwεl.

nכmal wan, dεn tu kayn sεl dεm ya de wok tכgeda fכ mek bεlε bitwin di prodakshכn fכ nyu bon sεl dεm εn di riplesmεnt fכ ol bon sεl dεm. Bɔt we kansa go insay di bon dɛn, dis prɔses nɔ kin go fayn. Na dis na wetin kin apin:

• If di ɔstioblast dɛn mek tumɔs nyu bon sɛl dɛn, yu bon go bɔku tumɔs, ɛn yu go gɛt say dɛn we di bon dɛn nɔ de mek fayn. Yu dɔktɔ kin kɔl dɛn say ya ɔstiosklerɔtik lɛshɔn ɔ ɔstiɔblastik lɛshɔn . Dɛn say dɛn ya kin luk tranga wan we yu luk am na do, bɔt dɛn kin rili brok, lɛk ays we tan lɛk tin we tan lɛk ays we de nia riva. Dɛn kin brok ɛn krɔs izi wan.
• we di osteoklast dεm de brok di bon sεl dεm fast fast pas aw i nכmal, di tin dεm we yu bon sεl dεm de kכmכt kin mek sכm sכm ol dεm na yu bon. If yu luk am wit maykroskɔp, i kin tan lɛk se pɔsin dɔn drɔ ol dɛn na yu bon. Yu dɔktɔ kɔl dɛn ol ya ɔsteolytic lesions . Dɛn lɛsin ya kin mek yu bon dɛn kin brok ɛn wik. Dis kin mek yu gɛt mɔ chans fɔ brok bon.

Risach dɔn sho se sɔntin gɛt sɔntin fɔ du wit sɔm kayn bon sɛl dɛn ɛn sɔm kayn kansa we de pas ɔlsay. fכ egzampl, 70% to 85% pan di bon mεtastas dεm frכm prכstat kεnsar na כsteogenic, we min se na כsteoblast dεm we de mek tu mכch bon de kכz am. כltu, 75% pan di mεtastas dεm frכm brεst kεnsar na כsteolytic, we min se na di bon sεl dεm we de brok dכn tu kwik.

Aw yu no dis?

Yu dɔktɔ go du sɔm difrɛn imej tɛst fɔ no dis sik. Dɛn kin du blɔd tɛst ɔ urine tɛst bak fɔ luk fɔ tin dɛn we de sho se dɛn bon dɔn pwɛl. Di tɛst dɛn we dɛn kin du fɔ tek pikchɔ kin inklud:

• Bon skan
• CT skan (Kɔmpyut tomografi - CT skan) .
• MRI skan (Magnetik rεsכnans imej - MRI skan)
• PET skan (Positron emission tomografi - PET skan) .
• X-ray we dɛn kin du

Dɛn tɛst ya kin tɛl yu di rayt tin we de apin to yu bon dɛn, if di kansa sɛl dɛn dɔn skata, ɛn aw fa dɛn dɔn skata.

Wetin na di tritmɛnt dɛn?

Bɔt i sɔri fɔ no se, no mɛrɛsin nɔ de fɔ di bon mɛtastasis. Bɔt sɔm mɛrɛsin ɛn tritmɛnt dɛn de we kin ɛp fɔ ridyus di pen ɛn kɔntrol aw di sik de go bifo . Dɛn tritmɛnt ya kin ɛp yu fɔ mek yu layf bɛtɛ.

Na sɔm pan di men we dɛn fɔ trit am:

• Bisphosphonates: Dɛn drɔgs ya (e.g., Pamidronate, Zoledronic acid (Zometa®)) de mek yu bon dɛn strɔng, ridyus di amount of kalsiɔm na yu blɔd, ɛn ridyus di risk fɔ gɛt hypercalcemia.
• Kimotɛrapi ɔ ɔmon tɛrapi: Yu dɔktɔ kin gi yu dis tritmɛnt if yu gɛt pas wan say we kansa sɛl dɛn de skata (mɛtastas) to yu bon dɛn.
• Monoclonal antibody therapy: Dɛn kin gi drɔgs lɛk Denosumab (Prolia® ɔ Xgeva®) fɔ ridyus di risk fɔ mek di bon brok.
• Redyushɔn tɛrapi: If yu gɛt pen frɔm wan tumbu na wan pan yu bon dɛm, dɛn kin gi yu redyushɔn tɛrapi fɔ trit da pen de. I kin ɛp bak fɔ di pen we pɔsin kin gɛt we i de kɔmprɛs di spaynal kɔd. Yu dɔktɔ kin gi yu kɔtikosterɔyd bak wit redyushɔn tɛrapi.
• Kyphoplasty: Dis na tritmɛnt fɔ spɛshal kɔmpreshɔn fraktrɔs.
• Ɔpreshɔn: Yu dɔktɔ kin se yu fɔ du ɔpreshɔn fɔ mek yu bon dɛn we nɔ gɛt bɛtɛ trɛnk ɔ fɔ pul wan tumbu we gɛt kansa.

Mɛmba se yu dɔktɔ go disayd di bɛst tritmɛnt fɔ yu, so tɔk to am bɔt dis fayn fayn wan.

Wetin kin apin if dɛn nɔ trit am?

If dɛn nɔ trit di bon mɛtastasis, kɔmplikeshɔn dɛn lɛk aypa kalsiɔm kin apin. If dɛn nɔ trit dis, dis kin mek i go na kɔma. Dɔn bak, yu nɔ go ebul fɔ waka ɔ du yu wok bikɔs yu bon dɛn dɔn brok. If yu bon pen bad bad wan, dat kin mek yu nɔ ebul fɔ ɛnjɔy layf. di mכst imכtant, di kכmpreshכn na di spεnal kכd kin mek i paralayz if dεn nכ trit am. So, nɔ ignore di sayn dɛm.

Wetin fɔ ɛkspɛkt if yu gɛt bon mɛtastasis?

If yu gɛt bon mɛtastasis, dat min se kansa frɔm ɔda pat na yu bɔdi dɔn skata to yu bon dɛm. Dis na sayn fɔ se kansa dɔn go bifo . If na so i bi, yu go nid mɛrɛsin ɛn sɔpɔt fɔ ɔl tu di praymari kansa ɛn di bon mɛtastasis.

I rili impɔtant fɔ mek yu nɔ fred, fala di advays we dɔktɔ de gi yu, ɛn kɔntinyu fɔ gɛt gud maynd.

Aw lɔŋ yu kin liv wit dis sik?

I at fɔ gi wan ansa to dis kwɛstyɔn. Na bikɔs i dipen pan bɔku tin dɛn. Dis tɛm kin difrɛn, bɔku tɛm i kin de frɔm siks mɔnt to pas 4 ia. Di men tin dɛn we kin afɛkt am na:

• Di kayn kansa: Wan stɔdi sho se di tɛm we pɔsin kin liv we i gɛt kansa na in lɔng we dɔn pas na di bon dɛn na lɛk siks to sɛvin mɔnt, bɔt fɔ prɔstat kansa we dɔn skata to di bon dɛn, di tɛm we i kin liv kin bi lɛk 53 mɔnt.
• Stej fɔ kansa: Pipul dɛn we gɛt kansa we dɛn no na stej I (Stej I) nɔ kin gɛt bon mɛtastas pas di wan dɛn we dɛn no na stej IV (Stej IV). Fɔ ɛgzampul, di wan dɛn we de du risach we bin trak di rit we di bon mɛtastas dɛn kin gɛt 10 ia afta dɛn dɔn no se dɛn gɛt kansa, bin si se 3% pan di pipul dɛn we gɛt stej I kin gɛt di sik, we 28% pan di pipul dɛn we gɛt stej IV kin gɛt am.

A bin gɛt stej 1 kansa, we bin de na rɛmishɔn. Wetin mek mi kansa bin skata?

I sɔri fɔ no se sɔntɛnde ivin afta dɛn dɔn trit kansa ɛn i dɔn de na remission , mɛtastas kansa, we dɛn kin kɔl bak bon mɛtastasis, kin kam. ``Rɛmishɔn'' min se yu nɔ gɛt ɛni sayn fɔ gɛt kansa ɛn yu nɔ go ebul fɔ fɛn ɛni sayn fɔ kansa pan tɛst. If yu gɛt bon mɛtastas, yu dɔktɔ kin kɔl dis sik bak distant recurrent cancer . Kansa we kin kam bak na we kansa kin kam bak afta dɛn dɔn trit am.

Aw a kin kia fɔ misɛf?

Bɔn mɛtastasis kin afɛkt yu kwaliti fɔ liv. Fɔ liv wit sɔm kayn sik lɛk pen ɛn de fil se de kansa de prɛd nɔr izi. Bɔt na sɔm advays dɛn we go ɛp yu:

• It fayn: Kɔmplikɛshɔn dɛn we kin kam frɔm di bon mɛtastas kin afɛkt yu apɛtit. Tɔk to pɔsin we sabi bɔt it fɔ mek i gɛt wan plan fɔ it fayn fayn wan we go wok fɔ yu.
• Tink bɔt di program dɛm fɔ mek yu nɔ gɛt kansa: Yu dɔn bi pɔsin we dɔn sev frɔm kansa frɔm di de we dɛn no se yu gɛt am. Naw we yu de dil wit bon mɛtastas, yu na di sem. Sɔntɛm program ɛn sɔpɔt grup dɛn de we de ɛp pipul dɛn we de na di sem tin lɛk yu.
• Aks bɔt palliativ kia:Bɔrku tɛm, di fɔs sayn wae de sho se di bon mɛtastas na di bon pen. Dis pen kin tranga ɛn i kin afɛkt yu kwaliti fɔ liv. Palliative care inklud pen mεdikeshכn εn כda pen mεnejmεnt sכpכt. Palliative care inklud bak saikɔlɔjik kɔyl fɔ ɛp yu fɔ manej di imɔshɔnal chalenj dɛm wae kin kam wae yu gɛt kansa wae nɔr de mɛn.
• Luk insay klinik trial: Risach pipul dɛn de luk fɔ nyu we fɔ trit bon mɛtastas frɔm difrɛn kayn kansa. Aks yu dɔktɔ bɔt klinik trial dɛm we go fayn fɔ yu.

A fɔ tink bɔt aw fɔ kia fɔ pipul dɛn we de na os?

I dipen pan yu kɔndishɔn. If yu dɔktɔ tink se yu kansa nɔ go wɛl if yu kɔntinyu fɔ trit yu, ɛn yu gɛt siks mɔnt ɔ smɔl pas dat fɔ liv if dɛn stɔp di tritmɛnt, i kin tɛl yu fɔ kia fɔ yu na os . Hospice care de pe atɛnshɔn pan yu bɔdi kɔmfɔt, fri frɔm pen, ɛn fɔ manej ɔda sayn dɛm.

Ustɛm a fɔ go to mi dɔktɔ?

If yu simptom dɛm fɔ bon mɛtastas de wɔs, fɔ ɛgzampul, if yu gɛt pen we yu nɔ ebul fɔ kɔntrol ivin wit mɛrɛsin we dɛn gi yu, go to yu dɔktɔ wantɛm wantɛm. Mɛmba se yu nɔr nid fɔ liv wit di bad bad pen wae de kam wit bon mɛtastas. Yu dɔktɔ go gi yu mɛrɛsin fɔ mek yu nɔ fil pen ɛn ɔda tritmɛnt dɛn we nɔ go afɛkt yu kwaliti layf, ivin di we aw yu go ebul fɔ de wit di wan dɛn we yu lɛk.

Ustɛm a fɔ go na di Imejɛnsi Rum?

If yu gɛt sayn dɛm fɔ kɔmpreshɔn na yu spɛnal kɔd, yu fɔ kɔl 911 ɔ go na di imejensi rum wantɛm wantɛm. Dɛn sayn ya na:

• If yu leg, yu fut in fut, ɔ yu bɛlɛ we de dɔŋ fil lɛk se yu nɔ gɛt bɛtɛ trɛnk ɔ yu nɔ gɛt bɛtɛ trɛnk.
• If i nɔ izi fɔ yu fɔ muv yu leg dɛn.
• If yu nɔ ebul fɔ kɔntrol yu urinate ɔ defecation.
• If yu nɔ ebul fɔ pis atɔl.

If dɛn nɔ trit am, di kɔmpreshɔn we di spaynal kɔd kin mek i nɔ ebul fɔ waka, so yu fɔ no bɔt dɛn sik ya gud gud wan.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Fɔ no se yu gɛt bon mɛtastasis, we yu dɔn ɔlrɛdi de dil wit kansa, kin afɛkt yu kwaliti layf mɔ. Na sɔm kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• Uswan pan mi bon dɛn dɔn ful-ɔp wit kansa sɛl dɛn naw?
• Aw fɔ gɛt bon kansa kin afɛkt mi ɔl di prɔgnosis?
• Us tritmɛnt ɔ kɔmbayn tritmɛnt dɛn go ɛp mi?
• Yu tink se tritmɛnt dɛn kin stɔp di bon mɛtastas fɔ mek i nɔ go skata to ɔda bon dɛn?
• Wetin na di opshɔn dɛm fɔ manej mi bon pen?
• Aw a go ridyus di prɔblɛm we a gɛt fɔ brok bon?

Wetin na di difrɛns bitwin Bɔn Kansa ɛn Bɔn Mɛtastasis?

Dis na sɔntin we kin mek bɔku pipul dɛn kɔnfyus.

• Bɔn kansa na wan kayn kansa we kin bigin na yu bon dɛm, lɛk ɔstiosarkoma ɔ Ewing sarkoma .
• Bɔn mɛtastasis na we kansa we bigin ɔdasay na yu bɔdi leta go skata to yu bon dɛm.

Bɔn mɛtastasis na wan sayn fɔ mɛtastas kansa. Dɛn kin tɛl yu se yu gɛt bon mɛtastasis, di fɔs tɛm we yu no se yu kansa dɔn skata frɔm usay i bigin. Di nyus kin mek wi at pwɛl ɛn mek wi at pwɛl. Wetin pas dat, fɔ no se di bon mɛtastasis kin mek yu fil pen ɔltɛm ɛn i kin afɛkt yu kwaliti layf kin mek yu fil bad mɔ. Yu go de wɔri ɛn fred bɔt wetin yu go ɛkspɛkt nɛks. Bɔt mɛmba se yu dɔktɔ dɛn de fɔ lisin to yu ɛn ɔndastand wetin de mɔna yu. Dɛn kin ɛp yu wit ɔltin frɔm aw fɔ kɔntrol yu pen to fɔ ɛksplen wetin fɔ ɛkspɛkt if yu kansa skata.

Fɔ dɔn, mɛsej we yu kin kɛr go na os:

Pan ɔl we di bon mɛtastasis na siriɔs sik, we dɛn de fɔ mɛn am.

• Di tin we impɔtant pas ɔl na fɔ nɔ panik ɛn fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan.
• Tritmɛnt dɛn de fɔ kɔntrol pen ɛn fɔ mek pɔsin gɛt gud kwaliti layf.
• Nɔto yu wan de. Yu gɛt famili, padi dɛn, dɔktɔ dɛn, ɛn pipul dɛn we de wok fɔ yu wɛlbɔdi biznɛs fɔ ɛp yu.
• Fɔ de pɔsitiv ɛn fɔ gɛt strɔng maynd rili impɔtant pan dis joyn.

If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, nɔ fred fɔ aks yu dɔktɔ. I go ɛksplen ɔltin to yu.

` Kεnsar, bon mεtastas, bon pen, kεnsar spred, kεnsar tritmεnt, kalsiכm inkrεs, spεnal kכmpreshכn