Yu no bɔt Bosutinib pils? Dɛn tin ya rili impɔtant fɔ mɛn kansa!

Yu dɔktɔ dɔn gi yu ɔ pɔsin we de nia yu di mɛrɛsin we dɛn kɔl `Bosutinib`? Ɔ yu want fɔ no mɔ bɔt dis mɛrɛsin? So tide, lɛ wi tɔk bɔt dis drɔg `Bosutinib` ditayli ɛn insay wan rili simpul we. Fɔ ɔndastand dɛn kayn mɛrɛsin ya kɔrɛkt wan kin ɛp bɔku fɔ mek di tritmɛnt go bifo.

Wetin na dis mɛrɛsin? Wetin na Bosutinib?

Fɔ tɔk am simpul wan, Bosutinib na wan mɛrɛsin we de tɔch sɔm prɔtin dɛn we de na di kansa sɛl dɛn ɛn stɔp dɛn fɔ gro . Spɛshal wan, dɛn kin yuz am mɔ fɔ trit wan kayn blɔd kansa we dɛn kɔl Chronic Myelogenous Leukemia (CML). I de pan wan klas ɔf drɔgs we dɛn kɔl Targeted Therapy. Dis min se dis drɔg nɔ jɔs de afɛkt di sɛl dɛn in jɛnɛral, bɔt i de afɛkt di kansa sɛl dɛn spɛshal wan.

Yu kin ebul fɔ mek di dɔktɔ gi yu dis mɛrɛsin ɔnda di brand nem ``BOSULIF.'' Dat na wan brand nem we bɔku pipul dɛn sabi fɔ dis mɛrɛsin.

Bɔt mɛmba se sɔntɛnde dɔktɔ dɛn kin yuz dis mɛrɛsin fɔ ɔda sik dɛn bak. So i bɛtɛ fɔ aks yu dɔktɔ ɔ fama ɛksaktɔli wetin mek dɛn dɔn gi yu dis mɛrɛsin.

Wetin yu fɔ tɛl yu dɔktɔ bifo yu bigin dis mɛrɛsin?

Dis rili impɔtant. Bifo yu bigin fɔ tek Bosutinib, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni wɛlbɔdi prɔblɛm we yu go gɛt. Dis go ɛp dɛn fɔ disayd if dis mɛrɛsin fayn fɔ yu ɛn wetin yu fɔ tek tɛm wit.

Na sɔm tin dɛn we wi fɔ rili tɔk:

• If yu gɛt dayabitis ( ay blɔd shuga lɛvɛl).
• If yu gɛt `At Sik` .
• If yu gɛt `High Blood Pressure` .
• If yu gɛt sik na yu kidni .
• If yu gɛt liva sik .
• If yu dɔn gɛt wan ɔda kayn alɛji fɔ Bosutinib, ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl.
• If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ . Dis rili impɔtant!
• If yu na mama we de gi pikin in bɛlɛ .

I rili impɔtant fɔ yu yon sef fɔ tɛl di dɔktɔ we yu nɔ ayd dis infɔmeshɔn, okay?

Aw a fɔ yuz dis mɛrɛsin?

Okay, naw mek wi si aw fɔ yuz dɛn `Bosutinib` pils ya ɛksaktɔli. Di tin we impɔtant pas ɔl na fɔ tek di mɛrɛsin jɔs lɛk aw di dɔktɔ tɛl yu.

• Dis pil fɔ tek bay mɔt wit wan glas wata .
• Fɔ fala di instrɔkshɔn dɛn we de na di prɛskrishɔn lɛbl ɛksaktɔli.
• Dɛn fɔ tek dis mɛrɛsin wit it. Nɔ tek am we yu ɛmti bɛlɛ. If yu tek am wit it, i kin ɛp fɔ mek di mɛrɛsin tek am bɛtɛ ɛn i kin mek sɔm pan di bad tin dɛn we kin apin to am nɔ bɔku.
• Nɔ kɔt, krɔs, ɔ chew di pil. Swɛla di pil ɔl.
• Nɔ tek dis mɛrɛsin wit grep jus. Grep na frut we fiba big ɔrɛnj. Di jus we dɛn mek wit dis frut kin riak wit dis mɛrɛsin ɛn afɛkt di we aw i de wok. So tek tɛm mɔ bɔt dis.
• If yu de tek H2 blɔk (e.g., cimetidine, famotidine, ranitidine) ɔ antacids (e.g., Digene, Gelusil) fɔ at bɔn ɔ gastritis , yu fɔ tek dɛn 2 awa bifo ɔ 2 awa afta bosutinib. Dis min se at le 2 awa gap fɔ de bitwin fɔ tek dɛn tu mɛrɛsin ya. Aks yu dɔktɔ ɔ fama fɔ no mɔ.
• Tek yu mɛrɛsin ɔltɛm ɛn di rayt tɛm. Nɔ tek pas di mɔni we yu dɔktɔ tɛl yu fɔ tek, ɔ tek am bɔku tɛm.
• Nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.

If yu de gi pikin dɛn dis mɛrɛsin, yu fɔ tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am ɛn fala in advays. Sɔntɛm dɛn nid spɛshal kia.

If yu tink se yu dɔn tek tumɔs pan dis mɛrɛsin bay mistek, kɔl Pɔyzin Kɔntrol Sɛnta ɔ di Imejɛnsi Rum we de nia yu wantɛm wantɛm.

Di tin we impɔtant pas ɔl: Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ gi dis mɛrɛsin to ɔda pɔsin fɔ ɛni rizin, ilɛksɛf da pɔsin de gɛt di sem sayn dɛn we yu gɛt.

Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?

If yu nɔ gɛt wan doz fɔ mɛrɛsin, dat kin apin to ɛnibɔdi. If dat apin, nɔ wɔri.

• Tek di doz we yu mis as yu mɛmba.
• Bɔt if i nɔ rich 12 awa te yu tek di nɛks doz, nɔ tek di doz we yu mis. Skip am ɛn jɔs tek di nɛks doz na di tɛm we dɛn dɔn sɛtul.
• Nɔ ɛva tek dabl doz mɛrɛsin. We yu du dat, dat kin mek yu gɛt mɔ sayd ɛfɛkt.

Us ɔda tin dɛn kin miks wit dis mɛrɛsin?

Bosutinib kin intarakt wit sɔm ɔda mɛrɛsin dɛm, it dɛm, ɛn ɛbul sɔpɔtmɛnt dɛm we yu kin de tek. Dɛn intarakshɔn ya kin mek di Bosutinib wok fayn ɔ i kin mek di risk fɔ gɛt sayd ɛfɛkt dɛn go ɔp.

Bosutinib kin intarakt wit dɛn tin ya:

• Sɔm antibayɔtiks (e.g. siproflɔksasin, klaritromaysin, ɛrythromycin) .
• Sɔm antifɔngal dɛn (e.g. flukonazɔl, kɛtokonazɔl, itrakonazɔl) .
• Sɔm mɛrɛsin dɛn we de mek pɔsin nɔ ebul fɔ du bad (e.g. carbamazepine, phenobarbital, phenytoin) .
• `Sɔm mɛrɛsin fɔ bɛlɛ prɔblɛm` (e.g. `Proton Pump Inhibitors` ɛn `H2 blɔk` lɛk `cimetidine`, `famotidine`, `ranitidine`, `omeprazole`, `pantoprazole`)
• Sɔm mɛrɛsin dɛn we dɛn kin yuz fɔ trit HIV infɛkshɔn (e.g. amprenavir, atazanavir, ritonavir) .
• Grepfruit jus (a don se dis bifo, bot a go se am bak!)
• Sɔplɛnt dɛn we dɛn mek wit di ɔyl we dɛn kɔl Sɛnt Jɔn Wɔt (sɔm pipul dɛn kin yuz dɛn tin ya fɔ mek dɛn gɛt wɛlbɔdi).
• Bɔku ɔda mɛrɛsin dɛn (e.g., amiodarone, diltiazem, verapamil, rifampin).

Dis list nɔ kɔmplit. Sɔntɛm ɔda mɛrɛsin dɛn de. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (we dɛn gi yu, we yu de bay, we yu de yuz ɛbul, vaytamɛn, ɔ it we yu de it). Dɔn bak, tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz ɔda drɔgs. Dɔn i kin plan yu tritmɛnt akɔdin to dat.

Wetin a fɔ tek tɛm we a de tek dis mɛrɛsin?

I impɔtant fɔ pe atɛnshɔn to ɛni chenj na yu bɔdi we yu de tek Bosutinib.

• Yu go nid fɔ de du blɔd tɛst ɔltɛm . Dis go ɛp yu dɔktɔ fɔ si aw di mɛrɛsin de afɛkt yu bɔdi, if yu ɔgan dɛn lɛk yu liva ɛn kidni de wok fayn, ɛn if ɛni chenj de na di tin dɛn we de insay yu blɔd.
• Dis mɛrɛsin kin mek yu gɛt brus ɔ blɔd. If yu notis ɛni kayn brus we nɔ kɔmɔn, yu gɔm de blɔd, yu nos de blɔd, ɔ yu de blɔd, tɛl yu dɔktɔ wantɛm wantɛm.
• If yu gɛt fiva, kol, trot we de at , ɔr yu gɛt sayn dɛm fɔ infekshɔn lɛk kol ɔ kɔf, nɔr de mɛrɛsin fɔ yusɛf. Kɔl yu dɔktɔ wantɛm wantɛm fɔ advays. Dis mɛrɛsin kin mek yu bɔdi nɔr ebul fɔ fɛt sik. So, tray fɔ de fa frɔm pipul dɛn we sik.
• Speshal atɛnshɔn bɔt bɛlɛ:
• Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin.
• Nɔ gɛt bɛlɛ fɔ at le 2 wik afta yu dɔn stɔp di pil.
• uman dεm we de plan fכ bεlε כ tink se dεn kin bεlε fכ tεl dεn dכkta kwik kwik wan. Dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs sayd ɛfɛkt. Aks yu dɔktɔ ɔ fama fɔ no mɔ.
• Fɔ tɔk bɔt aw fɔ gi pikin in bɛlɛ: Nɔ gi yu pikin in mama in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ at le 2 wik afta yu dɔn stɔp di mɛrɛsin.
• Fɔ bɔn pikin: Dis mɛrɛsin kin afɛkt di we aw yu ebul fɔ bɔn pikin. If yu de wɔri bɔt dis, tɔk to yu dɔktɔ.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?

Lɛk ɛni mɛrɛsin, Bosutinib kin mek sɔm sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Sɔm sayd ɛfɛkt dɛn kin siriɔs ɛn yu fɔ tɛl yu dɔktɔ wantɛm wantɛm if yu gɛt dɛn. Sɔm nɔ kin siriɔs ɛn dɛn kin go afta sɔm dez.

Di sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm:

• Alɛji: Skin de rɔsh, it, ayv, swel na in fes, lip, ɔ tong. If dɛn sayn ya apin, go to dɔktɔ wantɛm wantɛm.
• Bak pen ( bad bad, nɔ kɔmɔn).
• Stul dɛn we gɛt blɔd ɔ blak, we gɛt tar . Dis kin bi sayn fɔ blɔd we de insay pɔsin in bɔdi.
• Sivɛri dayarɛa .
• Diziz (we kin rili bad, we kin apin ɔltɛm).
• Ɛd pen (we rili bad, we pɔsin nɔ kin ebul fɔ bia).
• Sayn dɛm fɔ at atak: Trɔbul fɔ blo, pen ɔ tayt na yu chɛst, nɛk, bak, ɔ yu an.
• Sayn dɛm wae de sho se yu at nɔr de wok fayn: yu de blo shɔt, yu at de bit fast ɔr nɔr de bit ɔltɛm, yu de gɛt bɔku bɔku wet wantɛm wantɛm; swel na di ankles, fut, an.
• `Infεkshכn sayn dεm`: fiva, kol, kכf, trot we de at, pen כ i at fכ pis.
• Joint pen ( bad bad wan).
• `Kidni injuri sayn dεm`: chenj na di כmכnt we di urine de prodyuz (dεn dכn dכn כ inkrεs bכku bכku wan).
• `Stɔl we gɛt layt kɔlɔ` .
• Sayn dɛm fɔ injuri na di liva: Dak yɔlɔ ɔ brawn urine, jenɛral sik filin ɔr lɛk flu, nɔr kin want fɔ it, rayt ɔpa bɛlɛ kin pen, yu yay ɔ skin kin yɔlɔ (jaundice).
• `Lכw rεd bכdi sεl kכnt (Anemia)`: I at fכ brith, fεnt, fil diziz, fil lεk yu go fכl bכku tεm, fil fכ taya כ wik we yu nכmal.
• Nɔs (we kin rili bad, we kin kɔntinyu fɔ de).
• `Rɛd ɔ dak brawn urine` .
• Bɛlɛ pen ( bad bad wan).
• `Blɔd ɔ brus we nɔ kɔmɔn`.
• `Swɛlin we nɔ kɔmɔn` .
• Vɔmit (we kin rili bad, we kin kɔntinyu fɔ de).

Sayd ɛfɛkt dɛn we nɔ kin nid fɔ gɛt mɛrɛsin (bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de ɔ we de mɔna yu):

• `Kɔnstipɛshɔn` .
• `Taya we pɔsin taya` .

Mɛmba se dis list nɔ gɛt ɔl di bad tin dɛn we kin apin. If yu notis ɛnitin we nɔ kɔmɔn ɔ we difrɛn, tɛl yu dɔktɔ bɔt am.

Aw a fɔ kip mi mɛrɛsin?

I rili impɔtant bak fɔ kip yu mɛrɛsin fayn fayn wan.

• Kip am usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich.
• Stɔr am na rum tɛmpracha. Dat min se, i go kol bitwin 20 ɛn 25 digri sɛlshiɔs (68 ɛn 77 digri F). Nɔ put am na say we wam pasmak, kol, ɔ wet pasmak.
• Nɔ yuz mɛrɛsin dɛn we dɔn pas di de we dɛn fɔ dɔn. Trowe dɛn go.

Aw yu kin trowe mɛrɛsin dɛn we yu nɔ yuz ɛn we dɔn pas?

Nɔto ɔltɛm i fayn fɔ jɔs trowe mɛrɛsin dɛn we dɔn pas, we yu nɔ yuz na di dɔti ɔ flush dɛn dɔŋ di tɔylɛt. Dɛn kin ambɔg di envayrɔmɛnt.

• Di bɛst tin fɔ du na fɔ gi dɛn mɛrɛsin ya to ``mɛdisin tek-bak program.'' Yu kin aks yu famasi ɔ lokal wɛlbɔdi ɔtoriti dɛn if dɛn gɛt dɛn kayn program ya.
• If yu nɔ ebul fɔ fɛn dis kayn program, chɛk di mɛrɛsin paket ɔ di liflet we de insay fɔ si if i gɛt instrɔkshɔn bɔt aw fɔ trowe am na dɔti ɔ tɔylɛt. If yu nɔ shɔ, aks yu dɔktɔ ɔ fama.
• If yu shɔ se i sef fɔ trowe di dɔti, pul di mɛrɛsin na di bɔtul ɔ paket we i kam insay, miks am wit sɔntin lɛk kɔfi grɔn we dɛn dɔn yuz, pusi dɔti, ɔ dɔti, ɛn put am insay bag ɔ kɔntena we dɛn tayt tayt ɛn trowe am na di dɔti.

Dis liflet na sɔmari nɔmɔ. If yu gɛt ɛni ɔda kwɛstyɔn bɔt Bosutinib, duya tɔk to yu dɔktɔ, fama, ɔ ɔda pɔsin we de kia fɔ yu wɛlbɔdi biznɛs.

Di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so lɛ wi mɛmba yu bak bɔt sɔm pan di tin dɛn we wi bin tɔk bɔt we yu nid fɔ mɛmba.

• Bosutinib na spɛshal mɛrɛsin we dɛn kin gi fɔ kansa lɛk kronik myelogenous leukemia (CML).
• Dis mɛrɛsin fɔ tek wit it . Dɛn nɔ fɔ kɔt am, krɔs am, ɔ it am. Nɔ tek wit grep jus.
• Yu fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek, ɛni ɔda sik we yu gɛt, ɛn if yu gɛt bɛlɛ ɔ yu de gi pikin bɔbi.
• Nɔ gɛt bɛlɛ we yu de tek di pil. Tek tɛm fɔ 2 wik afta yu dɔn stɔp.
• If yu gɛt blɔd we nɔ kɔmɔn, fiva, skin rɔsh, i nɔ izi fɔ blo, ɔ yu gɛt sayn dɛn fɔ janda, tɛl yu dɔktɔ wantɛm wantɛm.
• Mek dɛn du blɔd tɛst di rayt tɛm.
• Nɔ stɔp fɔ tek di mɛrɛsin if yu dɔktɔ nɔ advays yu.

Wi de wish yu fɔ wɛl kwik kwik wan! A op se dis infɔmeshɔn go ɛp yu.

` Bosutinib, Bosulif, CML, Kronik Maylojen Lukimiya, Kansa Tritmɛnt, Kansa Mɛdikeshɔn, Sayd Ifɛkt